1023results about "Electron/ion optical arrangements" patented technology

The invention discloses a self-constrained transverse extension ion optical lens device, and belongs to the technical field of cluster ion lens devices. The invention discloses a self-constrained transverse extension ion optical lens device which comprises a cuboid vacuum cavity and an ion lens device. The ion lens device comprises an entrance slit of an ion optical lens, an exit slit of the ion optical lens and an electrode group; the electrode group comprises a conical plate electrode group and a parallel plate electrode group; a crack at the head end of the conical plate electrode group forms an inlet slit of the ion optical lens, the tail end of the conical plate electrode group is connected with the head end of the parallel plate electrode group, and a crack at the tail end of the parallel plate electrode group forms an outlet slit of the ion optical lens; one side of the cuboid vacuum cavity is provided with a cluster beam generation device outlet, and the ion lens device is arranged in the cuboid vacuum cavity. Under the condition that the beam density in the prior art is kept unchanged, the cluster beam intensity entering and leaving the ion optical part is increased, and the cluster yield is improved.

The invention discloses a novel ion transmission focusing device, and belongs to the technical field of ion transmission. The flow limiting device comprises a flow limiting hole and an octupole rod device, each flow limiting hole is a metal plate with a small hole in the center, the two flow limiting holes form a vacuum differential cavity, and certain direct-current voltage is applied to the flow limiting holes. The octupole rod device comprises two insulating positioning rings and eight conical electrode rods which are arranged at equal intervals to form a cone shape, the eight conical electrode rods are fixed through the insulating positioning rings, and the two ends of the octupole rod are connected with an ion source outlet and a mass selector inlet respectively; every four adjacent electrodes are connected through a copper sheet to form two electrodes, and the two electrodes apply two radio frequency voltages with the same amplitude and opposite phases through a power supply. The ion transmission system can be used for focusing and transmission of cluster beams, and effectively improves the beam density in a low vacuum environment. The whole device is simple in structure, easy to machine and low in cost.

A method of separating ions based on mobility is provided. The method involves receiving ions by an ion mobility spectrometry device having a separation region, and causing the ions to travel through at least a portion of the separation region in a first direction along a path and separate based on ion mobility. The method further involves causing the separated ions to maintain a relative degree of separation therebetween and travel in a second direction along the path while maintaining the relative degree of separation therebetween. The second direction being opposite to the first direction. The ions are then caused to travel in the first direction along the path a second time to further separate the ions based on ion mobility. An ion mobility spectrometry device performing the foregoing method is also provided.

A method of calibrating a mass spectrometer 10 is provided. The method comprises generating calibration ions from an ion source 20. The calibration ions are transported from the ion source 20 to a mas

The invention belongs to the technical field of online analysis of organic pollutants, and particularly relates to a device and a method for real-time online analysis of non-volatile organic pollutants. The device comprises a sample injection module, a vacuum ultraviolet lamp, an ionization source cavity, a repulsion electrode, an ion funnel, a mass analyzer and a vacuumizing module, the ionization source cavity is provided with a sample injection port, a vacuum extraction port and an ion output port, and the vacuum ultraviolet lamp, the repulsion electrode and the ion funnel are sequentially arranged in the ionization source cavity at intervals in the axis direction of the ion output port; the ion funnel is close to the ion output port; the sample injection module is arranged at the sample injection port; the vacuumizing module is arranged on the vacuum extraction opening; the ion output port is externally connected with a mass analyzer; a direct-current voltage is applied to the repulsion electrode, and a direct-current voltage and a radio-frequency voltage are applied to the ion funnel. According to the invention, the ions with relatively large initial distribution area can be focused, so that the detection sensitivity is further improved, and the detection requirements on trace non-volatile organic pollutants are met.

Systems and methods described herein provide for charge state control of multiply-charged anions in a front end, high pressure ion guide. In some example aspects, a mass spectrometer system is provided comprising a first vacuum chamber (121) maintained at a pressure above about 500 mTorr. At least one ion guide (106) is disposed within the first vacuum chamber, the at least one ion guide comprising a plurality of rods extending along a central longitudinal axis. A controller (193) is configured to adjust an amplitude of an RF voltage signal provided to the plurality of rods so as to alternatively operate the ion guide in a first mode of operation with a lower amplitude of the RF voltage signal so as to reduce the likelihood of charge reduction by electron detachment so as to substantially maintain the isotopic distribution of the ions during transmission of ions through the ion guide, and a second mode of operation with a higher amplitude of the RF voltage signal so as to increase the likelihood of electron detachment from ions being transmitted therethrough.

Methods include introducing an ion quantity into an ion accumulation region, wherein the ion accumulation region, which can comprise a structure for lossless ion manipulations (SLIM) device allowing creation of a static or traveling wave electric field that moves ions towards an ion wall controllably blocking a movement of the ion quantity past the ion wall, wherein the ion wall is produced by one or more ion wall electrodes of an electrode arrangement, and directing the ion quantity in a direction towards the ion wall to increase a density of the ion quantity adjacent to the ion wall, such that the quantity of ions becomes space charge separated based on mobility along the direction and adjacent to the ion wall. Related apparatus provide space charge driven mobility separations.

The invention relates to the technical field of ion characterization and preparation, in particular to a high-throughput preparation mass spectrum device and method giving consideration to high-resolution characterization. The device comprises an ion source, an ion transmission cavity, a quadrupole mass screening cavity, an ion dissociation cavity, an ion deflection cavity, an ion deceleration and deposition cavity and a high-resolution mass spectrum characterization cavity which are sequentially arranged, wherein the high-resolution mass spectrum characterization cavity is formed in one side of the ion deflection cavity in the vertical direction; soft ionization is combined with a quadrupole analyzer to screen ions, the ions are dissociated through a dissociation cavity, an ion deflection cavity is used for selecting a high-resolution characterization or high-throughput preparation function, a high-resolution mass spectrum characterization cavity is used for achieving high-resolution characterization of screened and fragmented ions, and an ion deceleration and deposition cavity is used for high-throughput preparation of the ions. According to the method, perfect compatibility of high-throughput preparation and high-resolution mass spectrum characterization is realized through ion deflection design, and the method has a wide application prospect in the fields of efficient preparation of biological macromolecules, synthetic macromolecules and the like and the like.

An orthogonal acceleration time-of-flight mass spectrometer includes: a first vacuum chamber and a second vacuum chamber; an insulating spacer member; a former-stage-side ring electrode; subsequent-stage-side ring electrodes; a first fixation member including a first displacement member to displace a central axis of the former-stage-side ring electrode and the subsequent-stage-side ring electrodes in a predetermined direction orthogonal to the central axis by thermal expansion; and a second fixation member including a second displacement member to displace the central axis in the predetermined direction orthogonal to the central axis by thermal expansion, a difference between a thermal expansion amount of the first displacement member per unit temperature and a thermal expansion amount of the second displacement member per unit temperature being 30% or less of the thermal expansion amount of the first displacement member.

The invention relates to a continuous ion beam screening and enriching system and method and a mass spectrograph, and the continuous ion beam screening and enriching system comprises a vacuum differential unit, a first ion focusing unit, a mass screening unit, a second ion focusing unit, an enriching and releasing unit and a third ion focusing unit which are sequentially arranged from upstream to downstream. The enrichment and release unit is provided with a shell and a plurality of annular electrode plates which are arranged in parallel and located in a cavity of the shell, a resistor and a capacitor are connected between every two adjacent annular electrode plates to form a gradient electric field, and center holes of the annular electrode plates are concentrically arranged to jointly form an ion channel penetrating between an inlet and an outlet of the enrichment and release unit. According to the invention, continuous ion beam low-energy-consumption enrichment and pulse release can be realized, and strict requirements of scientific and industrial fields on mass spectrum detection and ion control precision are met.

Disclosed are methods, systems, apparatus, devices, and other implementations, that include a mass spectrometry (MS) system including a casing defining a cavity, a removable ion guide sub-assembly configured to be disposed within the cavity and including at least two mechanically coupled ion guides each defining a separate chamber at different pressures when engaged with the casing, with the removable ion guide sub-assembly including one or more insertion alignment elements to rotationally and / or angularly align the ion guide assembly for insertion into the cavity, and one or more receiving alignment elements disposed in the cavity and configured to receive a corresponding one of the one or more insertion alignment elements. The ion guide sub-assembly is configured to be axially removable from the casing with the at least two ion guides remaining mechanically coupled to each other and retaining the casing upon removal of the ion-guide sub-assembly from the casing.

The invention relates to the technical field of vacuum equipment, and discloses an ion lens assembly, an ion source, a mass spectrometer and a mass spectrometry system. The ion lens assembly includes a deflection lens assembly and a return lens assembly. The deflection lens assembly is used for focusing an ion beam in the incident particle beam and enabling the ion beam to deflect towards a first direction. And the axis-returning lens assembly is used for receiving the ion beam from the deflection lens assembly, and the axis-returning lens assembly is used for focusing the received ion beam and enabling the ion beam to deflect towards a second direction.

The invention belongs to the technical field of mass spectrum ionization sources, provides an online detection mass spectrum ionization source for gas components at an outlet of a combustion chamber of an aero-engine, and solves the problem that an existing ionization source is difficult to be applied to a field test for measuring the concentration of components at the outlet of a combustion chamber of a real aero-engine. According to the technical scheme, the device comprises an ionization source cavity and a radio frequency windowless discharge lamp, a plate electrode, a taper hole electrode, a lamp holder electrode, a direct current transmission electrode, a radio frequency transmission electrode and a differential electrode are sequentially arranged in the ionization source cavity in the axis direction, and a discharge gas inlet is formed in the ionization source cavity. One end of the radio frequency windowless discharge lamp is connected to the discharge gas inlet, and the other end of the radio frequency windowless discharge lamp extends into the lamp holder electrode; the taper hole electrode enables fuel gas to be fed in a molecular beam mode, efficient transmission of stable components and active components in the fuel gas is guaranteed, efficient transmission of ions is achieved in the mode that the direct-current transmission electrode and the radio-frequency transmission electrode are combined, and full-spectrum online analysis of the components of the fuel gas at the outlet of a combustion chamber of an aero-engine can be achieved.

A method and corresponding devices to reduce the presence of unwanted ions within the pseudo-potential well of the RF fields for inductively coupled plasma mass spectrometry is disclosed. This method reduces space-charge effects and leaves more room available for the ions of interest and, hence, leads to increased transmission of the desired ions into the mass analyzer. In the present invention, the space charge is reduced by adding a low-band resolving DC potential, or a fast sweeping resolving DC potential with a notch, or a fast constant resolving DC potential with a notch, or by adding auxiliary quadrupolar or dipolar RF potential to the quadrupole ion guide, such that all the unwanted ions will be outside the stable region and therefore ejected. This reduces the charge density in the ion beam and ameliorate space charge effects.

Disclosed are methods, systems, apparatus, devices, and other implementations, that include a mass spectrometry (MS) system including a casing defining a cavity, a removable ion guide sub-assembly configured to be disposed within the cavity and including at least two mechanically coupled ion guides each defining a separate chamber at different pressures when engaged with the casing, with the removable ion guide sub-assembly including one or more insertion alignment elements to rotationally and / or angularly align the ion guide assembly for insertion into the cavity, and one or more receiving alignment elements disposed in the cavity and configured to receive a corresponding one of the one or more insertion alignment elements. The ion guide sub-assembly is configured to be axially removable from the casing with the at least two ion guides remaining mechanically coupled to each other and retaining the casing upon removal of the ion-guide sub-assembly from the casing.

A mass spectrometry system that includes first and second ion sources that produce ions, the ions produced by the second ion source being calibration ions to calibrate the mass spectrometry system; an ion transfer device that receives the ions as a continuous stream during a first time period and forms a first ion packet as a single ion packet, such that during a second time period when the ion transfer device delivers the first ion packet, it receives the ions as a continuous stream to form a second ion packet by accumulating the incoming ions in another single ion packet, such that the ion transfer device separately delivers the formed ion packets at a frequency in a range from 1 to 1000 Hz; and a mass analyzer that separates the ions in the ion packets based on the mass-to-charge ratio of the ions.

A mass or mobility spectrometer comprising: a first vacuum chamber; and a collision cell arranged in the first vacuum chamber, wherein the collision cell comprises: an ion entrance at an upstream end thereof; an ion exit at a downstream end thereof; a main body portion between the ion entrance and ion exit; and an elongated tube between the main body portion and the ion exit. The collision cell comprises one or more ion guide extending through the main body portion, and / or through the elongated tube, for radially confining ions within the one or more ion guide. The spectrometer is configured to maintain the main body portion of the collision cell at a higher pressure than the first vacuum chamber; and the elongated tube is configured to limit the gas conductance out of the downstream end of the collision cell.

In one aspect, an ion guide assembly for use in a mass spectrometry system is disclosed, which comprises a first plurality of multipole rods that are arranged to allow passage of ions therebetween, a second plurality of multipole rods that are arranged to allow passage of ions therebetween, and a board disposed between the first and second plurality of rods, the board comprising an ion lens. The first and second plurality of rods are coupled to the board, and the rods of the first plurality of rods are pairwise aligned with, and coupled to, rods of the second plurality of rods.

The invention belongs to the technical field of mass spectrum analyzers, and particularly relates to an ion soft landing device for preparing a mass spectrometer through soft landing, an ion funnel, a grid mesh and a deposition target are all arranged in an ion deposition cavity and are sequentially arranged from left to right in the X direction, the ion funnel comprises eight or more than eight ion transmission electrodes, and the grid mesh is arranged in the ion deposition cavity. Each ion transmission electrode is of a flat plate structure with a through hole in the middle, the part, closest to the grid mesh, of the ion transmission electrodes is a small-hole electrode, and the through holes in the ion transmission electrodes form a horizontally and coaxially placed funnel-shaped ion transmission cavity; the ions entering the ion deposition cavity pass through the ion transmission cavity and can only pass through the through holes in the small-hole electrode to reach the grid mesh, and the ions decelerated by the grid mesh are deposited on the deposition target. According to the invention, the soft landing part of the soft landing preparative mass spectrum is reasonably designed, so that the purposes of large ion flow, efficient ion transmission and complete ion structure are achieved.

An array of identical linear quadrupole ion traps, each trap comprising the following: at least four main electrodes (32, 33, 34, 35) extending in a Z-direction to form a quadrupolar field at least in the midline region aligned along the Z-axis, wherein the Z-axis is either straight or curved with a radius that is substantially larger than the distance between the said main electrodes (32, 33, 34, 35); an ion ejection slot (36) in at least one of the main electrodes (32, 33, 34, 35); wherein the slot (36) is oriented in the Z direction; a pair of electrostatic end plugs (37, 38) arranged at the Z-edges of the quadrupole ion trap; wherein the pair of end plugs (37, 38) are a segment of the main electrodes (32, 33, 34, 35) or ring electrodes; an RF generator that provides RF signals with opposite phases, to form a quadrupolar RF field at least in the midline region of the main electrodes (32, 33, 34, 35); a variable DC supply for supplying DC signals to at least two rods in order to form a quadrupolar DC field with a weaker dipolar DC field at least in the midline region of main electrodes (32, 33, 34, 35); a DC, RF or AC supply connected to the aforementioned pair of end plugs (37, 38) to provide axial Z-capture; a gas supply or pumping means for providing a gas pressure in the range of 1 to 100 mTorr [0.133 to 13.332 Pascal], wherein the variable DC supply has means for ramping up the said quadrupolar potential, whereby a sequential ion ejection via the slot (36) occurs in the inverse relationship to the ion m / z, wherein the array further comprises a wide-diameter RF channel (25) with a DC gradient for collecting, transferring and spatially confining ions behind the slots (36) of the quadrupole ion traps; wherein the dimension of said RF channel (25) is defined by the trap sizes of the quadrupole ion traps and the topology of the array and the gas pressure in the quadrupole ion traps, and wherein the individual quadrupole ion traps are oriented such that an ion emission surface is formed which is either planar or at least partially cylindrical or partially spherical for more efficient collection and transfer of ions in the wide diameter RF channel (25).

A curved multipole collision reaction cell for an inductively coupled plasma mass spectrometer, comprising: a housing comprising a cell inlet, a cell outlet disposed opposite the cell inlet along a longitudinal axis of the housing, and a gas supply port in communication with an internal structure of the housing; and a curved multi-pole ion guide disposed inside the housing along a longitudinal axis of the housing, the curved multi-pole ion guide configured to generate an RF confinement field effective to constrain ions in a radial direction orthogonal to the longitudinal axis of the housing, while the curved multi-pole ion guide is disposed inside the housing along the longitudinal axis of the housing, and the curved multi-pole ion guide is configured to generate an RF confinement field effective to constrain ions in a radial direction orthogonal to the longitudinal axis of the housing. And separating neutral substances from photons and ions. In addition, by adopting the plasma mass spectrometry system of the collision reaction tank provided by the invention, the instrument volume of a mass spectrometer can be greatly reduced, and miniaturization is realized.

The invention relates to a mass spectrometry technology, and particularly provides an ion focusing method which comprises the following steps: (A1) ions sequentially pass through an incident lens, a multi-pole rod and an emergent lens; (A2) a compensation voltage E is obtained according to the mass and the charge number of the ions; and (A3) the compensation voltage E is applied to the incident lens and the emergent lens, and ions are focused at an inlet of the incident lens and an outlet of the emergent lens respectively. The invention has the advantages of good focusing effect and the like, and is applied to ion transmission.

A method and apparatus for ion storage are disclosed. The apparatus for ion storage includes multiple regions. A first region receives ions and transmits the ions to a second region using a first driving potential. The second region is switchable between a first state that generates a first electric field that prevents the ions from further moving into a third region and a second state that generates a second electric field that guides the ions toward the third region. In the first state, the ions are prevented from further movement by the first electric field and accumulate in the second region. In the second state, the ions are moved from the second region to the third region by the second electric field. A method for ion storage involves switching an electric field applied to the region between a trapping state and a releasing state.

The present invention relates to the technical field of geomagnetic activities, and in particular to an auroral substorm simulation method and macroscopic model based on neutral atom imaging measurement. The method includes the following steps: establishing a neutral atom imaging simulation equation for dynamic evolution of ion flux distribution of a ring current guided by ion pitch angle diffusion; and using the neutral atom imaging simulation equation, forward modeling neutral atom simulation images in an ecliptic plane corresponding to different ion pitch angle distribution functions during a geomagnetically quiet period and during an auroral substorm period to reproduce ring current ion flux distribution patterns in a growth phase stage and a recovery phase stage of an auroral substorm process. The present invention can emulate and reproduce ring current ion flux distribution patterns in a growth phase stage and a recovery phase stage of an auroral substorm process, which lays a foundation for further research.

Systems and methods are disclosed for dynamically switching an ion guide and a TOF mass analyzer between concentrating or not concentrating ions in a targeted acquisition. Product ions are ejected from the ion guide into the TOF mass analyzer and the intensity of a known product ion is measured at two or more time steps. The ion guide initially ejects product ions using a sequential or Zeno pulsing mode that concentrates product ions with different m / z values within the TOF mass analyzer at the same time. If the intensity of the product ion is increasing and greater than a threshold intensity, the ion guide switches to a continuous or normal pulsing mode that does not concentrate ions with different m / z values in the TOF mass analyzer at the same time. Similarly, if the intensity decreases below a threshold in continuous mode, the ion guide switches back to sequential mode.

The invention relates to a device for analyzing a biological sample, comprising: a sample stage; a charged particle source configured to deliver a charged particle beam to a location on the sample stage; and a first laser source and a first focusing optic configured to direct the laser beam emitted by the first laser source toward the sample stage, where the charged particle source, the first laser source, and the first focusing optic are configured such that the charged particle beam and the laser beam are directed toward opposite sides of the sample stage.

An apparatus for analyzing peak data generated from mass signals acquired by a mass spectrometric system comprises: a streaming device that comprises a first network interface and is configured to generate peak data from the mass signals or receive peak data generated externally from the mass signals, group the peak data into independently-processable data packets related to a processing task, and distribute the data packets in a task-specific stream via the first network interface onto a network; and at least one analyzing device that comprises a second network interface and is configured to retrieve a data packet of the task-specific stream via the second network interface from the network, perform the processing task on the retrieved data packet to produce result data, package the result data in a result data packet, and distribute the result data packet via the first network interface onto the network.

The invention belongs to the technical field of component detection, and relates to a three-state ion gate and a Hadamard transform ion mobility spectrometer. The three-state ion gate is arranged in the Hadamard transform ion mobility spectrometer and comprises a first grid mesh, a second grid mesh and a third grid mesh which are sequentially and separately arranged in the direction from a reaction region to a drift region; the grid voltage regulation and control module is used for controlling the voltage of the second grid to be larger than the voltage of the third grid and smaller than the voltage of the first grid within a first preset time when the modulation signal output by the spectral modulation Hadamard transform gating unit is a first level signal; when the modulation signal is converted from the first level signal to the second level signal, controlling the voltage of the second grid mesh to be greater than the voltage of the first grid mesh and the voltage of the third grid mesh within a second preset time; and when the modulation signal is a continuous second level signal, controlling the voltage of the second grid mesh to be smaller than the voltage of the first grid mesh and the third grid mesh. According to the scheme, the resolution and the signal-to-noise ratio of the ion mobility spectrometry obtained by the Hadamard transform example mobility spectrometer can be improved.

Disclosed herein is an ion guide for guiding an ion beam along an ion path, the ion guide having a longitudinal axis corresponding to the ion path. The ion guide includes a plurality of electrode plates arranged perpendicular to the longitudinal axis, each electrode plate having an opening and arranged so that the longitudinal axis extends through its respective opening, wherein the openings collectively define an ion guide volume. The ion guide extends or is configured to extend through a separation wall separating an adjacent first pumping chamber and a second pumping chamber. The ion guide has a first portion in which a gap is formed between at least some of the electrode plates so that uncharged gas can escape from the ion guide volume, wherein the first portion is entirely located in the first pumping chamber. A second portion prevents neutral gas from escaping from the ion guide volume between adjacent electrode plates, in which a sealing element is arranged between adjacent electrode plates, and the second portion extends at least from the separation wall into the second pumping chamber.

The invention relates to the technical field of analysis instrument ionization sources, in particular to a VUV lamp ionization source device with efficient heat dissipation capacity. The device comprises a VUV lamp, a heat dissipation unit, a VUV lamp driving electrode, a driving circuit and an ion guide focusing unit. The heat dissipation unit carries out cooperative heat dissipation on the VUV lamp and the pulse transformer through a fan, and the problems of signal attenuation and device aging caused by temperature rise are solved. The driving electrode adopts a pairwise pairing structure of upper and lower and left and right electrode pairs to form an inclined electric field to prevent ions from bombarding the lamp wall and the light window; the drive circuit is a half-bridge or full-bridge topology, can adjust the pulse frequency and the power supply voltage, and achieves the switching between a high-voltage low-frequency mode and a low-voltage high-frequency mode. The ion guide focusing unit efficiently leads out and separates ions through cooperation of a conical focusing electric field and a conductive film forward electric field. Through four-dimensional innovation of heat dissipation, electrodes, driving and transmission, the stability, the service life and the detection sensitivity of the device are improved, and the device is suitable for analytical instruments such as ion mobility spectrometry and mass spectrometry.