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7798results about How to "Promote regeneration" patented technology
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Porous tissue scaffoldings for the repair of regeneration of tissue
InactiveUS6333029B1Promote growthPromote regenerationPeptide/protein ingredientsAntipyreticRepair tissueOpen cell
Owner:ETHICON ENDO SURGERY INC
Compressed high density fibrous polymers suitable for implant
Owner:DSM IP ASSETS BV
Catalyzed SCR filter and emission treatment system
ActiveUS7229597B2Reduce the temperaturePromote regenerationCombination devicesLiquid degasification with auxillary substancesNitrogen oxideSoot
Owner:BASF CORP
Catalyzed SCR filter and emission treatment system
ActiveUS20050031514A1Reduce the temperaturePromote regenerationCombination devicesLiquid degasification with auxillary substancesChemistryCompound (substance)
Provided is an emission treatment system and method for simultaneously remediating the nitrogen oxides (NOx), particulate matter, and gaseous hydrocarbons present in diesel engine exhaust streams. The emission treatment system has an oxidation catalyst upstream of a soot filter coated with a material effective in the Selective Catalytic Reduction (SCR) of NOx by a reductant, e.g., ammonia. Also provided is a method for disposing an SCR catalyst composition on a wall flow monolith that provides adequate catalyst loading, but does not result in unsuitable back pressures in the exhaust.
Owner:BASF CORP
Systems, devices and methods for treatment of intervertebral disorders
InactiveUS20060149380A1Increase heightMinimally invasiveSuture equipmentsSpinal implantsFiberElastomer
A bioactive / biodegradable nucleus implant for repairing degenerated intervertebral discs that is inflated inside the nucleus space after the degenerated nucleus has been removed to re-pressurize the nuclear space within the intervertebral disc. The implant is inflated with a high molecular weight fluid, gel or combination of fluid and elastomer, preferably an under-hydrated HA hydrogel / growth factor mixture with or without host cells. The implant includes an internal, integral, self-sealing valve that allows one-way filling of the implant after it is placed within the disc, and is made from a material that allows fibrous in growth thereby stabilizing the implant. A variety of substances can be incorporated into the implant to promote healing, prevent infection, or arrest pain.
Owner:RGT UNIV OF CALIFORNIA
Biologic replacement for fibrin clot
InactiveUS20040059416A1Promote regenerationWound closure is subsequentlySuture equipmentsVirusesLigament structureBiomedical engineering
Owner:CHILDRENS MEDICAL CENT CORP +1
Usage of Extracorporeal and Intracorporeal Pressure Shock Waves in Medicine
ActiveUS20110034832A1Reduce inflammationPromote nerve regenerationUltrasound therapyPneumatic massageMedicineFocal volume
A shock wave applicator includes a shock wave generator and an asymmetrical reflector portion in a housing. Asymmetry of the reflector portion is combined with one or more wave generators to produce a variety of focal volumes and wave fronts for medical treatment.
Owner:SANUWAVE INC
Solid sorbents for removal of carbon dioxide from gas streams at low temperatures
InactiveUS6908497B1Promote regenerationRegeneration process is inexpensiveGas treatmentOther chemical processesGas solidSorbent
New low-cost CO2 sorbents are provided that can be used in large-scale gas-solid processes. A new method is provided for making these sorbents that involves treating substrates with an amine and / or an ether so that the amine and / or ether comprise at least 50 wt. percent of the sorbent. The sorbent acts by capturing compounds contained in gaseous fluids via chemisorption and / or physisorption between the unit layers of the substrate's lattice where the polar amine liquids and solids and / or polar ether liquids and solids are located. The method eliminates the need for high surface area supports and polymeric materials for the preparation of CO2 capture systems, and provides sorbents with absorption capabilities that are independent of the sorbents' surface areas. The sorbents can be regenerated by heating at temperatures in excess of 35° C.
Owner:ENERGY U S DEPARMENT OF
Stent for a vascular meniscal repair and regeneration
ActiveUS20070067025A1Promote healingPromote regenerationStentsAdditive manufacturing apparatusMeniscal repairVascular tissue
A surgical stent made of biocompatible material for implantation in human tissue to enable blood and nutrients to flow from an area of vascular tissue to an area of tissue with little or no vasculature.
Owner:HOWMEDICA OSTEONICS CORP
Non-destructive tissue repair and regeneration
ActiveUS20070185568A1Facilitate healing and regenerationEasy to fixStentsAdditive manufacturing apparatusNon destructiveTissue repair
Owner:HOWMEDICA OSTEONICS CORP
Cellular fibronectin as a diagnostic marker in stroke and methods of use thereof
InactiveUS20050130230A1Rapidly and accurately determinedMaximal sensitivityBiostatisticsDisease diagnosisStroke treatmentAssay
The present invention relates to methods for the diagnosis and evaluation of stroke and stroke sub-type. A variety of bio-markers are disclosed for assembling a panel for such diagnosis and evaluation. Methods are disclosed for selecting markers and correlating their combined levels with a clinical outcome of interest. In various aspects: the invention provides methods for early detection and differentiation of stroke subtypes, for determining the prognosis of a patient presenting with stroke symptoms, and identifying a patient at risk for hemorrhagic transformation after thrombolyic therapy. Methods are disclosed that provide rapid, sensitive and specific assays to greatly increase the number of patients that can receive beneficial stroke treatment and therapy, and reduce the costs associated with incorrect stroke diagnosis.
Owner:PREDICTION SCI
Methods and apparatus for enhanced and controlled delivery of a biologically active agent into the central nervous system of a mammal
InactiveUS7033598B2Enhanced and controlled deliveryReduce applicationsElectrotherapyPharmaceutical delivery mechanismNervous systemActive agent
Disclosed are invasive and non-invasive central nervous system (CNS) drug delivery methods and devices for use in these methods that essentially circumvent the blood-brain barrier. More specifically, the disclosed methods and devices utilize iontophoresis as delivery technique that allows for enhanced delivery of a biologically active agent into the CNS of a mammal as well as for (pre)-programmable and controlled transport.
Owner:INTRABRAIN INT
Method for treatment of defects in the intervertebral disc
InactiveUS20050069571A1Easy to processPromote regenerationBiocideJoint implantsIntervertebral discDefect repair
A minimally invasive spinal disc defect repair method is disclosed. The method relates to insertion of disc defect repair materials that are substantially two-dimensionally shaped and which allow for insertion and preferably self retention within the disc defect with plugging of the annulus fibrosis.
Owner:DEPUY ACROMED INC
Composition for promotion of bone growth and maintenance of bone health
InactiveUS20050079232A1Accelerate bone regenerationInhibit bone resorptionBiocideNon-fibrous pulp additionDiseaseBone growth
The present invention relates to a composition for maintenance of bone health or prevention, alleviation and / or treatment of bone disorders. It also relates to the use of the composition in the manufacture of a nutritional product, a supplement, a treat or a medicament; and a method of promoting bone growth or for the maintenance of bone health, which comprises administering an effective amount of the composition.
Owner:NESTEC SA
Functionalized derivatives of hyaluronic acid, formation of hydrogels in situ using same, and methods for making and using same
InactiveUS6630457B1Assay sensitivityPromote regenerationOrganic active ingredientsBiocideDrug deliveryTissue adhesives
Methods for chemical modification of hyaluronic acid, formation of amine or aldehyde functionalized hyaluronic acid, and the cross-linking thereof to form hydrogels are provided. Functionalized hyaluronic acid hydrogels of this invention can be polymerized in situ, are biodegradable, and can serve as a tissue adhesive, a tissue separator, a drug delivery system, a matrix for cell cultures, and a temporary scaffold for tissue regeneration.
Owner:ORTHOGENE
Biologic replacement for fibrin clot
InactiveUS6964685B2Increase contactResists premature degradationSurgical adhesivesPeptide/protein ingredientsExtra-ArticularExtracellular proteins
Owner:CHILDRENS MEDICAL CENT CORP
Compressed high density fibrous polymers suitable for implant
An embodiment of the present invention may be made by the following steps: providing a mixture comprising a plurality of fibers, a lubricant, and a suspension fluid, with the suspension fluid filling a void space between said fibers and subjecting said mixture to at least one compressive force. The compressive force causes the migration and alignment of said fibers; and may remove substantially all of the suspension fluid from said mixture. The mixture may further comprise a biologically active agent, or a reinforcing agent.
Owner:DSM IP ASSETS BV
Injectable cross-linked polymeric preparations and uses thereof
InactiveUS20050003010A1Promote regenerationFunction increaseOrganic active ingredientsPowder deliveryCross-linkDamages tissue
A composition for promoting repair of damaged tissues, being a cross-linked alginate solution, which can be maintained in liquid form indefinitely (under constant conditions) and only gels in vivo. This cross-linked alginate solution is an ideal material to be used for tissue repair. Injection of said material into cardiac tissue post-myocardial infarct induced tissue regeneration. The invention provides such injectable solution, as well as compositions and method of preparation thereof. The invention also provides various methods and uses of the cross-linked alginate solution, for cardiac tissue regeneration, induction of neo-vascularization, enhancing SDF-1 expression and guiding stem cell chemotaxis, among others. A kit for tissue repair is also provided.
Owner:BEN GURION UNIVERSITY OF THE NEGEV
Biologic replacement for fibrin clot
InactiveUS20020123805A1Promote regenerationLess invasive treatmentSurgical adhesivesPeptide/protein ingredientsMedicineLigament
Owner:CHILDRENS MEDICAL CENT CORP
Hydrogels for orthopedic repair
InactiveUS7008635B1Effective treatmentGood biocompatibilityPowder deliveryOintment deliveryPorosityTarget tissue
Hydrogels intended for orthopedic applications, including repair and regeneration of cartilage, bone, joint surfaces and related tissues, must possess greater strength and toughness than hydrogels used in soft tissue repair. A hydrogel formulation is provided which has high strength, toughness, a suitable mechanical modulus and low equilibrium hydration. It may also have controlled porosity or degradation time. It can be made to polymerize in situ with high (“good” to “excellent”) adherence to target tissue or surfaces. A preferred formulation for forming such gels comprises 40 to 80% by weight of a low-molecular weight polar monomer and 30 to 10% of a hydrophilic macromeric crosslinker.
Owner:GENZYME CORP
Human Delta3 nucleic acid molecules
InactiveUS6121045AEffective treatmentModulating level of proteinNervous disorderBacteriaMolecular biologyNucleic acid molecule
The invention provides nucleic acid molecules which encode polypeptides having homology to proteins in the Delta family of proteins. The invention also provides vectors containing nucleic acid molecules of the invention and host cells containing the vectors.
Owner:MILLENNIUM PHARMA INC
Nucleus Anti-expulsion devices and methods
ActiveUS20080097611A1Prevent expulsionAvoid expulsionSpinal implantsBiomedical engineeringReplacement implant
Devices and methods for preventing the migration or expulsion of a nucleus disc replacement implant are provided. In one embodiment, an anti-expulsion device includes a body that is movable between a compressed configuration where it is adapted to fit through an opening in an annulus of a spinal disc, and an expanded configuration where it has a size that is larger than a size of the opening in the annulus of a spinal disc. The body can also include one or more mating features that allow the body to interact with a nucleus disc replacement implant and / or an annular wall of an annulus. As a result, since the body is larger than the opening of the annulus in the expanded configuration, the interlocking connection between the body and the nucleus disc replacement implant and / or annular wall will allow the body to prevent the nucleus disc replacement implant from being expulsed from the opening in the annulus.
Owner:DEPUY SYNTHES PROD INC
Methods for assisting recovery of damaged brain and spinal cord using arrays of X-ray microplanar beams
ActiveUS7158607B2Promote regenerationMaximum functionX-ray/gamma-ray/particle-irradiation therapyIrradiation devicesX-rayInjury Site
Owner:WASHINGTON UNIV IN SAINT LOUIS +1
Intramedullary nail system and method for fixation of a fractured bone
InactiveUS20050010223A1Prevent rotationPrevent longitudinal movementInternal osteosythesisJoint implantsMedicineLocking mechanism
Apparatus for treating a fracture of a bone of a subject includes an intramedullary (IM) nail, adapted to be inserted in a medullary canal of the bone of the subject, and having a proximal head that defines at least one hole therethrough. The apparatus also includes a sleeve, which includes a locking mechanism, which locking mechanism is adapted to engage the hole when the sleeve is inserted in the hole, such engagement preventing rotational and longitudinal movement between the sleeve and the hole. In an embodiment, the apparatus includes a screw, the sleeve being adapted to slidably receive the screw.
Owner:GOTFRIED YECHIEL
Method and composition for repairing and promoting regeneration of mucosal tissue in the gastrointestinal tract
InactiveUS6685971B2Restore physiological structure and functionPromote general health of whole bodyBiocideAerosol deliveryDiseaseAdditive ingredient
The present invention provides novel compositions and methods for protecting and promoting cell growth and restoring physiological structure and function to mucosal tissue of the body, especially mucosa in the gastrointestinal tract. The composition can be used as a pharmaceutical or nutraceutical to treat a gastrointestinal disorder or to promote general health of an animal, preferably a human. The composition is in an oral dosage form and comprises edible oil homogenized with a sterol compound at a concentration of at least 0.5% by weight and edible wax at a concentration ranging from 3% to 30% by weight. The composition can also be used to deliver other active ingredients to the gastrointestinal tract for treating various diseases.
Owner:XU RONGXIANG
Production method of concave convex stick ceramic grain filter
InactiveCN100423808CGood film-hanging performanceImprove stabilityFiltration separationClaywaresRough surfaceWater quality
Owner:许盛英
Fabrication and use of biocompatible materials for treating and repairing herniated spinal discs
InactiveUS20070005140A1Easy to approachEasy to performInternal osteosythesisPharmaceutical delivery mechanismCell bindingHigh probability
The present invention involves the fabrication and use of biocompatible polymers that are injected percutaneously into the inner portion of a defective region of a spinal disc and swell or expand or subsequently cure in situ to form a disc nucleus prosthesis. The polymers may be synthetic or natural (e.g., collagen), and may be provided in forms including, but not limited to hydrogels, compressible foams, cords, balloons, etc. Subsequent to injection into a target space or void within the disc, one or more cell binding agents, growth factors, and / or drugs on or within the cured polymer then interact with the remaining portion of the disc to support tissue ingrowth and to achieve a higher probability of biological mimicking.
Owner:SANDFORD UNIV
Extracorporeal pressure shock wave device
ActiveUS8556813B2Reduce edemaReduce inflammationUltrasonic/sonic/infrasonic diagnosticsUltrasound therapyAcousticsFocal volume
Owner:SANUWAVE INC
Evolution of whole cells and organisms by recursive sequence recombination
InactiveUS8377681B2Prediction of efficacyIncrease diversityFungiMicrobiological testing/measurementMetaboliteEntire cell
Owner:CODEXIS MAYFLOWER HLDG LLC
Porous tissue scaffoldings for the repair or regeneration of tissue
InactiveUS20010033857A1Facilitate growthFacilitate growth or regeneration of tissueBiocidePowder deliveryChemistryTissue engineering
The present patent describes a three-dimensional interconnected open cell porous foams that have a gradient in composition and / or microstructure through one or more directions. These foams can be made from a blend of absorbable and biocompatible polymers that are formed into foams having a compositional gradient transitioning from predominately one polymeric material to predominately a second polymeric material. These gradient foams are particularly well suited to tissue engineering applications and can be designed to mimic tissue transition or interface zones.
Owner:ETHICON ENDO SURGERY INC
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