136 results about "Electrospray" patented technology

A plant holder for holding an amount of rooting (growing) media in which plant roots develop that electrically isolates the plant roots from an electric field used to deliver water and plant nutrients to that rooting media via a high-voltage, low-current electrospray system. A conductive material disposed proximate the rooting media receives electrically charged droplets including water or nutrients and passes the water or nutrients to the rooting media while directing the electrical charge to ground.

The invention provides an array type composite emitter ionic liquid electrospray thruster containing a far-end electrode, and relates to the technical field of spaceflight thrusters, an insulating material is adopted to process a composite emitter assembly, so that a double charge layer is generated at an ionic liquid electrode component, electrochemical reaction cannot be generated at an inner flow channel of a composite emitter, and the composite emitter assembly is made to be uniform. The problem that an electrochemical reaction product is directly generated in the composite emitter to block an internal flow channel of the emitter is avoided, and through the arrangement of a transverse flow channel, a vertical flow channel and a liquid collecting tank, a zigzag liquid flow channel is formed, so that the electrochemical reaction product generated at the electrode component is more uniform and uniform. When the ionic liquid flows, the ionic liquid is limited at the position of the electrode component by the flow channel wall surface and cannot enter the inlet of the base flow channel of the composite emitter assembly along with the ionic liquid, so that the influence of electrochemical reaction on the work of the composite emitter is prevented.

The invention belongs to the technical field of detection methods, and particularly relates to a liquid chromatography detection method for an idedecalciferol intermediate and impurities thereof. According to the liquid chromatography detection method for the eldecalciferol intermediate and the impurities thereof, a liquid chromatography method is combined with an electrospray detector for detection; chromatographic conditions are as follows: an amylose-tri (3-chlorphenyl carbamate) covalently bonded silica gel chromatographic column is adopted; and carrying out gradient elution by taking water as a mobile phase A and acetonitrile as a mobile phase B. The method for detecting the eldecalciferol intermediate and the impurities of the eldecalciferol intermediate is good in specificity, high in sensitivity and accuracy, good in repeatability and stability and high in analysis speed, the content of the eldecalciferol intermediate and the impurities of the eldecalciferol intermediate can be rapidly and accurately detected, and the blank of detection of the eldecalciferol intermediate and the impurities of the eldecalciferol intermediate in the prior art is filled.

The invention relates to the technical field of food safety detection, in particular to a method for detecting urea in bean sprouts and application thereof.The method comprises the following steps that smashed bean sprouts are subjected to two times of ultrasonic extraction and centrifugation, supernate is combined, and an extracting solution is obtained; fixing the volume and filtering to obtain a to-be-detected solution; detecting the liquid to be detected by using liquid chromatography-tandem mass spectrometry; an extraction solvent for ultrasonic extraction is a 5% formic acid-acetonitrile composite solution; the conditions of the liquid chromatography-tandem mass spectrometry are as follows: the chromatographic conditions are as follows: a chromatographic column is an HILIC column; the sample size is 10 [mu] L; a mobile phase is a mixed solution of a 0.02 mmol / L ammonium acetate buffer salt solution and acetonitrile, and isocratic elution is carried out; the flow rate is 0.3 mL / min; the column temperature is 40 DEG C; mass spectrum conditions are as follows: an electrospray ionization (ESI) positive ion mode, electrospray voltage of 4000 V, sheath gas pressure of 30 psi, auxiliary gas pressure of 5 psi, capillary heating temperature of 300 DEG C and scanning mode of MRM. The method disclosed by the invention is free from substance interference, high in sensitivity, accurate in result, low in cost and high in efficiency, and can be used as a standard detection method.

The present application relates to the technical field of microsphere preparation, and particularly relates to a microsphere-based electrospray device, which comprises a nozzle, a conductive piece and a power supply, the nozzle has a solution channel, the solution channel has an inlet and an outlet, the conductive piece is arranged at a position adjacent to the outlet, the power supply comprises a first output end and a second output end, the first output end is connected with the outlet to provide a first electric field, the second output end is connected with the conductive piece to provide a second electric field, and the direction of the first electric field is arranged orthogonally to the direction of the second electric field, the microsphere-based electrospray device can improve the uniformity of the prepared microspheres.

The application provides a kind of ionic liquid electric spray micro force calculation method, device and electronic equipment, it is related to data processing field, the method is carried out original molecular dynamics simulation in the negative gradient calculation of position to atomic potential energy and obtains the force model, the micro force decoupling of ionic liquid electric spray under molecular dynamics simulation is executed;Based on the micro force model, the molecular dynamics trajectory data is recalculated by modifying the molecular dynamics simulation code parameters, the pre-data of different micro forces is obtained, and the atomic force calculation result is output based on the pre-data of different micro forces;The atomic force calculation result corresponding to the steady state part of system is calculated by time and space average, and the spatial distribution calculation result of micro force and electric field is obtained;After a spatially uniform distribution of constant electric field is applied to the system, the first external electric field received by the charged atom is calculated using the above scheme, and the applied electric field and the calculated electric field are consistent, which verifies that the scheme is executed without error.

The application discloses a capillary type ion liquid electric spray thruster with electrically controlled thrust, and belongs to the technical field of micro-nano satellite micro propulsion. The application comprises a propellant tank, an upper shell, a constant force spring, a limiting plate, a capillary and an extraction electrode. The inner and outer walls of the capillary are covered with a dielectric layer with a micron level thickness, and the inner wall is covered with a hydrophobic layer with a nanometer level thickness. The extraction electrode is fixed through an insulating screw; and the upper shell is fixed with the propellant tank. The application is based on the principle of electric wetting, uses an electric field to control the active supply of ion liquid and simultaneously adjusts the thrust size of the thruster. The application can not only save complicated fluid control components such as high-precision pumps, valves and pipelines, but also can couple the supply process and the emission process of the ion liquid, simplify the operation process of the thruster system and facilitate the miniaturization of the thruster system. The application is suitable for resistance compensation, position keeping and attitude control of low-power micro-nano satellites.

The invention discloses a precise adjustable electrospray thruster device which is characterized in that an emitter mounting bracket is used for fixing a porous ceramic emitter, and the fixed porous ceramic emitter can move along with the mounting bracket; the special-shaped groove in the mounting bracket is used for quickly positioning the mounting bracket; the fine adjustment of the relative position between the porous ceramic emitting electrode and the extraction electrode can be realized by adjusting a spring jackscrew in a horizontal plane and a fastening screw in a vertical plane; the fine adjustment process can be operated under a microscope to improve the adjustment precision; the shell of the electrospray thruster is designed to be of a spiral twenty-four-face structure and is machined and formed through the 3D printing technology, and the weight of shell parts is further reduced by designing a hollow cavity in the shell.

The application provides a detection method of hydroxypropyl cellulose in a povidone-containing preparation, and specifically comprises the following steps: (1) preparing a sample solution by pretreating a sample to be detected; (2) detecting the sample solution by using HPLC, wherein an evaporative light scattering detector or an electrospray detector is used as a detector, a C18 chromatographic column is used as a chromatographic column, the column temperature is 20-40 DEG C, water is used as a mobile phase A, methanol is used as a mobile phase B, the flow rate is 0.5 ml / min-1.5 ml / min, and gradient elution is adopted. The detection method has good specificity and peak type, can not only separate hydroxypropyl cellulose from povidone and other high-molecular auxiliary materials in a pharmaceutical preparation, accurately quantify the content of hydroxypropyl cellulose, but also effectively identify the model, and provides a good method for reverse analysis, component analysis, auxiliary material release detection of the pharmaceutical preparation.

The invention discloses a plasma electrospray fusion ionization source and mass spectrum combined system and a detection method. The plasma electrospray fusion ionization source and mass spectrum combined system comprises a coaxially nested electrospray needle, a sample injector, an ultrahigh voltage generator, a grounded metal grid mesh, a mass spectrometer and a detector thereof. A grounded metal grid is installed between a spray needle and a mass spectrum inlet, voltage is applied to the spray needle, carrier gas is excited to generate plasmas, the macroscopic plasmas at the front end of the spray needle are fused with electrospray, and the plasmas and micro-droplets at the tip of the spray needle are fused. According to the unique ionization source constructed by the plasma-micro-droplet fusion system, on one hand, the ionization efficiency is improved, mass spectrum signals are enhanced, the application range of analytes is widened, excellent sensitivity to high-polarity compounds is kept, and effective ionization and detection of low-polarity compounds are achieved; on the other hand, higher energy and active species are provided for the micro-droplet reaction, the energy barrier required by traditional synthesis is broken, and efficient spontaneous product generation of the micro-droplet chemical reaction is achieved.

The present application belongs to the technical field of curved surface electronic Wiener manufacturing, and discloses an insulating surface electroblotting device and method based on real-time plasma processing, which comprises an electroblotting assembly and a plasma assembly, wherein the electroblotting assembly and the plasma assembly work synchronously; the electroblotting assembly is used for conveying ink to a nozzle to form a jetting jet; the plasma assembly is used for processing an insulating surface by adopting a ring-shaped plasma beam to inject a polarized group into the insulating surface, and the polarized group generates a negative polarity charge under the action of an electroblotting electric field, and at the same time, residual charges of ink liquid and polarized charges of the insulating surface are neutralized to realize stable jetting and deposition of ink jets / drops on the insulating surface. The present application solves the printing and forming problem of a complex microstructure of an insulating substrate.

The invention relates to the technical field of tobacco chemical analysis, in particular to a multistage mass spectrometry identification method for chemical structures of sucrose esters in tobacco and tobacco products, which comprises the following steps: crushing and extracting a tobacco product sample; carrying out solid-liquid separation and filtration to obtain a liquid to be detected; separating the liquid to be detected by adopting hydrophilic interaction chromatography; performing triple quadrupole-ion trap tandem mass spectrometry analysis on the components separated in the step S2 by adopting an electrospray ion source in a positive ion mode to sequentially obtain mass spectrometry information of parent ions, daughter ions and grandchild ions; and determining the chemical structure of the sucrose ester based on the mass spectrum information of the parent ion, the daughter ion and the grandchild ion measured in the step S3. According to the method, complex pretreatment steps are not needed, sucrose esters with different configurations can be identified more efficiently, interference can be effectively eliminated, and substituent group structure information of a low-content target object can be scientifically confirmed.

The invention relates to a qualitative and quantitative method for detecting active ingredients of root-strengthening and cough-relieving granules through UPLC-MS / MS, and belongs to the technical field of medicine analysis and detection. The four active ingredients of liquiritigenin, isoliquiritigenin, luteolin and bakuchiol in a sample can be detected at the same time. The method comprises the following steps: pretreating a sample by a 70% methanol ultrasonic extraction method to obtain a target sample solution, and detecting by using an SCIEX ExionLC AE high-pressure liquid phase system and an AB SCIEX 4500 mass spectrometer in combination with an MRM mode. Carrying out gradient elution on a liquid phase by using an HSS T3 C18 chromatographic column and 0.1% formic acid water-acetonitrile as a mobile phase; the mass spectrum is electrospray negative ion scanning, and a specific ion source and MRM parameters are set. The method can rapidly separate the four components, is short in detection period, high in sensitivity and strong in matrix interference resistance, can be accurately qualitative and quantitative, and provides support for preparation quality evaluation, pharmacodynamic mechanism research and clinical reasonable medication.

Disclosed is an electrospray probe for an electrospray ion source, the electrospray probe comprising a sleeve extending from a proximal end having an inlet aperture for receiving a liquid sample containing at least one analyte to a discharge emitter end having an outlet aperture through which charged droplets containing ions of the analyte are discharged, and a conductive coating covering at least a portion of an outer surface and at least a portion of an inner surface of the emitter end.

The invention belongs to the technical field of vitamin content detection, and particularly relates to a method for measuring the content of various water-soluble vitamins B. The water-soluble vitamins B comprise vitamin B1, vitamin B2, vitamin B3, vitamin B6, vitamin B7, vitamin B12 and nicotinamide. A high performance liquid chromatograph and an electrospray detector are used as detection instruments, and chromatographic conditions are as follows: a mobile phase A is ammonium formate or ammonium acetate, a mobile phase B is methanol, and gradient elution is performed; the gradient elution procedure is as follows: a solvent of a test sample is a mixed solution of acetonitrile, water and glacial acetic acid, and the volume ratio of the acetonitrile to the water to the glacial acetic acid is 5: 95: 0.5; the atomization temperature of the electrospray detector is 35 DEG C; the method is better in separation degree and higher in specificity and sensitivity.

A method is disclosed comprising providing a biological sample on a swab, directing a spray of charged droplets onto a surface of the swab in order to generate a plurality of analyte ions, and analysing the analyte ions.

The application belongs to the field of advanced manufacturing technology, and proposes a micro-nano electro-fluid jet printing method based on electric field focusing and deflection control. The method uses double circular rings as induction electrodes to induce the printing of charged droplets with micro-nano scale resolution at the metal micro-tip of the ink, and then uses the time-varying pulse voltage signal generated by the jet deflection electrode to control the flight trajectory of the droplets, so as to print high-precision micron patterns on the stationary receiving plate. Combined with the movement of the work platform, macro-scale structures can be further manufactured. The method breaks through the limitation that the trajectory movement of the work platform is necessary for the electro-fluid jet printing of micron patterned structures, and can realize the deposition of any pattern on a stationary platform, and has the characteristics of high printing resolution, high precision and high efficiency.

The invention discloses a lithium manganate positive electrode material, a preparation method and an applied lead-lithium battery, relates to the technical field of lithium manganate positive electrode materials, and solves the problems that the existing lithium manganate positive electrode material is poor in structure and interface stability and poor in rate and cycle performance. The positive electrode material is composed of a lithium manganate matrix and a double-layer composite coating, the matrix is prepared by taking lithium carbonate and manganous-manganic oxide as raw materials and doping magnesium hydroxide, aluminum hydroxide and titanium dioxide multi-plasma phase; the lithium manganate positive electrode material is prepared by uniformly compounding a lithium manganate matrix modified by a spinel inner layer, vinyl functionalized MOF and a polyvinylidene fluoride-hexafluoropropylene copolymer on the surface of an aluminum foil receiver through an electrospinning-electrospray synergistic process. The material is applied to the lead-lithium battery, shows excellent electrochemical performance and has good practical application value.

The application discloses a single-cell online prolonging lysis mass spectrometry flow analysis method. A cell suspension sample is injected into a separation capillary, a front section of the capillary is spirally wound to realize single dispersion of the cells, and a part of a rear section of the capillary is located in an ultrasonic device to realize online ultrasonic lysis, localized single-cell lysis contents are obtained, the content solution gradually enters a non-contact electrospray needle to realize ionization, and finally enters a mass spectrometry detector for detection. Meanwhile, the analysis coverage of weakly polar compounds can be improved by combining a plasma generation device. The method can realize single-cell analysis with high throughput and high metabolite coverage, and by means of a prolonged single-cell detection window, the collection of metabolite primary mass-to-charge ratio information and the identification of secondary structures under high resolution can be realized, including qualitative and quantitative analysis of positional isomers, so that the method has wide application prospects in the fields of cell identification, cell typing, differential substance research, tumor diagnosis and biomarker mining.

The application discloses a low-cost electrospray device for capturing nanoparticles in a vacuum system, which comprises a micro-injection pump, a stainless steel capillary, a high-voltage direct-current power supply and a vacuum cavity. The micro-injection pump is used to slowly extrude a syringe to provide a stable flow rate of a nanoparticle solution for the device. A conductive wire is connected to the liquid through a PEEK tee connector to charge the liquid. The vacuum cavity is located behind the electrospray and has a pressure lower than the atmospheric pressure. The charged liquid is attracted by a grounded metal ring after flowing out of the stainless steel capillary, breaks through the surface tension and forms a uniform spray to pass through the middle of the grounded metal ring. The electrospray is sucked into the vacuum cavity due to the pressure difference. A quadrupole rod is arranged in the vacuum cavity to guide and store the nanoparticles. The device can form a stable and continuous nanoparticle electrospray by providing a lower voltage, so as to realize the loading of the nanoparticles in the vacuum.

The invention provides an ionic liquid electrospray microcosmic stress calculation method and device and electronic equipment, and relates to the field of data processing.The method comprises the steps that negative gradient calculation of the position of atomic potential energy is conducted to obtain an acting force model in original molecular dynamics simulation, and microcosmic acting force decoupling of ionic liquid electrospray under molecular dynamics simulation is executed; re-calculating the molecular dynamics trajectory data by modifying molecular dynamics simulation code parameters based on the microscopic acting force model to obtain preposed data of different microscopic acting forces, and outputting atomic acting force calculation results based on the preposed data of the different microscopic acting forces; carrying out time and space average calculation on the atomic acting force calculation result corresponding to the steady-state part of the system to obtain a microscopic acting force and an electric field space distribution calculation result; after a constant electric field which is uniformly distributed in space is applied to the system, the first external electric field borne by the charged atoms is calculated by using the scheme, and if the applied electric field is consistent with the calculated electric field, the scheme execution is correct.

The present disclosure relates to integrated electrospray emitters and methods of manufacturing the same. An electrospray ionization emitter according to various aspects described herein can include an emitter body formed using fused silica. The emitter body can include a fluid conduit segment including a liquid connection end that has been coated with polyether ether ketone (PEEK) over at least a portion of the liquid connection end. The liquid connection end can have a first outer diameter configured to connect to a sample source to receive a sample liquid for ionization from the sample source. The emitter body can also include an ionization discharge segment fluidically connected to the fluid conduit segment. The ionization discharge segment can have an ionization discharge end coated with a conductive material over at least a portion of the ionization discharge end and configured to have a second outer diameter that allows for ionization of the liquid sample.

The application discloses an electrospray detector, which comprises a first air inlet pipe, a second air inlet pipe, a discharge chamber, an atomization chamber, a drift tube, a mixing chamber, a waste liquid pipe, a waste liquid bottle, a migration pipe, a particle removal trap and a collection device. The air inlet of the second air inlet pipe is communicated with the pipe body of the first air inlet pipe; the discharge chamber is communicated with the second air inlet pipe; the atomization chamber is communicated with the first air inlet pipe; the drift tube is formed in a straight cylinder shape; the drift tube is communicated with the atomization chamber; the mixing chamber is communicated with the drift tube and the discharge chamber; the waste liquid pipe is communicated with the mixing chamber; the liquid outlet of the waste liquid pipe is communicated with the waste liquid bottle; the migration pipe is communicated with the mixing chamber; the migration pipe is formed in a straight cylinder shape; the migration pipe and the drift tube are located on the same axis; the particle removal trap is arranged in the migration pipe; and the collection device is communicated with the migration pipe. The drift tube and the migration pipe of the electrospray detector are both in a straight cylinder shape, so that the sample does not collide with the pipe wall, the loss of the sample is avoided, the detection precision is improved, and the pollution to the pipe wall is reduced.

The present invention provides a method for quantitatively detecting the blood-transmitting components of Toad Venenum or Salvia miltiorrhiza in Musk Tongxin Dropping Pills, specifically comprising ultra-high performance liquid chromatography-tandem mass spectrometry detection of drug-containing plasma or tissue. The liquid chromatography conditions employ a C18-filled column, mobile phase A consisting of 0.05% to 0.2% formic acid in water, mobile phase B consisting of 0.05% to 0.2% formic acid in acetonitrile, and gradient elution; an electrospray ion source in positive ion mode, a drying gas temperature of 300 to 400°C, a drying gas flow rate of 4 to 8 L / min, a sheath gas temperature of 300 to 400°C, a sheath gas flow rate of 8 to 12 L / min, and a nebulizing gas pressure of 40 to 50 psi; a capillary inlet voltage of 3 to 4 kV; a cone voltage of 450 to 550 V, a collision energy of 10 to 30 eV, and a fragmentation voltage of 100 to 190 V. The present invention can simultaneously and quantitatively detect 9 kinds of toad venom components and 3 kinds of salvia miltiorrhiza components entering the blood in Musk Tongxin Dropping Pills, and has high detection sensitivity, good stability and short detection time, and is suitable for the pharmacokinetic study of Musk Tongxin Dropping Pills.

The application discloses an electric spray thruster, relates to the technical field of electric thrusters, and can quickly position an emitter and an extraction grid, saves the mounting time of the thruster, and improves the consistency of the positions of the emitter and the extraction grid. The electric spray thruster comprises a shell, an emitter, a high-voltage electrode and an extraction grid, the shell has a containing cavity for containing propellant, and the inner wall of the shell is provided with a first limiting surface. The emitter is arranged in the containing cavity, and one end of the emitter is located below the liquid level of the propellant. The high-voltage electrode is fixedly sleeved outside the emitter, and the high-voltage electrode is arranged on the inner wall of the shell. The outer wall of the high-voltage electrode is provided with a second limiting surface which is limitedly matched with the first limiting surface and is used for limiting the relative position of the high-voltage electrode and the shell. The extraction grid is arranged at the outlet end of the shell, and one side of the extraction grid close to the containing cavity is provided with a protruding portion which extends into the containing cavity, the protruding portion is provided with a third limiting surface which is limitedly matched with the first limiting surface and is used for limiting the relative position of the extraction grid and the shell.

Self-limiting electrospray compositions including a non-charge-dissipative component and / or a charge-dissipative component. Self-limiting electrospray composition including a plurality of charge-dissipative components and excluding a non-charge-dissipative component. Methods for forming layers of self-limiting thickness. Methods for determining a conductivity of a material. Methods for repairing a flaw in a layer on a surface of an object.

This invention proposes a polybenzimidazole microporous ion-conducting membrane and its one-step electrospray preparation method. Polybenzimidazole electrospray solutions are prepared using organic solvents with different boiling points. Electrospray parameters are adjusted under a high-voltage electrostatic field, and the polybenzimidazole electrospray solution is dispersed into nanodroplets using this field. A receiving roller rotates to spread and layer the droplets, followed by rapid drying and solidification, directly preparing the polybenzimidazole microporous membrane. This invention can directly prepare microporous membranes using non-ionic polymer materials, and the membrane preparation process is simple and easily scaled up. It overcomes the problem of high mass transfer resistance of non-ionic polymers, enabling highly selective proton conduction. Simultaneously, the high stability of non-ionic polymers improves the oxidative stability and mechanical strength of the ion-conducting membrane, showing broad application prospects in the field of new energy storage flow batteries.

The utility model provides an electrospray ionization device based on ozone gaseous derivative ionization, which comprises a device for supplying ozone to a mass spectrum ion source and the mass spectrum ion source, and the mass spectrum ion source comprises an ion source and an ion inlet device, the apparatus for supplying ozone to a mass spectrum ion source includes an oxygen supply device and an ozone generator, oxygen is supplied into the ozone generator through the oxygen supply device, ozone is generated, and the apparatus for supplying ozone to a mass spectrum ion source supplies the generated ozone to an ion source.

The application provides a lung cancer intelligent screening model construction method and system based on sputum direct mass spectrum data. The method comprises the following steps: S1, obtaining the original mass spectrum data of the sputum sample detected by neutral desorption electrospray extraction ionization mass spectrometry, preprocessing including mass spectrum peak detection, peak alignment and intensity normalization to form an initial feature matrix; S2, extracting a core metabolic fingerprint feature set from the initial feature matrix; S3, constructing and training a heterogeneous integrated diagnosis model; S4, optimizing and verifying the hyperparameters of the heterogeneous integrated diagnosis model, and packaging the optimized heterogeneous integrated diagnosis model and the screening rules of the core metabolic fingerprint feature set into a lung cancer screening deployment module. The application realizes high-robustness, high-precision and high-explainability lung cancer non-invasive intelligent screening.