14 results about "Growth cycle" patented technology

The invention discloses lachnum brevipilosum and application of the lachnum brevipilosum, and belongs to the technical field of fungal biology. The strain is separated from Vaccinium dunalianum twigs, can be used as a microbial source of a natural wood flavoring material, and particularly, it is found that the strain can produce (-)-isohorn ene in microbial metabolites for the first time, so that the blank of synthesis research of microbial wood flavoring components is filled up; the application method comprises the steps of strain activation, solid fermentation culture, dynamic collection of headspace volatile matters and the like, and a fermentation product is composite fragrance containing alcohols, olefins and other components and has rich-layered wood-soil fragrance-spicy composite fragrance; the natural wood perfume is produced in a microbial fermentation mode, the problems that plant raw materials are long in growth cycle and unstable in supply can be solved, and the method has the advantages of being controllable in process, not limited by seasons and regions and high in sustainability.

The invention provides an anti-hair loss and hair growth composition based on cyclic polypeptide c8DSS as well as a preparation method and application of the anti-hair loss and hair growth composition, and relates to the technical field of anti-hair loss and hair growth compositions. The hair loss preventing and hair growing composition based on the cyclic polypeptide c8DSS is prepared from the following components in percentage by mass: 0.45 percent to 1.36 percent of the cyclic polypeptide c8DSS, 0.45 percent of a stable protective agent, 2.73 percent of a penetration enhancer, 2.912 percent of a moisturizing stabilizer and the balance of purified water. The straight-chain 8DSS polypeptide is cyclized into c8DSS, so that the stability and the biological activity of the c8DSS polypeptide are remarkably improved; meanwhile, the annular structure keeps the optimal spatial configuration, the binding capacity with a cell receptor is enhanced, the hair follicle growth cycle can be regulated and controlled through hair follicle sebaceous gland deep penetration, and hair follicles are promoted to enter a growth period from a resting period in advance. The traditional Chinese medicine composition is scientific and reasonable in formula, can be prepared into various dosage forms, is convenient to use, good in safety, free of obvious side effects and wide in application range, and has good market application prospects.

The invention relates to stem cell-derived engineered nano-vesicles (e-NVs) for promoting hair growth, the engineered nano-vesicles are prepared from stem cells through engineering induction, apoptosis induction and programmed serial extrusion processes in sequence, and an inducer used for engineering induction is 3, 3 '-diindolylmethane. The particle size of the engineered nano vesicle is mainly distributed in a range of 50-300 nm, the polydispersity coefficient is 0.05-0.20, and the expression proportion of phosphatidylserine is 40%-50%. The rice vesicles can effectively improve the hair follicle microenvironment, adjust the hair growth cycle, promote proliferation and differentiation of hair follicle stem cells and remarkably increase the hair regeneration rate of androgenetic alopecia model mice, and a safe, convenient and efficient clinical strategy is provided for hair regeneration treatment.

The invention relates to the technical field of organic fertilizers, in particular to a vegetable organic fertilizer and a preparation method thereof. The vegetable organic fertilizer comprises the following raw materials in parts by weight: 60-80 parts of sludge, 10-20 parts of a base material, 4-6 parts of a fiber material, 4-6 parts of a powder material, 2-4 parts of brown sugar and 0.01-0.03 part of a fermentation inoculant. In the fiber material, fiber components contained in animal hair and bamboo are utilized, active silicon released by bamboo fibers is combined with humic acid to form a net structure, potassium ions are wrapped to realize staged release, and keratinase can decompose insoluble keratin in the animal hair into oligopeptide, so that bacillus licheniformis is further mineralized into ammonium nitrogen, and the content of the potassium ions in the animal hair is reduced. The release period of the organic fertilizer is synchronous with the growth period of the vegetables, so that the organic fertilizer can continuously release fertility in the growth period of the vegetables, the vegetables can receive nutrition supply brought by the organic fertilizer in all growth stages, and the purpose of improving the growth efficiency of the vegetables is achieved.

The invention provides a traditional Chinese medicine composition for treating alopecia, a traditional Chinese medicine preparation and application thereof. The traditional Chinese medicine composition comprises the following traditional Chinese medicine raw materials in parts by weight: 1-50 parts of radix polygoni multiflori preparata, 1-50 parts of fructus ligustri lucidi, 1-50 parts of herba ecliptae, 1-50 parts of rhizoma polygonati, 1-50 parts of mulberries, 1-50 parts of radix angelicae sinensis, 5-100 parts of radix salviae miltiorrhizae, 1-50 parts of rhizoma chuanxiong and 1-50 parts of flos carthami. The traditional Chinese medicine composition can inhibit apoptosis, prolong the hair growth cycle and promote hair growth.

This invention relates to the field of biotechnology, and more particularly to the application of the chi-miR-1388-3p gene in the melatonin-mediated regulation of cashmere growth in cashmere goats. This invention discovers a microRNA (chi-miR-1388-3p) associated with the growth cycle of cashmere goat hair follicles, which can regulate the proliferation, cell cycle, or apoptosis of hair papilla cells in cashmere goat skin, thereby regulating cashmere goat hair follicle growth and cashmere growth. Furthermore, this invention is the first to discover that melatonin-mediated interference with chi-miR-1388-3p promotes the proliferation of hair papilla cells in cashmere goat skin, regulates the cell cycle, and inhibits apoptosis, providing valuable insights into the regulatory role of melatonin-mediated miRNAs in cashmere goat hair follicle growth.

The invention discloses anti-hair loss and hair growth liquid containing collagen carbon quantum dots and a preparation method of the anti-hair loss and hair growth liquid. The anti-hair loss and hair growth liquid is prepared from the following raw materials in percentage by weight: 0.0001 to 0.1 percent of collagen carbon quantum dots, 1 to 40 percent of nutrition repairing agent, 0.1 to 10 percent of penetration enhancer, 0.01 to 2 percent of protective agent, a proper amount of pH (Potential of Hydrogen) regulator and the balance of purified water. Through the biological activity of the collagen carbon quantum dots and the synergistic effect of multiple components, hair follicle cell proliferation and differentiation are promoted, and the damaged hair follicle tissue structure is repaired; hair follicles are stimulated to be converted from a rest period to a growth period, and the hair growth period is prolonged; the composition can improve the scalp microenvironment, enhance the absorption of nutrient substances and reduce the inflammatory response around hair follicles, so that the alopecia problem is improved, the effects of densifying and blackening hair are achieved, and the composition has wide application prospects and is beneficial to popularization and application.

The invention discloses an extracting solution capable of growing hair and an extracting method thereof, and belongs to the field of hair growing preparations. The extracting solution comprises saw palmetto fruit extract, ginseng root extract, caffeine, a modified cationic liposome compound, modified metal-polyphenol network nanoparticles and a buffer solution. Wherein the modified cationic liposome compound is obtained by forming a lipid membrane from specific phospholipids and cationic lipids, hydrating, ultrasonically preparing a liposome suspension, adding polylysine and targeting peptide, incubating, and performing sucrose density gradient centrifugal purification. The extraction method comprises the following steps: mixing and stirring the components, fixing the volume by using a buffer solution, filtering and sterilizing. According to the extracting solution, modified compounds cooperate with natural components, active substances are delivered to a hair follicle microenvironment in a targeted mode, hair follicle stem cell proliferation related pathways are activated, hair follicle degeneration factors are inhibited, the growth cycle of hair follicles is regulated and controlled from multiple targets, hair growth is effectively promoted, and the obvious hair growing effect is achieved.

The invention discloses a ganoderma lucidum drug effect cultivation system and method based on an artificial intelligence health system, and relates to the technical field of ganoderma lucidum directional drug effect cultivation, and the system comprises a central processor which is used for coordinating the operation of all modules in the use process of a scheduling system and processing global data; and the four-diagnosis data acquisition module is used for acquiring tongue diagnosis, face diagnosis, eye diagnosis and hair diagnosis feature data of the user to obtain multi-dimensional physiological feature data. Through cooperative use of the health analysis module and the ganoderma lucidum cultivation formula generation module, the physical characteristics and health requirements of a user can be accurately identified, the optimal matching of traditional Chinese medicine ganoderma lucidum and healthy food is generated, and a ganoderma lucidum cultivation formula completely matched with the individual condition is generated; and toxic substances are decomposed or converted through a microbial metabolic pathway while effective components of traditional Chinese medicines are enriched, so that the ganoderma lucidum is a new variety with certain properties of the traditional Chinese medicines, and the ganoderma lucidum is short in growth cycle and high in yield.

The invention relates to a multi-effect synergistic hair loss preventing and hair growth promoting composition and a preparation method thereof, and belongs to the technical field of daily chemicals, the hair loss preventing and hair growth promoting composition comprises a hair loss preventing and hair growth promoting component composed of hydrolyzed collagen, myristoyl pentapeptide-4, sphingosine dihydro (neurosphingosine) and pyrrolidinyl diaminopyrimidine oxide, the plant extracting solution is prepared from viburnum przewalskii, South America milk vine bark, saw palmetto fruit and trifolium pretense. According to the hair loss preventing and hair growing component, different components are combined to construct a multi-channel hair loss preventing and hair growing system capable of effectively prolonging the growth period of hair follicles, strengthening the structure of the hair follicles, enhancing the vitality of the hair follicles and balancing the growth cycle of the hair, so that the prepared composition finished product has outstanding hair loss preventing and hair growing effects; besides, the plant extracting solution prepared from the selected plant raw materials can also form all-around guarantee on the scalp barrier, so that the composition finished product can have the effect of repairing the scalp barrier by adding the plant extracting solution into the composition.

The present application relates to a kind of engineered stem cell nanometer apoptotic bodies, its preparation method includes the following steps: by 3,3'-diindolylmethane directional induction obtains the engineered stem cell rich in repair and anti-inflammatory signal molecules, and then the engineered stem cell is induced to apoptosis, and the supernatant is separated and obtained by collection, then the programmed tandem extrusion process is handled to the engineered apoptotic body, and the particle size uniformity of the engineered nanometer apoptotic body is prepared.The engineered nanometer apoptotic body of the present application can effectively improve the microenvironment around hair follicle and regulate hair growth cycle, significantly improve the hair density and regeneration rate of androgenetic alopecia model mice, provide a new strategy of safe, convenient and efficient for clinical hair regeneration treatment.

The invention discloses an application of apigenin in preparation of a product for preventing and treating alopecia, and relates to the technical field of alopecia prevention and treatment, and the key point of the technical scheme is that the apigenin can play a role in regulating the hair follicle cycle in the hair follicle growth and development process, specifically, the apigenin activates hair follicle stem cell proliferation, promotes the hair follicle to change from a resting stage to a growing stage, and promotes the hair follicle growth. The apigenin can promote hair growth, can theoretically treat alopecia diseases such as androgenetic alopecia, alopecia areata and alopecia in a growing period caused by human hair growth cycle stagnation, and has the advantages of wide source of apigenin, low cost and high biological safety.

The present invention belongs to the field of medicine and cosmetics technology and discloses a biotin tripeptide with hair growth properties, a preparation method, a composition thereof, and its application. The biotin tripeptide is selected from biotin YHK, biotin DHK, and biotin RHK, or pharmaceutically or cosmetically acceptable salts and acylated products thereof; the composition is a combination of two of the aforementioned tripeptides; or a combination of three; or a combination of two or three combined with the addition of other hair growth polypeptides commonly found in cosmetics. The novel biotin tripeptide and its composition of the present invention have excellent hair growth properties, can promote hair growth and increase hair thickness, regulate the growth cycle of hair follicles, increase hair growth rate, and increase hair volume. The biotin tripeptide and its composition of the present invention can be used in medicine and / or cosmetics. Therefore, this type of compound has good application prospects.