272 results about "Medicinal plants" patented technology

The invention relates to application of a medicinal plant synergistic repair technology in functional cosmetics. The functional cosmetics comprise the following components in percentage by mass: 0.05-3 parts of peony root bark extract; 0.01 to 3 parts of magnolia flower extract; 0.005 to 0.5 part of a radix scutellariae extract; 0.005 to 0.5 part of a centella asiatica extract; the synergistic component is 0.001-2 parts of radix ophiopogonis root extract, and the preferable mass ratio of the peony root bark extract to the magnolia flower extract to the scutellaria baicalensis extract to the centella asiatica extract is (6-10): (2-4): 1: (1-8). All plant components are natural extracts, do not contain harmful chemical components and are suitable for various skin types, especially sensitive skin, and the soothing and repairing effects are greatly improved through the matching design and synergistic effect of the plant extracts. For example, due to the synergistic effect of the peony root bark extract and the radix scutellariae extract in the anti-inflammatory and antibacterial aspects, the relieving effect on external stimulation is enhanced; the permeability of the compound is enhanced by the radix ophiopogonis root extract, so that the effect is more long-acting.

The invention discloses application of uncaria acidic polysaccharide URP-2 in preparation of an anti-esophageal cancer drug, and belongs to the technical field of antitumor of medicinal plant polysaccharide. According to the method, a method for extracting the uncaria total polysaccharide by boiling water and precipitating the uncaria total polysaccharide by ethanol is adopted, and a DEAE DE-52 cellulose column and sephadex column purification technology is combined, so that the separation of the uncaria acidic polysaccharide component is realized, and the uncaria acidic polysaccharide URP-2 is obtained. The uncaria acidic polysaccharide URP-2 comprises the following components in mole percent: 14.11% of arabinose, 12.64% of rhamnose, 6.48% of galactose, 5.00% of glucose and 61.77% of galacturonic acid. Experiments show that the uncaria acidic polysaccharide URP-2 has remarkable anti-esophageal cancer activity, so that a potential experimental basis and a new strategy are provided for applying the uncaria acidic polysaccharide URP-2 to clinical treatment of esophageal cancer.

The invention discloses an SmCLE mature peptide and application thereof in plant stress resistance, and belongs to the technical field of plant biology. According to the technical scheme, the SmCLE mature peptide is provided, and the amino acid sequence of the SmCLE mature peptide is SEQ ID NO: 1. The CLE peptide is applied to the aspect of plant stress resistance, the problem that an existing CLE peptide cannot be applied to stress resistance of plants, especially medicinal plants or non-mode crops is solved, the CLE peptide has high biocompatibility and targeting performance, and the biomass and yield of the crops in a stress environment can be remarkably improved.

The invention discloses a method for establishing a medicinal plant litsea cubeba tissue culture seedling system. Aiming at the problems of difficulty in explant pollution and browning control, low proliferation and rooting efficiency, insufficient transplanting and domesticating survival rate and the like in establishment of a litsea cubeba tissue culture system in the prior art, the invention provides the establishment method of the medicinal plant litsea cubeba tissue culture seedling system, the germination rate of explants is 90% or above, and the transplanting survival rate in 30 days reaches 90.6%.

The invention discloses application of SmCLE mature peptide in inhibiting plant aging, and belongs to the technical field of plant biology. The invention discloses application of a SmCLE mature peptide in inhibiting plant aging. The amino acid sequence of the SmCLE mature peptide is SEQ ID NO: 1. The CLE peptide is applied to the aspect of inhibiting plant aging, solves the problem that the existing CLE peptide cannot be applied to anti-aging of plants, especially medicinal plants or non-mode crops, has the advantages of small molecular weight, easiness in synthesis, low action concentration and good biocompatibility, can realize accurate regulation and control of leaf aging through exogenous application, and has a wide application prospect. And the safety problem of transgenic organisms is avoided.

The invention relates to the technical field of plant stress regulation and medicinal plant cultivation. A salt stress damage repair method for cutting seedlings of aromatic medicinal plants comprises the following steps: after asexual cutting seedlings of the aromatic medicinal plants suffer from salt stress, spraying a melatonin aqueous solution with the concentration of 50-200 [mu] mol.L to the leaves of the seedlings in a repair window period of 3-6 days after the salt stress occurs, spraying 1-2 times a day, continuously spraying for 2-3 days, and continuously spraying the melatonin aqueous solution with the concentration of 50-200 [mu] mol.L to the leaves of the seedlings in the repair window period of 3-6 days after the salt stress occurs. Melatonin is used for repairing salt damage of the asexual cuttage seedlings of the aromatic medicinal plants. The melatonin can be accurately applied before the salt damage critical point to repair the physiological damage of the cutting seedlings of the aromatic medicinal plants, and the salt damage influence of the cutting seedlings of the aromatic medicinal plants is greatly reduced; the problems that cutting seedlings of the aromatic medicinal plants are prone to salt damage under salt stress, the survival rate is low, and the content of main medicinal components is reduced are solved, and the dual effects of seedling physiological restoration and medicinal component content stabilization can be achieved.

The invention relates to a method for extracting genome DNA of plants rich in secondary metabolites and a buffer solution, and belongs to the technical field of molecular biology and botany. The method solves the technical problems of low DNA extraction efficiency, poor purity, easy degradation and the like when a traditional DNA extraction method is used for treating plant tissues rich in secondary metabolites such as alkaloid, polyphenol and the like. Comprising the following steps: adding a complexing agent such as polyethylene glycol or polyvinylpyrrolidone when grinding plant tissues in a liquid nitrogen environment; splitting by using a cell wall splitting buffer solution containing dithiothreitol and a nonionic surfactant; carrying out DNA release and extraction at 60-70 DEG C by adopting a CTAB (Cetyltrimethyl Ammonium Bromide) extraction buffer solution containing polyethylene glycol and papain; and then purifying and precipitating to obtain high-purity genome DNA (Deoxyribose Nucleic Acid). The method can effectively remove alkaloid, protein and other impurities, significantly improves the DNA yield and purity, and is suitable for genome sequencing, genetic resource protection, medicinal plant molecular identification and the like of plants with high secondary metabolites such as Stephania kwangsiensis and the like.

The invention discloses application of a tripterygium wilfordii exosome in preparation of an anti-cervical cancer medicine and a tumor angiogenesis inhibiting medicine, and relates to the field of biological medicine. The medicinal plant exosome derived from tripterygium wilfordii is successfully separated, and it is proved that the medicinal plant exosome can regulate related pathways through delivery of functional nucleic acid molecules to inhibit proliferation and migration of cervical cancer cells and promote active oxygen related apoptosis so as to be used for tumor treatment. The tripterygium wilfordii exosome can further act on vascular endothelial cells in a tumor microenvironment, the migration function of Hela cells is inhibited, and then the effect of resisting cell proliferation in the tumor microenvironment is achieved. The tripterygium wilfordii exosome has the advantages of being simple in preparation method, remarkable in tumor growth resistance and tumor cell migration inhibition effect, good in biocompatibility, high in delivery efficiency and the like, and can be used as a novel nano-drug for tumor treatment.

The invention belongs to the technical field of medicinal plant tissue culture, and particularly discloses a culture medium for inhibiting browning of fructus amomi explants, the pH value of the culture medium is 5.0-6.0, the culture medium contains KNO3, NH4NO3, KH2PO4, MgSO4. 7H2O, CaCl2. 2H2O, MnSO4. 4H2O, ZnSO4. 7H2O, H3BO3, VB1, VB6, VB5, soybean mash filtrate, salicylic acid and the like, the formula of the culture medium aims at solving the problem of tissue culture browning of fructus amomi, and extremely low ammonium, organic nitrogen synergism and microelement regulation are adopted. By adopting the culture medium, the browning rate in the villous amomum fruit tissue culture process can be effectively inhibited, the seedling quality and the production efficiency are remarkably improved, the seedling culture period and the seedling culture cost can be greatly reduced in the villous amomum fruit seedling rapid propagation culture process, and a technical guarantee is provided for commercial seedling supply.

The invention discloses a seedling breeding and under-forest cultivation method for Schefflera octophylla. Relates to the technical field of medicinal plant cultivation. Comprising the following steps: seed treatment; sowing and germinating; seedling cultivation; performing under-forest field planting; and managing after planting. The germination rate is high and neat; seedlings are robust and strong in stress resistance; the field planting survival rate is obviously improved, and the under-forest field planting survival rate is stabilized to be 85% or above; the whole technical route does not need to use chemical pesticides and chemical fertilizers, the Yunnan pine forest land resources are utilized, bionic cultivation of the stichopus japonicus is achieved, the ecological environment is protected, and technical support is provided for production of high-quality medicinal materials of the stichopus japonicus.

The invention belongs to the technical field of medicinal plant tissue culture, and particularly discloses a culture medium for inhibiting browning of paris polyphylla explants, and the culture medium is prepared from the following components: 450 to 1300 mg / L of KNO3, 350 to 1220 mg / L of NH4NO3, 50 to 240 mg / L of KH2PO4, 135 to 560 mg / L of MgSO4. 7H2O, 220 to 920 mg / L of CaCl2. 2H2O, 15.2 to 30.5 mg / L of MnSO4. 4H2O, 500 to 5000 mg / L of sodium bentonite and the like. The phyllosilicate structure is utilized to efficiently adsorb phenolic substances, and the enzymatic browning chain reaction is blocked; meanwhile, high calcium salt concentration is maintained to enhance the stability of cell membranes and inhibit exosmosis of phenolic substances. By adopting the culture medium disclosed by the invention, browning can be effectively inhibited, the seedling quality and the production efficiency can be remarkably improved, the seedling culture period and the seedling culture cost can be greatly reduced in the rapid propagation culture process of the paris polyphylla seedlings, and a technical guarantee is provided for commercial seedling supply.

The abstract relates to the field of pharmacy, in particular, to a method for obtaining extracts from medicinal plants and can be used for the production of biologically active additives, cosmetics and medicines with antioxidant, rejuvenating and anti-inflammatory effects. The essence of the utility model is the development of a technology for obtaining a liquid extract rich in biologically active compounds by ultrasonic processing of Rosa platyacantha Schrenk leaf raw materials. The method includes the following steps: 1. Preparation of plant raw materials (grinding to 5 mm); 2. Preparation of extractant (50% ethyl alcohol); 3. Extraction of raw materials and extractant in a ratio of 1:10 (Elma Elmasonic Easy 30H); 4. Filtration of the resulting liquid extract; 5. Packaging and labeling of the finished product. Extraction is carried out at a temperature of 35°C and a frequency of 37 kHz for 30 minutes. The technical result of the proposed approach is the development of a resource-saving technology for obtaining a liquid extract from the leaves of Rosa platyacantha Schrenk, ensuring a reduction in extraction time, a low temperature regime while preserving thermolabile biologically active substances, and an expansion of the raw material base through the use of previously unused parts of the plant.

This invention discloses a *Armillaria mellea* contact induction device and control system for improving the inoculation rate after *Gastrodia elata* seed germination. It relates to the field of co-cultivation technology of edible and medicinal fungi and medicinal plants, and includes a shell, a germination support module, a mycelial induction module, a contact bridge module, a nutrient pulse module, an environmental modulation module, a dual-evidence detection module, and a main control module. The main control module generates an inoculation window index and, after trial contact, switches between a maintained contact state and a withdrawal state based on the recovery curve to complete the contact induction and colonization maintenance of *Armillaria mellea* with *Gastrodia elata* protocorms.

The application discloses a SNP site and KASP marker combination related to contents and proportions of ginsenosides Rg1 and Rb1 in Panax notoginseng and application thereof, and belongs to the technical field of medicinal plant molecular breeding and quality evaluation. In view of the problems of lack of molecular markers synchronously related to contents and proportions of ginsenosides Rg1 and Rb1 in Panax notoginseng and long breeding cycle in the prior art, nine SNP site combinations located on a Chr11 chromosome of Panax notoginseng genome are screened, and a KASP marker combination and primer combination are developed based on four sites of SNP3-SNP6 among them. The KASP marker combination has strong specificity, is convenient to detect, has high throughput, is low in cost, and can accurately identify the contents and proportions of Rg1 and Rb1 in Panax notoginseng samples. The application can be used for Panax notoginseng germplasm resource screening and molecular marker assisted breeding, early identification of target traits is realized, the breeding cycle is shortened, the breeding efficiency is improved, and technical support is provided for directional cultivation of Panax notoginseng high-quality varieties.

This invention discloses a low-temperature enzymatic hydrolysis compound beverage made from edible and medicinal plants, and its preparation method. Using jujube powder as a base, at least two kinds of dried powders from medicinal and edible plants are compounded. Enzymatic hydrolysis is performed using a compound enzyme containing cellulase, pectinase, and acidic protease at 45-50℃ and pH 4.0-5.0. The product is then subjected to enzyme inactivation and solid-liquid separation (filtration / centrifugation or a combination thereof). Amylase can be added for high-starch / polysaccharide raw materials. The product contains no added flavorings, colorings, sweeteners, or preservatives. After 12 months of storage at room temperature, the sedimentation rate is ≤0.5%, and the retention rate of active ingredients is 26%-31% higher than that of traditional high-temperature processes. The process is highly versatile and can be adapted to different separation methods, enabling the industrial production of clean-label, highly stable plant-based beverages.

The invention relates to the technical field of medicinal plant seedling culture, in particular to an industrialized seedling culture method for shortening the growth period of scutellaria baicalensis, which adopts a multi-layer seedling culture rack integrated sensor network, a tidal irrigation system, a vermiculite and perlite matrix recycling technology and a digital management platform to reduce the matrix cost and improve the space utilization rate. Cultivation environment parameters and water and fertilizer supply are dynamically regulated and controlled, and three-dimensional, precise and efficient scutellaria baicalensis seedling culture is achieved. According to the method, the scutellaria baicalensis seedling raising period is remarkably shortened to 1 / 2 of that of a traditional method, the seedling survival rate is increased to 85% or above, common diseases and pests in traditional seedling raising are reduced, meanwhile, 80% of planting space is saved, and the method is suitable for large-scale production.

This invention discloses the application of Uncaria rhynchophylla neutral polysaccharide URP-W in the preparation of anti-glioma drugs, belonging to the field of anti-tumor technology of medicinal plant polysaccharides. The invention obtains a crude polysaccharide extract from Uncaria rhynchophylla through hot water extraction and ethanol precipitation, followed by purification using a DEAE cellulose column and G200 dextran gel to obtain Uncaria rhynchophylla neutral polysaccharide URP-W. The monosaccharide composition of URP-W includes arabinose, rhamnose, galactose, glucose, xylose, mannose, galacturonic acid, and mannuronic acid in a molar ratio of 17.99:6.32:21.71:27.17:2.56:7.57:16.20:0.49. Experiments have shown that URP-W can inhibit the proliferation of gliomas and induce apoptosis, exhibiting significant anti-tumor activity against glioma cells, providing a new drug raw material and treatment method for the clinical treatment of gliomas.

The invention relates to the technical field of genome assembly, in particular to a medicinal plant genome assembly method and system based on high-throughput sequencing. The method comprises the following steps: acquiring a target sequencing sequence, and screening a function influence sequence; performing repetitive classification on the target sequencing sequence to obtain a non-repetitive sequence cluster and a repetitive sequence cluster, and dividing the repetitive sequence cluster into a functional repetitive sequence and a non-functional repetitive sequence; determining dynamic association strength by combining expression abundance of functional genes, content detection of medicinal components and base overlapping characteristics of adjacent sequences; constructing an association network; and according to the dynamic association strength in the association network, aiming at the functional association type repetitive sequence, the non-functional association type repetitive sequence and the adjacent non-repetitive sequence, respectively carrying out sequence splicing by adopting a differential assembly path to obtain a complete genome assembly result. According to the method, the problems of splicing errors, fragment breakage and redundancy caused by repeated sequences can be solved, and the assembly accuracy and integrity are remarkably improved.

The invention discloses a medicine lotus cell suspension factory system and method for directionally producing high-activity components based on a healthy target spot, and the system is characterized in that a health-oriented cell line design module, an intelligent scale culture module, a precise metabolism induction module and a targeted separation and product development module are in closed-loop linkage; and an innovative mode of reversely designing a production process from health requirements is realized. According to the method, aiming at specific targets of epidemic resistance, depression resistance, reproductive health and the like, a high-yield cell line is created through multi-omics analysis screening or gene editing, and large-scale culture is performed in an optimally controlled bioreactor; and the elicitor is utilized to accurately stimulate a metabolic pathway to directionally enrich high-value components such as liensinine, nuciferine, epigallocatechin gallate and the like. And finally, preparing a standardized extract by adopting a green extraction technology (such as ultrasonic extraction and supercritical CO2 extraction), wherein the standardized extract is used for functional foods, dietary supplements or medical products.

The invention belongs to the technical field of medicinal plant cultivation, and particularly provides a method for increasing the content of sesquiterpene glycoside in dendrobium nobile. The method comprises the step of applying a magnesium ion-containing solution with effective concentration at the growth stage of dendrobium nobile. Preferably, the magnesium ion-containing solution is a magnesium chloride solution, the application concentration is 10-500 mg / L, the magnesium ion-containing solution is applied in a foliage spraying or root irrigation mode, and the key period of application is the rapid growth period or the effective component accumulation period of the dendrobium nobile. The promotion effect of exogenous magnesium ions on biosynthesis of the sesquiterpene glycoside of the dendrobium nobile is disclosed for the first time, and the content of sesquiterpene glycoside components in the dendrobium nobile medicinal material can be remarkably increased under the condition that a basic cultivation mode is not changed, so that the medicinal potential and market value of immunoregulation, anti-inflammation and the like of the dendrobium nobile medicinal material are enhanced. The method is simple, efficient, low in cost, free of pollution and suitable for industrial application.

The application provides a preparation method of medicinal plant atomized particles. The preparation method of the medicinal plant atomized particles comprises the following steps: selecting a medicinal part of a medicinal plant for decocting operation, separating a plant liquid and residues after decocting; distilling the plant liquid to obtain medicinal volatile oil and an aqueous solution; distilling and concentrating the aqueous solution to obtain a concentrated aqueous solution; drying the residues, and then grinding the dried residues to obtain medicinal residue powder; mixing the medicinal volatile oil, the concentrated aqueous solution and the medicinal residue powder according to a preset proportion, and performing granulation operation to obtain to-be-atomized particles; and placing the to-be-atomized particles into an atomization device for atomization administration. The preparation method of the medicinal plant atomized particles has the effects of less dosage, faster effect and more convenient use.

The invention provides a planting method for regeneration, renewal and rejuvenation of branches of daphniphyllum calycinum, and relates to the field of medicinal plant planting. The invention discloses a planting method for regenerating, renewing and rejuvenating branches of daphniphyllum calycinum. The planting method comprises the following steps: (1) selecting daphniphyllum calycinum plants which are planted for more than 2 years; (2) branch cutting treatment is carried out in winter; (3) taking a leaf arbuscular branch of the tree body as a pruning branch, and pruning from the base part of the leaf arbuscular branch 5-10 cm away from a branching point; (4) treating crops for rotation of the cut tree body by using a plant healing agent; and (5) forming new leaf arbuscular branches from the new shoots. Through special branch cutting treatment, a shrub shape is formed, the yield proportion of daphniphyllum calycinum is effectively increased, the quality is guaranteed, and the production benefit is remarkably increased. The branch cutting regeneration is a relatively effective method for harvesting the daphniphyllum calycinum, so that not only can the purposes of alternation and renewal of the daphniphyllum calycinum tree body be realized, but also stable yield and high quality are ensured, the decline of stumping treatment and yield loss are made up, a benign growth and harvesting cycle can be formed, and the effect is obviously superior to that of a traditional method.

The utility model relates to medicinal plant screening technical field, concretely is a kind of medicinal plant screening processing device, including base, the base is openwork, connect device with factory power supply, when equipment starts, operating personnel opens motor through control switch, motor is market product, the rotating shaft of motor output end drives gear rotation, gear is engaged with the disc tooth on mandrel, make mandrel rotate, and then drive the synchronous rotation of eccentric wheel of both ends, in the rotation process of eccentric wheel, the fixed plate of one side of screen frame is periodically pushed and pulled by push-pull link, make screen frame reciprocating vibration along the roller track in cross bar sliding groove, after screening material pours from screen frame, under the action of screen vibration, medicinal plant slides along the inclined screen and falls to discharge port and is discharged, fine impurity particle that meets screen mesh aperture passes through screen, under the action of screen vibration and inclination angle, continue to move to screen low end, finally discharge outlet two of bottom plate are discharged, realize the efficient screening and classification of material.

The invention belongs to the field of plant biotechnology and medicinal plant cultivation, and relates to application of melatonin in artemisinin biosynthesis and a method for increasing the content of artemisinin in artemisia apiacea. The melatonin is applied to the artemisia apiacea plants, the content of artemisinin in the artemisia apiacea is increased, and compared with an existing method, the method is more economical and efficient.

The utility model relates to the technical field of medicinal plant raw material extraction, especially relates to a low-temperature press of sea buckthorn seed oil. A low-temperature press of sea buckthorn seed oil has a support, a press cylinder, a first servo motor, a spiral oil press roller, an oil storage tank and an arc-shaped heat dissipation fin group, the press cylinder is installed at the top of the support, the right side of the press cylinder is provided with the first servo motor, the output shaft of the first servo motor is fixedly connected with the spiral oil press roller, the space inside the press cylinder and the spiral oil press roller gradually decreases from right to left, the lower part of the press cylinder is fixedly connected with the oil storage tank, and the upper part of the press cylinder is fixedly connected with the arc-shaped heat dissipation fin group in a symmetrical manner around the periphery. The utility model adopts the design that the spiral oil press roller and the internal space of the press cylinder gradually decrease, and is combined with the arc-shaped heat dissipation fin group, so that the oil extraction rate is improved, the effective heat dissipation system is matched to maintain a low-temperature operation environment, the nutritional ingredients in the sea buckthorn seed oil are maximally reserved, and the quality of the product is improved.

The invention discloses application of cynarin in preparation of a medicine for resisting respiratory syncytial virus. The cynarin is polyphenolic acid cynarin, and the respiratory syncytial virus is an RSV-A2 strain; the compound can effectively inhibit replication of respiratory syncytial viruses, is a monomer component of natural medicinal plants, is clear in structure, stable in chemical property, easy in quality control and free of obvious toxic and side effects, can effectively resist inflammation while serving as an active component of a natural small-molecule antiviral drug, and has a broad application prospect. Viral lung inflammatory infiltration and lung injury caused by the respiratory syncytial virus are relieved.

The application provides an enhanced hyperspectral framework method for storing medicinal plant pest classification, comprising: the framework collects near-infrared hyperspectral images of medicinal plant samples, and constructs a dataset containing healthy level, mild infestation level and severe infestation level through controlled artificial infestation to obtain real spectral data as a basis; the framework adopts a Wasserstein generative adversarial network model with gradient penalty to enhance the real spectral data, generate synthetic spectral data to balance the class distribution and increase the sample diversity, wherein the model ensures the fidelity of the generated data through adversarial training; and the framework applies a convolutional neural network classifier, a support vector machine classifier and a random forest classifier based on the enhanced dataset for pest classification, wherein the convolutional neural network classifier achieves the best performance and realizes the accuracy improvement.

The invention discloses a cultivation method of dendrobium officinale parasitizing on taxus chinensis stumps, and relates to the technical field of parasitic cultivation and bonsai modeling of medicinal plants and rare short trees. According to the method, short taxus chinensis trees are subjected to material selection, disinfection curing and water retention modification pretreatment, dendrobium officinale seedlings are subjected to seedling selection, seedling hardening and domestication and root promotion treatment, then a parasitic planting system is constructed by adopting a moss buffer layer in combination with a flexible fixing mode, and through cooperation with precise parasitic environment regulation and control and a scientific maintenance management system, the survival rate of the dendrobium officinale seedlings is increased. The stable parasitism of the dendrobium officinale and the taxus chinensis brachycarpus is realized. According to the method, the disease rate of the dendrobium officinale is effectively reduced, the medicinal component content of the dendrobium officinale is increased, meanwhile, the high-ornamental-value bonsai is formed by fusing the short wood and the dendrobium, resource recycling is achieved, remarkable ecological, economic and ornamental values are achieved, and industrialization replication can be promoted.

Phthalide lactones, as an important class of benzopentolactone skeleton, are widely distributed in natural products, medicinal plants and bioactive molecules, and have significant pharmacological activities and synthetic application potential. This kind of structure not only shows various biological activities such as antibacterial, anti-inflammatory, antitumor, antioxidant, but also is an indispensable core structural unit in many drug molecules and lead compounds. At the same time, cyano is a very valuable functional group in the field of organic synthesis and medicinal chemistry, with strong electron-withdrawing properties, strong structural stability and other advantages, which can effectively improve the electronic distribution, lipid solubility and drug performance of the molecule. In view of the important significance of phthalide lactones and cyano in organic synthesis and drug research and development, the present invention develops a synthetic method for efficiently constructing cyano-containing alkyl chain substituted phthalide lactone compounds. It has important value in medicinal chemistry and organic synthesis.

The invention relates to the technical field of medicinal botanical bactericides, in particular to application of kushenol F in preparation of antibacterial drugs. The sophora alcohol F is found to be used for inhibiting the growth of phytophthora nicotianae and alternaria tenuissima. Compared with the traditional chemically synthesized antibacterial agent, the compound has lower toxicity and lower potential risk to the environment and human health, and provides a new choice for disease control in agricultural production.