11 results about "Alcohol intake" patented technology

The invention belongs to the technical field of biological medicines, and relates to application of mannatide in preparation of a medicine for treating alcoholic gastric ulcer. The mannatide disclosed by the invention can be used for remarkably relieving gastric tissue hemorrhagic lesion and ulcer conditions of alcoholic gastric ulcer for the first time, and the mechanism comprises the following steps: reducing active oxygen generated by alcohol toxicity, and improving oxidative stress of a body by improving antioxidant enzyme activity of the gastric tissue; the inflammatory response of the organism is regulated by regulating and controlling an Akt / NF-kB pathway; a Bax-related apoptosis pathway is inhibited to protect gastric mucosa cells from alcohol-induced apoptosis, so that the integrity of gastric tissue mucosa is protected; the intestinal flora disorder caused by alcohol intake is regulated and controlled, and the acute alcoholic gastric ulcer is prevented by improving the intestinal flora composition of the alcoholic gastric ulcer. The application range of the mannatide is widened, and more solutions are provided for prevention or treatment of acute alcoholic gastric ulcer.

The present invention relates to the technical field of liver-protecting formula compositions, and in particular, to a liver-protecting milk thistle formula composition, and a preparation method thereof. Technical problems: the liver-protecting milk thistle formula composition, and a preparation method thereof are intended to solve the technical problems that most of existing liver-protecting compositions in the prior art are designed for the general liver protection needs of the general population and cannot specifically treat liver damage caused by excessive alcohol intake and liver diseases such as cirrhosis, acute hepatitis, hepatitis, fatty liver, cholangitis, cholelithiasis, psoriasis, and hypercholesterolemia. Technical solution: a liver-protecting milk thistle formula composition, including the following components: silymarin, puerarin, artichoke extract, glutathione, dandelion extract, and GABA. The liver-protecting formula composition has a good therapeutic effect on liver damage caused by excessive alcohol intake, and liver diseases such as cirrhosis, acute hepatitis, hepatitis, fatty liver, cholangitis, cholelithiasis, psoriasis, and hypercholesterolemia.

The present disclosure provides an information processing device, alcohol intake estimation device, method for calculating an indicator for estimating alcohol intake, alcohol intake estimation method, biological examination method, biological examination device, estimation device, learning model, estimation method, learning model generation method, and computer program. The information processing device comprises a processing unit that acquires a total heart rate change representing the total sum of heart rate changes, which are amounts by which a subject's heart rate has changed. The processing unit calculates a first indicator for estimating alcohol intake, said indicator representing the total heart rate change in a state in which the subject is inactive and a state in which the heart rate of the subject exceeds a reference heart rate.

The invention discloses a fermented sausage source active peptide as well as a preparation method and application thereof in preparation of medicines for preventing and treating alcoholic liver injury, and belongs to the technical field of biological medicines. The amino acid sequence of the fermented sausage source active peptide comprises one or more of WLKLRPILK and RGPPRPRPAPA. The method disclosed by the invention has the beneficial effects that the bioactive peptide can be efficiently extracted from the minced pork within a relatively short time. The active peptide has a remarkable relieving advantage on alcoholic liver injury, and can inhibit liver fat synthesis increase caused by alcohol intake and promote catabolism of fatty acid through an AMPK pathway. And a peptide fragment with an AMPK activation effect is rapidly screened through computer screening and molecular docking. The method has high reference value for low-cost preparation of the fermented meat-derived active peptide and prevention of alcoholic liver injury, and is suitable for popularization and application.

The invention discloses a drinking health risk assessment method based on acetaldehyde metabolism load, and relates to the technical field of health risk assessment. Comprising the following steps: selecting a key gene in an alcohol metabolic pathway, and screening known functional single nucleotide polymorphism (SNP) sites in the key gene; performing binary assignment on each selected SNP site according to the influence of the genotype of the SNP site on the acetaldehyde metabolism load; respectively calculating a liver acetaldehyde load index and a digestive tract acetaldehyde load index, and summing to obtain a total acetaldehyde load index; performing risk grading on the drinking health risk according to the total acetaldehyde load index; and analyzing the association between the alcohol intake and the disease risk by using a multivariable Cox proportional risk regression model, verifying the effect modification effect of the acetaldehyde load index, and carrying out risk stratification assessment. According to the method, the individual drinking health risk can be accurately evaluated by integrating alcohol metabolism related polygene genetic characteristics.

A lighter with an alcohol testing function comprises a shell, an end cover, an ignition unit and an alcohol testing unit. A containing cavity and an air cavity are formed in the shell, and an air blowing hole communicating the inside and outside of the air cavity is formed in the tail end of the shell. The end cover is arranged at the tail end of the shell to cover or open the blowing hole; the ignition unit is installed in the containing cavity, and the ignition end of the ignition unit extends and penetrates through the shell to the outside. The alcohol testing unit is mounted in the accommodating cavity, and the detection end of the alcohol testing unit extends into the air cavity; under the normal condition, the end cover covers the air blowing hole, and a user can normally use the ignition unit; when an alcohol test is carried out, the end cover is moved to open the air blowing hole, air is blown into the air cavity through the air blowing hole, the gas concentration in the air cavity is detected by the detection end, and the alcohol intake degree of a user can be judged; after the test is finished, the end cover covers the air blowing hole again; therefore, due to the design of the end cover, long-term exposure of the tail end of the shell can be avoided, the blow hole can be prevented from being contaminated by dirt, the use experience is improved, dust can be prevented from entering the air cavity to be attached to the detection end, and the detection precision is guaranteed.

The application discloses a nano vesicle containing quercetin and capable of protecting alcoholic liver injury, and a preparation and application thereof. Quercetin is an active component with antioxidant and anti-inflammatory effects contained in gold potted orchid, however, its in-vivo curative effect is reduced due to its low water solubility and bioavailability, and its clinical curative effect is limited. The method for obtaining quercetin by separating gold potted orchid-derived nano vesicles has the advantages of simple operation, rapidness and the like, and the lipid bilayer of the exosome-like vesicle can maintain the stability of quercetin for a long time as a natural protective film of quercetin. When acting on HepG2 cells, the gold potted orchid-derived nano vesicle can reasonably regulate the liver index of mice, effectively prevent or inhibit adverse reactions such as hepatocyte edema, fatty degeneration and lipid droplet accumulation caused by alcohol intake of the model, and has a significant curative effect on alcoholic liver disease.

The invention discloses an anti-alcoholism agent based on a polymer composite material and a preparation method of the anti-alcoholism agent, and belongs to the technical field of biomedical materials and functional foods. In order to overcome the defects that an existing hangover alleviating agent depends on metabolic enzymes, is large in individual difference and is prone to injuring the stomach and intestine, a cyclodextrin-polyacrylic acid compound and hyaluronic acid dynamic cross-linked hydrogel serve as a core, a cleanup promoting agent, natural active ingredients and functional additives are matched, and the microspheres are prepared through the processes of graft polymerization, spray drying and impregnation loading. The core mechanism is physical inclusion and adsorption of ethanol and synergy of rapid excretion promotion and liver protection in intestines, the ethanol adsorption rate is greater than 90%, the blood alcohol concentration is reduced by more than 40% in 30 minutes, and the 28-day biodegradation rate is greater than 95%. The product can be prepared into tablets, granules and other dosage forms, is suitable for social social engagement, auxiliary protection of liver functions and relieving of dizziness, nausea and other uncomfortable symptoms after alcohol intake, and has the advantages of quick action, high safety and no individual difference.

A system is provided.SOLUTION: A system comprising: means for recognizing an image of a menu of a restaurant photographed by a user and extracting a type and details of a drink; means for acquiring health data of the user and evaluating a current health condition; means for collating a past drinking history and physical condition data with the current health condition and determining an appropriate alcohol intake; and means for monitoring the health condition of the user in real time and issuing a warning when an abnormality is detected.SELECTED DRAWING: Figure 1

The invention belongs to the technical field of biological medicine, and particularly discloses a water-soluble pachymaran composition and application thereof in alcohol metabolism regulation. The mass concentration ratio of the water-soluble pachymaran to the kudzuvine root extract is 1: (1-2), the substitution degree of the water-soluble pachymaran is 0.6-0.7, the kudzuvine root extract is an ethanol extract of kudzuvine root powder, and the water-soluble pachymaran and the kudzuvine root extract play a synergistic role in regulating alcohol metabolism. On one hand, by promoting the functions of enzymes related to ethanol metabolism, the ethanol metabolism and removal efficiency is improved; on the other hand, the adverse effects of alcohol and metabolites thereof on the body are reduced by relieving inflammation and stress response accompanied by alcohol metabolism, so that a good overall effect is shown in the aspects of detoxification and alcohol metabolism regulation. The water-soluble pachymaran composition provided by the invention has the effect of improving the physiological status after alcohol intake, and has a wide application prospect in the fields of hangover alleviating and alcoholic injury protection.

This invention discloses a compound probiotic composition, its preparation method, and its applications. The compound probiotic composition comprises compound probiotics and compound compounds, wherein the components exert a synergistic effect in the body, significantly shortening the righting reflex recovery time after alcohol intake, effectively alleviating the physiological burden caused by alcohol consumption, and reducing alcohol-induced liver oxidative stress and lipid peroxidation levels. In other words, the compound probiotic composition has a hangover-relieving and liver-protecting effect. Furthermore, the compound probiotic composition helps improve and maintain the homeostasis of the gut-liver axis in alcohol- or non-alcohol-related sub-health states (such as sleep disorders), improving liver damage, regulating gut microbiota structure, and improving intestinal barrier damage. It is suitable for individuals requiring liver function regulation and nutritional intervention.