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565 results about "Intervertebral disc" patented technology

An intervertebral disc (or intervertebral fibrocartilage) lies between adjacent vertebrae in the vertebral column. Each disc forms a fibrocartilaginous joint (a symphysis), to allow slight movement of the vertebrae, to act as a ligament to hold the vertebrae together, and to function as a shock absorber for the spine.

In-vitro bionic mechanical test system and method for spinal skeletal muscle

The invention discloses an in-vitro bionic mechanical testing system and method for spinal skeletal muscles, and particularly relates to the field of mechanical testing, and the system comprises a bionic construction module, a finite element modeling module, a multi-axis mechanical loading module, an iterative calculation module and a correction module; through modular design, the system comprises a vertebral body unit, an intervertebral disc simulation assembly and a skeletal muscle simulation unit, each assembly is customized according to anatomical features of a human body, a finite element modeling module is utilized to generate a three-dimensional model, a multi-directional mechanical load is applied, and response data is collected; experimental data are input into the finite element model for iterative calculation, so that stress distribution, a strain field and kinematic deviation are compared; if the error exceeds a preset threshold value, the model parameters and the physical parameters are corrected until the experiment and simulation results converge; and finally, based on the optimized finite element model, predicting a failure mechanism of the spinal skeletal muscle under a complex load, and evaluating the risks of fracture, hairline fracture, nucleus pulposus protrusion and muscle strain.
Owner:FOURTH MILITARY MEDICAL UNIVERSITY

CT image segmentation method for spine surgery

The invention discloses a CT image segmentation method for spine surgery, and relates to the technical field of medical image processing, and the method comprises the steps: obtaining a spine CT image of a patient, and carrying out the preprocessing of the spine CT image; adopting a centrum gap detection method to detect a centrum gap region of a spine in the preprocessed CT image, and performing automatic segmentation on each centrum based on centrum gap region information to obtain a preliminary segmentation result of the centrum; extracting local texture features of the intervertebral disc and the nerve root in the intervertebral space area, and classifying the local texture features through a classifier to generate a preliminary segmentation result of the intervertebral disc and the nerve root; performing rigid registration and non-rigid registration on the initial segmentation results of the vertebral body, the intervertebral disc and the nerve root and the standard three-dimensional model, and identifying an abnormal region in segmentation; by extracting local texture features of the intervertebral disc and the nerve root and combining a support vector machine classifier, accurate segmentation of various structures can be realized.
Owner:南昌大学第一附属医院

Multi-shield spinal access system

An access device for accessing an intervertebral disc having an outer shield comprising an access shield with a larger diameter (˜16-30 mm) that reaches from the skin down to the facet line, with an inner shield having a second smaller diameter (˜5-12 mm) extending past the access shield and reaches down to the disc level. This combines the benefits of the direct visual microsurgical / mini open approaches and the percutaneous, “ultra-MIS” techniques.
Owner:MEDOS INT SARL

Patient-bone-customized cervical vertebra fixing plate using 3D printing technology

The objective of the present invention is to provide a patient-bone-customized cervical vertebra fixing plate using 3D printing technology, the cervical vertebra fixing plate having a screw separation blocking plate rotatably formed thereon so as to prevent the pushing outward of a screw inserted into and fastened to the cervical vertebra from the cervical vertebra fixing plate such that the fixing state of the cervical vertebra fixing plate can be firmly maintained, and also having an uneven part or a porous structure layer for improving adhesion to the cervical vertebrae so that the cervical vertebra fixing plate can be firmly adhered, without deviation from the position thereof, to the cervical vertebrae between which an artificial disc is inserted, and enabling adhesion and coupling force between the inner surface of the cervical vertebra fixing plate and the surface of the cervical vertebra to be improved.
Owner:ACE MEDICORP CO LTD

Spine image recognition method and related equipment

The embodiment of the invention provides a spine image recognition method and related equipment. The spine image recognition comprises the following steps: acquiring a spine image to be detected, and preprocessing the spine image to be detected to obtain a target spine image; the target spine image is input into a key point recognition model, position information output by the key point recognition model for each section of vertebral body in the target spine image is obtained, and the position information is marked on the target spine image and at least comprises positioning frame information, a vertebral body name and angular point coordinates; the key point identification model comprises a CBAM module; correcting and adjusting the position information to obtain corrected position information; and performing intervertebral disc positioning and vertebra identification according to the corrected position information. According to the technical scheme, the improved key point recognition model is adopted, the positioning frame, the cone name and the angular point coordinates are directly output without depending on a segmentation model, the process is simplified, and the detection speed and robustness are improved.
Owner:BEIJING WANDONG MEDICAL TECH CO LTD

Spinal surgery method

A discectomy method entails removing at least a portion of a spinal lamina to form an access path in a patient. A surgical instrument is inserted along the path and a distal end of the instrument is placed in operative contact with herniated or bulging disc material of a spinal disc. The instrument is operated to remove the herniated or bulging disc material, to thereby space a remaining portion of the spinal disc from spinal nerves. A tip of an ultrasonic surgical probe is then placed into contact with an outer surface of the remaining portion of the spinal disc, and an ultrasonic mechanical standing wave generated in the probe while maintaining the operative tip in contact with the outer surface to harden the wall surface and thereby reduce chances of disc herniation at the outer surface.
Owner:MISONIX INC

Automatic generation method of cervical vertebra disease rehabilitation prescription

The invention specifically discloses an automatic generation method for a cervical vertebra disease rehabilitation prescription, and the method comprises the steps: constructing a cervical vertebra image feature automatic measurement system based on computer vision and deep learning, so as to monitor the training motion quality of a patient in real time, and obtaining the kinematics parameters of rehabilitation exercise training; acquiring a medical image and clinical data of a patient, and standardizing the medical image to construct a standard space of a multi-modal medical image; performing automatic segmentation and anatomical structure calibration on a vertebral body-intervertebral disc based on the standard space to obtain fusion image features; and constructing a multi-modal hierarchical decision model fusing the image features, the kinematics parameters and the clinical data to carry out quantitative analysis on pathological feature parameters, and outputting a standardized illness state assessment result conforming to international clinical guidelines. The dynamic optimization of the treatment scheme can be realized through a feedback mechanism, and the treatment effect is improved.
Owner:PEKING UNION MEDICAL COLLEGE HOSPITAL +1

Four-dimensional lumbar vertebra traction bed with fixed-point massage function and working method of four-dimensional lumbar vertebra traction bed

The invention relates to the technical field of traction treatment, in particular to a four-dimensional lumbar vertebra traction bed with a fixed-point massage function and a working method thereof, and the four-dimensional lumbar vertebra traction bed comprises an upper half bed body, a traction bed frame, a swinging bed frame, a rotating bed frame, an angulation bed frame and a massage mechanism; particularly, horizontal traction, flexion and extension traction, lateral flexion traction and rotary traction of the waist are achieved through three electric push rods, a traction motor and a rotary motor. Four-dimensional traction of the waist is achieved, and the traction effect is improved. And a massage mechanism is arranged below the waist, so that horizontal traction is realized, and waist massage is carried out at the same time. And the intervertebral disc tissue protrusion of the patient can be easily recovered and reset.
Owner:FUZHOU UNIV

Patient-specific spinal fusion devices and associated systems and methods

The present technology includes patient-specific spinal fusion devices, which may include an interbody implant that is designed to be positioned within a disc space between two vertebral bodies and one or more fixation elements that can anchor the interbody implant to the vertebral bodies. The fusion devices include one or more retention mechanisms for retaining the fixation elements within corresponding lumens or bore holes extending through the interbody implant. Methods for designing and manufacturing patient-specific spinal fusion devices are also described herein.
Owner:CARLSMED INC

Multi-shield spinal access system

An access device for accessing an intervertebral disc having an outer shield comprising an access shield with a larger diameter (˜16-30 mm) that reaches from the skin down to the facet line, with an inner shield having a second smaller diameter (˜5-12 mm) extending past the access shield and reaches down to the disc level. This combines the benefits of the direct visual microsurgical / mini open approaches and the percutaneous, “ultra-MIS” techniques.
Owner:MEDOS INT SARL

Device for constructing intervertebral disc degeneration model by using mouse simulation

The invention provides a device for constructing an intervertebral disc degeneration model by using mouse simulation, and belongs to the technical field of medical research. Comprising a mounting base plate, a supporting rod is connected to the middle of the top of the mounting base plate, a top seat is fixedly connected to the top of the supporting rod, and a ring seat is fixedly connected to the inner side of the top seat. The body clamping mechanism can accurately clamp an animal body, is matched with an electric push rod to realize bending or unfolding of the body, and is matched with the limb positioning mechanism to improve the experiment suitability and assist in simulating the pathological process of human intervertebral disc degeneration, the limb positioning mechanism fixes the limbs of the animal through antiskid plates, and the device can adapt to animals with different sizes and is high in practicability. The rotating shaft design avoids animal limb fracture, the angle adjusting assembly and the arc-shaped displacement assembly enable the animal limbs to flexibly swing and move up and down, the convenience and the adjusting adaptation performance of the device are improved, and more accurate data and reliable experiment conditions are provided for lumbar vertebra pathological research on the whole.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Lumbar intervertebral disc herniation identification method and system based on CT image

The invention discloses a lumbar disc herniation identification method and system based on a CT image, and the method comprises the steps: carrying out the multi-dimensional projection slice processing of input CT image data, and obtaining a multi-dimensional feature projection slice image data set; according to the multi-dimensional feature projection slice image data set, constructing an adaptive expansion bounding box model, and automatically generating a segmentation boundary of the lumbar intervertebral disc by using a nonlinear constraint iteration function to obtain a lumbar intervertebral disc three-dimensional voxel model of a target segmentation area; for the lumbar intervertebral disc three-dimensional voxel model, outputting a high-dimensional lumbar vertebra texture feature vector by using a fiber enhanced tensor network; and according to the high-dimensional lumbar vertebra texture feature vector, combining anatomical appearance features of the lumbar intervertebral disc at different positions in the multi-dimensional projection slice to construct a multi-dimensional fusion label classification model so as to output a normal or protruding identification result of the lumbar intervertebral disc. According to the embodiment of the invention, modern image processing and deep learning technologies can be combined, and the recognition rate and accuracy of lumbar disc herniation can be effectively improved.
Owner:HANGZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL (HANGZHOU TRADITIONAL CHINESE MEDICINE HOSPITAL AFFILIATED TO ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE)

System and Method for Simulating Intervertebral Discs

The present invention provides a method of simulating an intervertebral disc, comprising: automatically segmenting a medical image of a spine based on a pre-trained model so as to obtain different intervertebral disc segmentations; and biomechanical modelling under multiple motions for the different intervertebral disc segmentations so as to obtain dynamic properties of the intervertebral disc.
Owner:THE UNIVERSITY OF HONG KONG

Systems, devices, and methods for joint fusion

The present invention relates generally to implants and tools for the fixation or fusion of joints or bone segments. These tools include tissue dilators and protectors. Other tools include broaches used to shape bores in bone. The tools can also include a system for removing an implant from bone. Implants can include assemblies of one or more implant structures that make possible the achievement of diverse interventions involving the fusion and / or stabilization of lumbar and sacral vertebra in a non-invasive manner, with minimal incision, and without the necessitating the removing the intervertebral disc. Implants for fusing both sacroiliac joints of a patient include a long implant that extends across both sacroiliac joints.
Owner:SI BONE INC

Oriented degummed silk fiber reinforced polyvinyl alcohol hydrogel as well as preparation method and application thereof

The invention relates to the technical field of hydrogel, in particular to oriented degummed silk fiber reinforced polyvinyl alcohol hydrogel as well as a preparation method and application thereof.The hydrogel comprises degummed silk fiber and polyvinyl alcohol, has an anisotropic structure and can effectively enhance the fracture toughness and crack propagation resistance of the hydrogel. Through the assembly of the bionic fibrous ring structure, the multi-scale architecture of the natural intervertebral disc fibrous ring is simulated, the native fibrous ring structure is copied, and the mechanical microenvironment of the fibrous ring is simulated. The hydrogel and the artificial intervertebral disc have high toughness, long-term stability and biocompatibility, are particularly suitable for intervertebral disc repair, can stably bear biological load for a long time in intervertebral disc repair, and have relatively high application value.
Owner:ZHEJIANG UNIV OF TECH +2

Dual-channel complementary spine image segmentation method for segmenting vertebral body and intervertebral disc

A dual channel complementary spine image segmentation method for segmenting vertebral bodies and intervertebral discs is provided. [Solution] The method includes: obtaining a number of magnetic resonance images of the spine and corresponding label images, extracting and initially processing the slices to be segmented and the segmented slices; creating a residual neural network to extract detailed features, creating a spatial feature extraction device to extract related features, and creating a feature fusion module to fuse the detailed features and related features to obtain a segmentation feature map; outputting the segmentation results of only multiple categories through the network output layer, creating a dual-channel complemented spine image segmentation module; and obtaining an optimal dual-channel complemented spine image segmentation module through training, and obtaining the segmentation results of only multiple categories for the magnetic resonance image slices to be segmented.
Owner:DONGGUAN UNIV OF TECH

Intelligent intervertebral disc physiotherapy instrument with thermomagnetic function based on traditional Chinese medicine theory

The invention discloses an intelligent intervertebral disc physiotherapy instrument with a thermomagnetic function based on the theory of traditional Chinese medicine, and the instrument comprises a treatment bed, the outer surface of the front end of the treatment bed is provided with a control panel, the outer surface of the upper end of the treatment bed is fixedly connected with a base plate, and the outer surfaces of the two sides of the treatment bed are fixedly connected with a mounting frame. The inner surface of the upper end of the mounting frame is provided with a multidirectional adjustable positioning and supporting device used for improving the positioning convenience of intervertebral disc treatment, the multidirectional adjustable positioning and supporting device comprises a mounting seat, and the outer surface of the upper end of the mounting seat is fixedly connected with a fixing plate. According to the intelligent intervertebral disc physiotherapy instrument with the thermomagnetic function based on the theory of traditional Chinese medicine, the multidirectional adjustable positioning and supporting device is arranged, the structure is simple, the automation degree is high, automatic adjusting and positioning of the discomfort position of the intervertebral disc of a patient can be achieved, the use convenience of the device is improved, the accuracy of the treatment position is improved, and the practicability is high. The treatment effect is improved.
Owner:SUZHOU JIAKE BIOMEDICAL TECH CO LTD

Rat caudal vertebra intervertebral disc degeneration modeling device and method

The invention discloses a rat caudal vertebra intervertebral disc degeneration molding device which comprises an anesthesia box, a tail outlet hole is formed in the anesthesia box, a bearing table is arranged on the outer side of the anesthesia box, an arc-shaped locking plate is slidably installed on the bearing table, a containing groove is formed between the arc-shaped locking plate and the bearing table, and a sleeve is slidably installed on the arc-shaped locking plate in the circumferential direction; a puncture cylinder is in threaded connection with the interior of the sleeve, a graduated scale is axially arranged on the outer side wall of the puncture cylinder, a puncture needle is installed in the puncture cylinder and comprises a base and a needle head connected to the base, the base is installed in the puncture cylinder, the needle head sequentially penetrates through the puncture cylinder, the sleeve and the arc-shaped locking plate and then extends into the containing groove, and a bandage is arranged above the bearing table. An X-ray machine is arranged on the periphery of the bearing plate. The invention further discloses a rat caudal vertebra intervertebral disc degeneration modeling method using the rat caudal vertebra intervertebral disc degeneration modeling device. According to the rat caudal vertebra intervertebral disc degeneration modeling device and method, few tools are used, the process is simple, and application and popularization are convenient.
Owner:FIRST HOSPITAL AFFILIATED TO GENERAL HOSPITAL OF PLA

Bone fixation devices, systems, methods, and instruments

ActiveUS12290292B2Internal osteosythesisBone implantSpinal Disk ImplantIntervertebral spaces
An intervertebral implant may include a shaft having a proximal end, a distal end, a longitudinal axis, a minor diameter, and a helical thread disposed about the shaft along the longitudinal axis between the proximal end and the distal end of the shaft. The helical thread may include a major diameter and a concave undercut surface angled towards one of the proximal end and the distal end of the shaft. The intervertebral implant may be implanted within an intervertebral space between a superior vertebral body and an inferior vertebral body. A ratio of the major diameter to the minor diameter may be less than 1.50. The concave undercut surface may engage the superior vertebral body and the inferior vertebral body and may be shaped to resist at least one force transmitted between the superior vertebral body and the inferior vertebral body to stabilize the intervertebral space.
Owner:RTG SCIENTIFIC LLC

Devices and methods for transpedicular stabilization of the spine

According to some embodiments, a method of accessing an intervertebral space of a patient's spine in a minimally invasive manner compromises creating a passage from a posterior end of a pedicle of a vertebral member using a probe, advancing the probe through the pedicle and to a main body portion of the vertebral member, advancing the probe through a superior endplate of the vertebral member and into the intervertebral space and enlarging the passage using at least one tap to create an enlarged passage from a posterior of the pedicle to the intervertebral space. In some embodiments, the enlarged passage traverses at least three cortical layers of the vertebral member.
Owner:RAED M ALI M D

Artificial lumbar disc

The present disclosure relates to an artificial lumbar disc and provides a lateral approach artificial disc that is inserted laterally rather than anteriorly of the spine, thereby preventing damage to blood vessels or other organs that may occur when an anterior access artificial disc is inserted from the front, shortening the surgical time, preventing dislodgment of the artificial disc, and improving the surgical prognosis. The artificial disc is inserted between two adjacent vertebrae and includes an upper plate contacting an upper vertebra, a lower plate contacting a lower vertebra, and an inserter inserted between the upper plate and the lower plate to allow the upper plate to rotate by a set angle with respect to the lower plate, and an upper wing portion and a lower wing portion are formed on the upper plate and the lower plate.
Owner:HUB BIOTECH CO LTD

Interbody cage device and method for performing spinal surgical procedures

The present invention provides for improved interbody cage devices using surgical methods for delivering such cage into the disc space. The present invention has at least one advantage of providing practical and advantageous methods for accessing the spinal disc space to insert and deploy interbody cage devices in various manners that overcome the disadvantages of posterior, trans-sacro-iliac, anterior, oblique and lateral approaches thereto and minimize surgical trauma to the patient. Thus, the present invention provides for the unmet need for improved interbody cage devices which may be inserted to a disc space for patients exhibiting a wide range of anatomies.
Owner:NOVAPPROACH SPINE LLC

Multi-portal surgical systems

A multi-portal method for treating a subject's spine includes distracting adjacent vertebrae using a distraction instrument positioned at a first entrance along the subject to enlarge an intervertebral space between the adjacent vertebrae. An interbody fusion implant can be delivered into the enlarged intervertebral space. The interbody fusion implant can be positioned directly between vertebral bodies of the adjacent vertebrae while endoscopically viewing the interbody fusion implant using an endoscopic instrument. The patient's spine can be visualized using endoscopic techniques to view, for example, the spine, tissue, instruments and implants before, during, and after implantation, or the like. The visualization can help a physician throughout the surgical procedure to improve patient outcome.
Owner:AMPLIFY SURGICAL INC

Intervertebral disc repair material based on intervertebral disc degeneration staged treatment strategy as well as preparation method and application of intervertebral disc repair material

The invention belongs to the technical field of biomedical materials, and discloses an intervertebral disc repair material based on an intervertebral disc degeneration staged treatment strategy as well as a preparation method and application of the intervertebral disc repair material. The intervertebral disc repair material comprises a sandwich-structure dual-electroactive stent and composite hydrogel attached to the dual-electroactive stent, the double-electroactive stent with the sandwich structure comprises a conductive porous stent with a conductive through pore channel structure and piezoelectric fiber films positioned on the upper side and the lower side of the conductive porous stent; the composite hydrogel comprises hydrogel and antioxidant nano enzyme uniformly dispersed in the hydrogel; the antioxidant nano-enzyme is a core-shell structure nano-particle with Co-Ni bimetallic oxide as a core and polydopamine as a shell. The degeneration early intervertebral disc is repaired through the antioxidant and anti-inflammatory nano-enzyme, the defective intervertebral disc after resection is repaired through the double electroactive scaffolds, and the electroactive scaffold enhanced composite hydrogel can replace the degeneration later intervertebral disc, so that corresponding treatment is achieved for different stages of intervertebral disc degeneration.
Owner:WEST CHINA HOSPITAL SICHUAN UNIV

Traction bed adjusting method, device and equipment and storage medium

The invention relates to a traction bed adjusting method and device, equipment and a storage medium. According to the main technical scheme, the method comprises the following steps: acquiring a skin pain signal of a to-be-dragged part, a spine angle and a measurement distance of a skin electrical activity sensor, and judging whether a traction force currently generated by a traction bed on the to-be-dragged part causes pain or not according to the skin pain signal; when the traction force of the to-be-dragged part does not cause pain, the traction bed continues to be adjusted according to the spine angle, the measurement distance of the skin electrical activity sensor and preset intervertebral disc data, the pain feeling of a patient can be objectively evaluated, and it is guaranteed that the traction effect of the traction equipment is optimal.
Owner:XUANWU HOSPITAL OF CAPITAL UNIV OF MEDICAL SCI

Systems and methods for electrical properties tomography

Methods and systems for electrical properties tomography imaging are presented. Electrical properties such as conductivity and permittivity of intervertebral discs are calculated with improved accuracy and displayed for assessment of clinical personnel.
Owner:KONINKLIJKE PHILIPS NV

Application of thyroid hormone T3 in preparation of medicine for delaying or treating intervertebral disc degeneration

The invention relates to application of thyroid hormone T3 in preparation of a medicine for delaying or treating intervertebral disc degeneration, and the thyroid hormone T3 can inhibit glycolysis capability of degeneration nucleus pulposus cells and reduce intervertebral disc lactic acid accumulation, so that nucleus pulposus cell senescence and apoptosis are relieved, and intervertebral disc degeneration is delayed or treated. Compared with the prior art, the technology for delaying or treating intervertebral disc degeneration by applying the thyroid hormone T3 provides new application of the thyroid hormone T3, the application value of the thyroid hormone T3 is greatly improved, the application range of the thyroid hormone T3 is expanded, the new field of application of the thyroid hormone T3 is expanded, and the thyroid hormone T3 has wide application prospects and commercial value.
Owner:AFFILIATED HUSN HOSPITAL OF FUDAN UNIV

Neurosurgical minimally invasive surgery-oriented continuum robot

The invention relates to a continuum robot for neurosurgery minimally invasive surgery, which comprises a reaming assembly comprising a first reaming disc, a second reaming disc located behind the first reaming disc, a plurality of first tendons used for driving the first reaming disc, and a plurality of second tendons used for driving the second reaming disc; the supporting assembly is used for supporting a subsequent space after the first broaching disc and the second broaching disc broach in place and comprises a plurality of groups of first intervertebral discs and a plurality of groups of second intervertebral discs which are the same as the first intervertebral discs in structure and are arranged in the opposite direction, and the first intervertebral discs and the second intervertebral discs are arranged on the first tendon and the second tendon in a staggered and penetrating mode in the front-back direction; the driving assembly is used for synchronously driving the first intervertebral disc or the second intervertebral disc to unlock or lock the first tendon or the second tendon, so that the first intervertebral disc or the second intervertebral disc is alternately fed along the first tendon and the second tendon. The continuous robot has compact space design and FTL characteristics, and wounds and infringement to the human body can be reduced.
Owner:WUHAN UNIV

Self-healing bionic intervertebral disc capable of improving service stability and nucleus pulposus preparation method thereof

The invention relates to a self-healing bionic intervertebral disc capable of improving service stability and a nucleus pulposus preparation method of the self-healing bionic intervertebral disc, and belongs to the field of bionic implant prostheses. The self-healing bionic intervertebral disc capable of improving the service stability is composed of an upper end plate, a bionic fibrous ring layer, a lower end plate and a bionic nucleus pulposus, the bionic nucleus pulposus adopts dynamic cross-linked hydrogel to simulate the viscoelasticity and moisture regulation function of a natural nucleus pulposus, and the buffering and self-healing characteristics of the bionic intervertebral disc are achieved; the bionic fiber ring layer achieves gradient mechanical properties through directionally-arranged composite materials, and three-dimensional physiological movement of the artificial intervertebral disc close to the lumbar vertebra of a human body is achieved. The bionic intervertebral disc provided by the invention is matched with viscoelasticity of a natural intervertebral disc, recovers natural matching with three-dimensional physiological movement of a human spine, can buffer dynamic load and maintain intervertebral height, can perform micro-injury self-repair through dynamic crosslinking of chemical bonds in bionic nucleus pulposus, and has a good application prospect. And the kinematic mechanical stability of long-term service in a human body is realized.
Owner:JILIN UNIVERSITY +1