This invention discloses a tea
pectin polysaccharide and its application in
immune regulation and prevention of
colitis, relating to the field of
biomedical technology. The invention provides a tea
pectin polysaccharide whose main
chain structure is composed of (1→4)-α-D-GalpA-(1→) linked together, with the repeating
structural unit being (1→4)-α-D-GalpA. The (1→4)-α-D-GalpA-(1→) residues of the tea
pectin polysaccharide exhibit
acetylation at positions O-2 and O-3, and methyl esterification at position C-6, with a degree of
acetylation of 14.80% and a degree of methyl esterification of 42.47%. The main
chain structure of the pectin polysaccharide after
oxidative degradation is composed of α-D-G... The structure consists of alpA-(1→4)-α-D-GalpA-(1→link and →4)-α-D-GalpA-(1→4)-β-D-GalpA links, with the linking sites located at positions O-4. The tea pectin polysaccharide of this invention and its related preparations exhibit excellent immunomodulatory effects, playing a significant role in anti-inflammatory and anti-
cancer processes. It is particularly valuable in the prevention and treatment of
colitis, cardiovascular diseases, immune diseases, neurodegenerative diseases, and other chronic diseases.