587 results about "Compounded preparations" patented technology

The invention belongs to the technical field of medicines, and particularly relates to a pyruvate-containing composite preparation as well as a preparation method and application thereof. The composite preparation containing pyruvate is prepared from the following components in percentage by mass: 0.02 to 0.04 percent of a compound A, 0.05 to 0.1 percent of pyruvate, 0.2 to 2 percent of sodium dihydrogen phosphate, 0.2 to 2 percent of disodium hydrogen phosphate, 0.7 to 0.9 percent of sodium chloride and the balance of water for injection, the structural formula of the compound A is as follows: # imgabs0 #. The compound A and pyruvate in the compound preparation interact with each other, so that lung inflammatory response can be inhibited, the level of inflammatory factors can be reduced, and lung edema can be relieved.

The invention relates to the field of animal breeding, and discloses a pig beta defensin compound preparation which comprises pig beta defensin PBD1, PBD2 and PBD114, and the weight ratio of the PBD1 to the PBD2 to the PBD114 is 1: 1: 1. The porcine beta defensin PBD1, the porcine beta defensin PBD2 and the porcine beta defensin PBD114 are recombinant proteins, and are respectively expressed in escherichia coli BL21 (DE3) PLysS competent cells by a pET-32a expression vector. Through the synergistic effect of the defensins PBD1, PBD2 and PBD114, the minimum inhibitory concentration (MIC) of the EPEC is reduced to 18.75 mu g / mL from 75 mu g / mL of single defensins, and is reduced by 75%; within 24 hours, the bacteriostasis rate of the compound preparation reaches 90%, and the inhibition effect on EPEC is remarkably improved.

The invention discloses an edible and medicinal composition for dispelling effects of alcohol and protecting liver as well as a preparation method and application thereof, and belongs to the technical field of functional foods. The composition consists of the following raw materials in parts by weight: 1-8 parts of ampelopsis grossedentata extract freeze-dried powder, 1-8 parts of astragalus membranaceus extract freeze-dried powder, 1-5 parts of kudzu vine root extract freeze-dried powder, 1-8 parts of hawthorn extract freeze-dried powder and 1-5 parts of cassia seed extract freeze-dried powder. The composition is designed according to a multi-component synergistic interaction principle, and the functions of protecting the liver and dispelling the effects of alcohol are enhanced through targeted interaction of active ingredients such as ampelopsis grossedentata flavone, puerarin and astragaloside; the compound preparation has the compound effects of protecting the liver, dispelling the effects of alcohol, resolving dampness, resisting oxidative stress, regulating lipid metabolism and the like, can remarkably relieve the problems of acute and chronic liver injury and metabolic disorder caused by alcohol intake, and meets the food-grade safety standard and the medicinal activity requirement; the important application prospect is realized in the aspect of preparing a preparation for relieving alcoholic liver injury and improving the liver detoxification function.

The invention relates to the technical field of medicines, and particularly discloses a compound antihypertensive pharmaceutical composition. The pharmaceutical composition provided by the invention selects sacubitril valsartan sodium and indapamide as active ingredients, and within a prescription dosage range limited by the application, the two medicines can fully realize an antihypertensive effect through a synergistic effect, and the renal function of a patient is effectively improved. Through cooperation of the two components, the hypertension symptom of a patient can be effectively controlled, the adverse reaction is not obvious, and the compliance of the patient can be improved by adopting the compound preparation, so that the control on the blood pressure of the patient is enhanced.

The invention discloses a preparation method of eye drops for treating glaucoma, cataract and vitreous opacification. The eye drops comprise the following components: berberine, N-acetyl carnosine and lycium barbarum polysaccharide. The specific formula comprises the following components: 0.1%-0.5% of berberine, 1%-3% of N-acetyl carnosine and 0.5%-2% of lycium barbarum polysaccharide. The invention belongs to the technical field of ophthalmic pharmaceutical preparations, and solves the problems that in the prior art, glaucoma, cataract and vitreous opacity generally need to be separately taken, the research on compound preparations is less, and the components possibly interact with one another.

The invention belongs to the technical field of traditional Chinese medicine preparation, and particularly relates to a peach kernel and safflower four-ingredient decoction compound preparation and a preparation method and a quality control method thereof. The invention provides a preparation method of a peach kernel and safflower four-component decoction compound preparation by screening and optimizing an enrichment method of volatile oil in extraction, concentration, inclusion and drying processes on the basis of an ancient water decoction process. According to the peach kernel and safflower four-drug decoction compound preparation prepared by the invention, the quality consistency with a reference sample is realized, including the consistency of each content index in the compound preparation with the reference sample and the consistency of a fingerprint spectrum with the reference sample; especially, characteristic peaks of volatile components-ligustilide, senkyunolide I and senkyunolide A are presented in the fingerprint spectrum, and the consistency of the content of the volatile oil is determined. Moreover, the quality control method provided by the invention is expected to be used for quality control of industrial large-scale production of a classic famous prescription, namely the peach kernel and safflower four-ingredient decoction compound preparation, and has a good application prospect.

The invention discloses a gradient alcohol extraction preparation method of compound honeysuckle flower drops for improving T cell activity, and relates to the technical field of traditional Chinese medicine compound preparations, honeysuckle flower and radix astragali are selected for pretreatment, an ethanol aqueous solution and an interaction regulating agent are added for infiltration, an online traditional Chinese medicine compound preparation HPLC is adopted for dynamic alcohol concentration adjustment and temperature extraction under monitoring of the traditional Chinese medicine compound preparation, the method disclosed by the invention has the advantages that the interaction regulating agent is added in the raw material infiltration stage to block bad interaction among active components, and the online monitoring system is utilized to dynamically adapt the ethanol concentration and the extraction temperature to realize step-by-step efficient dissolution of the multi-polar components; the antioxidant is matched to inhibit oxidation of thermosensitive components, and the solubilizer assists dissolution of insoluble components, so that the core defect that synergistic extraction of multi-polar active components, degradation of the thermosensitive components and interaction inhibition of the components in the compound honeysuckle flowers cannot be considered in the prior art is overcome, and loss or antagonism of the active components is effectively avoided.

The invention relates to the technical field of traditional Chinese medicine formulas for treating hypertension, in particular to a traditional Chinese medicine compound preparation for treating liver-yang hyperactivity type hypertension or yin deficiency and yang hyperactivity type hypertension as well as a preparation method and application of the traditional Chinese medicine compound preparation for treating liver-yang hyperactivity type hypertension or yin deficiency and yang hyperactivity type hypertension. The medicinal materials comprise gastrodia elata, uncaria, fried stiff silkworm, cornu bubali, concha haliotidis, selfheal, radix cyathulae, salted eucommia ulmoides, salted semen plantaginis and fried spina date seed. The preparation method comprises the following steps: decocting a required amount of buffalo horn with water to obtain a buffalo horn decoction; soaking other medicinal materials except the uncaria in water, decocting the soaked medicinal materials and the cornu bubali decoction for two to three times, adding the uncaria into the decoction five to seven minutes before the last decoction, and combining the decoction to obtain the traditional Chinese medicine compound preparation. The traditional Chinese medicine compound preparation disclosed by the invention has a blood pressure lowering effect on people with different symptoms of hypertension, is stable in blood pressure lowering and reliable in effect, and has the effects of nourishing yin, suppressing yang, calming the liver and calming the heart.

The invention relates to the technical field of traditional Chinese medicine preparations, in particular to a traditional Chinese medicine compound preparation for preventing and treating sepsis based on intestinal treatment and gasification regulation and a preparation method and application of the traditional Chinese medicine compound preparation. The composition is prepared from the following medicinal materials in parts by weight: 3 to 10 parts of rheum officinale, 5 to 10 parts of fructus aurantii, 5 to 10 parts of radix aucklandiae, 10 to 15 parts of fructus gardeniae, 10 to 15 parts of dandelion, 10 to 15 parts of fructus forsythiae, 10 to 15 parts of herba artemisiae scopariae, 10 to 15 parts of rhizoma atractylodis, 10 to 15 parts of poria cocos, 10 to 15 parts of radix paeoniae rubra, 10 to 15 parts of radix salviae miltiorrhizae, 15 to 20 parts of astragalus membranaceus, 10 to 15 parts of rhizoma anemarrhenae, 10 to 15 parts of fructus cannabis, 10 to 15 parts of semen pruni and 3 to 6 parts of raw liquorice. The traditional Chinese medicine compound provided by the invention considers the treatment rules of relaxing bowels, purging heat, promoting qi circulation, removing stagnation, detoxifying, dispersing blood stasis, reinforcing qi, nourishing yin and the like, and also considers the effects of relaxing bowels, regulating qi and supporting healthy qi, various diseases of sepsis patients can be remarkably improved through the synergistic effect of the medicines in the formula, and the traditional Chinese medicine compound especially has an obvious curative effect on gastrointestinal dysfunction. A novel traditional Chinese medicine treatment thought is provided for clinical treatment of sepsis diseases.

The invention discloses a preparation method of 20 (E)-ginsenoside F4 and application of the 20 (E)-ginsenoside F4 in preparation of anti-liver injury medicines, and relates to the technical field of biological medicines. The rare ginsenoside 20 (E)-ginsenoside F4 is prepared and purified from ginsenoside Re through an acid catalytic conversion method, and the rare ginsenoside 20 (E)-ginsenoside F4 shows remarkable advantages and wide prospects in research and development of liver protection drugs. The monomer has strong liver protection activity, complies with the development trend of monomeric compound preparations, and provides efficient active ingredients for liver protection drugs. The 20 (E)-ginsenoside F4 with efficient activity, excellent safety and environment-friendly preparation characteristics can be widely applied to preparation of liver protection drugs or pharmaceutical compositions, especially drugs or pharmaceutical compositions for treating liver injury caused by chemotherapeutic drugs.

The application provides a Chinese medicine compound preparation for preventing and treating respiratory tract infection of livestock and poultry, a preparation method and application, and relates to the technical field of animal medicine. The Chinese medicine compound preparation is composed of 10 Chinese medicines, i.e. honeysuckle, forsythia, inula flower, platycodon grandiflorum, euphorbia helioscopia, xiaochangqing, fresh eucalyptus globulus, fried stemona, cat's claw and augustifolia, follows the principle of Chinese medicine syndrome differentiation and treatment, is reasonably matched, and the medicines are coordinated with each other to increase the efficacy. The Chinese medicine compound preparation can significantly reduce the levels of TNF-alpha and IL-6 in serum, increase the level of IFN-gamma, obviously alleviate the clinical symptoms of livestock and poultry respiratory tract infection, reduce the mortality, has a good treatment effect on the related diseases of livestock and poultry respiratory tract infection, can improve the drug resistance of antibiotic drugs, reduce the drug residues of chemical agents in livestock and poultry, and guarantees the health of livestock and poultry and the safety of animal source food.

The invention provides a memantine hydrochloride sustained-release pellet preparation with simple components and a compound capsule containing the memantine hydrochloride sustained-release pellet and donepezil, and provides a preparation method of the memantine hydrochloride sustained-release pellet preparation. The compound capsule has equivalent dissolution effect with a reference preparation # imgabs0 #, is good in stability and simple in preparation process, overcomes the defects of complex components and tedious process of the existing preparation, is convenient to operate, and reduces the manufacturing cost.

The method comprises the following steps: dissolving lipoic acid and a drug in an organic solvent to form a homogeneous solution, dropwise adding deionized water while stirring, then adding a reducing agent, initiating lipoic acid polymerization and drug co-assembly in situ at 20-40 DEG C to form a drug-loaded micelle solution, and carrying out freeze drying on the drug-loaded micelle solution to obtain the nano-preparation drug based on polylipoic acid. And dialyzing and purifying to obtain the nano preparation medicine based on polylipoic acid. The preparation method is characterized in that lipoic acid has dual characteristics of a drug carrier matrix and a dynamic crosslinking monomer, carrier synthesis and efficient drug encapsulation are synchronously realized through one-step in-situ polymerization-co-assembly, and the technical bottleneck that a traditional nano-carrier needs pre-synthesis and step-by-step drug loading is broken through. The method has the following practicability: (1) the process is simple and efficient, complex equipment is not needed, and reaction conditions are mild; (2) the drug loading performance is excellent, and the particle size is uniform and adjustable (50-300 nanometers); (3) a polylipoic acid skeleton endows the nano-drug preparation with environmental responsiveness, and intelligent drug release can be realized; and (4) the method is suitable for hydrophobic drugs and compound preparations. The method provides a high-load, high-stability and stimuli-responsive nanocrystallization solution for hydrophobic drug delivery, and has application value in the field of nano-medicines.

The invention discloses a traditional Chinese medicine composition for treating fatty liver diseases related to metabolic dysfunction. The traditional Chinese medicine composition is prepared from the following raw material medicines: Qu fructus aurantii, lotus leaves, semen cassiae, gynostemma pentaphylla, rhizoma alismatis, rhodiola rosea, radix salviae miltiorrhizae, pseudo-ginseng and rhizoma atractylodis macrocephalae. The traditional Chinese medicine composition and the traditional Chinese medicine compound preparation disclosed by the invention can improve the blood sugar and blood fat levels of fatty liver diseases related to metabolic dysfunction and improve the metabolic level, are remarkable in clinical curative effect, improve the living quality of patients, have the effects of regulating qi, soothing the liver, tonifying the spleen and removing stasis, slow down liver fibrosis by improving blood sugar and blood fat metabolism, and are quick in curative effect and low in price.

The invention relates to the technical field of traditional Chinese medicine detection, in particular to a quality control method of a heart fire clearing lotus seed beverage compound preparation, which comprises the following steps: respectively preparing test solution A-E; based on the test solution A, identifying the scutellaria baicalensis by adopting a thin-layer chromatography; identifying cortex lycii radicis and liquorice based on the test solution B, identifying ginseng based on the test solution C, identifying semen plantaginis based on the test solution D, and identifying lotus seeds based on the test solution E. According to the method, repeated extraction of the reference sample during identification of different medicine flavors can be reduced, and the method has the advantages of clear spots, good separation degree, strong specificity, no background interference and good durability.

The invention provides a pharmaceutical composition and application thereof in preparation of a compound preparation, and belongs to the field of medicines. The pharmaceutical composition comprises a potassium ion channel opener, a 5 alpha-reductase inhibitor and a phosphodiesterase 5 inhibitor. The pharmaceutical composition can synergistically promote treatment of androgen dependent diseases or prevention of complications, and by taking the pharmaceutical composition of minoxidil, finasteride and tadalafil as an example, the effects in a benign prostatic hyperplasia rat model and an androgenic alopecia mouse model are verified, which indicates that the minoxidil, finasteride and tadalafil have a synergistic interaction effect, and the pharmaceutical composition can be used for treating the androgen dependent diseases or preventing the complications. Good clinical application prospects are realized.

The invention belongs to the technical field of traditional Chinese medicine preparations, and particularly relates to a kidney-tonifying and liver-nourishing compound preparation and a preparation method thereof. The compound preparation comprises 5-15 parts of roasted herba epimedii, 5-15 parts of fructus cnidii, 50-70 parts of roasted radix astragali and 10-30 parts of pulp of dogwood fruit. The traditional Chinese medicine composition has remarkable curative effects on various diseases and chronic strain caused by deficiency of liver and kidney and deficiency of blood and essence, such as dizziness, blurred vision, fatigue, swelling and pain of waist, back and limbs, dry mouth and eyes, limb ache and weakness, irregular menstruation, incapability of holding weight or hemiplegia and the like, and has a very good application prospect.

The invention discloses a donepezil and memantine compound sustained release preparation and a preparation process thereof, and belongs to the technical field of pharmaceutical preparations. The preparation consists of a donepezil hydrochloride quick-release layer and a memantine hydrochloride slow-release layer, wherein the quick-release layer comprises donepezil, starch, mannitol and the like, and realizes quick disintegration through granulation of a low-substituted hydroxypropyl cellulose aqueous solution; the slow-release layer comprises memantine, pinoresinol diglucoside, a polylactic acid-glycolic acid copolymer and chitosan, and the slow-release layer and the composite slow-release material have a synergistic effect through a low-temperature grinding technology, so that the degradation of the memantine is inhibited, and the sustained release of the memantine is controlled. The problem that an existing compound preparation is poor in stability is solved, and a safe and effective treatment choice which is taken once a day is provided for a patient suffering from the Alzheimer disease.

The invention discloses an application of two collagen peptides with hematopoietic activity, a collagen hydrolysate containing the collagen peptides and a compound of the collagen peptides. The collagen peptides with hematopoietic activity, the collagen hydrolysate containing the collagen peptides and the compound of the collagen peptides comprise one or a combination of the following polypeptides: 1) a polypeptide of GSAGPpGATGFpGAAGR (p is hydroxyproline), and 2) a polypeptide of which the amino acid sequence is GAAGLpGPK (p is hydroxyproline). The invention also provides a preparation method and application of the collagen peptide with hematopoietic activity and the collagen hydrolysate containing the collagen peptide, the two collagen peptides with hematopoietic activity and the compound thereof have good hematopoietic activity and an effect of relieving hematopoietic inhibition, are non-toxic, can be easily used as functional factors to be added into various health-care foods, and have good health-care effects. Good market prospects are realized in medicine and food industries.

The invention belongs to the field of health care products and biological medicines, and particularly discloses an anti-aging stem cell PQQ cordyceps sinensis ganoderma lucidum anthocyanin compound preparation and application thereof.The preparation is composed of apple stem cell extract, PQQ, cordyceps militaris extract, ganoderma lucidum extract, procyanidine and pharmaceutic adjuvants and can be made into capsules or pills or tablets. The preparation method comprises the following steps: extracting the raw material components, uniformly mixing, adding the procyanidine and the auxiliary materials, performing high-pressure homogenization treatment, and finally preparing different dosage forms. Wherein the preparation of the apple stem cell extract, the cordyceps militaris extract and the lucid ganoderma extract comprises detailed steps. The compound preparation can be used for preparing health care products or medicines for preventing / treating senile nervous system diseases, especially medicines for preventing / improving Alzheimer's symptoms. In addition, the invention also provides a pharmaceutical composition containing the compound preparation and an acetylcholin esterase inhibitor.

The invention relates to the field of pharmaceutical preparations, and discloses a compound preparation composition containing olopatadine and brimonidine for a nasal cavity and a preparation method of the compound preparation composition. The compound preparation composition for the nasal cavity is prepared from the following components in percentage by weight: 0.01 to 0.5 percent of olopatadine and 0.01 to 0.5 percent of brimonidine. According to the compound preparation composition, olopatadine and brimonidine are combined for use, the curative effect is remarkably improved compared with single-drug treatment, a good synergistic interaction effect is shown, multiple pharmacological effects are achieved through one-time drug administration, and drug use convenience and long-term treatment compliance are greatly improved.

The invention relates to the technical field of drug performance testing, and discloses an in-vitro release method of glucocorticoid compound ointment, which comprises the step of performing experiments by adopting a liquid chromatograph and a diffuser. According to the in-vitro release method of the glucocorticoid compound ointment, the same in-vitro release method is adopted to research a compound preparation, so that the operation process is simplified, the time and data problems caused by method difference are reduced, and the analysis efficiency is effectively improved; a set of liquid phase detection method is used for analyzing the compound preparation, so that repeated debugging and frequent switching of detection programs are avoided, the equipment performance is fully excavated, and the liquid phase analysis efficiency is improved; and the method can meet the requirements on sensitivity and distinguishing power of the two components, can accurately discriminate subtle changes of different components, and provides reliable data support for quality control, efficacy evaluation and the like of the compound preparation.

The invention discloses a traditional Chinese medicine composition for treating infantile traumatic swelling and pain. The traditional Chinese medicine composition comprises the following raw material medicines: radix rehmanniae recen, radix paeoniae rubra, angelica sinensis, ligusticum wallichii, herba lycopi, pericarpium citri reticulatae viride, poria with hostwood, liquorice, Chinese starjasmine stem, fried malt and fried endothelium corneum gigeriae galli. The invention also provides a traditional Chinese medicine compound preparation and application thereof in preparation of a medicine for treating infantile traumatic swelling and pain. The composition disclosed by the invention has the effects of promoting blood circulation to remove blood stasis, softening hardness to dissipate stagnation, relieving swelling and pain and promoting swelling fading, is high in effective rate and capable of accelerating the process of rehabilitation treatment or subsequent operative treatment, and has relatively high clinical value.

The present application relates to the field of biological glass, in particular to a kind of composite biological glass and its preparation method and application.The present application uses rhBMP-2, doped antibacterial ion 45S5 bioactive glass and polyethylene glycol-lactide-glycolide polymer compound preparation slow-release antibacterial biological glass, the rhBMP-2 can occur synergistic effect with doped antibacterial ion 45S5 bioactive glass, compared with homologous growth factor can play more optimal synergy with antibacterial ion, so as to have higher antibacterial property and osteogenesis, while having longer slow-release effect in polyethylene glycol-lactide-glycolide polymer.The composite biological glass provided by the present application overcomes the pain points of the prior art for the treatment of oral bone defect, improves the treatment effect, reduces the amount of antibiotic use, and reduces the risk of infection.

A kit (100) and method (200) are provided for administering an active ingredient (112) to a subject to elicit a response. The kit comprises a first container (110) with an active ingredient (112) and a second container (120) with an adjuvant (122). The containers permit the ingredients to be admixed to form a compounded preparation for delivery into the subject's tissue. The active ingredient can comprise an allergen. The kit can also include temperature control and mixing components, potentially involving a third container (130). The method comprises providing the kit (100), admixing the ingredients, and injecting the compounded form into the subject's tissue such as a lymph node. The injection can be monitored and repeated. The approach can elicit various responses such as desensitization according to the type of active ingredient used. Overall, the kit (100) and method (200) provide targeted delivery of active ingredients to efficiently provoke a localized response in the subject.

The invention belongs to the technical field of traditional Chinese medicines, and provides a badger fat compound external preparation for treating radioactive skin injury. According to the traditional Chinese medicine differentiation of radioactive skin injury, the compound preparation is prepared by selecting a method of clearing away heat and toxic materials, eliminating dampness, promoting blood circulation, removing blood stasis, removing slough, promoting granulation, cooling blood and nourishing yin, and comprises the following main components: raw rhubarb, lithospermum, sanguisorba officinalis, aloe, folium isatidis, cottonrose hibiscus leaves, dandelion, badger fat and borneol. The compound preparation is prepared from Chinese herbal medicines and badger fat according to unique pathological characteristics of radioactive skin injury, and has a better treatment effect on radioactive skin injury, especially moderate and severe injury.

This invention relates to the field of quality testing technology for traditional Chinese medicine preparations, specifically providing a method for constructing a fingerprint spectrum and a quality testing method for a Qingfei Decoction compound preparation. In the fingerprint spectrum construction method, the chromatographic conditions include: using octadecylsilane-bonded silica gel as the packing material, acetonitrile as mobile phase A, and an aqueous solution containing phosphoric acid as mobile phase B, obtaining 10 common characteristic peaks under a specific elution program. Under the conditions of this invention, the characteristic peaks are well separated, each peak has a good peak shape, and the method can comprehensively, clearly, and effectively detect the quality of the Qingfei Decoction compound preparation.

The invention provides a compound preparation containing curcumin nano-particles as well as a preparation method and application of the compound preparation. Curcumin is wrapped by alcohol-soluble protein to form nano-particles, and the nano-particles are used as a Pickering milk solid emulsifier for emulsifying and dispersing vitamin D and olive oil into an oil phase to form a stable droplet structure; furthermore, polysaccharide with enteric characteristics is used as a water-phase carrier material, and the emulsion is encapsulated in the pellet by using a hole sharpening-solidification method, so that the solidification of the liquid medicine (the emulsion) is realized; the three natural components, namely the curcumin, the vitamin D and the olive oil, are ingeniously integrated into a whole; the targeting property of the medicine at the colon part is improved; meanwhile, the destructive effect of the gastrointestinal tract environment on the medicine carrying nanoparticles is reduced.

The invention belongs to the technical field of medicine manufacturing, and particularly relates to a compound preparation containing faropenem sodium as well as a preparation method and application of the compound preparation. According to the invention, the production prescription is optimized, the stability of the medicine can be effectively improved, the unpleasant smell of the medicine is covered, and the medication compliance of children is obviously improved. The epigallocatechin-aluminum complex can serve as a free radical scavenger in a preparation system, oxygen free radicals are effectively captured and neutralized, and the influence of oxidative stress on the medicine is reduced; moreover, the existence of aluminum ions not only enhances the stability of EGCG, but also reduces the drug degradation reaction under the catalysis of the ions through chelation with trace metal ions (such as iron, copper and the like) in the preparation. In addition, aluminum ions can also directly form a stable complex with faropenem sodium, so that the chemical stability of the faropenem sodium is further improved.

This invention discloses a quality control method for an anti-snoring oral liquid and its application, belonging to the field of traditional Chinese medicine quality testing technology. The method includes thin-layer chromatography identification of Gleditsia sinensis thorns, Scrophularia ningpoensis, and Glycyrrhiza uralensis, as well as high-performance liquid chromatography (HPLC) determination of hesperidin content. By optimizing pretreatment, developing solvent, and colorimetric conditions, this invention achieves efficient and specific identification and quantification of multiple components in the compound preparation. The method is highly specific, produces clear spots, has good separation, and is tolerant to a wide temperature and humidity range (2-40℃, 20%-75%RH), requiring no strict environmental control, significantly improving detection efficiency and providing a reliable basis for establishing quality standards for this preparation.