2033results about "Ion sources/guns" patented technology

Systems and methods are described for collecting and combining multiple scan samples from a surface of a semiconducting wafer. A system embodiment includes, but is not limited to, a scan nozzle configured to introduce a first scan solution to a surface of a semiconducting wafer to remove impurities from the surface to provide a first scan sample and retrieve the first scan sample, the scan nozzle further configured to introduce a second scan solution to the surface of the semiconducting wafer to remove residual impurities from the surface to provide a second scan sample and retrieve the second scan sample; and a collection vessel in fluid communication with the scan nozzle, the collection vessel configured to receive each of the first scan sample and the second scan sample from the nozzle and to mix the first scan sample with the second scan sample to provide a combined scan sample.

A gas analyzer apparatus includes: a sample chamber that is provided with a dielectric wall structure and into which a sample gas to be measured flows; a plasma generation mechanism for generating plasma inside the sample chamber, which has been depressurized, using an electric field and / or a magnetic field through the dielectric wall structure; a gas input apparatus configured to cause only the sample gas to flow from a process into the sample chamber; a first detector configured to detect components in the plasma by filtered ionized gas from the generated plasma; and a second detector configured to analyze light emission of ions in the plasma inside the sample chamber and output a second detection result that is to be synchronized with the first detection result of the first detector.

ICP-MS includes: an ion source to ionize a sample component; a vacuum chamber (4-into which generated ions are introduced; a cell inside the vacuum chamber to bring the ions into contact with a predetermined gas; a mass spectrometer unit at a later stage of the vacuum chamber to perform mass spectrometry of ions having passed through the cell or ions derived from the ions; a first gas introduction unit to introduce a predetermined gas into the cell; a second gas introduction unit to introduce a predetermined gas into the vacuum chamber and outside the cell; and controllers to control gas introduction such that a gas is introduced by the first gas introduction unit when analysis is performed while bringing a gas into contact with ions, whereas a gas is introduced by the second gas introduction unit when analysis is performed without bringing a gas into contact with ions.

A method of detecting one or more PFAS in a sample of animal tissue, comprising: spraying electrically charged solvent droplets onto the sample of animal tissue so as to generate analyte ions from analyte in the animal tissue; passing the analyte ions into a mass spectrometer; and mass analysing the analyte ions so as to determine if the one or more PFAS is in the animal tissue.

The invention belongs to the technical field of isotope detection, and particularly relates to a plutonium isotope accelerator mass spectrometry measuring device based on positive ion ionization, which comprises a positive ion source for ionizing plutonium isotope to generate positive ions, the positive monovalent ions of the plutonium isotope accelerated by the accelerating tube enter the stripping system and then are stripped into multi-charge state positive ions, 3 + charge state plutonium isotope ions are selected by the analysis magnet for analysis, and after interference of various analysis fragments is eliminated by the electrostatic analyzer, the 3 + charge state plutonium isotope ions are measured by the detector. The ionization efficiency of the plutonium isotope is improved, the sample preparation process is simplified, and the in-situ analysis of the sample can be realized.

The invention relates to the technical field of instruments and meters, in particular to an inductively coupled plasma mass spectrometer system for intelligent data processing and report generation. Comprising a sample introduction unit, a plasma excitation and ionization unit, a mass analyzer and detection unit, a vacuum system unit and an intelligent data processing and report generation unit. Efficient ionization is achieved through a bipolar radio frequency switching and AI optimized reaction gas plasma source, the AI optimization module monitors in real time and dynamically adjusts parameters so that the ionization efficiency can be stabilized at 92% + / -2%, and meanwhile a reaction gas control system can optimize plasma conditions to suppress interference ions. And the mass analyzer and the detection unit realize high-precision ion separation by utilizing AI interference correction and a QMS-TOF double analyzer mode, and an interference elimination module can automatically eliminate polyatomic ion interference, so that the ionization efficiency, the analysis precision and the accuracy are improved, the interference is effectively inhibited, and the analysis capability of the system on a complex sample is enhanced.

The invention provides a trapped ion mobility separator (TIMS) and methods to operate it wherein an ion region of the TIMS, through which ions travel along an axis from an entrance to an exit, has an elongate cross-sectional profile perpendicular to the axis with a long dimension and a short dimension. First and second counteracting forces on the ions along the axis are provided, wherein at least one of the first and second forces has an effect on the ions that is ion mobility dependent, and wherein at least one of the first and second forces varies spatially along the axis such that ions are trapped and separated by ion mobility. Different embodiments provide the first and second forces using different combinations of gas flow and electric field potential, and employ various electrode structures that provide the system with different advantageous characteristics.

The invention discloses a three-dimensional laser post-ionization-secondary neutron particle mass spectrometer which comprises a vacuum pool, a sample introduction system, a primary ion emission system, a three-dimensional laser post-ionization system, an ion optical system, a time-of-flight mass spectrometer, an observation system and a computer control system. By adjusting the wavelength, the frequency and the energy value of the laser, resonance between the energy of laser photons and the electron energy level of target molecules can be realized to realize selective ionization of substances, and the method has extremely high element, nuclide and molecule selectivity, can provide the sensitivity of an instrument, and can be used for mass spectrometry. The device can be applied to single-cell imaging analysis test of lipid, metabolites, small-molecule drugs and part of elements with the molecular weight smaller than 1000 Da, the problems of space metabolome small-molecule metabolite test and ultrahigh spatial resolution imaging are solved, and the device can be independently used as an SIMS when laser post-ionization is not used.

The invention discloses a discharge ionization source for an ion mobility spectrometry. The discharge ionization source is designed by adopting a low-temperature plasma discharge principle. A radio frequency electrode of the discharge ionization source is a rod-shaped metal electrode arranged in an inner cavity of the single-end-opened quartz glass tube, direct-current electrodes of the discharge ionization source are arranged on the outer wall face of the discharge glass tube body in an array mode at equal intervals, the potential of each direct-current electrode can be independently adjusted, and the direction of a direct-current electric field in the ionization source can be conveniently adjusted and controlled. The migration direction of the ions is further controlled; in addition, a plurality of gas interfaces are arranged on the quartz glass tube, so that the gas flow direction in the quartz glass tube and the components of the discharge gas can be regulated and controlled. Based on the structural design of the array type direct current discharge electrode and the multi-gas interface, the discharge ionization source takes air as discharge gas, can realize positive and negative ion mode switching, reaction reagent ion component switching and sample ionization mode switching, and is simple in structure, convenient to operate and suitable for the ion mobility spectrometer.

A machine, article, process of using, process of making, products produced thereby and necessary intermediates. Illustratively, there can be a process that includes: ionizing at least some injected gas to form ions; confining, without using magnetic fields, at least some of said ions to produce confined ions; accumulating at least some of said confined ions to produce accumulated ions; cooling at least some of said accumulated ions to produce cooled ions; compressing, without using magnetic fields, at least some of said accumulated ions to produce compressed ions; accelerating at least some of said compressed ions to produce accelerated ions; ejecting at least some of said accelerated ions; and measuring at least one property of said ejected ions.

A mass spectrometer includes an ion source unit including: a housing; a cover accommodating the housing; an enclosure accommodating the cover; a probe passing through the cover and the housing to nebulize a liquid sample into the housing; a heated gas nozzle including a main body portion being hollow and located between the cover and the housing to discharge a gas heated by a heater in the main body portion into the housing; enclosure intake and exhaust ports; cover intake and exhaust ports; a first exhaust fan to discharge air flowing from the cover intake port and passing through the cover through the cover exhaust port; and a second exhaust fan to discharge air discharged into the enclosure from the cover exhaust port and air flowing from the enclosure intake port and passing through the enclosure, to an outside through the enclosure exhaust port.

A hybrid inductively coupled plasma mass spectrometer (ICP-MS) system is disclosed for simultaneous elemental and molecular analysis in positive and negative polarities. It includes an ICP torch that generates plasma with a buffer gas, producing both positively and negatively charged ions from a sample. Positioned between the sampler and skimmer, an insert with a defined geometry forms a reaction chamber. Various embodiments feature multiple apertures for pressure control, a rotatable disk for aperture regulation, a slider gate for pressure adjustment, a circular gate with adjustable radial apertures, and an inlet for introducing gases, reagents, dopants, or analytes. These components enable precise pressure modulation, optimizing performance for dual-polarity mass spectrometry. The system enhances analytical flexibility by facilitating controlled ion reactions, improving sensitivity and specificity for both elemental and molecular applications. This innovation expands ICP-MS functionality, supporting diverse scientific and industrial applications requiring high-precision mass analysis.

The present invention discloses a method for analyzing sources of Cd / Pb combined polluted farmland soil using bimetallic isotopes (Cd—Pb), comprising the following steps: collecting respectively a soil sample and risk source samples through a sample collection device; determining respectively Cd isotope ratio and Pb isotope ratio of the soil sample and the risk source samples; plotting by using the Cd isotope ratio and the Pb isotope ratio of the soil sample and the risk source samples as coordinates, to obtain a projection plot of the isotope ratios; recognizing a pollution end-member polluting farmland soil through the projection plot of the isotope ratios to obtain a recognition result for the pollution end-member, and then confirming the pollution end-member; and calculating a relative contribution rate of the pollution end-member, to obtain an analysis result for the source of isotopes. The present invention uses the two metal isotopes of Cd—Pb to mutually restrict and confirm each other to solve the problem of poor analytical accuracy caused by similar or overlapping isotope values of samples and isotope fractionation, and realizes accurate recognition and quantitative analysis for the source of heavy metals Cd / Pb pollution of farmland soil.

The invention belongs to the technical field of online analysis of organic pollutants, and particularly relates to a device and a method for real-time online analysis of non-volatile organic pollutants. The device comprises a sample injection module, a vacuum ultraviolet lamp, an ionization source cavity, a repulsion electrode, an ion funnel, a mass analyzer and a vacuumizing module, the ionization source cavity is provided with a sample injection port, a vacuum extraction port and an ion output port, and the vacuum ultraviolet lamp, the repulsion electrode and the ion funnel are sequentially arranged in the ionization source cavity at intervals in the axis direction of the ion output port; the ion funnel is close to the ion output port; the sample injection module is arranged at the sample injection port; the vacuumizing module is arranged on the vacuum extraction opening; the ion output port is externally connected with a mass analyzer; a direct-current voltage is applied to the repulsion electrode, and a direct-current voltage and a radio-frequency voltage are applied to the ion funnel. According to the invention, the ions with relatively large initial distribution area can be focused, so that the detection sensitivity is further improved, and the detection requirements on trace non-volatile organic pollutants are met.

In order to improve the ionization efficiency and ion collection efficiency in an ESI ion source to achieve a higher level of analysis sensitivity while improving the throughput of the analysis, one mode of the present invention provides an ion analyzer equipped with an ion source employing an electrospray ionization method, where the ion source (2) includes: a plurality of capillaries (211-218) configured to spray a supplied liquid sample in the same direction; one or more auxiliary electrodes (23, 231-328) arranged so as to be surrounded by the plurality of capillaries; and a voltage supplier (24) configured to apply, to the plurality of capillaries, a DC high voltage for which the potential of the one or more auxiliary electrodes is used as a reference.

An electron impact ion source includes: a first ionization region including an aperture configured to receive a first molecule into the first ionization region, the first ionization region configured to receive an electron beam along a first axis to generate a first ion beam from the first molecule along the first axis; and a second separate ionization region including an inlet configured to receive a second molecule into the second ionization region, the second ionization region configured to receive the electron beam along the first axis to generate a second ion beam from the second molecule along the first axis.

The present disclosure pertains to method and system of characterizing a protein using an electrospray ionization source.

Improvements in acoustically dispensed samples that are injected into an open port probe (OPP) are described. Apparatus and method are described that calibrate the volume dispensing determination and mechanisms in the acoustic dispenser to produce accurate and precise volumetric delivery.

The invention discloses a composite ion source device for coupling atmospheric pressure interface orbitrap mass spectrometry, which belongs to the field of mass spectrometry detection and comprises a photo ionization / photo-induced association ionization ionization and ion transmission mechanism, a gas sample introduction mechanism, a high-flux radio frequency vacuum ultraviolet light source mechanism and an ion source and mass spectrometry interface mechanism. By adopting the composite ion source device for coupling the atmospheric pressure interface orbitrap mass spectrum, organic components with different polarities, ionization energy and ion affinity in a complex mixture can be efficiently ionized, and through reasonable structural design, the organic components are coupled with the high-resolution orbitrap mass spectrum with the atmospheric pressure interface, so that the high-resolution orbitrap mass spectrum is obtained. The detection range of complex organic components is widened, and the resolution capability and the detection sensitivity of low-abundance or high-molecular-weight organic components are improved.

The invention discloses a thermal desorption sample injection ion source with a separation function, which comprises an ionization cavity, and the top end of the ionization cavity is detachably connected with a heat insulation pad; the heating cavity is fixed to the top end of the heat insulation pad, and a mounting base is mounted at the bottom in the heating cavity; according to the sample injection system, a heating cavity comprises a sample injection unit installed at the top end of the heating cavity, a sample injection pipe is fixedly connected to an installation base, and the sample injection unit is communicated with the sample injection pipe through a sample separation column; the heating system is mounted on the mounting seat; the ionization unit is vertically fixed on one side wall of the ionization cavity, and the ionization unit and the sample feeding pipe are vertically arranged; the detection unit is vertically and fixedly connected to the other side wall of the ionization cavity; a waste liquid opening is formed in the bottom of the ionization cavity. According to the invention, the ionization competition of the target compound of the atmospheric pressure ionization source can be greatly reduced, the sensitivity and the quantitative stability are improved, and more accurate rapid detection is realized.

The invention discloses a sampling device for ICP-MS (Inductively Coupled Plasma Mass Spectrometry) in the technical field of instrumental analysis. The sampling device comprises a liquid inlet mechanism and an atomization mechanism, the liquid inlet mechanism is used for inputting a liquid sample into the atomization mechanism, the atomization mechanism comprises a concentric atomizer and an atomization chamber, the concentric atomizer is communicated with the atomization chamber, and the atomization chamber is communicated with a waste liquid barrel and an ICP torch pipe; a self-cleaning mechanism is arranged on a communication path of the concentric atomizer and the atomizing chamber, the self-cleaning mechanism comprises a movable cylinder, the movable cylinder is rotationally connected into a nozzle of the concentric atomizer, contact electrodes are symmetrically arranged in the movable cylinder, and when the movable cylinder is blocked, the contact electrodes form a path; the contact electrode is electrically connected with a torsion mechanism and a reverse blowing mechanism, the torsion mechanism is used for twisting the movable cylinder when the contact electrode forms a path, and the reverse blowing mechanism is used for intercepting carrier gas input into the concentric atomizer and reversely blowing the carrier gas out of a nozzle of the concentric atomizer. According to the invention, self-cleaning can be carried out when blockage occurs in the sample introduction process, and sample analysis interruption caused by blockage is reduced.

The invention relates to a femtosecond laser-assisted chemical ionization method for mass spectrometry of organic molecules. According to the method, high-concentration primary reagent ions are provided for subsequent chemical ionization by femtosecond laser ionization; high-concentration charges carried by primary reagent ions are transferred to a low-concentration to-be-analyzed sample by chemical ionization, the ionization volume of femtosecond laser ionization is equivalently enlarged, and meanwhile, the soft ionization characteristic of two ionization methods is maintained, so that the high-concentration to-be-analyzed sample can be analyzed under the condition of an open or closed air chamber. And carrying out ultrahigh-sensitivity mass spectrometry on the to-be-analyzed sample. The method is combined with a desorption technology or a liquid sample gas distribution device, and can be expanded to analysis of gas, solid and liquid samples; the device is compatible with wide air pressure conditions and can be applied to closed air chamber or open detection environment; the universality and soft ionization characteristics of femtosecond laser ionization and chemical ionization are reserved, and an ionization method with universality and ultrahigh sensitivity is provided for mass spectrometric detection of organic molecules.

The invention provides an in-situ pyrolysis device adopting a glow ionization source. The in-situ pyrolysis device comprises a high-temperature pyrolysis device, a glow ionization device, a two-stage sampling cone, a quadrupole rod device and a flight time mass analyzer, the high-temperature pyrolysis device comprises a first copper block, a second copper block, a graphite sleeve and a long graphite pipe; the glow ionization device comprises a first electrode fixing cylinder, a second electrode fixing cylinder and an annular electrode; the two-stage sampling cone is divided into a first-stage sampling cone and a second-stage sampling cone; and the quadrupole rod device comprises four quadrupole rod electrodes which are parallel to one another and are symmetrically arranged. Pyrolysis reactants generate fullerene and intermediate products thereof through a high-temperature pyrolysis device, then product molecules are ionized through a glow ionization device, ionized ions pass through a two-stage sampling cone and are guided by a radio-frequency electric field and a direct-current electric field of a quadrupole rod device to reach a time-of-flight mass analyzer for in-situ mass spectrometric analysis, and the mass spectrometric analysis result is obtained. In-situ mass spectrometry analysis of'first ionization and second sampling 'can be realized, and fullerene and intermediates thereof formed by high-temperature pyrolysis can be captured.

A position control system may obtain image data representing one or more images depicting an inlet of a mass spectrometer and an emitter positioned near the inlet, and adjust a position of the emitter relative to the inlet to an optimal position at or near a reference position relative to the inlet based on the image data.

The invention relates to the technical field of vacuum equipment, and discloses an ion lens assembly, an ion source, a mass spectrometer and a mass spectrometry system. The ion lens assembly includes a deflection lens assembly and a return lens assembly. The deflection lens assembly is used for focusing an ion beam in the incident particle beam and enabling the ion beam to deflect towards a first direction. And the axis-returning lens assembly is used for receiving the ion beam from the deflection lens assembly, and the axis-returning lens assembly is used for focusing the received ion beam and enabling the ion beam to deflect towards a second direction.

The invention belongs to the technical field of mass spectrum ionization sources, provides an online detection mass spectrum ionization source for gas components at an outlet of a combustion chamber of an aero-engine, and solves the problem that an existing ionization source is difficult to be applied to a field test for measuring the concentration of components at the outlet of a combustion chamber of a real aero-engine. According to the technical scheme, the device comprises an ionization source cavity and a radio frequency windowless discharge lamp, a plate electrode, a taper hole electrode, a lamp holder electrode, a direct current transmission electrode, a radio frequency transmission electrode and a differential electrode are sequentially arranged in the ionization source cavity in the axis direction, and a discharge gas inlet is formed in the ionization source cavity. One end of the radio frequency windowless discharge lamp is connected to the discharge gas inlet, and the other end of the radio frequency windowless discharge lamp extends into the lamp holder electrode; the taper hole electrode enables fuel gas to be fed in a molecular beam mode, efficient transmission of stable components and active components in the fuel gas is guaranteed, efficient transmission of ions is achieved in the mode that the direct-current transmission electrode and the radio-frequency transmission electrode are combined, and full-spectrum online analysis of the components of the fuel gas at the outlet of a combustion chamber of an aero-engine can be achieved.

A method and corresponding devices to reduce the presence of unwanted ions within the pseudo-potential well of the RF fields for inductively coupled plasma mass spectrometry is disclosed. This method reduces space-charge effects and leaves more room available for the ions of interest and, hence, leads to increased transmission of the desired ions into the mass analyzer. In the present invention, the space charge is reduced by adding a low-band resolving DC potential, or a fast sweeping resolving DC potential with a notch, or a fast constant resolving DC potential with a notch, or by adding auxiliary quadrupolar or dipolar RF potential to the quadrupole ion guide, such that all the unwanted ions will be outside the stable region and therefore ejected. This reduces the charge density in the ion beam and ameliorate space charge effects.

The present invention relates to the field of analytical chemistry, and discloses a mass spectrum ionization element for macrolide antibiotic detection and a preparation method thereof, the mass spectrum ionization element comprises: a conductive substrate made of stainless steel; the adsorption layer is attached to at least part of the surface of the substrate, the adsorption layer is formed by a boric acid functionalized covalent organic framework, and the boric acid functionalized covalent organic framework is of a polycyclic structure composed of repeated units shown in the formula I in the specification. The mass spectrum ionization element is uniform in coating, high in selectivity on macrolide enriched antibiotics in a complex matrix and high in enrichment capacity, an eluent of the mass spectrum ionization element can be used for detection based on a liquid chromatography method and can also serve as a mass spectrum ion source solid substrate, mass spectrum detection is conducted through electrospray ionization, the detection steps are simple, and the mass spectrum ionization element is suitable for mass spectrum detection. And the detected background noise is low.

The invention provides a reactor and a dual-light-source mass spectrum device for in-situ detection of gas-phase species in a catalytic reaction. The reactor comprises a control part, a first tube body and a second tube body, the control part comprises a first shell and a switching piece; the first shell is provided with a first channel and a second channel which are arranged in the first direction. The switching piece is arranged between the first channel and the second channel; the first pipe body extends in the first direction and is located on the side, away from the second channel, of the switching piece. The first pipe body is communicated with the first channel; the second pipe body extends in the first direction and is partially located in the second channel. The second pipe body is connected with the first shell and can move in the first direction relative to the first shell. The switching piece moves relative to the first shell to control connection and disconnection of the first channel and the second channel. When the first channel communicates with the second channel, the second pipe body is allowed to partially extend into the second pipe body, and when the first channel is isolated from the second channel, the second pipe body is located on the side, away from the first channel, of the switching piece. The application of the reactor realizes material replacement on the premise of not breaking vacuum.

A system and method for determining a net source rock thickness is disclosed. The method includes obtaining at least one well log, a first and second plurality of core samples from a wellbore, and for each of the first plurality determining a relative abundance of inorganic materials, and for each of the second plurality a set of organic material data. The method further includes determining a validated total organic content and a measured source rock thickness based on the organic material data and relative abundance of inorganic materials and determining a data and a prediction portion of the wellbore, based on the second plurality sample locations. The method still further includes determining a cut-off value for each well log, predicting a source rock thickness from the cut-off values and the net source rock thickness from a sum of the predicted and the measured source rock thicknesses.