63results about "Spectrometer circuit arrangements" patented technology

An ion guide or ion trap that comprises a plurality of electrodes (102) is disclosed. The ion guide or ion trap includes a detector (205) that can detect light or particles (114) emitted from the ion guide or ion trap due to electrical breakdown, and a control circuit (111) that can control the ion guide or ion trap in response to the detector (205) detecting light or particles (114) emitted from the ion guide or ion trap.

The invention relates to the technical field of analysis instrument ionization sources, in particular to a VUV lamp ionization source device with efficient heat dissipation capacity. The device comprises a VUV lamp, a heat dissipation unit, a VUV lamp driving electrode, a driving circuit and an ion guide focusing unit. The heat dissipation unit carries out cooperative heat dissipation on the VUV lamp and the pulse transformer through a fan, and the problems of signal attenuation and device aging caused by temperature rise are solved. The driving electrode adopts a pairwise pairing structure of upper and lower and left and right electrode pairs to form an inclined electric field to prevent ions from bombarding the lamp wall and the light window; the drive circuit is a half-bridge or full-bridge topology, can adjust the pulse frequency and the power supply voltage, and achieves the switching between a high-voltage low-frequency mode and a low-voltage high-frequency mode. The ion guide focusing unit efficiently leads out and separates ions through cooperation of a conical focusing electric field and a conductive film forward electric field. Through four-dimensional innovation of heat dissipation, electrodes, driving and transmission, the stability, the service life and the detection sensitivity of the device are improved, and the device is suitable for analytical instruments such as ion mobility spectrometry and mass spectrometry.

A miniature electrode apparatus is disclosed for trapping charged particles, the apparatus includes, along a longitudinal direction, a first end cap electrode, a central electrode having an aperture, and a second end cap electrode. The aperture is elongated in the lateral plane and extends through the central electrode along the longitudinal direction and the central electrode surrounds the aperture in a lateral plane perpendicular to the longitudinal direction to define a transverse cavity for trapping charged particles. Electric fields can be applied in a y-direction of the lateral plane across one or more planes perpendicular to the longitudinal axis to translocate and / or manipulate ion trajectories.

Methods and apparatuses for ion peak compression and increasing resolution of ions are disclosed. Packets of ions are introduced into a device. A first electric field is applied for dispersing the ion packets temporally or spatially according to their mobilities A second intermittent traveling wave is applied for regrouping or merging the dispersed ion packets into a lesser number of trapping regions with narrower peaks. The ions packets are compressed into the narrower peak regions by varying a duty cycle of the intermittent traveling wave.

A radio frequency (RF) choke for use within a mass spectrometer comprises a bobbin having a hollow channel, a plurality of wire windings wound around the bobbin, each of the wire windings presenting a lattice winding pattern having a number of crossovers per turn of from about 1 to about 4, and a magnetic core disposed within the hollow channel of the bobbin. The RF choke exhibits an impedance in the range of from about 15 M ohms to about 150 M ohms with respect to an RF frequency generated by an RF voltage source within the range of from about 500 KHz to about 3 MHz, and a power dissipation equal to, or less than, about 3 W with respect to a peak-to-peak RF voltage of an RF voltage source of at least about 1 kV.

A power supply system 1 for a mass spectrometer. The system comprises a positive voltage supply and negative voltage supply, and first and second optocouplers 19, 20 which are controlled by a controll

The invention provides an ion optical system high-voltage power supply for a mass spectrometer, and relates to the technical field of high-voltage power supplies, and the ion optical system high-voltage power supply for the mass spectrometer comprises a high-voltage input module of which the output end is connected with the first input end of a modulation circuit so as to provide a first input voltage for the modulation circuit; the input end of the low-voltage input module is in communication connection with the output end of the mass spectrometer, and the output end of the low-voltage input module is connected with the second input end of the modulation circuit so as to provide second input voltage for the modulation circuit; and the output end of the modulation circuit is connected with the input end of the mass spectrometer so as to modulate the second input voltage to obtain a target voltage. According to the ion optical system high-voltage power supply for the mass spectrometer, the low-voltage control signal is modulated into the target voltage through efficient communication with the control system of the mass spectrometer, and the diversified voltage requirements of the ion optical system of the mass spectrometer in different working modes are met.

A quadrupole mass filter array consists of five quadrupole segments. An input quadrupole segment is configured to receive RF voltages. A secondary quadrupole segment is located downstream of the input quadrupole segment and is configured to receive RF and high-resolution DC voltages. A middle quadrupole segment is located downstream of the secondary quadrupole segment and is configured to receive RF voltages. A primary quadrupole segment is located downstream of the middle quadrupole segment and is configured to receive RF and high-resolution DC voltages. An end quadrupole segment is located downstream of the primary quadrupole segment and is configured to receive RF voltages.

A high-voltage (HV) power supply device outputs an output voltage based on a control signal generated by dual analog / digital feedback loops. The control signal is determined at least in part by an error amplifier that receives a measurement signal attenuated proportionally to the output voltage and an output signal from a digital-to-analog converter (DAC). The ADC also receives the measurement signal and transmits it in digitized form to a digital processor. The digital processor calculates a digital DAC data signal based on the measurement signal and a digital setpoint input signal corresponding to a setpoint voltage value desired to be output from the high-voltage source. The DAC receives the DAC data signal and converts it into a DAC output signal that is transmitted to the error amplifier.

The performance of a power supply module is to be improved. The occurrence of discharge in the power supply module is to be prevented, and the size of the power supply module is to be reduced. In a power supply module, substrates are provided being stacked in a planar view. A low voltage circuit and a high voltage circuit are formed on a first substrate such that a distance is kept for preventing surface discharge, and a low voltage circuit is formed on a second substrate. A distance between a component of a high voltage alternating current circuit on the high voltage circuit and a component of the low voltage circuit is three times a shortest distance, at which space discharge does not occurs, between a component that constitutes a high voltage direct current circuit on the high voltage circuit and a component that constitutes the low voltage circuit.

In a TOFMS measurement unit, an ion acceleration section accelerates ions to send them into a flight space, within which a flight-field creation section creates, an electric field for causing ions to fly. A controller unit operates the measurement unit so as to repeat a measurement for a predetermined sample while varying a voltage applied to an electrode in the measurement unit, and calculates mass-resolving power based on each measurement result. An approximate function calculator unit finds an approximate function representing a relationship between the voltage and the mass-resolving power, based on data of combinations of the voltage and the mass-resolving power obtained under the control of the controller unit. A voltage determiner unit determines a voltage value corresponding to a target value of the mass-resolving power by the approximate function, and determines the voltage value as a voltage to be applied to the electrode in the TOFMS concerned.

The gas analyzer (1) comprises a sample chamber (40) into which a sample gas (9) to be measured flows, a plasma generation circuit (10) that generates plasma (8) in the sample chamber (40), and an analyzer 30 that analyzes the sample gas via the plasma (8) generated in the sample chamber. The plasma generation circuit (10) includes a plasma induction circuit (13) and an RF power supply circuit (11) configured to supply RF power to the plasma induction circuit. The plasma induction circuit is directly incorporated as at least part of the resonant components of the RF power supply circuit.

A mass spectrometer system (10) is provided in which the voltage controller (12) can have separate first and second high-voltage control circuits (34, 40) which are physically disconnected from and at different ground planes to one another. Communication between the first and second high-voltage control circuits (34, 40) is enabled via an interface circuit (30) and one or more wireless, preferably radio- frequency, communicators (38, 44, 46, 48).

To provide an amplifier circuit that can be suppressed in heat generation and increases in size, and furthermore can materialize high frequency operation and high power.SOLUTION: An amplifier circuit 101 comprises a first current source circuit 113 that outputs a current having a predetermined amount of a current to a first wiring L1, a voltage amplifier circuit 110 that amplifies the voltage of an input signal, a first level shift circuit 111 that is connected between the first wiring L1 and the output of the voltage amplifier circuit 110 and shifts the voltage of the signal output from the voltage amplifier circuit 110, a first voltage follower 117 that is connected to the first wiring L1 and amplifies the signal in the first wiring L1, and a first capacitor 210 that is connected between the first wiring L1 and the output of the voltage amplifier circuit 110.SELECTED DRAWING: Figure 1

An ion detection current conversion circuit includes: a conversion amplifier coupled to a conversion resistor assembly to convert an ion detection current generated by an ion detector into an ion detection voltage, the conversion resistor assembly including a resistor with high resistance and a capacitor compensation element; and a compensation voltage circuit for obtaining a compensation voltage from the ion detection voltage and feeding the compensation voltage to the capacitor compensation element, the compensation voltage circuit including a variable resistor for adjusting the compensation voltage. The conversion circuit may further include: a voltage reduction circuit for obtaining a reduced voltage from the ion detection voltage; and a neutralization amplifier unit for at least partially neutralizing the voltage reduction of the voltage reduction circuit. The reduced voltage allows the use of low-voltage components, such as digital variable resistors.

The disclosure provides multimode configurable spectrometers, a method of operating a multimode configurable spectrometer, and an optical monitoring system. In one embodiment the multimode configurable spectrometer includes: (1) an optical sensor configured to receive an optical input and convert the optical input to electrical signals, wherein the optical sensor includes multiple active pixel regions for converting the optical input to the electrical signals, (2) conversion circuitry, having multiple selectable converting circuits, that is configured to receive and convert the electrical signals to a digital output according to a selected one of the selectable converting circuits, and (3) a sensor controller configured to set a synchronized operating mode to direct operation of the optical sensor and select, based on the synchronized operating mode, at least one of the selectable converting circuits to provide the digital output.

An example system includes a set of multipole electrodes and an RF generator configured to selectively output a signal voltage at a first frequency or at a second frequency for driving the set of multipole electrodes. The system also includes a low frequency transformer assembly and a high frequency transformer assembly. The system also includes a switching circuit configured to: connect the RF generator to a low frequency transformer assembly when the RF generator outputs an RF voltage at a first resonant frequency, the low frequency transformer assembly configured to supply the first voltage to an output coupled to the set of multipole electrodes based on the RF voltage; or connecting the RF generator to a high frequency transformer assembly when the RF generator outputs an RF voltage at a second resonant frequency, the high frequency transformer assembly configured to supply a second voltage to an output coupled to the set of multipole electrodes based on the RF voltage.

A method of mass spectrometry comprising: a) accumulating precursor ions in a first ion accumulator; b) performing a separation cycle including pulsing packets of precursor ions from the first ion accumulator to an ion separator and separating the precursor ions such that precursor ions having different values ​​of a first physicochemical property elute from the ion separator at different times; c) mass filtering the precursor ions eluting from the ion separator to transmit selected precursor ion species; and d) fragmenting or reacting the selected precursor ion species to produce a set of fragment or product ion species from the selected precursor ion species. e) accumulating the set of fragment or product ion species in a second ion accumulator; f) ejecting the set of fragment or product ion species from the second ion accumulator into a TOP mass analyzer, where operation of the TOP mass analyzer is synchronized with the ejection of ions from the second ion accumulator such that a plurality of different species of the set of fragment or product ion species are simultaneously pulsed by a pusher electrode into a time-of-flight region of the TOP mass analyzer; and g) repeating steps c)-f) at least once during a separation cycle, where the selected precursor ion species is different each time steps c)-f) are performed.

A mass spectrometer includes an orifice plate having an orifice, a first multipole ion guide in a first chamber downstream of the orifice plate, the first multipole ion guide including a plurality of rods, and a second multipole ion guide in a second chamber downstream of the first chamber, the second multipole ion guide including a plurality of rods. A first ion lens is between the first multipole ion guide and the second multipole ion guide. A third multipole ion guide is in a third chamber downstream of the second chamber, the third multipole ion guide including a plurality of rods. A second ion lens is between the second chamber and the third chamber. An adjustable DC voltage source applies an adjustable DC offset voltage to at least one of the above ion guides and ion lenses to increase the axial kinetic energy of the ions to cause at least one of de-clustering and / or fragmentation.

An ion detection current conversion circuit (153) comprises: - a conversion amplifier (152) coupled with a conversion resistor assembly for converting an ion detection current produced by an ion detector into an ion detection voltage, the conversion resistor assembly comprising a resistor (151) having a high resistance and a capacitive compensation element (157), and - a compensation voltage circuit (158) for deriving a compensation voltage (Vcomp) from the ion detection voltage (Vout) and feeding the compensation voltage to the capacitive compensation element (157), the compensation voltage circuit comprising a variable resistor (201) for adjusting the compensation voltage. The conversion circuit may further comprise a voltage reduction circuit (R15, R16, 220) for deriving a reduced voltage (Vred) from the ion detection voltage (Vout) and a neutralizing amplifier unit (211) for at least partially neutralizing the voltage reduction of the voltage reduction circuit. The reduced voltage allows low-voltage components, such as digital variable resistors, to be used.

Methods for operating a mass spectrometer, particularly an inductively coupled plasma mass spectrometer (ICP-MS), having a skimmer 30 and a circuit 40 for applying an electric potential to the skimmer

A high voltage power supply system for a mass spectrometer includes a ground referenced power supply having a first transformer with a primary winding and a secondary winding, the primary winding electrically coupled to a first AC power source, and a floating bias power supply having a second transformer with a primary winding and a secondary winding, the primary winding of the second transformer electrically coupled to a second AC power source. A return electrical path of the floating bias power supply is electrically coupled to the ground referenced power supply to bias an output voltage of the ground referenced power supply. A floating shield is disposed about the floating bias power supply and at least one resistive element is located in the return electrical path of the floating bias power supply to reduce noise coupled from the floating bias power supply to the ground referenced power supply.

A system for trapping ions for measurement thereof may include an electrostatic linear ion trap (ELIT), a source of ions to supply ions to the ELIT, a processor operatively coupled to ELIT, and a memory having instructions stored therein executable by the processor to produce at least one control signal to open the ELIT to allow ions supplied by the source of ions to enter the ELIT, determine an ion inlet frequency corresponding to a frequency of ions flowing from the source of ions into the open ELIT, generate or receive a target ion charge value, determine an optimum threshold value as a function of the target ion charge value and the determined ion inlet frequency, and produce at least one control signal to close the ELIT when a charge of an ion within the ELIT exceeds the optimum threshold value to thereby trap the ion in the ELIT.

A detection signal processing apparatus configured to process detection signals received from a detector for identifying the presence of one or more substances of interest in a sample, the apparatus comprising: a detection signal coupling arranged to receive detection signals from said detector; an amplifier and an integration capacitor, the amplifier having inputs, with at least one input being connected to the detection signal coupling; and ringing circuitry capacitively coupled to at least one of the inputs of the amplifier and being selectively operable to apply a ringing signal to said at least one of the inputs of the amplifier to cause amplifier protection circuitry of the amplifier to reset the integration capacitor.

An ion routing device is provided that has at least three branches that intersect at the junction. [Solution] Each branch defines an ion path through the ion routing device, and the ion path through each branch defines the longitudinal axis of the branch. Each branch is provided with longitudinally extending electrodes, and the longitudinally extending electrodes of each branch are electrically isolated from the longitudinally extending electrodes of adjacent branches. The ion routing device also includes a controller configured to control the passage of ions through the ion routing device. The controller is configured to provide an RF electrical signal to the longitudinally extending electrodes of each branch and to apply different DC biases to each RF electrical signal between the longitudinally extending electrodes of at least two of the adjacent branches.

An ion trapping device and a mechanism for determining a measure of capacitance of one or more electrodes of the ion trapping device are described. The ion trapping device includes a plurality of electrodes and a capacitance measurement device, which are formed in a same integrated circuit. The capacitance measurement device determines a measure of capacitance of a (sub-)set of the plurality of electrodes.

A detection signal processing device configured to process a detection signal received from a detector for identifying the presence of one or more target substances in a sample, the device comprising: a detection signal coupling arranged to receive a detection signal from the detector; an amplifier and an integrating capacitor, the amplifier having input terminals, at least one of which is coupled to the detection signal; and a ringing circuit capacitively coupled to at least one input of the amplifier and selectively operable to apply a ringing signal to the at least one input of the amplifier to cause an amplifier protection circuit of the amplifier to reset the integrating capacitor.

A quadrupole mass filter assembly comprises five quadrupole segments: RF-only entrance, middle and end segments, 21, 23 & 25; and primary and secondary resolving quadrupole segments, 24 & 22, configur

An ion routing apparatus is provided, the ion routing apparatus comprising at least three branches, the at least three branches intersecting at an intersection. Each branch defines an ion path through the ion routing device, the ion path through each branch defining a longitudinal axis of the branch. Each branch includes a longitudinally extending electrode, and the longitudinally extending electrode of each branch is electrically isolated from the longitudinally extending electrode of an adjacent branch. The ion routing device also includes a controller configured to control the ions to pass through the ion routing device. The controller is configured to provide an RF electrical signal to the longitudinally extending electrodes of each branch and to apply a DC bias to each RF electrical signal, the DC bias differing between the longitudinally extending electrodes of at least two of the adjacent branches.

A quadrupole mass filter assembly comprises five quadrupole segments. An entrance quadrupole segment is configured to receive RF voltages, a secondary quadrupole segment is arranged downstream of the entrance quadrupole segment and is configured to receive RF and resolving DC voltages. A middle quadrupole segment is arranged downstream of the secondary quadrupole segment and is configured to receive RF voltages. A primary quadrupole segment is arranged downstream of the middle quadrupole segment and is configured to receive RF and resolving DC voltages. An end quadrupole segment is arranged downstream of the primary quadrupole segment and is configured to receive RF voltages.