A compound of formula (IV): O is a
solid support; L is a linking group or a
single bond; X′ is selected from CO, NH, S, or O; A is O, S, NH, or a
single bond; R2 and R3 are independently selected from: H, R, OH, OR, ═O, ═CH—R, ═CH2, CH2—CO2R, CH2—CO2H, CH2—SO2R, O—SO2R, CO2R, COR, CN and there is optionally a
double bond between C1 and C2 or C2 and C3; R6, R7, and R9 are independently selected from H, R, OH, OR, halo, nitro, amino, Me3Sn; R11 is either H or R; Q is S, O or NH; R10 is a
nitrogen protecting group; and Y is a
divalent group such that HY═R, and other related compounds and collections of compounds.