39 results about "Alcohol consumption" patented technology

This disclosure relates generally to a method and system for sensing alcohol intoxication and raising an alert. State-of-the-art methods for detecting alcohol intoxication majorly includes breath alcohol devices, bodily fluid testing, transdermal sensors, mathematical algorithms, and optical techniques. However, the impact of alcohol is not same for all but differs based on individuals' physiological traits and capacity to tolerate. Personalized systems that can sense alcohol intoxication based on individuals present alcohol consumption activity as well as the past history of consumption is not yet achieved. The proposed method of sensing the alcohol intoxication state of the subject is based on cumulative scoring technique using sensors and applications pre-installed in an GPS enabled wearable device and a mobile device. The method also triggers an alert to the subject consuming alcohol as well as to an emergency contact about altered physical and cognitive functioning under the influence of the alcohol.

The present invention provides a health risk assessment system after drinking, an electronic device and a storage medium, which relate to the technical field of data processing, wherein a data acquisition module acquires a PPG signal waveform and physiological data; a feature extraction module extracts five-dimensional time-frequency characteristic values ​​of the PPG signal waveform and physiological characteristic values ​​of the physiological data respectively; a data comparison module compares the five-dimensional time-frequency characteristic values ​​and the physiological characteristic values ​​with historical health data respectively to generate initial risk data; a drunkenness assessment module inputs the five-dimensional time-frequency characteristic values ​​into multiple decision tree sub-models in an integrated classification model to obtain multiple drunkenness degree classification results; and the drunkenness degree of a monitored object is determined according to multiple drunkenness degree classification results; and a risk assessment module generates a health risk level according to the initial risk data and the drunkenness degree. The monitored object wears an intelligent wearable device to achieve real-time monitoring, so that the monitored object can know the health risk level and avoid danger to its health due to drinking.

Disclosed are compositions for alleviation from adverse physical effects and symptoms of responsible alcohol consumption, and methods for manufacturing and / or administering the compositions. In some aspects, a composition to alleviate discomforting symptoms associated with responsible alcohol consumption includes various formulations of ginger root, L-Theanine, and / or caffeine, which may be derived from particular ingredient sources. In some embodiments, the composition(s) may optionally include salicin. In some embodiments, the composition(s) may optionally include a blend of particular vitamins, electrolytes, and / or salts.

Disclosed are compositions, devices, and methods to prevent and recover from detrimental effects of alcohol consumption, including significant undesirable symptoms of a hangover consciously felt by the alcohol consumer, as well as those that may not be consciously experienced. The present technology comprehensively targets multiple negative effects of hangovers. In one aspect, a composition includes dihydromyricetin (DHM); and N-acetyl cysteine (NAC). The composition may further include Prickly Pear Extract, Milk Thistle, Ginger Root, Vitamins B, C, and E, electrolytes, and / or sugars.

1. The name of the design product: label (alcoholic beverage). 2. The use of the design product: label for sticking on the packaging cans, boxes, bottles. 3. The design points of the design product: the combination of shape and pattern. 4. The picture or photo that best indicates the design points: perspective view. 5. The design product is a flat product, omitting the left view, right view, top view, bottom view.

The application provides a user drinking amount intervention management method and related equipment applied to the technical field of data processing. The application processes drinking purpose information of a target user and real-time physiological state information of the target user to generate a drinking training factor; processes a recent medical examination report information of the target user to generate an initial drinking amount of the target user and an initial limit drinking amount of the target user; processes identity information of the target user and the real-time physiological state information of the target user to generate a drinking amount adjustment factor; processes the initial drinking amount of the target user and the initial limit drinking amount of the target user based on the drinking amount adjustment factor to generate a target drinking amount of the target user and a target limit drinking amount of the target user; processes the target drinking amount of the target user and the target limit drinking amount of the target user based on the drinking training factor to generate drinking feedback information of the target user and processes the drinking feedback information to generate early warning threshold information.

Metabolic dysfunction–associated steatotic liver disease (MASLD), previously known as non- alcoholic fatty liver disease (NAFLD), is a condition characterized by the accumulation of fat in the liver of individuals with no alcohol consumption, and at least one cardiometabolic risk factor (overweight / obesity, high blood pressure, high blood sugar, high triglycerides levels, low HDL-C levels). The inventors demonstrated that Rab30 silencing improve metabolic dysfunction–associated steatotic liver disease (MASLD). The present invention relates to a method for the treatment of metabolic dysfunction–associated steatotic liver disease (MASLD) in a subject in need thereof comprising the administration of a therapeutically effective amount of an inhibitor of Rab30.

An alcohol consumption inference device (100) comprises a current information acquisition unit (110) that acquires, in a time series, current information which contains biological data regarding a subject being observed, a reference output unit (130) that uses the current information accumulated in a time series manner and current information at a current time to output a reference value which indicates a feature amount for a presumably sober state during a time period determined on the basis of the current information at the current time, a current state inference unit (170) that uses the reference value for the time period determined on the basis of the current information at the current time and the current information at the current time to output a feature amount for an alcohol consumption state at the current time, and an alcohol consumption state determination unit (180) that outputs, on the basis of the feature amount for the alcohol consumption state output by the current state inference unit, the result of determination regarding the alcohol consumption state of the subject being observed.

An object of a system according to an embodiment is to provide appropriate advice for preventing excessive drinking based on a health condition and a physical constitution of a drinker.SOLUTION: A system includes a constitution acquisition part, a health condition collection part, a drinking data collection part, an advice provision part, and a physical condition check part. The physical constitution acquisition unit acquires a physical constitution of a drinker to alcohol. The health condition collection unit collects a health condition of today. The drinking data collection unit collects types and amounts of alcohol to be drunk. The advice providing unit gives advice when taking the next cup. The physical condition check unit checks a physical condition in cooperation with a watch device.SELECTED DRAWING: Figure 1

The invention relates to a dihydromyricetin derivative (1,2), wherein the dihydromyricetin derivative (1,2) is edible and water-soluble and, when completely dissolved in a liquid, is unpolymerized, and to a composition containing the dihydromyricetin derivative (1,2). Furthermore, the invention relates to the use of the dihydromyricetin derivative (1,2) or the composition as an anti-hangover additive for a food and / or a pharmaceutical product for the relief, prevention, and / or treatment of hangover symptoms caused by alcohol consumption and / or for accelerating the breakdown and metabolism of alcohol.The invention further relates to a process for producing a dihydromyricetin derivative (1, 2) that is edible and water-soluble and, when completely dissolved in a liquid, is unpolymerized, comprising modifying (3) dihydromyricetin to obtain the edible, water-soluble dihydromyricetin derivative (1, 2) that, when completely dissolved in a liquid, is unpolymerized. The invention further relates to a process for maintaining the long-term solubility of the DHM derivative in aqueous solutions and preventing crystallization by adding 35-45% vol alcohol as well as essential oils or flavorings. These additional components ensure that the DHM derivative remains dissolved and stable for extended periods, making the solution suitable for use in various products such as foods, dietary supplements, and pharmaceuticals.

Disclosed are compositions for alleviation from adverse physical effects and symptoms of responsible alcohol consumption, and methods for manufacturing and / or administering the compositions. In some aspects, a composition to alleviate discomforting symptoms associated with responsible alcohol consumption includes various formulations of ginger root, L-Theanine, and / or caffeine, which may be derived from particular ingredient sources. In some embodiments, the composition(s) may optionally include salicin. In some embodiments, the composition(s) may optionally include a blend of particular vitamins, electrolytes, and / or salts.

The present invention relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who has a high drinking risk level. The present invention also relates to nalmefene for use in the reduction of alcohol consumption in a patient with alcohol dependence who maintains a high DRL after an observation period following initial assessment.

The invention discloses a method for treating waste liquid generated after glycolic acid ester is prepared from sodium glycolate in waste water, which comprises the following steps of: hydrolyzing waste liquid which is left after glycolic acid ester is extracted and contains diglycolate under an alkaline condition to obtain alcohol; and recovering the alcohol obtained by hydrolysis, and applying the alcohol to the preparation of glycolic acid ester. According to the method, the waste liquid amount is reduced, the alcohol consumption is greatly reduced, the resourceful treatment income is further increased, and the product competitiveness is improved; and meanwhile, special equipment is not needed, the process is simple, the operation is convenient, the resourceful treatment benefit of the phenoxy carboxylic acid wastewater can be greatly improved, waste is turned into wealth, the environmental protection cost is effectively reduced, and the product competitiveness is improved.

The utility model provides a volume-controllable wine cup. The volume-controllable wine cup comprises a cup body, a cup cover, a motor and a circuit board, a control switch is arranged on the outer side of the cup body, and a partition plate is arranged on the lower portion of the cup body. The cup cover is rotationally connected to a cup opening of the cup body and can cover the cup opening after being turned downwards. The motor is installed on the outer side of the upper end of the cup body and used for driving the cup cover to rotate. The circuit board is arranged in the cup body below the partition plate and is provided with a single chip microcomputer, a clock chip and a memory, the liquid level sensor is used for measuring the drinking amount of each time, the clock chip is used for timing, the single chip microcomputer is used for counting drinking amount data in unit time, the memory is used for storing data, and the control switch is used for sending a starting instruction to the single chip microcomputer after being pressed. The single-chip microcomputer starts the motor to open the cup cover when receiving the starting instruction and the drinking amount data is smaller than a preset value. According to the invention, the drinking amount in a period of time can be counted to limit excessive drinking.

The invention relates to the technical field of enzyme detection, in particular to a method for detecting enzyme activity in saliva, a method for constructing an enzyme activity-alcohol amount model and a method for predicting alcohol amount. The enzyme activity detection method comprises the following steps: S11, preparing an ethanol dehydrogenase reaction system and an acetaldehyde dehydrogenase reaction system; s12, obtaining an ethanol dehydrogenase determination group and an acetaldehyde dehydrogenase determination group; s13, obtaining an ethanol dehydrogenase blank group and an acetaldehyde dehydrogenase blank group; s14, reacting different determination groups and blank groups at the temperature of 20-40 DEG C for 1 minute; and S15, determining the absorbance of different determination groups and the corresponding blank groups at 340 nm by using a microplate reader, and calculating the enzyme activity according to the increased absorbance of the determination groups relative to the corresponding blank groups. The enzyme activity detection method disclosed by the invention is short in required time, simple to operate and suitable for large-flux sample detection, and a solution is easy to prepare.

The invention relates to an intelligent drinking monitoring method based on multi-sensor fusion, which comprises the following steps: S1, reading basic information of equipment of a cup collision opposite side through NFC (Near Field Communication) on a wine cup, and judging effective cup collision based on the information of the equipment of the opposite side and an acceleration value of a gyroscope; s2, obtaining a weight difference value of the wine glass through a pressure sensor on the wine glass, and calculating a compensation coefficient in combination with data of a temperature sensor so as to obtain an actual wine drinking amount; and S3, acquiring basic data information of the cup holder, calculating the real-time blood alcohol concentration of the cup holder, comparing the real-time blood alcohol concentration with a standard value, and performing early warning after a detection result shows that the real-time blood alcohol concentration exceeds a threshold value.

The invention discloses a deep learning-based ventilation pressure prediction method for a household sleep breathing machine. The method comprises the following steps of 1, selecting obstructive sleep apnea and hypopnea symptom influence factors; 2, determining the influence weight of each influence factor; 3, generating an original data set; 4, data standardization; 5, building a long-short term memory neural network for training; 6, verifying the model on the verification set to output an optimal model for predicting the optimal ventilation pressure; 7, real-time sleep data, including snore, drinking amount, head angle and body angle, of the patient are collected, and the data serve as input to be used for predicting the optimal ventilation pressure model; and 8, outputting a predicted optimal ventilation pressure value by using the trained model. The method has the beneficial effects that the embodiment of the invention can realize accurate dynamic pressure prediction for most people by adopting a mode of performing pressure prediction by combining the multi-sample training set with the long and short-term time network.

The invention relates to the technical field of preparation of glycine, in particular to a continuous production method of food-grade glycine, which comprises the following steps: constructing a solvent reaction system and a solvent purification system by utilizing the synergistic effect of a solvent and an anti-solvent, and matching with the contents of glycine and ammonium chloride in an ammonification reaction system and the purification system to obtain the food-grade glycine. The addition proportion and dosage of the solvent and the anti-solvent in the reaction system and the purification system are determined, auxiliary conditions such as electrodialysis, membrane separation, low temperature and the like with high energy consumption and high investment are not used, repeated refining and purification of glycine are not facilitated, and by means of the constructed reaction system and purification system, the purity of glycine is improved. The food-grade glycine can be continuously produced from an initial raw material chloroacetic acid through four steps of ammonification reaction, ammonification reaction, purification and recrystallization. The problems of high alcohol consumption in alcohol precipitation, high energy consumption in cyclic utilization of a catalyst, high production cost caused by production of high-quality glycine through repeated refining and purification and the like in the current production technology are solved.

Disclosed are compositions, devices, and methods to prevent and recover from detrimental effects of alcohol consumption, including significant undesirable symptoms of a hangover consciously felt by the alcohol consumer, as well as those that may not be consciously experienced. The present technology comprehensively targets multiple negative effects of hangovers. In one aspect, a composition includes dihydromyricetin (DHM); and N-acetyl cysteine (NAC). The composition may further include Prickly Pear Extract, Milk Thistle, Ginger Root, Vitamins B, C, and E, electrolytes, and / or sugars.

The invention belongs to the technical field of judicial expertise, aims to solve the problem that false positive is easy to occur in ethanol source judgment in the current judicial expertise, and provides an identification mark and an identification method for accurately distinguishing drinking death and post-death wine filling. The identification marks are the concentration ratio of ethanol in heart blood to vitreous humor, ethanol in lower limb muscles and testis, and EtG and EtS in the lower limb muscles and testis. Experimental basis is provided for explaining an ethanol source problem in a forensic examination process through dispersion of ethanol injected into a dead rabbit in a dead body and generation conditions of EtG and EtS. And if the concentration ratio of the ethanol in the central blood to the vitreous humor is far greater than 1 in the actual detection process, the ethanol is possibly injected after death. Therefore, in the process of a forensic examination, the concentration ratio of ethanol in muscles and testis of lower limbs and in heart blood and vitreous humor should be detected in addition to detection of EtG and EtS in the heart blood by judging whether to drink or not.

The present invention discloses a method for predicting alcohol consumption by combining curvelet transform and convolutional neural network, which belongs to the technical field of specific computing models. The method comprises: obtaining a time-feature data set based on user basic profiles, daily behavior trajectories, and purchase information results of alcohol consumption users; obtaining a plurality of curvelet coefficients based on the time-feature data set by performing curvelet transform in combination with the curvelet characteristic frequency, the plurality of curvelet coefficients including low-frequency curvelet coefficients, medium-frequency curvelet coefficients, high-frequency curvelet coefficients, and ultra-high-frequency curvelet coefficients; obtaining a plurality of feature information based on the low-frequency curvelet coefficients, medium-frequency curvelet coefficients, and high-frequency curvelet coefficients by performing feature decomposition; obtaining a plurality of convolution operation results based on the plurality of feature information by performing convolutional neural network, obtaining a pooling operation result by performing pooling operation, and obtaining an alcohol consumption prediction by performing linear correction activation.

This invention discloses a clear, stable, and low-irritant plant-based compound beverage, its preparation method, and its application. The beverage is formed by the in-situ self-assembly of polyphenol-containing plant extracts and small-molecule food-derived oligopeptides in an aqueous solution, creating nano-complex particles with an average particle size of 80–200 nm, a Zeta potential of -25 to -40 mV, and a PDI ≤ 0.3. It contains no added exogenous stabilizers, thickeners, flavoring agents, fragrances, or colorings. After 30 days of accelerated clarification at 37°C, no precipitation occurs, with a turbidity ≤ 5 NTU and a light transmittance ≥ 90%, effectively masking bitter and spicy irritations. The plant extracts are a compound of kudzu root, Japanese raisin tree fruit, chrysanthemum, poria cocos, monk fruit, ginger, and yam, with a polyphenol to oligopeptide mass ratio of 3:4. The product can relieve dry mouth and throat discomfort caused by alcohol consumption, staying up late, and smoking. The process is simple and suitable for industrial production.

The utility model relates to the field of medicine preparation devices, in particular to a water-bindered pill making machine alcohol usage amount control device and a pill making machine, the water-bindered pill making machine alcohol usage amount control device comprises a main pipeline, the main pipeline is communicated with a plurality of drip nozzles, the main pipeline is communicated with a first control valve, and each drip nozzle is communicated with a second control valve. The water-bindered pill making machine comprises the control device for the alcohol usage amount of the water-bindered pill making machine, and further comprises a machine body, a strip outlet nozzle and a pill rolling knife, the strip outlet nozzle and the pill rolling knife are arranged in the machine body, the pill rolling knife is arranged at an outlet of the strip outlet nozzle, the main pipeline and the dripping nozzle are arranged in the machine body, the dripping nozzle is arranged above the pill rolling knife and faces the pill rolling knife, and the main pipeline is connected with the main pipeline. A sensor for detecting whether medicine strips exist or not is arranged in the machine body, is arranged between the strip outlet nozzle and the pill rolling knife, and is in communication connection with the first control valve. The device has the effects of controlling the alcohol dripped from the dripping nozzle in the pelleting process and reducing the volatilization of the alcohol in the pelleting process.

The present invention relates to the field of medical technology, and in particular to a composition for relieving headaches caused by alcohol consumption and a preparation method thereof. The composition comprises the following raw materials in parts by weight: 5-10 parts of curcumin composite particles, 20-30 parts of chitosan stabilized fermentation broth, 10-15 parts of kudzu root extract, 5-10 parts of emblica fruit extract, 10-15 parts of wolfberry fruit, 5-10 parts of cassia seed, 5-10 parts of black plum, 5-10 parts of roselle extract, 10-15 parts of sweetener, and 5-8 parts of stabilizer. The curcumin composite particles are prepared by nanoliposome embedding and tannic acid and polyethylene glycol functionalization treatment, the chitosan stabilized fermentation broth is prepared by combining chitosan and red pitaya fermentation broth, and the composition is prepared by processes such as plant component extraction, mixing and blending, and sterilization treatment. The composition can accelerate ethanol metabolism, enhance liver antioxidant capacity, thereby reducing liver damage caused by alcohol, and effectively relieve headaches caused by alcohol consumption.

The utility model relates to the field of wine making systems, and discloses a retorted wine waste heat utilization system which comprises a first-stage condenser, a second-stage condenser, a first cooling circulation subsystem, a second cooling circulation subsystem and an absorption refrigeration subsystem, the first-stage condenser is used for being connected with a wine steam outlet in a wine steaming system; the second-stage condenser is connected with a wine liquid outlet of the first-stage condenser; the first cooling circulation subsystem is connected with the first-stage condenser and is used for exchanging heat with the first-stage condenser; the second cooling circulation subsystem is connected with the second-stage condenser and is used for exchanging heat with the first-stage condenser; the absorption refrigeration subsystem is connected with the first cooling circulation subsystem and the second cooling circulation subsystem; the first cooling circulation subsystem is used for providing a heat source needed by refrigeration for the absorption type refrigeration subsystem, and the absorption type refrigeration subsystem is used for providing air conditioner refrigeration and heat dissipation of the second cooling circulation subsystem. Therefore, the wine output is improved, and electric energy and water resources are saved.

This disclosure relates generally to a method and system for sensing alcohol intoxication and raising an alert. State-of-the-art methods for detecting alcohol intoxication majorly includes breath alcohol devices, bodily fluid testing, transdermal sensors, mathematical algorithms, and optical techniques. However, the impact of alcohol is not same for all but differs based on individuals' physiological traits and capacity to tolerate. Personalized systems that can sense alcohol intoxication based on individuals present alcohol consumption activity as well as the past history of consumption is not yet achieved. The proposed method of sensing the alcohol intoxication state of the subject is based on cumulative scoring technique using sensors and applications pre-installed in an GPS enabled wearable device and a mobile device. The method also triggers an alert to the subject consuming alcohol as well as to an emergency contact about altered physical and cognitive functioning under the influence of the alcohol.

This disclosure relates to methods for treating alcohol use disorder by administering to a human subject in need a therapeutically effective amount of a compound of formula (I) or a pharmaceutically acceptable salt or solvate thereof. In certain embodiments, the compound is a compound of formula (II), (IIA), (IIB), or (IIC), or a solvate thereof, and is administered in a dose of from about 0.10 mg to about 10.0 mg. The disclosure also provides methods of preventing relapse to alcohol drinking, for reducing alcohol consumption, for decreasing alcohol craving, for maintenance of alcohol abstinence, for treating or preventing withdrawal from alcohol consumption, treating alcohol-related sleep disorder, and / or for reducing stress or anxiety level in a human subject.

The invention relates to the field of medical biology, in particular to a biological preparation for inhibiting the alcohol drinking amount of an alcohol-dependent person and application of the biological preparation. The invention discloses a biological agent for inhibiting the alcohol drinking amount of an alcohol-dependent person. The biological agent is lactobacillus plantarum extracellular vesicles. The lactobacillus plantarum extracellular vesicles play a role in regulating and controlling the drinking amount of alcohol-dependent rats by regulating the expression of the BNDF, the lactobacillus plantarum extracellular vesicles can increase the expression of the BDNF of PC12 cells in an in-vitro cell culture experiment, alcohol reduces the expression of the BDNF of the PC12 cells, and the lactobacillus plantarum extracellular vesicles achieve the inhibition effect by reversing the expression of the alcohol on the BDNF of the PC12 cells. According to the biological preparation for inhibiting the alcohol drinking amount of the alcohol-dependent person and the application of the biological preparation, SD male rats serve as research objects, the inhibiting effect of extracellular vesicles derived from intestinal lactobacillus plantarum on the alcohol drinking amount of the alcohol-dependent rats and related mechanisms are researched, and a new thought is provided for clinical prevention and treatment of alcohol dependence.

This invention discloses a compound probiotic composition, its preparation method, and its applications. The compound probiotic composition comprises compound probiotics and compound compounds, wherein the components exert a synergistic effect in the body, significantly shortening the righting reflex recovery time after alcohol intake, effectively alleviating the physiological burden caused by alcohol consumption, and reducing alcohol-induced liver oxidative stress and lipid peroxidation levels. In other words, the compound probiotic composition has a hangover-relieving and liver-protecting effect. Furthermore, the compound probiotic composition helps improve and maintain the homeostasis of the gut-liver axis in alcohol- or non-alcohol-related sub-health states (such as sleep disorders), improving liver damage, regulating gut microbiota structure, and improving intestinal barrier damage. It is suitable for individuals requiring liver function regulation and nutritional intervention.