352results about "Mass spectrometers" patented technology

The invention discloses an ion trap mass spectrometry device and method capable of switching internal and external ion sources, and the device comprises an ion source cavity, the exterior of the ion source cavity is provided with a heating module, the side wall of the ion source cavity is provided with a sample introduction hole, and the sample introduction hole is internally provided with a chromatographic column I; the electron beam generation system is arranged at the front side position of the ion source cavity; the insulation connecting piece is communicated with the ion source cavity, and a lens I, a lens II and a lens III are sequentially arranged in the insulation connecting piece in the sample injection direction; a signal acquisition system; wherein a chromatographic column II is arranged on the ion trap. The two ionization modes inside and outside the trap are integrated, and different detection requirements can be flexibly met by switching the sample introduction path of the chromatographic column and regulating and controlling the voltage parameters of the lens I, the lens II and the lens III.

An inlet for an analytical instrument comprises a transfer tube having an upstream end and a downstream end and a deposition region arranged at or adjacent to the upstream end of the transfer tube. The transfer tube is configured to transfer ions together with a gas flow from the upstream end to the downstream end. The transfer tube and the deposition region are configured such that the gas flow experiences at least one turn in the deposition region, whereupon relatively large particles entrained in the gas flow are deposited in the deposition region. The at least one turn in the gas flow is created by: a change in cross-sectional area of the gas flow in the deposition region, a change in diameter of the gas flow in the deposition region, and / or a change in cross-sectional shape of the gas flow in the deposition region.

Systems and approaches for semiconductor metrology and surface analysis using Secondary Ion Mass Spectrometry (SIMS) are disclosed. In an example, a secondary ion mass spectrometry (SIMS) system includes a sample stage. A primary ion beam is directed to the sample stage. An extraction lens is directed at the sample stage. The extraction lens is configured to provide a low extraction field for secondary ions emitted from a sample on the sample stage. A magnetic sector spectrograph is coupled to the extraction lens along an optical path of the SIMS system. The magnetic sector spectrograph includes an electrostatic analyzer (ESA) coupled to a magnetic sector analyzer (MSA).

The invention relates to the technical field of analysis instrument ionization sources, in particular to a VUV lamp ionization source device with efficient heat dissipation capacity. The device comprises a VUV lamp, a heat dissipation unit, a VUV lamp driving electrode, a driving circuit and an ion guide focusing unit. The heat dissipation unit carries out cooperative heat dissipation on the VUV lamp and the pulse transformer through a fan, and the problems of signal attenuation and device aging caused by temperature rise are solved. The driving electrode adopts a pairwise pairing structure of upper and lower and left and right electrode pairs to form an inclined electric field to prevent ions from bombarding the lamp wall and the light window; the drive circuit is a half-bridge or full-bridge topology, can adjust the pulse frequency and the power supply voltage, and achieves the switching between a high-voltage low-frequency mode and a low-voltage high-frequency mode. The ion guide focusing unit efficiently leads out and separates ions through cooperation of a conical focusing electric field and a conductive film forward electric field. Through four-dimensional innovation of heat dissipation, electrodes, driving and transmission, the stability, the service life and the detection sensitivity of the device are improved, and the device is suitable for analytical instruments such as ion mobility spectrometry and mass spectrometry.

Disclosed herein are methods and systems for individual ion mass spectrometry (I2MS). The methods and systems described herein parse I2MS data and allows for informed tandem mass spectrometry analyses by determining a target m / z that increases the yield of an intact mass corresponding to an analyte of interest while reducing the yield of additional detectable masses.

The utility model discloses a droplet microextraction-flow type electrospray ionization device, which belongs to the technical field of chemical analysis and comprises a digital peristaltic pump, a direct-current high-voltage power supply, a stainless steel two-way connector and a conductive metal transmitting tube. A transmission hose is arranged on the digital peristaltic pump, one end of the conductive metal transmitting tube is connected with the transmission hose of the digital peristaltic pump through a stainless steel two-way connector, the other end of the conductive metal transmitting tube corresponds to a mass spectrometer inlet and is used for generating electrospray, and the direct-current high-voltage power supply is electrically connected with the conductive metal transmitting tube. The direct-current high-voltage power supply applies voltage to the conductive metal transmitting tube; according to the droplet microextraction-flow type electrospray ionization device adopting the structure, micro-droplet flow type sample injection and non-contact flow type sample injection are combined, and electrospray can be stably generated under the condition of not depending on gas assistance.

According to the ion regulation and control device, the ion guide device, the control method, the device, the equipment and the ion guide system provided by the invention, the first guide element and the deflection force field generation module are arranged, under the condition that ions are injected into the first guide element, the first guide element is controlled to apply the reverse electric field opposite to the ion transmission direction, and the deflection force field is generated; thereby trapping ions within the first guide element; controlling the deflection force field generation module to work so as to enable the ions in the first guide element to generate radial deflection; and under the condition that offset is completed, the first guide element is controlled to cancel the reverse electric field so that the first guide element can move in the transmission direction, ions in the first guide element can generate radial offset through the deflection force field generation module, the ions can be more uniformly distributed in the radial direction, and therefore the space area utilization rate is increased, and the transmission efficiency is improved. And the influence of the space charge effect is reduced.

The invention relates to an ion-optical component comprising at least one electrode arrangement (12) with a circular segment-shaped inner electrode (17) and an annular segment-shaped outer electrode (18) circumferentially surrounding the inner electrode (17), as well as with two circular segment-shaped plates (23) which are surrounded on both sides of the inner electrode (17) and circumferentially by the outer electrode (18) and form a uniform annular segment-shaped gap (25) between each of the plates (23) and the outer electrode (18), wherein the ion-optical component comprises two electrode arrangements (12) which each extend over a sector with an angle ϕ / 2, where 90°<ϕ<180°, and are arranged one behind the other in such a way that a trajectory of an ion beam (14) through the ion-optical component is s-shaped.

The utility model discloses a Faraday cup of an ion receiver of a thermal ionization mass spectrometer, which comprises a non-metal receiving support, a non-metal receiving electrode and a pair of external fixing metal plates, the non-metal receiving support is concaved inwards to form a notch communicated with the outside, the non-metal receiving electrode is arranged in the notch, and the external fixing metal plates are fixed on the non-metal receiving support. The pair of external fixing metal plates are oppositely fixed on the two side surfaces of the non-metal receiving bracket, and the external fixing metal plates and the non-metal receiving bracket are encircled to enable the notch to only have a state that the top is communicated with the outside, so that the whole Faraday cup retains the rigidity of metal, the outside is not easy to deform, and the service life of the Faraday cup is prolonged. The non-metallic material is adopted in the device, so that the device has the characteristic of not rebounding ions, interference on ion measurement can be effectively reduced, and the measurement accuracy is improved.

The invention discloses a multi-wavelength light-induced photoelectron charge compensation device and method for SIMS analysis, and the device comprises an adjustable wavelength light source which is used for generating light of which the wavelength is adjustable in a range from ultraviolet to visible light; the optical system is used for guiding the light generated by the adjustable wavelength light source to the surface of a sample bombarded by an SIMS primary ion beam, and ensuring that a photon beam spot is accurately overlapped with an ion beam bombarded area; and the control unit is used for dynamically adjusting the wavelength and the light intensity of the adjustable wavelength light source according to the stability of the SIMS secondary ion signal so as to optimize photoelectron emission and realize charge neutralization. The invention has the following beneficial effects: the technical scheme avoids physical damage of the electron gun to the sample and damage to the vacuum environment; the wavelength can be adjusted to cover ultraviolet light to visible light, and the device is suitable for various materials.

This invention provides a cryo-laser ablation chamber for reflected light fluid inclusions, belonging to the field of geosciences for the analysis of the composition of single fluid inclusions. The device mainly consists of an outer shell, a cryo chamber, an ablation chamber, and a top cover. The cryo chamber, located at the bottom of the outer shell, is made of pure silver, and its top is mirror-polished and connected to a liquid nitrogen tank and pump via a Teflon hose. The ablation chamber, located above the liquid nitrogen chamber, has a standard sample mounting hole. The chamber is spindle-shaped and has inlet and outlet ports at both ends, connected to a carrier gas pipeline. The top cover is equipped with a calcium fluoride glass viewing window, allowing 193nm laser light to pass through. This invention uses a silver cryo chamber to ensure the required cooling effect; simultaneously, the mirror design at the top of the cryo chamber converts the light emitted by the reflected light microscope into transmitted light, thus enabling precise observation and positioning of the fluid inclusions under test without relying on conventional transmitted light systems.

The application discloses a kind of mass spectrometry nanoliter ion source and the adjusting method of mass spectrometry nanoliter ion source, it is related to mass spectrometry technical field, the mass spectrometry nanoliter ion source includes: ion source cover, vacuum interface cavity is equipped in the ion source cover, the end of the vacuum interface cavity forms conical cover, quadrupole rod and vacuum pump interface are equipped in the vacuum interface cavity, sample inlet hole is equipped on the conical cover;Adjusting mechanism, the adjusting mechanism is fixedly arranged with the relative position of the ion source cover;Nanoliter spray needle, the nanoliter spray needle is equipped on the adjusting mechanism, the nanoliter spray needle is suitable for adjusting the distance and / or attitude between the sample inlet hole by the adjusting mechanism, the nanoliter spray needle is connected with electricity to be configured to make the nanoliter spray needle and the conical cover form the electric field that makes target ion move towards the conical cover.The mass spectrometry nanoliter ion source according to the embodiment of the application has the advantages of high ionization efficiency, short trapping time, good applicability and the like.

A power supply system 1 for a mass spectrometer. The system comprises a positive voltage supply and negative voltage supply, and first and second optocouplers 19, 20 which are controlled by a controll

The invention discloses a plasma electrospray fusion ionization source and mass spectrum combined system and a detection method. The plasma electrospray fusion ionization source and mass spectrum combined system comprises a coaxially nested electrospray needle, a sample injector, an ultrahigh voltage generator, a grounded metal grid mesh, a mass spectrometer and a detector thereof. A grounded metal grid is installed between a spray needle and a mass spectrum inlet, voltage is applied to the spray needle, carrier gas is excited to generate plasmas, the macroscopic plasmas at the front end of the spray needle are fused with electrospray, and the plasmas and micro-droplets at the tip of the spray needle are fused. According to the unique ionization source constructed by the plasma-micro-droplet fusion system, on one hand, the ionization efficiency is improved, mass spectrum signals are enhanced, the application range of analytes is widened, excellent sensitivity to high-polarity compounds is kept, and effective ionization and detection of low-polarity compounds are achieved; on the other hand, higher energy and active species are provided for the micro-droplet reaction, the energy barrier required by traditional synthesis is broken, and efficient spontaneous product generation of the micro-droplet chemical reaction is achieved.

The invention provides a winding type ion transmission device based on a flexible printed circuit board, which not only can realize high-efficiency transmission of ions from a high-air-pressure ion source to a high-vacuum mass analyzer, but also can solve the problems of difficulty in machining and manufacturing, high cost, poor batch consistency and the like of a traditional metal machine. Comprising a flexible printed circuit board, the flexible printed circuit board is wound to form a conical ion transmission channel, a plurality of electrode sets are annularly arranged on the wound flexible printed circuit board, and each electrode set comprises a plurality of electrodes sequentially arranged in the axial direction of the ion transmission channel. Voltages with different phases are applied to the electrode group, so that a radial resonance bound electric field is formed, and a continuous axial direct-current gradient field of which the voltage drop is gradually reduced along the ion transmission direction is formed.

The invention provides an ion optical system high-voltage power supply for a mass spectrometer, and relates to the technical field of high-voltage power supplies, and the ion optical system high-voltage power supply for the mass spectrometer comprises a high-voltage input module of which the output end is connected with the first input end of a modulation circuit so as to provide a first input voltage for the modulation circuit; the input end of the low-voltage input module is in communication connection with the output end of the mass spectrometer, and the output end of the low-voltage input module is connected with the second input end of the modulation circuit so as to provide second input voltage for the modulation circuit; and the output end of the modulation circuit is connected with the input end of the mass spectrometer so as to modulate the second input voltage to obtain a target voltage. According to the ion optical system high-voltage power supply for the mass spectrometer, the low-voltage control signal is modulated into the target voltage through efficient communication with the control system of the mass spectrometer, and the diversified voltage requirements of the ion optical system of the mass spectrometer in different working modes are met.

This invention relates to a high-efficiency ion current acquisition structure and a mass spectrometer. The ion current acquisition structure includes: a collection chamber adapted to be installed between the ion source and the sampling cone of the mass spectrometer; a trumpet-shaped aperture disposed within the collection chamber at the end facing the ion source; an annular electrode disposed on the inner wall of the trumpet-shaped aperture; and a beam rod assembly comprising multiple rod-shaped electrodes uniformly arranged circumferentially along the outlet of the trumpet-shaped aperture, with adjacent rod-shaped electrodes spaced apart to form gaps; wherein, on the side away from the ion source, the ends of the multiple rod-shaped electrodes are all bent and converged towards the central axis of the collection chamber. This invention provides a high-efficiency ion current acquisition structure that can improve the technical problems of low ion acquisition efficiency before entering the vacuum system and high background noise caused by the inability to effectively filter neutral particles in the prior art.

The invention relates to the technical field of mass spectrum detection, particularly discloses a mass spectrum ionization source for detecting volatile substances in combination with radio frequency discharge, and solves the problems of tedious sample pretreatment steps, long analysis period, high instrument cost and the like when a traditional ion source is used for analyzing the volatile substances in the existing mass spectrum technology. The ionization source is used for ionizing molecules of a sample to be detected; the mass spectrometric detection method of the ionization source comprises the steps that stable low-temperature plasma is generated under the atmospheric pressure condition through radio frequency discharge, the low-temperature plasma directly interacts with an introduced to-be-detected sample, volatile substance molecules in the to-be-detected sample are efficiently ionized, and then generated ions are introduced into a mass spectrometer for analysis. The device has the advantages of being simple in structure, convenient to operate, free of complex sample pretreatment, high in analysis speed and the like, and an efficient and economical new way is provided for rapid and direct detection of volatile substances.

The utility model relates to the technical field of mass spectrometers, in particular to a mass spectrometer filament belt burning device which comprises a shell, the left side of the shell is fixedly connected with a molecular pump, the top of the shell is provided with a box cover, and the bottom of an inner cavity of the shell is fixedly connected with a fixing block. The lamp filament fixing device has the advantages of being capable of fixing lamp filaments of different specifications and convenient to disassemble, stable clamping of the lamp filaments of different specifications can be achieved through the arrangement of the fixing mechanism in the actual use process, the universality of the device is improved, the stability and safety of the lamp filaments in the installation process are guaranteed, and the service life of the lamp filaments is prolonged. According to the lamp filament inserting disc, the problem of installation difficulty or lamp filament loosening caused by mismatching of specifications is avoided, the lamp filament inserting disc can be easily locked and unlocked through the arrangement of the locking mechanism, a user can rapidly complete installation and disassembly of the lamp filament inserting disc only through simple up-down movement operation, and the working efficiency and the operation convenience are greatly improved.

This invention discloses a mass spectrometry ionization method based on the Tesla coil principle. It utilizes a Tesla coil to generate a micro-plasma beam, which serves as the ion source. Liquid samples are desorbed and introduced into the micro-plasma beam region for ionization, or gas samples are directly introduced into the micro-plasma beam region for ionization. This invention, by creatively using a Tesla coil-generated micro-plasma beam as the ion source, not only achieves strong ionization capability and good ionization effect on volatile gas samples and low-polarity or non-polar liquid samples, but also requires sample volumes as low as picoliters to microliters, exhibits good solvent compatibility and strong salt resistance, and further possesses advantages such as simple operation, low cost, ease of implementation, and broad applicability.

An amplifier arrangement for providing a variable electrode voltage to an ion optical device. The amplifier arrangement comprises a high speed amplifier designed to receive an input signal to the amplifier arrangement and provide a low voltage output, and a low speed adjustable voltage source arranged to float above the low voltage output and configured to provide a high voltage output of the amplifier arrangement. The high voltage output of the amplifier arrangement is fed back to control the high speed amplifier. Advantageously, the amplifier arrangement forms part of a power supply for providing a varying electrode voltage, for example as part of an ion analysis system.

A heating device and a mass spectrometry device of a nanoelectrospray source, the heating device comprising: a support body and a heating body arranged on the support body, the heating body being configured to apply a heating effect to an ion transmission path and being provided with an ion transmission channel for the passage of ions or charged droplets; an ion inlet of the ion transmission channel corresponding to an ion outlet of the nanoelectrospray source, and an ion outlet of the ion transmission channel corresponding to an ion inlet of the mass spectrometer. The heating device can significantly improve the atomization and desolvation capability of the nanoelectrospray source, improve the signal response and repeatability, reduce the ion cluster background noise formed by solvent molecules, improve the sensitivity, and avoid the spray stop and signal loss caused by the heat-sensitive drying of the nanoelectrospray ion source at the end of the spray needle.

Methods for acquiring mass spectral data of a sample across at least a portion of an m / z range include receiving mass spectral data of the sample across the m / z range. The m / z range is partitioned into one or more sets of m / z sub-ranges, each set comprising one or more m / z sub-ranges, by dividing the m / z range into a plurality of m / z bins, determining an indication of ion abundance for each m / z bin, based on the mass spectral data, and forming an m / z sub-range of the one or more sets of m / z sub-ranges by assigning m / z bins having ion abundances that correspond to at least a threshold degree to the formed m / z sub-range. A mass analysis is performed on the sample for each set of m / z sub-ranges, thereby acquiring one or more partial mass spectral data sets.

A deposit reduction ionization source for introducing a sample to a mass spectrometer is provided. The deposit reduction ionization source includes a heating vessel having a set of circulating hot gases to avoid any condensation formation within the volume of the vessel to maintain the vessel clean. The container has a tubular cross-section with a conduit attached to its side wall. The container is placed in front of the orifice of the curtain cone. An exhaust port is located on an opposite side of the conduit on the wall and proximate to the curtain cone. An atomizer is placed inside the conduit. Atomizing gas and auxiliary gas are introduced into the conduit and curtain gas is introduced into the curtain cone.

The present disclosure provides a method for determining the stability of a mass spectrometer and a method for testing the performance of a trace element analyzer.The procedure for the determination comprises: acquiring key performance parameters of the mass spectrometer to be evaluated; controlling the mass spectrometer to be evaluated to perform a performance test in order to obtain experimental data; performing a long-term state analysis based on the experimental data to obtain the statistical long-term state and the technical long-term state of individual key performance parameters, whereby the statistical long-term state characterizes whether the key performance parameter is in a controlled state within a specified time period, and the technical long-term state characterizes whether the key performance parameter lies within a specified parameter range within the specified time period; determining, based on the statistical long-term state and the technical long-term state, whether each of the key performance parameters meets a stability requirement.The method enables an accurate and efficient evaluation of the stability of a mass spectrometer's key performance during operation from two perspectives.

The utility model discloses a sample bearing device used for a mass spectrometer and a positioning target groove of the mass spectrometer, the sample bearing device is matched with the positioning target groove in the mass spectrometer for installation, the sample bearing device comprises a group of target point units, the target point units comprise a plurality of target points arranged at intervals along a first direction, the sample bearing device bears samples through the target points, and the target points are arranged at intervals along the first direction. The surface of the target spot is a hydrophilic surface and / or the surface of the sample bearing device around the target spot is a hydrophobic surface; only one group of target point units is arranged, and the target points on the target point units are arranged at intervals along the first direction, so that the device is suitable for users with small single detection quantity, and the ratio of the quantity of the target points containing samples on the sample bearing device to the total quantity of the target points during single-batch detection can be increased; therefore, the phenomenon that a user repeatedly scrubs the target plate due to the fact that many unused target spots are considered is avoided, the risk of cross contamination between the target spots is avoided, the influence on the detection quality of the next batch of samples is eliminated, and the accuracy of the sample detection result can be improved.

Provided herein is an ion source containing a plurality of components, at least one of which is partially coated with a layer of silicon. The ion source reduces reactivity between the sample and the c

A method of checking calibration of a dual-mode secondary electron multiplier (SEM) detector of a mass spectrometer using non-analyte ions, the method comprising: recording, using a counting mode dete