517 results about "Alcohol ethyl" patented technology

The invention discloses a novel synthetic method for 5-phenyl tetrazole, which includes the following steps: firstly performing acid neutralization to hydrazine hydrate; then adding mixing solution formed by cyanobenzene, water and ethyl alcohol to generate phenyl aminoguanidine salt; adopting sodium nitrite for diazotization to obtain nitrine amidine under the acidic condition; obtaining 5-phenyl tetrazole crude product through closed loop under the alkaline condition; obtaining 5-phenyl tetrazole acceptable product through adopting ethyl alcohol for refining. The method has the advantages of simple technology, simplicity in operation and high product yield.

The invention discloses a gradient alcohol extraction preparation method of compound honeysuckle flower drops for improving T cell activity, and relates to the technical field of traditional Chinese medicine compound preparations, honeysuckle flower and radix astragali are selected for pretreatment, an ethanol aqueous solution and an interaction regulating agent are added for infiltration, an online traditional Chinese medicine compound preparation HPLC is adopted for dynamic alcohol concentration adjustment and temperature extraction under monitoring of the traditional Chinese medicine compound preparation, the method disclosed by the invention has the advantages that the interaction regulating agent is added in the raw material infiltration stage to block bad interaction among active components, and the online monitoring system is utilized to dynamically adapt the ethanol concentration and the extraction temperature to realize step-by-step efficient dissolution of the multi-polar components; the antioxidant is matched to inhibit oxidation of thermosensitive components, and the solubilizer assists dissolution of insoluble components, so that the core defect that synergistic extraction of multi-polar active components, degradation of the thermosensitive components and interaction inhibition of the components in the compound honeysuckle flowers cannot be considered in the prior art is overcome, and loss or antagonism of the active components is effectively avoided.

The invention provides a method for analyzing the oxygen stable isotope ratio of water in a highly alcoholic beverage, and relates to the technical field of oxygen isotope analysis. The analysis method comprises the following steps: selecting at least two water samples with known oxygen isotope ratios and different values as additive water; diluting the same high-alcohol beverage to be detected by adding water to obtain a diluted sample; measuring an oxygen isotope ratio; and according to the oxygen isotope ratio of the added water and the oxygen isotope ratio of the diluted sample, calculating the oxygen isotope ratio of the water in the highly alcoholic beverage to be measured. According to the analysis method, the concentration of ethanol is reduced through dilution, so that interference of isobaric elements is avoided; and physical separation is replaced by mass conservation equation calculation, and a complex distillation device is not needed. According to the method, pretreatment is remarkably simplified, cost and errors are reduced, and rapid and accurate analysis of the water oxygen isotope in the highly alcoholic beverage is achieved.

The application provides a synthesis method of p-benzoquinone dioxime. The synthesis method comprises the following steps: (1) adding solid acid into an ethanol solution of phenol to obtain a mixed solution A, then vacuumizing and filling with inert gas; dissolving nitrite into ethanol, uniformly mixing to obtain an ethanol solution of nitrite, then vacuumizing and filling with inert gas; in an inert gas atmosphere, adding the ethanol solution of nitrite into the mixed solution A dropwise to perform nitrosation reaction, to obtain a reaction liquid B; in the inert gas atmosphere, adding an ethanol solution of hydroxylamine into the obtained reaction liquid B to perform oximation reaction; after the reaction is completed, filtering the obtained reaction liquid C, performing reduced pressure distillation on the obtained filtrate, and performing washing, filtering and drying on the obtained residual liquid of the reduced pressure distillation, to obtain p-benzoquinone dioxime. The method provided by the application reduces the occurrence of side reactions, improves the conversion rate of the reaction, and improves the yield and purity of p-benzoquinone dioxime.

The invention provides a composition for treating nerve headache and a preparation method thereof, and belongs to the technical field of medicines. The preparation method comprises the following steps: carrying out steam explosion treatment on traditional Chinese medicine powder, adding the traditional Chinese medicine powder into saline water, decocting, filtering, standing filtrate to separate out a hydrochloric acid extract, adding filter residues into ethanol, adsorbing by a magnetic adsorbent, separating by a magnet, eluting, desorbing, recovering an eluent to obtain an alcohol extract, mixing and grinding the alcohol extract, the hydrochloric acid extract and flunarizine hydrochloride / nimodipine eutectic, and filling capsules with the alcohol extract and the flunarizine hydrochloride / nimodipine eutectic. The composition for treating the nerve headache is prepared. The traditional Chinese medicine composition treats neuropathic migraine through a method of combining traditional Chinese medicine and western medicine, treats both symptoms and root causes, and is good in effect and quick and lasting in effect.

The invention relates to an ethanol upgrading device and method, the device is used for upgrading ethanol containing a small amount of ethyl acetate, the device comprises a low-pressure rectification unit, a pumping unit and a high-pressure rectification unit which are connected in sequence, a variable-pressure rectification principle is adopted, azeotrope composition is changed only through a variable-pressure mode, reasonable process parameters are matched, and the quality of ethanol is improved. The purified ethanol is extracted from the low-pressure rectification unit, and the ethanol with higher ethyl acetate content is extracted from the high-pressure rectification unit, so that a large amount of ethanol is prevented from being evaporated to the high-pressure rectification unit, the energy consumption is obviously reduced, the production cost is reduced, and the economic benefit is improved.

The present disclosure generally relates to dihydrochalcone compounds and their use for enhancing the perception of alcohol (ethanol) in food, beverages, and other comestible compositions. In certain aspects, the disclosure provides the use of such dihydrochalcone compounds to enhance an alcoholic (ethanolic) flavor of a beverage, for example, a low-alcohol or zero-alcohol beverage. In certain other aspects, the disclosure provides low-alcohol or zero-alcohol beverages containing such dihydrochalcone compounds.

This invention relates to the field of resveratrol wine production technology, and more particularly to a process for producing resveratrol wine. Specifically, by utilizing the fact that both zein and resveratrol are soluble in ethanol solution, and that their solubility increases with the increase of ethanol concentration, zein and resveratrol are processed into nanoparticles of resveratrol encapsulated in zein using an ethanol solution. After the resveratrol is made into nanoparticles encapsulated in zein, it is added to the base wine, thereby increasing the dispersion and solubility of resveratrol in the base wine. At the same time, it makes the resveratrol in the base wine more stable, which is more conducive to the long-term storage of unstable resveratrol in the wine. The resveratrol production process provided by this invention has the advantages of simple operation, improved resveratrol solubility, and improved resveratrol stability.

This invention provides a composite catalyst, its preparation method, and its application, as well as a method for the catalytic oxidation of alcohols to aldehydes, belonging to the field of organic synthesis technology. In the composite catalyst provided by this invention, elemental chromium improves the dispersibility of elemental silver on modified γ-Al₂O₃, thereby enhancing the oxidation activity of the composite catalyst for ethanol, reducing side reactions (further oxidation of aldehydes to acids or decomposition) during the catalytic oxidation of alcohols to aldehydes, and improving the selectivity, yield, and purity of aldehydes. The modified γ-Al₂O₃ has a more developed pore structure than uncalcined γ-Al₂O₃, and when used as a support, it improves the mechanical strength of the composite catalyst. Moreover, the composite catalyst provided by this invention reduces the reaction temperature and energy consumption for the catalytic oxidation of alcohols to aldehydes without affecting the alcohol conversion rate and aldehyde selectivity, thus reducing the cost of aldehyde preparation and making it more suitable for industrial use in the catalytic oxidation of alcohols to aldehydes.

The utility model relates to the field of coal ethanol, disclose a kind of rectifying device of removing isopropyl alcohol in coal ethanol, including ethanol refining A tower and ethanol refining B tower, the ethanol refining A tower is provided with A tower reflux tank and A tower reboiler, the ethanol refining B tower is provided with B tower condenser, B tower reflux tank and condensing / reboiler.The utility model in, high-purity ethanol is taken from tower side line, methanol and other light components are removed from tower top, heavy components such as isopropyl alcohol are removed from tower kettle, through A, B refining tower collaborative operation, utilize the condensation latent heat of A tower top steam to heat B tower reboiler, energy consumption reduction exceeds 40%, solve the problem that isopropyl alcohol with similar boiling point in coal ethanol is difficult to separate efficiently, significantly improve the energy economy of whole process.

The invention relates to the technical field of cork materials, in particular to SiO2-ZrO2 / cork composite particles and a preparation method and application thereof. The SiO2-ZrO2 / cork composite particles are prepared by adopting a sol-gel method, enabling SiO2-ZrO2 sol to be in full contact with and permeate into each cork particle through a vacuum impregnation process, and then forming a firm SiO2-ZrO2 layer on the surface of the cork particle after aging and freeze drying. On one hand, the ratio of silicon to zirconium is accurately controlled, the enhancement effect is maximized on the premise of avoiding particle aggregation, and the indentation damage resistance and wear resistance of the composite material are synergistically improved, and on the other hand, by regulating and controlling the volume ratio of the water-ethanol mixed solvent, the hydrolytic stability and the coating uniformity of sol are effectively improved, and the composite material has good application prospects. The bonding strength of SiO2-ZrO2 on a cork base is enhanced, the applicability of SiO2-ZrO2 to floors and wallboards is enhanced, and a reliable technical path is provided for development of high-performance environment-friendly building materials.

The utility model relates to the technical field of acetic acid ethanol preparation, in particular to a high-purity ethyl acetate refining device which comprises a base, a preparation box is fixed on one side of the top of the base, a heating copper plate is fixed at the bottom of the base through screws, a cover plate is mounted at the top of the preparation box, and a stirring assembly is mounted in the cover plate. And a recycling suction pipe is fixed to one side of the quantitative tank through a fixing rod, one end of the recycling suction pipe is in sealed connection with a piston rod assembly through threads, a three-way valve is installed at one end of the recycling suction pipe, and one side of the three-way valve communicates with a recycling pipe. According to the chemical material recycling device, chemical materials stored in the recycling suction pipe are squeezed into an original storage container through the recycling pipe by converting the outlet direction of the three-way valve, so that redundant chemical materials are recycled, the situation that the chemical materials are splashed when being recycled by experimenters is avoided, the personal safety of the experimenters is guaranteed, and the experiment efficiency is improved. Meanwhile, pollution and loss of chemical materials are reduced.

The invention discloses Leishan fish sauce sour essence as well as a preparation method and application thereof. The leishan fish sauce acid essence is prepared from ethyl acetate, absolute ethyl alcohol, ethyl isovalerate, ethyl hexanoate, isoamyl alcohol, furfuryl alcohol, ethyl lactate, ethyl caprylate, acetic acid, diethyl succinate, methyl salicylate, ethyl benzoate, ethyl laurate, hexanoic acid, phenethyl alcohol, 4-methyl guaiacol, ethyl myristate, ethyl palmitate, ethyl oleate, capsicum oleoresin, ethyl phenylacetate and ginger oil. And lactic acid, glycerol triacetate, ocimene, ethyl isovalerate, ethyl butyrate, anethole and phenylacetaldehyde. The Leishan fish sauce sour essence disclosed by the invention is soft and harmonious in overall fragrance, natural and vivid, still has stable flavor characteristics at high temperature, can make up the problem of flavor deficiency in sour soup products, realizes accurate reproduction and controllable release of composite fragrance, improves the standardization level of products, and effectively improves the preference degree of consumers.

The present invention is directed to a method for acidulation of tall oil soap in an alcohol selected from methanol, ethanol and / or iso-propanol. In the method according to the present invention, a mixture comprising sodium salts of fatty acids and rosin acids and an alcohol selected from methanol, ethanol and / or iso-propanol is acidulated using carbon dioxide.

The invention relates to an uncaria alkaloid extract as well as a preparation method and application thereof. The method comprises the following steps: heating and leaching uncaria stem and branch powder with acidic ethanol to obtain an acid alcohol leaching solution; carrying out reduced pressure distillation and concentration on the leach liquor to obtain an uncaria total alkaloid extract; removing acid-insoluble substances from the total alkaloid extract, degreasing, adjusting alkali, extracting with chloroform, and recovering a chloroform layer to obtain uncaria crude alkaloid; and dissolving the uncaria crude alkaloid in distilled water, adding into a macroporous resin chromatographic column, adsorbing, flushing, eluting by using a 20% ethanol solution with five column volumes, and collecting the eluent to obtain the uncaria alkaloid extract. The ramulus uncariae cum uncis alkaloid extract PURA1 has the effects of improving the pathological phenotype of the Alzheimer's disease model caenorhabditis elegans and improving the oxidative stress resistance of the caenorhabditis elegans, plays a role in prolonging the service life of the caenorhabditis elegans by regulating and controlling the p38MAPK signal channel of the caenorhabditis elegans, and can be used for preparing the medicine for relieving the Alzheimer's disease and resisting aging.

The invention relates to a preparation method of 3-ethoxy isoamyl propionate, and belongs to the technical field of organic solvent synthesis. The preparation method of the 3-ethoxy isoamyl propionate comprises the following steps: S1, adding ethanol, a polymerization inhibitor and a catalyst A into a reaction kettle, heating to 40-55 DEG C, then dropwise adding ethyl acrylate, preserving heat, and carrying out addition reaction for 1-3 hours to obtain a reaction mixture; s2, adding an acidic material for neutralization, and carrying out vacuum rectification to obtain ethyl 3-ethoxypropionate; s3, adding ethyl 3-ethoxypropionate and a catalyst B into a reaction kettle, heating to 100-120 DEG C, introducing isoamyl alcohol, controlling the reaction temperature to 100-115 DEG C, and carrying out transesterification for 2.5-4 hours to obtain a crude product; and S4, cooling to stop the reaction, separating to remove the catalyst B, and carrying out reduced pressure rectification on the obtained crude product to obtain the 3-ethoxypropionic acid isoamyl ester. The method has the effects of mild process, high conversion rate and high product yield.

A high specific surface area mesoporous alumina material with a surface rich in hydroxyl groups is produced by dissolving an aluminum source in an anhydrous organic alcohol solvent containing organic carboxylic acids, slowly and uniformly adding an aqueous ethanol solution to form an alumina sol, drying to obtain an alumina gel, and then treating with high-temperature steam at 400–650°C to obtain a material with... c Mesoporous alumina materials with Al2O3 crystal phase structure, well-developed mesoporous channel structure, high specific surface area and pore volume, and containing 5.0-10.0 mmol / g aluminum hydroxyl groups on the surface of mesoporous pore walls are suitable as catalyst supports for dehydrogenation reactions. The highly uniform loading of metal Pt active components significantly improves the low-temperature reaction activity, selectivity and stability of the catalyst for efficient dehydrogenation of liquid organic hydrogen supports.

The application discloses a fermented fruit juice with the effect of reducing high uric acid and a preparation method thereof, and comprises the following steps: step one, obtaining fruit wine after fruit juice fermentation, and obtaining de-alcohol fruit juice by removing alcohol from the fruit wine; step two, inoculating lactic acid bacteria into the de-alcohol fruit juice to perform lactic acid fermentation, and obtaining the fermented fruit juice; the lactic acid bacteria comprises lactobacillus helveticus CICC6064 and / or lactobacillus paracasei CICC20292. The fruit juice prepared by the fermentation process disclosed in the application not only retains the metabolic products of the yeast fermentation except for alcohol, but also increases the biomass and improves the content of apple polyphenol monomers through lactic acid bacteria fermentation, so that the fermented apple juice has the effects of rich taste and nutrition and reducing high uric acid, and has the innovation in the field of functional development of ordinary fruit juice.

The invention discloses a hexazinone preparation and a preparation method thereof, and belongs to the technical field of pesticide chemistry. The preparation method comprises the following steps: S1, preparing BC: adding BC, mixing and grinding with copper sulfate pentahydrate, putting into a tubular furnace, calcining, and cooling to obtain Cu-BC; s2, adding a modified silane coupling agent into an ethanol water solution, then adding the Cu-BC obtained in S1, stirring for 6-8 hours at 25-35 DEG C, filtering, washing and drying to obtain modified Cu-BC; s3, hexazinone is dissolved in absolute ethyl alcohol, then the modified Cu-BC is added, ultrasonic dispersion is conducted for 6-8 h, filtering, centrifugal washing and freeze-drying are conducted, and the hexazinone preparation is obtained. According to the preparation method of the hexazinone preparation, the slow release capacity of the preparation can be improved, the hexazinone utilization rate is increased, meanwhile, the preparation can be endowed with the sterilization effect, and the hexazinone preparation has wide application prospects.

The invention relates to the technical field of gene engineering, in particular to an ethanol response type gene engineering alcohol-dissolving probiotic as well as a construction method and application thereof. According to the probiotics provided by the invention, an ethanol-responsive regulation mechanism is innovatively introduced, so that the strain can specifically induce high-efficiency expression of human ethanol dehydrogenase 1B (hADH1B) and human acetaldehyde dehydrogenase 2 (hALDH2) when sensing the existence of ethanol in vivo, thereby realizing on-demand and high-efficiency decomposition of ethanol and toxic metabolite acetaldehyde thereof. Compared with continuous expression of traditional engineering bacteria, the intelligent regulation and control mode can better simulate the natural metabolic rhythm of a human body, solves the problem of bacterial metabolism, reduces the metabolic pressure of thalli while improving the hangover alleviating efficiency, and is expected to achieve a better hangover alleviating effect and higher biological safety.

The invention discloses a PDE4B-targeted siRNA liposome nano-drug as well as a preparation method and application thereof, and belongs to the technical field of biological medicines and nano-drugs. The preparation method comprises the following steps: dissolving cholesterol, DLin-MC3-DMA, DOPE and DSPE-PEG2000 in absolute ethyl alcohol to serve as an ethyl alcohol phase; dissolving siPDE4B into a sodium citrate buffer solution to serve as a water phase; then, rapidly mixing the ethanol phase and the water phase through a microfluidic device; and carrying out PBS dialysis on the obtained mixture to promote liposome assembly and remove ethanol so as to obtain the PDE4B-targeted siRNA liposome nano-drug. Compared with the prior art, the preparation process is simple, large-scale preparation can be achieved, and the prepared nano-drug has an excellent anti-pulmonary fibrosis effect, is low in toxicity, can be administrated in an inhalable mode and can effectively restrain IPF.

The application discloses a ginseng polysaccharide, a preparation method and application, and the ginseng polysaccharide is ginseng polysaccharide GP60, which is composed of glucose, galactose and arabinose, and the molar ratio of each monosaccharide is glucose: galactose: arabinose = 77.1: 16.8: 6.1; a new preparation method is adopted; after soaking and twice decocting, different proportions of 95% ethanol are added into the filtrate in batches; the obtained precipitate is added with water to prepare a solution with a relative density of 1.1 g / ml; a certain amount of the solution is taken, a certain proportion of chloroform and n-butanol is added, and a polysaccharide aqueous solution is prepared; the polysaccharide aqueous solution is added with 95% ethanol until the alcohol content reaches 60%; the solution is statically placed for 12 hours; centrifugal separation is carried out; the precipitate is collected; the collected precipitate is sequentially washed with 95% ethanol, anhydrous ethanol, isopropyl alcohol and ether; the solvent is volatilized; and the ginseng polysaccharide GP60 is obtained. The ginseng polysaccharide GP60 is non-toxic, has the effect of preventing light aging, and can be widely applied in the fields of food or health food, anti-light aging skin care products, washing and caring products and anti-light aging medicines.

The application discloses a method for separating and purifying ginsenoside F2 from fermentation liquor, and belongs to the technical field of separation and purification. The method comprises the following steps: taking the fermentation liquor from a tank, centrifuging, taking the lower precipitate, adding ethanol to stir and extract, filtering after extraction, and spin-drying the filtrate to obtain a crude product; then dissolving the crude product in an ethanol aqueous solution with a volume fraction of 10-40% to form a sample solution; then performing sample loading on YLT810 resin, and after sample loading is completed, washing impurities with an ethanol aqueous solution with a volume fraction of 45-50%, and when the liquid-phase purity of the target product reaches 70-75%, eluting with an ethanol aqueous solution with a volume fraction of 60-65%, collecting the eluate, and spin-drying to collect the solid, so that ginsenoside F2 is obtained. The method can obtain ginsenoside F2 with a purity of more than 85%, and the yield can reach more than 80%, and is suitable for industrial production.

There is provided a process of producing ethanol. The process includes processing a starch derivative-comprising slurry via a reactive process, including fermentation, with effect that at least a fermentation product, that includes ethanol, and a gaseous by-product material, that includes gaseous carbon dioxide, is produced, and processing the gaseous by-product material via a reactive process, with effect that a liquid material product, including ethanol, is produced. The concentration of ethanol, within the produced fermentation product, has a value that is at least 40% of the end of batch concentration of ethanol within the fermentation product, and no more than 95% of the end of batch concentration of ethanol within the fermentation product.

To provide a nail coating agent that contains graphene while maintaining adhesion between natural nails and nail decoration materials. [Solution] A nail coating agent comprising graphene and a solvent. A nail coating agent comprising graphene, a solvent and an antibacterial agent, wherein the solvent comprises one or more lower alcohols selected from ethanol, propanol and isopropanol and water.

The present disclosure generally relates to flavonoid compounds, such as hesperetin, and their use for enhancing the perception of alcohol (ethanol) in food, beverages, and other comestible compositions. In certain aspects, the disclosure provides the use of such flavonoid compounds to enhance an alcoholic (ethanolic) flavor of a beverage, for example, a low-alcohol or zero-alcohol beverage. In certain other aspects, the disclosure provides low-alcohol or zero-alcohol beverages containing such flavonoid compounds.

To provide a beverage to which an ethanol mouthfeel is imparted or enhanced. The method includes preparing a liquid composition having a viscosity of 1.01 mPa·s to 10 mPa·s at 20°C; obtaining a beverage from said liquid composition; obtaining the beverage comprises mixing the liquid composition with a fatty acid ester having a hydrocarbon group containing 14 or fewer carbon atoms and having an HLB value of 13.0 or greater; Beverage production method.

This invention discloses a method for preparing hollow metal sulfides based on a mild template method using calcium carbonate. Calcium chloride powder and potassium carbonate powder are uniformly dispersed separately in an alcohol solution. The two solutions are then mixed and allowed to stand for aging to obtain solution A. Simultaneously, thioacetamide is dissolved in the alcohol solution to obtain solution B, and a chloride is dissolved in the alcohol solution to obtain solution C. The chloride is either stannous chloride or copper chloride. Then, solutions B and C are added sequentially to solution A at a molar ratio of thioacetamide to chloride of 2:1 and mixed uniformly to obtain solution D. Solution D is then placed in a polytetrafluoroethylene (PTFE) reactor and reacted at 140–180°C for 12 hours. Carbon dioxide is then continuously bubbled through the reactor for 2–3 hours. The mixture is filtered and washed with water and ethanol to obtain the hollow metal sulfides. This invention can obtain hollow metal sulfides with different morphologies and avoids the contamination problems associated with high-temperature calcination or acid dissolution for template removal.

The invention discloses a method for analyzing the average hydrogen bond association strength of an ethanol water solution, which is characterized in that the average hydrogen bond association strength of the ethanol-water solution is defined as the product of the average hydrogen bond life and the average hydrogen bond number, so that the average hydrogen bond association strength of the ethanol-water solution is obtained. NMR experimental data of ethanol-water solutions with different concentrations are obtained through existing data; s2, establishing molecular dynamics initialization models of the ethanol-water solutions with different concentrations by using Packmol; s3, acquiring parameters for calculating the hydrogen bond association strength of the model by using Gromacs software, and calculating the hydrogen bond association strength; s4, drawing a comparison graph of the experimental data and the calculation data through Origin; s5, changing concentration and temperature parameters, and verifying the reasonability of the model; and S6, verifying the universality of a theoretical calculation result through an interface phase model. The average hydrogen bond strength is calculated through simulation, the evaluation time is shortened, the evaluation efficiency is improved, and the evaluation cost is reduced.

The object of the present invention is to provide an alcohol composition that contains hydroxypropyl methylcellulose or methylcellulose in a manner that allows the thickening properties of hydroxypropyl methylcellulose or methylcellulose to be exerted, thereby not only having a viscosity that is easy to spread and does not drip easily, but also suppressing liquid dripping and / or improving transparency, and having a good spreadability. The above object is achieved by an alcohol composition comprising: 60 to 93 parts by mass of at least one alcohol selected from ethanol and isopropanol; 3.0 to 39.9 parts by mass of water; and 0.1 to 4 parts by mass of at least one water-soluble cellulose ether selected from hydroxypropyl methylcellulose and methylcellulose, wherein the loss tangent (tanδ) of the alcohol composition, measured at 20°C, a frequency of 1 Hz, and a deformation of 0.1%, is 0.10 to 1.00.