The invention relates to the technical field of Bluetooth headset communication, in particular to a device master-slave role switching system and method for wireless communication, and the method comprises the steps: S100, building a monitoring link for the communication between a master device and a host device; s200, when role switching between the master device and the slave device is triggered, switching the master device to the slave device; any one of the master device and the slave device initiates a role exchange request through a monitoring link; the method comprises the steps that arole interchange request is received, a role interchange time point is appointed in the role interchange request, the other party replies a received request confirmation packet for receiving the roleinterchange request through a monitoring link, the system comprises a master device, a slave device and a host device, the master device comprises a master processing module, and the slave device comprises a slave processing module. According to the invention, the roles of the master device and the slave device are interchanged, so that the energy consumption of the two devices tends to be consistent, the service life of the devices is prolonged, and the user experience is improved.