1031 results about "Mass analyzer" patented technology

The invention relates to the technical field of vacuum measurement, in particular to a device for expanding the linear range of mass spectrometry measurement, which comprises a gas transmission pipeline, an electromagnetic valve, a small hole and a mass spectrometer, and is characterized in that the front end of the gas transmission pipeline is used for allowing a sample to be measured to enter, and the rear end of the gas transmission pipeline is connected with the mass spectrometer; the middle part of the gas transmission pipeline is divided into three channels, namely a first gas transmission pipeline, a second gas transmission pipeline and a third gas transmission pipeline; the first electromagnetic valve and the first small hole are sequentially arranged on the first gas transmission pipeline, the second electromagnetic valve and the second small hole are sequentially arranged on the second gas transmission pipeline, and the third electromagnetic valve and the third small hole are sequentially arranged on the third gas transmission pipeline. According to the method, manual dilution or segmented sample injection is not needed, a wide concentration range can be covered by single analysis, more than 60% of time cost is saved, and measurement in a dynamic range of 106 is realized.

The invention discloses a helium detection device and method for the airtightness of a bonding interface and a bonding microcavity, and belongs to the field of the airtightness of MEMS devices. The device comprises a sample holder, a mass spectrometer, a molecular pump, a mechanical pump and other components, helium is used as detection gas, and the helium is leaked only through a bonding interface through a customized and processed test sample and sample holder structure, so that the interference of other leaks in a non-bonding area on a test result is avoided. The testing method comprises the steps of sample introduction, vacuum pumping, helium filling, signal detection, dynamic and steady state testing and the like, the helium leak rate is monitored in real time by combining with a helium mass spectrometer, and the minimum leak detection rate is that high-sensitivity air tightness detection is ensured. According to the method, the airtightness of the bonding interface can be independently evaluated, and a reliable basis is provided for development of a novel bonding process. The method is suitable for air tightness detection and evaluation of the bonding process in MEMS device processing and manufacturing.

The invention relates to the technical field of mass spectrometers, and discloses a mass spectrometer tuning method and device, electronic equipment, a storage medium and a program product, and the method comprises the steps: obtaining a tuning parameter data set of a target mass spectrometer, the tuning parameter data set comprising a plurality of tuning parameters and a parameter range corresponding to each tuning parameter; obtaining an optimization target of the target mass spectrometer; based on the tuning parameter data set, the optimization target and a pre-constructed constrained multi-target Bayesian optimization framework, predicting an optimal tuning parameter combination of the optimization target, the optimal tuning parameter combination being used for tuning the target mass spectrometer; the constrained multi-objective Bayesian optimization framework combines Bayesian optimization and multi-objective optimization. According to the invention, multi-objective optimization is carried out based on the constrained multi-objective Bayesian optimization framework, the optimal tuning parameter combination can be automatically generated, simultaneous tuning of multiple parameters of the mass spectrometer is realized, and the tuning performance and precision of the mass spectrometer are improved.

The invention relates to the technical field of molecular simulation, and provides a method for constructing a heavy component average molecular structure of thickened oil, which comprises the following steps: inputting parameters, generating a core aromatic ring unit, constructing an inner-layer aliphatic ring unit, constructing an outer-layer aliphatic ring unit, generating a side chain unit, and storing and outputting structural information. A plurality of molecular structures meeting experimental data are generated at a time through a traversal algorithm thought, composition characteristics of a heavy oil complex mixture are met, more available molecular structures are provided for molecular simulation, the accuracy and efficiency of molecular modeling are improved, the molecular structures completely meeting the experimental data can be rapidly generated, and the method is suitable for large-scale popularization and application. And only the mass spectrometer, the elemental analyzer, the nuclear magnetic resonance hydrogen spectrum and the infrared spectrum data need to be input, so that the experiment cost is reduced.

The application discloses a testing device and testing method for hydrogen isotope permeation parameters of fusion reactor application materials, relates to material testing technology in the hydrogen field, and belongs to the field of material testing technology in the hydrogen field. The testing device for hydrogen isotope permeation parameters of fusion reactor application materials comprises the following: a membrane sample is installed in a membrane testing cavity to divide the membrane testing cavity into a gas inlet sub-cavity and a permeation sub-cavity; a gas inlet tank is selectively communicated with the gas inlet sub-cavity to supply testing gas; a collecting tank is selectively communicated with the permeation sub-cavity to collect outflowing gas; a vacuum pumping structure is used for pumping the gas inlet sub-cavity and the permeation sub-cavity; a heating structure is used for heating the gas inlet sub-cavity and the permeation sub-cavity; a high-resolution mass spectrometer is selectively communicated with the permeation sub-cavity, and gas selectively flows into the high-resolution mass spectrometer. The testing device for hydrogen isotope permeation parameters of fusion reactor application materials can control the gas pressure and temperature in the two sub-cavities respectively, thereby accurately determining the hydrogen isotope permeation parameters of the materials, and the precision is high, and the data resolution is excellent.

A power supply device applies a voltage to a quadrupole mass filter. The power supply device has a main substrate and a wave-detection substrate. The main substrate includes a detector. The wave-detection substrate includes a wave detector and an identifier. The wave detector detects an AC component of a voltage to be applied to the quadrupole mass filter as a wave-detection voltage. The identifier outputs identification information of the wave detector defined in correspondence with the configuration of a rectifying device of the wave detector. The detector detects identification information output by the identifier, and supplies the detected identification information to a corrector that corrects a deviation of voltage caused by a leakage current of the rectifying device.

The utility model discloses a high-efficiency sampling device of an ultra-high performance liquid chromatography tandem mass spectrometer, which comprises a support, and a linkage adjusting mechanism is mounted in the middle of the top end of the support. The device has the beneficial effects that the linkage adjusting mechanism consisting of the racks, the sliding strips, the test tube placing seats, the clamping holes, the motor and the gear is mounted on the support, so that after a sample test tube on one test tube placing seat is used, the gear rotates under the action of the motor, and the gear can be matched with the corresponding rack after rotating; therefore, the used test tube placing seat slides out of the support, and the other test tube placing seat on which the sample test tube is placed is moved into the support, so that the sample test tube on the other test tube placing seat can be continuously fed when the sample test tube on one test tube placing seat is replaced, and the sample test tube on the other test tube placing seat can be conveniently replaced. The interruption of the sample introduction process of the ultra-high performance liquid chromatography tandem mass spectrometer is avoided, and the sample introduction efficiency of the ultra-high performance liquid chromatography tandem mass spectrometer is higher.

The invention discloses a device and a detection method for online oxidation-enrichment-reduction determination of nanogram-level nitrogen isotopes in a solid, and belongs to the technical field of nitrogen isotope analysis. The device comprises an oxidation system, a nitrogen oxide enrichment system, a nitrogen reduction system, a mass spectrum interface system, a stable isotope ratio mass spectrometer and pipelines for connecting all parts of the device. The device provided by the invention greatly reduces the quantitation limit of the nitrogen isotope in the solid sample, can realize high-precision determination of the nanogram-level nitrogen isotope in the solid sample, and has the advantages of simplicity and convenience in operation, high accuracy and the like.

In a mass spectrometer (10) for gas analysis, comprising: a mass spectrometer housing (12) evacuated by a vacuum pump; an ion source (16) for ionizing gas atoms or molecules entering the mass spectrometer enclosure (12) and accelerating ions in the mass spectrometer enclosure (12); an ion trap (22) made of an electrically conductive material for collecting ions generated by the ion source (16); an electrical measurement device (24) for measuring the potential or current of the ion trap (22) and connected to the ion trap (22) for inferring the ions collected by the ion trap (22) from the measured potential or current; a magnetic or electromagnetic deflection device configured to deflect or map ions having a specific mass-to-charge ratio to the ion trap (22); an electron barrier (30) made of an electrically conductive material is provided at the ion trap (22), the electron barrier having a lower potential than the ion trap (22) and being configured to generate a reverse electric field to return electrons released from the ion trap (22) onto the ion trap (22).

The invention relates to the technical field of vacuum equipment, and discloses an ion lens assembly, an ion source, a mass spectrometer and a mass spectrometry system. The ion lens assembly includes a deflection lens assembly and a return lens assembly. The deflection lens assembly is used for focusing an ion beam in the incident particle beam and enabling the ion beam to deflect towards a first direction. And the axis-returning lens assembly is used for receiving the ion beam from the deflection lens assembly, and the axis-returning lens assembly is used for focusing the received ion beam and enabling the ion beam to deflect towards a second direction.

The invention belongs to the technical field of geological sample analysis and detection, and particularly discloses a method for measuring the amount of each element of lithium ore in a closed acid-soluble system, and the method comprises the following steps: pretreating the lithium ore; the pretreated lithium ore is weighed and put into a closed sample dissolving device, hydrofluoric acid and purified nitric acid are sequentially added, and the closed sample dissolving device is closed; carrying out heat preservation on the closed sample dissolving device twice to obtain a test solution; and measuring the test solution by using an inductively coupled plasma mass spectrometer to obtain a working curve, and calculating the content of the analysis element in the sample solution by using the working curve. The method for determining the amount of each element in the lithium ore by adopting the closed acid-soluble system has the characteristics of simplicity in operation, high efficiency and good stability, realizes simultaneous determination of the amount of lithium, rubidium, cesium, beryllium, strontium, niobium, tantalum, zirconium, hafnium and rare earth elements in the large-batch lithium ore, and further provides a reference for determination of main trace elements in the lithium ore.

A mass or mobility spectrometer comprising: a first vacuum chamber; and a collision cell arranged in the first vacuum chamber, wherein the collision cell comprises: an ion entrance at an upstream end thereof; an ion exit at a downstream end thereof; a main body portion between the ion entrance and ion exit; and an elongated tube between the main body portion and the ion exit. The collision cell comprises one or more ion guide extending through the main body portion, and / or through the elongated tube, for radially confining ions within the one or more ion guide. The spectrometer is configured to maintain the main body portion of the collision cell at a higher pressure than the first vacuum chamber; and the elongated tube is configured to limit the gas conductance out of the downstream end of the collision cell.

The invention discloses a method for detecting the content of trace metal ions in a diazo naphthoquinone photosensitizer. The method comprises the following steps: sample pretreatment: weighing diazonaphthoquinone photosensitizer powder in a clean room, putting the diazonaphthoquinone photosensitizer powder into a cleaned and dried wide-mouth PFA bottle, adding an organic reagent, and carrying out ultrasonic treatment until a solid is completely dissolved; the method comprises the following steps: testing: adding a metal standard substance into an organic solvent to prepare three standard solutions with different concentrations; debugging an instrument, determining target metal in the standard solution in a Cool mode, a No Gas mode and a He mode by using an inductively coupled plasma mass spectrometer to obtain a signal intensity value (CPS value) corresponding to each metal ion concentration in the standard solution, and establishing a standard curve; and measuring the sample in which the photosensitizer is dissolved by using the same steps to obtain the content of metal ions in the sample. According to the method, appropriate detection conditions are optimized for different elements to be detected in the diazo naphthoquinone photosensitizer, polyatomic ion interference and matrix effect in a sample are mainly reduced, the content of 16 metal ions can be accurately detected at the same time, and the test efficiency is high.

A trace of intensity versus time values is received for a series of samples produced by a mass spectrometer. Also, a series of ejections times corresponding to the series of samples produced by a sample introduction system is received. A series of expected peak times corresponding to the series of ejection times are calculated using a known delay time from ejection to mass analysis. At least one isolated peak of the trace is identified using the series of expected peak times. A peak profile is calculated by fitting a mixture of at least two different distribution functions to the at least one isolated peak. For at least one time of the series of expected peak times, an area of a peak at the one time is calculated by fitting the peak profile to the trace at the one time and calculating an area of the fitted peak profile.

An exemplary breath analysis system may include a sampling chamber having a molecule collector disposed therein. The molecule detector may be configured such that volatile organic compounds (VOCs) present in a breath sample introduced to the sampling chamber adhere to the molecule collector. A heating element may introduce heat within the sampling chamber, causing release of at least a portion of the VOCs adhered to the molecule collector. An analysis device (e.g., a mass spectrometer or terahertz (THz) spectrometer) may identify one or more target VOCs from among at least the portion of the VOCs released from the molecule collector and generate an output representative of the identified one or more target VOCs. The output may include information that quantitates a concentration of the one or more target VOCs with respect to a source of the breath sample.

Systems and methods are disclosed for automated method parameter configuration for differential mobility separations. As non-limiting examples, various aspects of this disclosure provide receiving a sample in an open port interface; transferring the sample to an ionization source; ionizing the transferred sample; introducing the ionized sample into a mass spectrometer; mass analyzing the ionized sample to produce an initial mass analysis result; determining a peak width of the initial mass analysis result; and determining a dwell time for subsequent measurements based on the determined peak width, a pre-defined number of data points across subsequent mass analysis peak widths, and a number of different analytes to be assessed for the sample. The sample may be diluted and transferred to the ionization source by a sample introduction apparatus selected from a group including an acoustic droplet ejector (ADE), a pneumatic ejector, a piezoelectric ejector, and a hydraulic ejector.

Determination of sensitive and accurate feature values from a matrix-assisted laser desorption / ionization (MALDI) spectrum of a sample is provided. A peak shape function of the mass spectrometer is read. A fine structure component is determined for a first range of the mass spectrum by estimating and subtracting a first background from the mass spectrum. A bump structure is determined for the first range by estimating a second background, which is stiffer than the first background, and subtracting it from the first background. A convolution of the fine structure component is computed for the first range of the mass spectrum with the peak shape function. A first plurality of peaks in the first range is determined from the convolution. A feature value indicative of an abundance associated with each of the first plurality of peaks is determined by combining the first plurality of peaks with the bump structure.

The utility model discloses a pressing device for a powder sample and a high-purity indium sheet of a glow discharge mass spectrometer, and belongs to the field of glow discharge mass spectrometry in chemical component analysis. The device comprises an external supporting and protecting system, an internal tabletting system and upper and lower pressing dies. The external supporting and protecting system comprises a touch screen, a protective cover, a safety grating, a control box and the like. The internal tabletting system is composed of an equipment base, a fixed stand column, a movable table, an electric push cylinder, a pressure sensor and the like, and the movable table is driven by the electric push cylinder to drive a lower pressing die to move upwards to be matched with a fixed upper pressing die to complete pressing. The device adopts replaceable upper and lower pressing dies and a sample pressing ring, and meets the preparation requirements of samples with different sizes. The device solves the problems that a powder sample is difficult to compact and the thickness of the prepared indium sheet is not uniform, the pressing parameters are controlled in a programmed manner, the prepared sample can be directly tested without demolding, the integrity of the sample and the test accuracy are effectively ensured, the operation is safe, the efficiency is high, and the economical efficiency is good.

The application belongs to the technical field of chemical detection, and particularly relates to a Raman-LIBS-mass spectrometry combined analysis device and analysis method. The Raman-LIBS-mass spectrometry combined analysis device comprises a multiple-reflection time-of-flight mass spectrometer, a LIBS spectrometer, a Raman spectrometer and a shared module. The shared module comprises a first incident light path system, a second incident light path system, a high-definition observation system, a vacuum sample bin, a vacuum system and a control system. The first incident light path system is used for generating a femtosecond laser beam and performing three-dimensional ablation on a sample. The second incident light path system is used for combining tunable lasers into a resonance ionization light path. Compared with the prior art, the application can realize in-situ micro-area ultra-high resolution element and isotope analysis and imaging, realize ultra-trace element, isotope analysis and isotope ratio analysis under strong matrix interference, and can also perform high-resolution molecular structure and composition analysis and Raman scattering imaging.

The invention discloses a method for analyzing component difference between Maotai-flavor yeast and yeast-making wheat by using non-targeted metabonomics. The method comprises the following steps: S1, pre-treating a sample; s2, detecting each sample by adopting the combination of an ultra-high performance liquid chromatograph and a quadrupole time-of-flight mass spectrometer; s3, acquiring original data, performing peak extraction, peak alignment and normalization by adopting metabonomics data analysis software, and evaluating the overall difference and intra-group variation among sample groups by adopting principal component analysis; constructing a grouping discrimination model through discriminant analysis of an orthogonal partial least square method; determining differential metabolites of the two groups of samples by taking variable projection importance (VIP) greater than 1 and statistical significance P less than 0.01 as a primary screening standard and combining a secondary screening standard that the difference multiple log2FC greater than 2 is up-regulated and the difference multiple log2FC less than-2 is down-regulated; s4, performing compound structure and category annotation on the screened differential metabolites through a metabolome database; and performing pathway enrichment analysis by adopting a statistical test method, and determining a core metabolic pathway enriched by the differential metabolites.

In various aspects, microscope systems are described, comprising or corresponding to optical microscopes, such as for example a transillumination microscope or a fluorescence microscope. The microscope systems may be used independently or configured with or integrated into another device or system, such as an imaging mass spectrometer or imaging mass cytometer. In various embodiments of this aspect, the microscope system is used to obtain one or more images of a sample, such as at a variety of different light collection wavelengths and / or for a variety of different illumination conditions. The microscope systems can employ various optical components and configurations allowing for high throughput imaging, such as components for imaging the sample at suitable resolutions with a wide field of view and / or for spatially separating different detection channel wavelengths from light output (e.g., transmitted or emitted light) from the sample.

The invention discloses an intelligent risk supervision and early warning system for steel strip production, and belongs to the technical field of steel strip production, and the system specifically comprises the steps: synchronously collecting sound wave signals and hydrogen concentration change data in a cleaning process through a sound wave sensor and a hydrogen mass spectrometer, and building a mapping model of sound pressure level data and a reaction rate; the method comprises the following steps: acquiring an actual reaction rate curve of a current steel strip in a preset observation window, and matching with a historical production database to obtain a reference similar curve; and generating a process parameter adjustment scheme of the current steel strip based on the process parameters corresponding to the reference similar curve, and performing dynamic correction according to the deviation condition of the real-time reaction rate curve and the reference curve. Accurate sensing and self-adaptive control over the reaction state in the cleaning process are achieved, the problem of uneven cleaning caused by the difference of the surface states of the steel strips is effectively solved, and the stability of the cleaning quality and the production efficiency are improved.

Systems / techniques are provided for facilitating mass analyzer calibration via reinforcement learning. In various embodiments, a system can predict, via execution of one or more reinforcement learning neural networks on present-time state data of a mass analyzer of a scientific instrument, what adjustments to one or more operational parameters of the mass analyzer would cause the mass analyzer to approach a calibrated state, wherein the one or more operational parameters include an electrode voltage of the mass analyzer or a timing control of the mass analyzer. In various aspects, the system can modify the one or more operational parameters based on the adjustments, thereby causing the mass analyzer to approach the calibrated state.

Methods and systems for multi-beam, parallel-beam, deterministic, or super mass spectrometry that include an ion source that produces ions, and two or more ion trapping devices or mass spectrometers, each having an independent sampling inlet. The two or more ion trapping devices or mass spectrometers receive the ions from the ion source via the sampling inlet of each of the ion trapping devices or mass spectrometers such that each sampling inlet provides an ion beam to each corresponding ion trapping device or mass spectrometer.

The invention discloses a method and a system for detecting matrix impurity elements in photovoltaic polycrystalline silicon, and relates to the technical field of detection of matrix impurities of polycrystalline silicon, and the method comprises the following steps: collecting multi-dimensional data by built-in and external sensors of a mass spectrometer; comprising the following steps: continuously acquiring full-mass-range original ion counting signals from a mass spectrometer at high time sequence resolution, synchronously acquiring instrument working parameters and laboratory environment parameters, and synchronizing through a uniform timestamp to form a multi-dimensional data cube; according to the method, the dynamic background change model is established by introducing an associated detection instrument and environmental parameters and collecting multi-dimensional data in real time, the inherent mode of static background deduction is changed, and background interference is predicted and deducted more accurately, so that the accuracy of quantitative analysis of the ultra-trace impurities is improved, and the detection efficiency is improved. And moreover, the influence of instrument and environmental factors on the background interference is comprehensively considered, and the background interference of dynamic change is predicted and stripped in real time.

Provided are a scintillator and the like capable of improving emission intensity. A scintillator (S) comprises a sapphire substrate (6), a GaN layer (4) that is provided on the incident side to the sapphire substrate (6) and includes GaN, a quantum well structure (3) provided on the incident side to the GaN layer (4), and a conductive layer (2) provided on the incident side to the quantum well structure (3), wherein a plurality of emitting layers (21) including InGaN and a plurality of barrier layers (22) including GaN are alternatively stacked in the quantum well structure (3), and an oxygen-containing layer (23) including oxygen is provided between the quantum well structure (3) and the conductive layer (2).

A high mass ion detector for a mass spectrometer, a mass spectrometer, and a method for detecting high mass ions are provided.

The utility model discloses a droplet microextraction-flow type electrospray ionization device, which belongs to the technical field of chemical analysis and comprises a digital peristaltic pump, a direct-current high-voltage power supply, a stainless steel two-way connector and a conductive metal transmitting tube. A transmission hose is arranged on the digital peristaltic pump, one end of the conductive metal transmitting tube is connected with the transmission hose of the digital peristaltic pump through a stainless steel two-way connector, the other end of the conductive metal transmitting tube corresponds to a mass spectrometer inlet and is used for generating electrospray, and the direct-current high-voltage power supply is electrically connected with the conductive metal transmitting tube. The direct-current high-voltage power supply applies voltage to the conductive metal transmitting tube; according to the droplet microextraction-flow type electrospray ionization device adopting the structure, micro-droplet flow type sample injection and non-contact flow type sample injection are combined, and electrospray can be stably generated under the condition of not depending on gas assistance.

The utility model relates to the technical field of waste gas emission devices, and discloses a waste gas emission device which comprises a waste gas emission assembly. According to the waste gas emission device and the liquid chromatography tandem mass spectrometer, a plurality of gas inlet pipes and an exhaust main pipe are integrated through the treatment box, multi-channel waste gas centralized treatment is achieved, the servo motor drives the reciprocating lead screw to drive the cleaning brush to reciprocate along the guide rod, a filter screen made of a stainless steel sintered mesh material is automatically cleaned, blockage is avoided, and the working efficiency is improved. The fan assembly accelerates waste gas flowing through a gas collecting hood, a rotating shaft of the fan assembly is in linkage with a first chain wheel, a second chain wheel and a chain through a first bevel gear, a transmission rod and a second bevel gear, the cleaning system can drive the auxiliary exhaust function to work, extra energy consumption is not needed, and the device is more practical; a waste gas pipe on the liquid chromatogram tandem mass spectrometer body is communicated with a gas inlet pipe on one side of the treatment box through a second one-way valve and a second electromagnetic valve, so that directional conveying of waste gas is ensured, and the scheme realizes a self-cleaning effect through mechanical linkage.

The invention relates to the technical field of mass spectrometers, and discloses an analytical instrument based on glow discharge and quadrupole mass spectrometry combination, which comprises an ion source, an ion transmission system and an ion separator, wherein the ion source is a glow discharge ion source; the ion separator is a quadrupole rod mass analyzer, and the quadrupole rod mass analyzer comprises four electrodes which are arranged in parallel. Compared with an existing analytical instrument, the glow discharge ion source can directly analyze a solid sample without being pretreated into a solution, and compared with an inductively coupled plasma source, the glow discharge ion source is small in matrix effect and especially suitable for high-salt and high-carbon samples; the quadrupole rod mass analyzer is simple in structure, small in size, low in cost, especially suitable for commercialized popularization and high in scanning speed.