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4 results about "Electrospray ionization" patented technology
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Electrospray ionization (ESI) is a technique used in mass spectrometry to produce ions using an electrospray in which a high voltage is applied to a liquid to create an aerosol. It is especially useful in producing ions from macromolecules because it overcomes the propensity of these molecules to fragment when ionized. ESI is different from other ionization processes (e.g. matrix-assisted laser desorption/ionization (MALDI)) since it may produce multiple-charged ions, effectively extending the mass range of the analyser to accommodate the kDa-MDa orders of magnitude observed in proteins and their associated polypeptide fragments.
Sample pretreatment method for desorption electrospray ionization mass spectrometry imaging of biological tissue frozen section
PendingCN121499177APreparing sample for investigationMaterial analysis by electric/magnetic meansIntracellularElectrospray ionization
The invention relates to a sample pretreatment method for desorption electrospray ionization mass spectrometry imaging of a biological tissue frozen section, and the method comprises the following steps: pre-spraying the surface of the frozen biological tissue section, a pre-spraying solvent being a histocompatible solvent, and being used for enhancing the extraction of components in biological tissue cells, the detection sensitivity of components in biological tissues, especially in cells, is improved.
Owner:SHANGHAI INSTITUTE OF MATERIA MEDICA CHINESE ACADEMY OF SCIENCES
Desorption electrospray ionization imaging source
1. The name of the design product: desorption electrospray ionization imaging source. 2. The use of the design product: a desorption electrospray ionization imaging source, which makes the analyte desorb and ionize by spraying solvent to bombard the sample surface, and is used for mass spectrometric analysis of substances. 3. The design points of the design product: in shape. 4. The picture or photo that best indicates the design points: perspective view.
Owner:JIANGSU PUCE SCI INSTR CO LTD
apparatus
PCT designated stageWO2026037501A1Electron/ion optical arrangementsDispersed particle separationPhysical chemistryElectrospray ionization
An apparatus for ion analysis or an Electrospray Ionisation, ESI, interfacing apparatus comprising a virtual impactor comprising a minor flow part configured for directing towards a downstream region a part of a received flow of a gas entrained with ions as a minor flow of the gas containing at least a majority of the ions. A major flow part is configured for directing away from the downstream region a part of the received flow of gas as a major flow of the gas containing not more than a minority of the ions.
Owner:SHIMADZU CORP +1
High-throughput label-free enzymatic bioassays using automated DESI-ms
PendingUS20260098832A1Compound screeningApoptosis detectionBiologic AssaysMass Spectrometry-Mass Spectrometry
The invention generally relates to high-throughput label-free enzymatic bioassays using desorption electrospray ionization-mass spectrometry (DESI-MS).
Owner:PURDUE RES FOUND