650 results about "Hair loss" patented technology

The compositions and methods provided herein include a pharmaceutical formulation for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Also provided herein are pharmaceutical formulations for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof and one or more additional active agents. Also provided herein are methods of treating hair loss by administering to a subject in need thereof a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Further provided herein is a kit including a slow modified release vehicle comprising oral minoxidil or a pharmaceutically acceptable salt thereof.

The invention relates to the field of biological medicine, in particular to a hair follicle targeted delivery system and hair growth and hair loss prevention cosmetics, the hair follicle targeted delivery system comprises: a lipid nanoparticle core which is internally loaded with a bioactive component with hair growth and hair loss prevention effects; the hair follicle targeting molecule can specifically recognize and bind to a receptor on the surface of a hair follicle cell; a targeting anchoring conjugate composed of a linker covalently linked to the hair follicle targeting molecule and an anchoring lipid; wherein the targeting anchoring conjugate is embedded into the lipid bilayer of the lipid nanoparticle core through the anchoring lipid, so that the hair follicle targeting molecule is displayed on the surface of the lipid nanoparticle core. According to the application, through an innovative targeted anchoring conjugate structure, the targeting property and enrichment efficiency of hair growth and hair loss prevention active ingredients on hair follicle tissues can be remarkably improved, and the effect that a medicine accurately acts on a focus part is ensured, so that the number of hair follicles at an alopecia areata modeling part can be remarkably increased.

The invention discloses a mint McTTG1 gene as well as an expression protein and application thereof, and belongs to the technical field of plant genetic engineering. The nucleotide sequence of the mint McTTG1 gene disclosed by the invention is shown as SEQ ID NO.1, the amino acid sequence of the expression protein of the mint McTTG1 gene is shown as SEQ ID NO.2, and the mint McTTG1 gene belongs to WD40 family genes participating in regulation and control of epidermal hair development and synthesis of anthocyanin and procyanidine. Transgenic experiments show that after the McTTG1 gene is over-expressed in the arabidopsis thaliana mutant ttg1-13 with epidermal hair loss and significantly reduced accumulation of anthocyanin and procyanidine, the formation of the epidermal hair on the surface of the mutant can be recovered, and the accumulation of anthocyanin and procyanidine can be promoted. Gene resources are provided for plant variety improvement, and cultivation of new mint varieties is facilitated.

The invention discloses a traditional Chinese medicine anti-hair-loss pilatory formula and a preparation method thereof, the traditional Chinese medicine anti-hair-loss pilatory formula comprises a cacumen biotae extract, a polygonum multiflorum extract, a herba ecliptae extract and other components, and a multi-target synergistic effect is realized through specific proportion compatibility. The preparation method comprises the steps of medicinal material pretreatment, staged decoction, concentration, stabilizer addition and the like. The black bean juice steaming technology is adopted to enhance the activity of polygonum multiflorum, the formula is optimized, the stability and the mildness are improved, and the requirements of modern consumers are met. The product has a remarkable anti-hair loss effect, can be applied to the fields of anti-hair loss shampoo, scalp care solution and the like, and has a high-activity component retention rate and a shelf life of 18 months or above.

The present application provides a kind of Radix Polygoni Multiflori active ingredient separation and purification process, belong to plant extraction technical field.The present application separation and purification process includes: Radix Polygoni Multiflori ethanol ultrasonic extraction, activated carbon adsorption, HPD-100 macroporous resin purification, membrane filtration, ultrafiltration, reduced pressure concentration and crystallization step, can efficiently extract Radix Polygoni Multiflori extract with high 5 alpha-reductase inhibitory activity.After compounding with the extract of Euonymus alatus obtained by specific microbial fermentation, the anti-hair loss effect can be significantly enhanced.The in vitro experimental results show that the Radix Polygoni Multiflori extract and the extract of Euonymus alatus both have significant 5 alpha-reductase inhibitory activity.The present application can effectively promote hair growth and improve hair loss, and the effect is close to the positive control drug.The present application process is stable, high in purity, strong in activity, suitable for industrial production, and has good market application prospect.

The invention provides a hair care composition with oil control, hair loss prevention and repair effects and a preparation method of the hair care composition, and belongs to the technical field of hair care. The hair care composition comprises functional peptides such as myristoyl pentapeptide-4, palmitoyl tripeptide-1, acetyl tetrapeptide-3, hexapeptide-3, acetyl hexapeptide-8, palmitoyl tetrapeptide-7 and the like which are synergistically combined according to a specific proportion, and glycerin, water and a penetration enhancer are supplemented to form a basic system. By optimizing peptide structure modification, adding proportion and the steps of pH control, ultrasonic treatment and collaborative assembly in the preparation process, multi-path collaborative regulation and control of hair follicle activation, scalp inflammation inhibition and keratin synthesis enhancement are realized.

The invention relates to traditional Chinese medicine fermentation liquor, in particular to a preparation method and application of the traditional Chinese medicine fermentation liquor. Through the double-bacterium symbiotic fermentation technology, traditional Chinese medicine macromolecules are decomposed into micromolecules through fermentation, efficient absorption of the skin can be promoted, and by combining with the thuja old ointment, the antibacterial rate is increased, the skin barrier repairing function is achieved, and the thuja old ointment can be used for daily chemical products such as handmade soap, hand sanitizer, shower gel, shampoo and facial cleanser. Therefore, a multi-effect synergistic effect of cleaning, fixing hair, preventing hair loss and nourishing skin is realized.

The invention discloses a composition for regulating scalp micro-ecology, which comprises a component A and a component B, the component A is prepared from the following components in parts by weight: 5 to 15 parts of amur corktree bark extract, 3 to 14 parts of rhizoma coptidis root extract, 5 to 15 parts of radix sophorae flavescentis extract, 2 to 8 parts of rhus chinensis insect gall extract, 2 to 18 parts of fructus cnidii extract, 3 to 10 parts of pericarpium zanthoxyli extract, 1 to 5 parts of camphor tree root extract, 3 to 12 parts of ginger root extract, 5 to 15 parts of radix polygoni multiflori extract and 5 to 25 parts of swertia japonica extract; 10-30 parts of a Chinese arborvitae twig and leaf extract; the component B is prepared from the following components in parts by weight: 70 to 90 parts of cocamidopropyl-PG-sodium dimethyl ammonium chloride phosphate, 10 to 30 parts of sodium isostearoyl lactylate and 1 to 10 parts of dichlorobenzyl alcohol; the weight ratio of the component A to the component B is 10: 1. The composition can effectively regulate scalp micro-ecological balance, remarkably inhibit overgrowth and reproduction of common harmful bacteria on scalp, protect or moderately promote growth of beneficial bacteria on scalp, maintain healthy flora structure and diversity, fundamentally improve scalp health by recovering and maintaining the balance state of scalp micro-ecology, and improve scalp quality. The shampoo has multiple good effects of controlling oil, preventing alopecia, relieving itching and removing dandruff.

1. Name of the product in this design: Hair growth cap. 2. Purpose of this design: This design is intended for treating hair loss and promoting hair growth. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: 3D view 1.

The invention relates to the technical field of hair care, and discloses a portable hair care cap based on a phototherapy module, the portable hair care cap comprises a cap body, the phototherapy module is fixedly mounted in the cap body, the outer wall of the cap body is fixedly connected with a shell, and an intelligent control module and a power supply device are arranged in the shell; the intelligent control module is electrically connected with the phototherapy module and the power supply device, and the helmet further comprises a heat dissipation mechanism and a buffer mechanism which are integrally arranged between the phototherapy module and the helmet body; a dynamic power adjusting module and a multi-area cooperative control module are arranged in the intelligent control module. The scalp is divided into independent control areas such as the head top, the foreangle and the temple, each area is provided with an independent LED array and a driving circuit, a user is supported to customize wavelength combination and initial power of each area through an intelligent terminal, the different maintenance requirements of alopecia and early white hair in different areas are met, and single-area or multi-area collaborative phototherapy can be achieved.

The invention provides a herbal composition for preventing hair loss and promoting hair growth as well as a preparation method and application thereof, the herbal composition for preventing hair loss and promoting hair growth comprises a herbal extract, and the herbal extract is obtained by extracting a herbal mixture, the herbal mixture comprises ginseng, ganoderma atrum, radix polygoni multiflori preparata, prepared rehmannia root, ligusticum wallichii, angelica sinensis, gallnut, cacumen biotae, small yellow ginger, salvia miltiorrhiza, eclipta prostrata, glossy privet fruit, camellia seed, moutan bark, soapberry, gleditsia sinensis, folium artemisiae argyi, folium mori, senecio scandens, honeysuckle, fructus psoraleae, emblic leafflower fruit, radix sophorae flavescentis, fructus cnidii, euphorbia thymifolia, Chinese knotweed herb, duckweed, aloe juice, elm bark, agilawood, cortex dictamni and mint leaf. According to the herbal composition for preventing alopecia and growing hair, various components in the herbal extract are compounded to achieve a synergistic effect, scalp is deeply cleaned and nourished, scalp blood circulation is promoted, hair follicles are activated, hair roots are strengthened, and the herbal composition has the effects of preventing alopecia and growing hair, protecting and blackening hair, controlling oil and supplementing water, removing dandruff and relieving itching.

The invention discloses a traditional Chinese medicine composition of hair cleaning, nourishing and strengthening shampoo and hair care essence and a preparation method of the traditional Chinese medicine composition. According to the hair cleaning, nourishing and strengthening shampoo, the multiple hair care effects are achieved through the synergistic effect of the saponin, the soapberry, the folium mori and the cortex phellodendri. The Chinese honeylocust fruit and the Chinese soapberry fruit are used as natural cleaning components and can mildly remove redundant grease and dirt on the scalp, and hair follicle blockage is avoided; the folium mori and the cortex phellodendri play roles in clearing heat and drying dampness, reducing excessive secretion of sebaceous gland and radically relieving the problem of greasy scalp, and the hair care essence adopts compatibility of multiple traditional Chinese medicines such as fructus cnidii, fructus kochiae, cortex dictamni and radix sophorae flavescentis to form a comprehensive scalp care system. The fructus cnidii and the fructus kochiae can inhibit harmful flora of scalp, improve the unbalance state of the flora and relieve scalp itching; cortex dictamni and radix sophorae flavescentis further enhance the antibacterial effect and reduce inflammatory response. The Chinese arborvitae twig, the prepared fleece-flower root, the eclipta and other components have a synergistic effect, so that the hair follicle can be nourished, the scalp blood circulation can be promoted, the hair root fixation force can be enhanced, and the alopecia can be reduced.

The compositions and methods provided herein include a pharmaceutical formulation for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Also provided herein are pharmaceutical formulations for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof and one or more additional active agents. Also provided herein are methods of treating hair loss by administering to a subject in need thereof a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Further provided herein is a kit including a slow modified release vehicle comprising oral minoxidil or a pharmaceutically acceptable salt thereof.

The application belongs to the technical field of medical image processing and diagnosis, and particularly relates to an improved RCN-based alopecia typing and grading intelligent identification method and system, wherein alopecia image data is acquired, a U-Net++ model is trained, hair probability distribution is obtained, a hair mask is generated, an alopecia region is segmented, and continuous frame images are generated through SIFT feature matching and affine transformation; spatiotemporal joint features are extracted by using an improved RCN network, combined with a ResNet-50 backbone network, to generate alopecia local feature maps, spatiotemporal self-attention encoders and double-path attention architectures are fused, through a dynamic weight distribution mechanism, key hair growth regions are located and hair growth directions are analyzed, and density change trends are obtained; through an ensemble learning model, alopecia density and grade are identified, health is scored, and a heat map is generated to label hair follicle atrophy regions. Thus, the problems of weak feature expression ability, poor scene adaptability and insufficient positioning accuracy in the prior art are solved.

The present invention relates to a cosmetic composition comprising 2,4-diaminopyrimidine-3-N-oxide and / or one of its organic or mineral acid salts and / or one of its hydrates, piroctone olamine, niacinamide, and at least 1% by weight of a particular hydroxylated compound. The invention also relates to a cosmetic treatment method for human keratinous materials such as skin, particularly scalp, hair, and / or eyelashes, comprising at least the application of the cosmetic composition according to the present invention. The present invention further relates to the use of said cosmetic composition to treat hair loss and / or promote the regrowth of keratin fibers.

1. The name of the design product: hair growth cap. 2. The use of the design product: for treating hair loss and promoting hair growth. 3. The design points of the design product: in shape. 4. The picture or photo that best shows the design points: perspective view.

This application relates to the field of shampoo bar technology, and more particularly to a traditional Chinese medicine shampoo bar and its preparation method. The traditional Chinese medicine shampoo bar includes active components of traditional Chinese medicine and basic raw materials for forming the soap body; the active components of traditional Chinese medicine are formed by soaking, decocting, and filtering the following raw materials in the indicated weight ratios: Platycladus orientalis leaves, dried ginger, chrysanthemum, Sapindus mukorossi, Gleditsia sinensis, duckweed, Eclipta prostrata, Ligustrum lucidum, processed Polygonum multiflorum, Sophora flavescens, Kuding tea, peppermint, Artemisia argyi, ginseng, Ganoderma lucidum, Angelica sinensis, mulberry leaves, and Perilla frutescens; wherein, the decoction solvent for the raw materials is rice water. The traditional Chinese medicine shampoo bar formula provided in this application is entirely made from traditional Chinese herbs, has high safety, and has the advantages of effectively cleaning the scalp, preventing hair loss, promoting hair growth, and darkening and brightening hair, effectively solving problems such as oily scalp, itchy scalp, acne on the scalp, increased dandruff, hair loss, and gray hair. The preparation process can maximize the extraction of the effective components of traditional Chinese medicine and can be mass-produced.

The invention provides a separation and purification process of active ingredients of polygonum multiflorum, and belongs to the technical field of plant extraction. The separation and purification process comprises the steps of ethanol ultrasonic extraction of polygonum multiflorum, activated carbon adsorption, HPD-100 macroporous resin purification, membrane filtration, ultrafiltration, vacuum concentration and crystallization, and the polygonum multiflorum extract with high 5alpha-reductase inhibitory activity can be efficiently extracted. The anti-hair loss effect can be obviously enhanced after the compound is compounded with the eucommia ulmoides vine extract obtained through specific microbial fermentation. In-vitro experiment results show that both the polygonum multiflorum extract and the eucommia ulmoides vine extract have remarkable 5alpha-reductase inhibitory activity. The anti-hair loss composition can effectively promote hair growth and improve the hair loss condition, and the effect of the anti-hair loss composition is close to that of a positive control drug. The process is stable, the purity is high, the activity is strong, the method is suitable for industrial production, and the market application prospect is good.

The invention discloses an enzyme-containing anti-inflammatory composition for pet skin and hair follicle health. The enzyme-containing anti-inflammatory composition comprises an enzyme preparation, a hair follicle maintenance agent, a functional auxiliary agent and a carrier raw material. The core innovation lies in that a hair follicle targeted enzymolysis technology is adopted, and a specific enzyme modified by polyethylene glycol can efficiently dredge hair follicles; the anti-inflammatory and hair follicle repairing dual effects are achieved through anti-inflammatory-maintenance synergistic matching and adding sequence optimization; the damaged barrier is rapidly repaired by combining a composite barrier repairing agent and a gradient permeation process; enzyme activity and mildness are guaranteed by adopting a microcapsule embedding and low-temperature preparation technology. The composition can specifically solve the problems of hair follicle blockage, inflammation and unhairing, is suitable for pets of all ages and skin types, and is high in practicability.

This disclosure provides a method for treating hair loss in a subject requiring treatment for hair loss, comprising topically administering an effective amount of cortexolone-17α-propionate and an effective amount of minoxidil to the subject. This disclosure further provides a topical pharmaceutical formulation comprising cortexolone-17α-propionate, minoxidil, and one or more pharmaceutically acceptable carriers.

Bioactive walnut peptides and use of the bioactive walnut peptides for topical application to the scalp are described. The bioactive walnut peptides may be incorporated into a pharmaceutical or cosmetic composition for application to the scalp. The pharmaceutical or cosmetic compositions and the one or more bioactive walnut peptides in the compositions are particularly useful for treating or preventing hair loss, and treating scalp conditions, such as dandruff, scalp psoriasis, and acne.

The invention relates to an anti-hair-loss washing and caring composition containing broadleaf holly leaf and Chinese ilex leaf extract and a preparation method, the anti-hair-loss washing and caring composition comprises shampoo and a hair conditioner, and the shampoo and / or the hair conditioner contains the broadleaf holly leaf and Chinese ilex leaf extract; the folium llicis latifoliae and Chinese ilex leaf extract is added into the shampoo or the hair conditioner, so that the anti-hair loss effect of the folium llicis latifoliae and Chinese ilex leaf extract can be exerted when the shampoo or the hair conditioner is used; the weight ratio of the broadleaf holly leaf and Chinese ilex leaf extract is 0.05%-10%. The folium llicis latifoliae and Chinese ilex leaf extract is added into the shampoo and the hair conditioner, so that the effects of promoting hair growth and inhibiting alopecia can be achieved after long-term use, and a better effect can be achieved after matched use.

The compositions and methods provided herein include a pharmaceutical formulation for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Also provided herein are pharmaceutical formulations for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof and one or more additional active agents. Also provided herein are methods of treating hair loss by administering to a subject in need thereof a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Further provided herein is a kit including a slow modified release vehicle comprising oral minoxidil or a pharmaceutically acceptable salt thereof.

The invention discloses a nutrient solution for promoting hair growth. The nutrient solution is a supernatant which is collected after hair follicle stem cells are subjected to cell culture. The invention can promote hair production and solve the problem of alopecia. The invention also discloses a comb for applying the nutrient solution to the skin.

The compositions and methods provided herein include a pharmaceutical formulation for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Also provided herein are pharmaceutical formulations for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof and one or more additional active agents. Also provided herein are methods of treating hair loss by administering to a subject in need thereof a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Further provided herein is a kit including a slow modified release vehicle comprising oral minoxidil or a pharmaceutically acceptable salt thereof.

The compositions and methods provided herein include a pharmaceutical formulation for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Also provided herein are pharmaceutical formulations for oral administration comprising a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof and one or more additional active agents. Also provided herein are methods of treating hair loss by administering to a subject in need thereof a daily dose of a modified release formulation of minoxidil or a pharmaceutically acceptable salt thereof. Further provided herein is a kit including a slow modified release vehicle comprising oral minoxidil or a pharmaceutically acceptable salt thereof.

This invention relates to the field of biomedicine, and more particularly to a hair follicle-targeted delivery system and a hair growth and anti-hair loss cosmetic. The hair follicle-targeted delivery system comprises: a lipid nanoparticle core loaded with bioactive ingredients having hair growth and anti-hair loss effects; a hair follicle-targeting molecule capable of specifically recognizing and binding to receptors on the surface of hair follicle cells; and a targeting and anchoring conjugate consisting of a linker covalently linked to the hair follicle-targeting molecule and an anchoring lipid. The targeting and anchoring conjugate is embedded in the lipid bilayer of the lipid nanoparticle core via the anchoring lipid, thereby exposing the hair follicle-targeting molecule on the surface of the lipid nanoparticle core. This application, through its innovative targeting and anchoring conjugate structure, can significantly improve the targeting and enrichment efficiency of the hair growth and anti-hair loss active ingredients on hair follicle tissue, ensuring precise drug action on the lesion site, thereby significantly increasing the number of hair follicles in the alopecia areata modeling area.

The invention relates to the field of hair loss preventing and hair growing compositions, in particular to a Tibetan medicine composition for preventing hair loss and growing hair and application of the Tibetan medicine composition. The invention discloses a traditional Chinese medicine with the effects of tonifying liver and kidney, reinforcing qi and nourishing blood, cooling blood and dispelling wind, and clearing heat and eliminating dampness. The traditional Chinese medicine is mainly prepared from the following raw medicinal materials: emblic leafflower fruit, cassia seed, abelmoschus esculentus seed, catechu, acorus calamus, frankincense, codonopsis pilosula, platycladus orientalis, medlar, black sesame, dendrobe and dried ginger. The channel tropism of the medicines in the formula is basically and directly related to the liver and kidney, and the medicines are combined to achieve the good functions of tonifying the liver and kidney and replenishing qi and blood.

The present disclosure concerns a polymer selected from poly-L-lactic acid, poly-D, L-lactic acid and any copolymer comprising repeating units comprising L-lactic acid, or any combination thereof, for use in preventing and / or treating any damage, disease, illness, and / or condition characterized by hair loss. Compositions comprising said polymer are also disclosed for said use.

Cosmetic products containing specific amounts of adenosine and at least one pentose in a cosmetic carrier are suitable for the treatment of hair and / or scalp and lead to - Revitalization of the hair and / or - Stimulation / activation of energy metabolism in hair follicles / hair roots and / or - Stimulation / enhancement of hair growth and / or - Prevention / reduction of premature hair loss and / or - Delaying scalp aging and / or - Increased keratin synthesis and / or - Improvement of the tensile strength of keratin fibers.