4 results about "Clenbuterol" patented technology

The application discloses a method for detecting clenbuterol based on thin layer chromatography and surface enhanced resonance Raman spectroscopy, and belongs to the technical field of food detection. The method comprises the following steps: (1) adopting thin layer chromatography to preliminarily separate the clenbuterol component from the matrix in the pig liver sample, and confirming the clenbuterol component in the pig liver sample under the ultraviolet lamp of 254 nm; (2) adding aromatic diazonium salt solution to the same Rf value of the clenbuterol component reference sample spot to generate azo compounds, and then adding a surface enhancer silver sol; (3) in-situ detecting the surface enhanced resonance Raman spectrum of the corresponding azo compound component spot, and if the surface enhanced resonance Raman spectrum of the pig liver sample solution at the same Rf value is the same as that of the reference sample solution, it is determined that the pig liver sample contains the clenbuterol component. The application has high specificity for detecting clenbuterol and salbutamol, high sensitivity, fast analysis speed, and is beneficial to fast detection of grass-roots units. The application is suitable for detecting clenbuterol.

The invention relates to an intelligent clenbuterol concentration mapping method based on Raman scattering space-time dynamic attenuation characteristics. According to the method, based on theoretical models of molecular dynamics and statistical physics, frequency-domain spectral information is inverted to a time-domain coherence function, a clenbuterol molecule'free state-cluster state 'double-pool dynamic model is established, and internal correlation between concentration and molecule aggregation state and coherence attenuation is revealed for the first time; abnormal samples can be automatically identified in detection of clenbuterol, and a quality scoring mechanism is provided; compared with traditional Raman spectrum detection, the sensitivity and the measuring range of the method are remarkably improved, the detection limit is reduced to 0.42 mu g / kg from 10-50 mu g / kg and is improved by 20-100 times, and the national standard requirement (1t, 0.5 mu g / kg) is met; the linear range of the measuring range is expanded from 1-2 orders of magnitude to 3-4 orders of magnitude (0.5-500 [mu] g / kg), and a high-residue full scene is covered by trace detection; the method can also be expanded to detection of other small molecules and does not depend on specific chemical properties of substances.

The application provides a high-sensitivity detection method for multi-residues of veterinary drugs in pig urine, and belongs to the technical field of detection of veterinary drug residues. The application first performs enzymatic treatment on the sample to be detected, thereby improving the detection sensitivity of salbutamol and ractopamine; then performs acid hydrolysis and derivatization treatment on the sample to be detected, thereby improving the reversed-phase chromatographic retention performance and mass spectrometry ionization efficiency of nitrofurans in the compound to be detected, improving the sensitivity, improving the polarity of the compound to be detected, thereby improving the chromatographic separation effect, effectively separating the interfering substances in the matrix, improving the anti-interference ability of the detected substance, and indirectly improving the detection sensitivity; clenbuterol, metronidazole, dimetridazole, olaquindox, chlorpromazine and chloramphenicol are mainly in free state, and are not affected by enzymatic and acid hydrolysis and derivatization during detection, can be detected together with the above-mentioned compounds to be detected, and the mass spectrometry derivatization and sensitivity detection of multi-residues of cross-class veterinary drugs are realized.

The present invention relates to a transdermal composition comprising a compound selected from the group comprising formoterol, salbutamol, salmeterol, fenoterol, mixtures thereof or salts thereof, and dimethylsulfoxide. The present invention further relates to a composition comprising a compound selected from the group comprising salbutamol, clenbuterol or salts thereof, and comprising at least one of water or a monohydric alcohol.