The invention discloses a method and a device for performing energy resolution
cascade mass spectrometry on a sample based on an
ion trap, and the method comprises the following steps: performing
ionization treatment on a to-be-detected sample to obtain to-be-detected ions; enabling the to-be-detected ions to enter a linear
ion trap, and screening out target ions; amplitude scanning
processing is carried out on the target ions, and the amplitude scanning
processing comprises the steps that first alternating
voltage is applied to the x direction of the linear
ion trap so that the target ions can be cracked into
daughter ions, and meanwhile second alternating
voltage is applied to the y direction of the linear
ion trap so that the
daughter ions can be separated from the linear
ion trap; enabling a
detector to obtain the
daughter ions so as to obtain a detection result of the to-be-detected sample. According to the method disclosed by the invention, continuous energy scanning and fragmentation of parent ions can be realized through the first alternating-
current voltage amplitude which is increased along with time by utilizing a
single ion trap and only through
single sample introduction, and daughter ions are synchronously emitted by utilizing the constant second alternating-
current voltage amplitude in the orthogonal direction for detection; and the efficiency and the accuracy of energy resolution
cascade mass spectrometry are improved.