3 results about "Electron-capture dissociation" patented technology

An electron capture dissociation apparatus. The apparatus comprises a linear ion trap (3) consisting of an even number of strip electrodes (3.1), wherein an in-phase radio frequency voltage and an anti-phase radio frequency voltage are alternately applied to the strip electrodes (3.1) of the linear ion trap (3) in sequence, such that there is a saddle point potential at the central axis of an ion trapping space; and electrons emitted by an electron emission source (1) are accelerated by means of an accelerating electrode (2.1), are then focused by means of a focusing lens (2.2), and then enter the ion trapping space (3.2) through an electron introduction slot (3.3). The potential of the electron emission source (1) is set to change relative to the saddle point potential within a radio frequency cycle according to a predefined pattern, such that electrons enter the linear ion trap (3) through the electron introduction slot (3.3) when the radio frequency voltages on the strip electrodes (3.1) where the electron introduction slot (3.3) is located are in a positive half-cycle, and decelerate, before reaching the central axis of the ion trapping space (3.2), to an energy range where electron capture dissociation may occur, thereby improving the time window and dissociation efficiency of electron capture dissociation.

An apparatus comprising: an ion trap, for example a 2 dimensional, 2D, ion trap such as a linear quadrupole ion trap, LIT, wherein the ion trap comprises a set of electrodes, for example wherein the 2D ion trap comprises two or more pairs of rod electrodes and optionally two end electrodes; a power supply configured to: generate a substantially rectangular radio frequency, RF, voltage waveform, wherein the RF voltage waveform includes a first set of states including a first state having a first voltage level and a second state having a second voltage level, wherein the first state and the second state are mutually opposed; and apply the generated RF voltage waveform to the set of electrodes, wherein the first set of states provides a trapping field in the ion trap for trapping ions in a trapping region thereof; an electron source, configured to inject electrons into the ion trap for reactions thereof with the ions, for example electron capture dissociation, ECD, hot ECD, electron induced dissociation, EID, and / or electron detachment dissociation, EDD; wherein the RF voltage waveform includes a second set of states including a first state having a first voltage level, wherein the first voltage level of the second set of states is between the first voltage level and the second voltage level of the first set of states; and wherein the electron source is configured to inject the electrons into the ion trap during the second set of states, for example only during the second set of states.

An apparatus comprising: an ion trap, for example a 2 dimensional, 2D, ion trap such as a linear quadrupole ion trap, LIT, wherein the ion trap comprises a set of electrodes, for example wherein the 2D ion trap comprises two or more pairs of rod electrodes and optionally two end electrodes; a power supply configured to: generate a substantially rectangular radio frequency, RF, voltage waveform, wherein the RF voltage waveform includes a first set of states including a first state having a first voltage level and a second state having a second voltage level, wherein the first state and the second state are mutually opposed; and apply the generated RF voltage waveform to the set of electrodes, wherein the first set of states provides a trapping field in the ion trap for trapping ions in a trapping region thereof; an electron source, configured to inject electrons into the ion trap for reactions thereof with the ions, for example electron capture dissociation, ECD, hot ECD, electron induced dissociation, EID, and / or electron detachment dissociation, EDD; wherein the RF voltage waveform includes a second set of states including a first state having a first voltage level, wherein the first voltage level of the second set of states is between the first voltage level and the second voltage level of the first set of states; and wherein the electron source is configured to inject the electrons into the ion trap during the second set of states, for example only during the second set of states.