64results about "Electron/ion optical arrangements" patented technology

The present invention provides an ion detector that can suppress variations in ion detection time for ions with the same mass-to-charge ratio, and a mass spectrometer that can improve the resolution of mass spectrometry. [Solution] The ion detector 1A includes a conversion unit 2A that emits electrons e to the other side of direction D when ions i are incident from one side in direction D, and an output unit 3 that outputs an electrical signal in response to the incidence of electrons e emitted from the conversion unit 2A. The conversion unit 2A includes a support having a support surface perpendicular to direction D, and an electron generation layer disposed on the support surface that generates electrons e in response to the incidence of ions i. The support has a plurality of passages through which ions i or electrons e pass. The plurality of passages are arranged two-dimensionally along the support surface.

A radio frequency (RF) choke for use within a mass spectrometer comprises a bobbin having a hollow channel, a plurality of wire windings wound around the bobbin, each of the wire windings presenting a lattice winding pattern having a number of crossovers per turn of from about 1 to about 4, and a magnetic core disposed within the hollow channel of the bobbin. The RF choke exhibits an impedance in the range of from about 15 M ohms to about 150 M ohms with respect to an RF frequency generated by an RF voltage source within the range of from about 500 KHz to about 3 MHz, and a power dissipation equal to, or less than, about 3 W with respect to a peak-to-peak RF voltage of an RF voltage source of at least about 1 kV.

The present invention relates to an apparatus for analyzing peak data generated from a mass signal acquired by a mass spectrometry system, comprising: a streaming device including a first network interface and configured to (a) generate peak data from the acquired mass signal or receive peak data generated externally from the acquired mass signal, (b) group the peak data into a plurality of independently processable data packets, the data packets relating to a processing task, and (c) distribute the data packets as a task-specific stream onto a network via the first network interface; and at least one analysis device including a second network interface and configured to (a) retrieve data packets of a task-specific stream from the network via the second network interface, (b) perform a processing task on the retrieved data packets to generate result data, (c) encapsulate the result data in a result data packet, and (d) distribute the result data packet onto the network via the first network interface.

This invention relates to a high-efficiency ion current acquisition structure and a mass spectrometer. The ion current acquisition structure includes: a collection chamber adapted to be installed between the ion source and the sampling cone of the mass spectrometer; a trumpet-shaped aperture disposed within the collection chamber at the end facing the ion source; an annular electrode disposed on the inner wall of the trumpet-shaped aperture; and a beam rod assembly comprising multiple rod-shaped electrodes uniformly arranged circumferentially along the outlet of the trumpet-shaped aperture, with adjacent rod-shaped electrodes spaced apart to form gaps; wherein, on the side away from the ion source, the ends of the multiple rod-shaped electrodes are all bent and converged towards the central axis of the collection chamber. This invention provides a high-efficiency ion current acquisition structure that can improve the technical problems of low ion acquisition efficiency before entering the vacuum system and high background noise caused by the inability to effectively filter neutral particles in the prior art.

An amplifier arrangement for providing a variable electrode voltage to an ion optical device. The amplifier arrangement comprises a high speed amplifier designed to receive an input signal to the amplifier arrangement and provide a low voltage output, and a low speed adjustable voltage source arranged to float above the low voltage output and configured to provide a high voltage output of the amplifier arrangement. The high voltage output of the amplifier arrangement is fed back to control the high speed amplifier. Advantageously, the amplifier arrangement forms part of a power supply for providing a varying electrode voltage, for example as part of an ion analysis system.

An ion gate is provided for a mass spectrometer. A first electrode assembly comprises a plurality of guide electrodes arranged to define a multipole ion guide from a first end to a second end of the f

The present application provides a kind of ion spectrometer, it is related to the technical field of low energy ion detection in space, the ion spectrometer includes: energy spectrum screening device, by applying first electric field to multiple ion beams to be measured with different energy, so that multiple ion beams to be measured are deflected and allow target ions with predetermined energy range to exit, energy spectrum screening device includes: first shell;First pole plate is configured as arc and is installed to first shell, first pole plate and first shell are grounded;Second pole plate is electrically insulated and installed in first shell, is configured as arc concentric with first pole plate, by adjusting the voltage applied to second pole plate, variable first electric field is formed between second pole plate and first pole plate;Mass spectrum testing device, second electric field is applied to target ions, so that target ions are accelerated and keep uniform speed flight, to obtain the mass-to-charge ratio of multiple different ions based on the different flight time of multiple different ions in target ions, multiple different ions are separated.

The application belongs to the technical field of detection instruments, and provides an ion guiding device and a mass spectrometer, which comprise an electrode assembly and a support assembly, the electrode assembly comprises M electrode groups which are sequentially and spacedly distributed along a first direction and are sequentially recorded as a first electrode group to an Mth electrode group, each electrode group comprises first to fourth electrodes which are spaced from each other and are sequentially and rotationally symmetrically distributed around a central axis, the design has good ion confinement characteristics, can improve the mass discrimination problem of an ion funnel in a traditional mass spectrometer, the first to Mth central axes of the M electrode groups are located in the same plane, and the first central axis of the first electrode group and the Mth central axis of the Mth electrode group are arranged in a non-collinear manner, the sizes of the ith electrode group along a second and third direction are greater than or equal to the sizes of the ith+1 electrode group along the second and third direction, the first to third directions are perpendicular to each other in pairs, i is a positive integer less than M, and the off-axis transmission design realizes efficient separation of ions and pollutants and reduces instrument background noise.

The application provides an ion cyclotron resonance device for mass spectrometry, a control method and a mass spectrometer. The device comprises a cylindrical space region for ion introduction, excitation and detection. In the ion excitation process, the ions are excited radially outward from the center of the cylindrical space region. A pair of magnets are arranged axially parallel to the cylindrical space region for generating a magnetic field in the space region. The magnets have opposite polarities. The opposite surfaces of the magnets are perpendicular to the axial direction. The magnetic field intensity of the central region of the space region is greater than that of the outer peripheral region along the radial direction. An electrode array is arranged between the pair of magnets. An alternating voltage is applied to the electrodes of the electrode array for exciting the ions. The ion cyclotron resonance device can solve multiple problems such as device miniaturization, resolution, equipment and manufacturing cost.

Systems and methods are disclosed for ion injection into an electrostatic trap. Various aspects of this disclosure provide a mass spectrometer system including a primary ion path including a plurality of quadrupoles; and a secondary ion path coupled to the primary ion path utilizing turning elements. The secondary ion path may include an electrostatic linear ion trap (ELIT), the ELIT being operable to analyze ions diverted from the primary ion path and return them to the primary ion path. The primary ion path may include a time-of-flight mass analyzer. The secondary ion path may be bi-directional. Ions may travel in a first direction when coupled into the secondary ion path using a first turning element in the primary ion path and may travel in a second direction when coupled into the secondary ion path utilizing a second turning element in the primary ion path. The secondary ion path may include a collision quadrupole.

The present invention provides an ion detector that can suppress variations in ion detection time for ions with the same mass-to-charge ratio, and a mass spectrometer that can improve the resolution of mass spectrometry. [Solution] The ion detector 1A includes an incident electrode 20 which includes an incident section 21 through which ions i pass; a conversion electrode 30 which emits electrons e in response to the incidence of ions i that have passed through the incident section 21; an exit electrode 40 which is located on the incident electrode 20 side in the Z direction relative to the conversion electrode 30 and on one side in the X direction relative to the conversion electrode 30 and includes an exit section 41 which allows electrons e emitted from the conversion electrode 30 to pass through; and an electronic control electrode 90 which is located between the conversion electrode 30 and the exit section 41 in the Z direction and faces the conversion electrode 30 in the Z direction and includes a passing section 91 which allows ions i traveling from the incident electrode 20 to the conversion electrode 30 to pass through, and electrons e traveling from the conversion electrode 30 to the exit electrode 40 to pass through.

The application belongs to the technical field of mass spectrometers, in particular to a secondary ion extraction device for secondary ion mass spectrometry, which comprises a sample table, an extraction cone shell and a five-ring deceleration focusing system arranged in sequence from bottom to top, the extraction cone shell is internally provided with an ion extraction system, a sample is placed on the sample table, the ion extraction system comprises an extraction electrode, a front ground electrode, a single lens electrode and a rear ground electrode arranged in sequence from bottom to top, and each electrode is connected and separated by an insulating ring; the five-ring deceleration focusing system comprises a middle-aperture metal shielding shell, four ring electrodes and a differential electrode sheet arranged in sequence from bottom to top, and the four ring electrodes, the metal shielding shell and the ring electrodes, and the ring electrodes and the differential electrode sheet are connected and separated by insulating rings. The application can extract secondary ions from the surface of the sample, has a compact structure, a small volume and ensures optical microscopic imaging compatibility.

Apparatus and methods for performing charge detection mass spectrometry for measurement of the mass of a single ion of interest are disclosed. The ion of interest is caused to undergo harmonic oscillatory movement in the trapping field of an electrostatic trap, such that an image current detector generates a time-varying signal representative of the ion's oscillatory movement. This time-varying signal (transient) is processed (e.g., via a Fourier transform) to derive the ion's frequency and consequently determine the ion's mass-to-charge ratio (m / z). Ion charge is determined by construction of a Selective Temporal Overview of Resonant Ion (STORI) plot, which tracks the temporal evolution of signals attributable to the ion of interest, and where the slope of the STORI plot is related to the charge. The STORI plot may also be employed to identify ion decay events during transient acquisition and / or the presence of multiple ions of the same mass or non-resolvable ions.

An ion molecule reactor for generating analyte ions from analytes comprises:a) a reaction volume in which reagent ions can interact with the analytes in order to form analyte ions;b) at least one analyte inlet for introducing the analytes along an inlet path into the reaction volume whereby, preferably, the inlet path runs essentially along at least a first section of the predefined transit path in the reaction volume;c) at least one reagent ion source and / or at least one reagent ion inlet for providing reagent ions into the reaction volume;d) optionally, at least one ion guide comprising an electrode arrangement which is configured for producing an alternating electrical, magnetic and / or electromagnetic field, that allows for guiding the reagent ions and / or the analyte ions at least along a section of the predefined transit path, preferably along the whole transit path, through the reaction volume.

The invention relates to an electron imaging apparatus (23) configured to be connected to an energy analyzer apparatus. The electron imaging apparatus comprises a receiving aperture (22), a control unit, and a field generating unit (65). The receiving aperture is configured for receiving electrons from a focal volume (200) which form an electron beam (25). The control unit is configured for providing a control signal to the field generating unit based on a desired height of the electron beam in an energy dispersive direction (y) of the energy analyzer apparatus at a proximal end (90) of the electron imaging apparatus and a desired angular distribution (αp) in the energy dispersive direction at the proximal end. The field generating unit is configured for generating at least one electrostatic, magnetic, or electrostatic and magnetic field based on the at least one control signal such that the at least one electrostatic, magnetic, or electrostatic and magnetic field is configured for exerting a force on the electrons of the electron beam in the energy dispersive direction such that a height of the electron beam in the energy dispersive direction at the proximal end corresponds to the desired height in the energy dispersive direction at the proximal end and an angular distribution in the energy dispersive direction at the proximal end corresponds to the desired angular distribution in the energy dispersive direction at the proximal end.

The application discloses a kind of electrostatic field lossless ion manipulation structure's migration pipe and ion transmission method, belong to analytical detection technical field, the migration pipe includes multiple sets of annular reflection electrode, multiple sets of flat plate reflection electrode, multiple sets of ion straight line transmission electrode array, multiple sets of ion turning electrode array, multiple pieces of cylinder electrode, multiple pieces of mesh cylinder electrode, multiple pieces of rectangular flat plate electrode and multiple pieces of rectangular metal mesh electrode;Single set of annular reflection electrode includes a piece of cylinder electrode and a piece of mesh cylinder electrode;Single set of flat plate reflection electrode includes a piece of rectangular flat plate electrode and a piece of rectangular metal mesh electrode;Single set of ion straight line transmission electrode array is formed by multiple sets of annular reflection electrode;Single set of ion turning electrode array is formed by two sets of flat plate reflection electrode.The application can realize super-long ion migration path under electrostatic field, and there is important application value to the on-line separation detection of complex sample, even the identification of isomer.

Provided is a mass spectroscope capable of suppressing decreases in spectral sensitivity and resolution due to deformation during assembly of a multipole electrode. A mass spectroscope 28 comprises a multipole rod electrode 1 having a plurality of rod pairs (2A-1, 2A-2 ...). The rod pairs (2A-1, 2A-2 ...) are composed of pre-rods 2A-1 to 2D-1 and main rods 2A-2 to 2D-2 that are connected in the direction of an ion optical axis via an insulation member 6. In the multipole rod electrode 1, the pre-rods 2A-1 to 2D-1 constitute pre-rod electrode portions, and the main rods 2A-2 to 2D-2 constitute main rod electrode portions. The diameter of an inscribed circle 3 on which the pre-rod electrode portions 2A-1 to 2D-1 surround the ion optical axis is equal to the diameter of the inscribed circle 3 on which the main rod electrode portions surround the ion optical axis, and the diameter of all of the pre-rods 2A-1 to 2D-1 of the multipole rod electrode 1 is greater than the diameter of the main rods 2A-2 to 2D-2 connected to the pre-rods 2A-1 to 2D-1.

The sampling interface allows for sampling ions within the mass spectrometer for use in subsequent spectroscopic analysis. The sampling interface comprises an inlet for receiving a fixed amount of particles containing ions for spectroscopic analysis from an ion source; a skimmer located downstream of the inlet, having an opening through which particles from the inlet pass; an extraction lens located downstream of the skimmer, configured to extract ions from particles that have passed through the opening of the skimmer; an adjustable voltage source for applying a bias voltage to the extraction lens to generate an electric field in a region at least between the extraction lens and the skimmer; and a controller for controlling the adjustable voltage source to apply a bias voltage to the extraction lens in order to control the reduced electric field in the region directly downstream of the skimmer.

A mass analyzer is provided. The mass analyzer includes an ion source, a plurality of electrodes, a jitter compensation motor, and a voltage source. The ion source is configured to output ions along an ion trajectory. An ion detector is configured to detect the ions along the ion trajectory. The plurality of electrodes are arranged along the ion trajectory. Each electrode of the plurality of electrodes has an associated mass shift per volt perturbation. A jitter compensation electrode is disposed along the ion trajectory. The jitter compensation electrode and the plurality of electrodes are respectively connected to the voltage source. The jitter compensation electrode has a mass shift per volt perturbation configured to compensate for a net mass shift per volt perturbation of the plurality of electrodes.

A charge detection mass spectrometer (CDMS) is described, comprising an electrostatic sector field ion trap (40) and an induced charge detector (400), the electrostatic sector field ion trap (40) configured to at least partially define an ion path through the induced charge detector (400). A method is also described.

An ion optical element comprises: a plurality of rod electrodes, each having a convex portion formed at one end; a plurality of electrode members connected corresponding to each of the plurality of rod electrodes; and a non-conductive base member having a window portion through which ions pass, and fixing the plurality of electrode members and the plurality of rod electrodes at positions surrounding the window portion. Each of the plurality of electrode members has a through hole formed therein. The base member has a concave portion formed therein corresponding to the convex portion. The plurality of electrode members and the plurality of rod electrodes are positioned with respect to the base member by fitting the convex portion into the concave portion through the through hole.

Aspects of the present disclosure provide a method for operating an ion mobility spectrometer, the ion mobility spectrometer comprising an ionizer, a reaction region adjacent to the ionizer, a gate, and a detector for detecting the arrival of ions, the method comprising: (i) opening the gate for a first ion cloud entry time to allow a first group of sample ions to move from the reaction region through the gate to the detector in order to provide a first signal; (ii) opening the gate for a second ion cloud entry time to allow a second group of sample ions to move from the reaction region through the gate to the detector in order to provide a second signal, wherein during the second ion cloud entry time the gate is closed for a shutter time and then reopened; and (iii) determining the characteristics of the sample ions based on the first and second signals.

In one aspect, a mass spectrometer is disclosed, which comprises a Fourier Transform (FT) mass analyzer having an input port for receiving ions and an exit port through which the ions exit the FT mass analyzer, a detector disposed downstream of said FT analyzer for detecting ions exiting the FT analyzer, and a multi-segment ion guide having a plurality of segments, said multi-segment ion guide being disposed upstream of said FT mass analyzer and having an input port for receiving ions and an output port through which ions exit the FT mass analyzer. The segments of the ion guide are configured to be independently activated via application of a DC offset voltage thereto so as to adjust a length through which ions passing through the ion guide experience collisional cooling.

Provided is an ion optical element with high assembly accuracy and a mass spectrometer. The ion optical element includes a plurality of rod-shaped electrodes (43) each having a protrusion (43a) at one end, a plurality of electrode members (42) each connected to one of the plurality of rod-shaped electrodes (43), and a non-conductive base member (41) having a window portion (41a) through which ions pass and fixing the plurality of electrode members (42) and the plurality of rod-shaped electrodes (43) at positions around the window portion (41a). Each of the plurality of electrode members (42) has a through-hole (42a) formed therein. The base member (41) has a recess (41b) formed therein corresponding to the protrusion (43a). The plurality of electrode members (42) and the plurality of rod-shaped electrodes (43) are positioned relative to the base member (41) by fitting the protrusions (43a) into the recess (41b) with the protrusions (43a) passing through the through-holes (42a).

A method of separating ions comprising providing ions to an ion separation instrument having an ion attenuation region 22 arranged between first and second ion separator regions 20,24. The first ion separator region 20 is operated in an ion accumulation mode during which opposing forces are applied to the ions such that ions are caused to separate such that ions having mobilities above, or mass to charge ratios below, a first threshold value are urged into the ion attenuation region 22. The ion attenuation region 22 is operated in an attenuation mode, whilst the first ion separator region 20 is operating in the ion accumulation mode, so as to attenuate at least some of the ions that have been urged into the ion attenuation region.