454 results about "Intervertebral disc" patented technology

The invention discloses an in-vitro bionic mechanical testing system and method for spinal skeletal muscles, and particularly relates to the field of mechanical testing, and the system comprises a bionic construction module, a finite element modeling module, a multi-axis mechanical loading module, an iterative calculation module and a correction module; through modular design, the system comprises a vertebral body unit, an intervertebral disc simulation assembly and a skeletal muscle simulation unit, each assembly is customized according to anatomical features of a human body, a finite element modeling module is utilized to generate a three-dimensional model, a multi-directional mechanical load is applied, and response data is collected; experimental data are input into the finite element model for iterative calculation, so that stress distribution, a strain field and kinematic deviation are compared; if the error exceeds a preset threshold value, the model parameters and the physical parameters are corrected until the experiment and simulation results converge; and finally, based on the optimized finite element model, predicting a failure mechanism of the spinal skeletal muscle under a complex load, and evaluating the risks of fracture, hairline fracture, nucleus pulposus protrusion and muscle strain.

The embodiment of the invention provides a spine image recognition method and related equipment. The spine image recognition comprises the following steps: acquiring a spine image to be detected, and preprocessing the spine image to be detected to obtain a target spine image; the target spine image is input into a key point recognition model, position information output by the key point recognition model for each section of vertebral body in the target spine image is obtained, and the position information is marked on the target spine image and at least comprises positioning frame information, a vertebral body name and angular point coordinates; the key point identification model comprises a CBAM module; correcting and adjusting the position information to obtain corrected position information; and performing intervertebral disc positioning and vertebra identification according to the corrected position information. According to the technical scheme, the improved key point recognition model is adopted, the positioning frame, the cone name and the angular point coordinates are directly output without depending on a segmentation model, the process is simplified, and the detection speed and robustness are improved.

A discectomy method entails removing at least a portion of a spinal lamina to form an access path in a patient. A surgical instrument is inserted along the path and a distal end of the instrument is placed in operative contact with herniated or bulging disc material of a spinal disc. The instrument is operated to remove the herniated or bulging disc material, to thereby space a remaining portion of the spinal disc from spinal nerves. A tip of an ultrasonic surgical probe is then placed into contact with an outer surface of the remaining portion of the spinal disc, and an ultrasonic mechanical standing wave generated in the probe while maintaining the operative tip in contact with the outer surface to harden the wall surface and thereby reduce chances of disc herniation at the outer surface.

The invention specifically discloses an automatic generation method for a cervical vertebra disease rehabilitation prescription, and the method comprises the steps: constructing a cervical vertebra image feature automatic measurement system based on computer vision and deep learning, so as to monitor the training motion quality of a patient in real time, and obtaining the kinematics parameters of rehabilitation exercise training; acquiring a medical image and clinical data of a patient, and standardizing the medical image to construct a standard space of a multi-modal medical image; performing automatic segmentation and anatomical structure calibration on a vertebral body-intervertebral disc based on the standard space to obtain fusion image features; and constructing a multi-modal hierarchical decision model fusing the image features, the kinematics parameters and the clinical data to carry out quantitative analysis on pathological feature parameters, and outputting a standardized illness state assessment result conforming to international clinical guidelines. The dynamic optimization of the treatment scheme can be realized through a feedback mechanism, and the treatment effect is improved.

The present technology includes patient-specific spinal fusion devices, which may include an interbody implant that is designed to be positioned within a disc space between two vertebral bodies and one or more fixation elements that can anchor the interbody implant to the vertebral bodies. The fusion devices include one or more retention mechanisms for retaining the fixation elements within corresponding lumens or bore holes extending through the interbody implant. Methods for designing and manufacturing patient-specific spinal fusion devices are also described herein.

An access device for accessing an intervertebral disc having an outer shield comprising an access shield with a larger diameter (˜16-30 mm) that reaches from the skin down to the facet line, with an inner shield having a second smaller diameter (˜5-12 mm) extending past the access shield and reaches down to the disc level. This combines the benefits of the direct visual microsurgical / mini open approaches and the percutaneous, “ultra-MIS” techniques.

The invention provides a device for constructing an intervertebral disc degeneration model by using mouse simulation, and belongs to the technical field of medical research. Comprising a mounting base plate, a supporting rod is connected to the middle of the top of the mounting base plate, a top seat is fixedly connected to the top of the supporting rod, and a ring seat is fixedly connected to the inner side of the top seat. The body clamping mechanism can accurately clamp an animal body, is matched with an electric push rod to realize bending or unfolding of the body, and is matched with the limb positioning mechanism to improve the experiment suitability and assist in simulating the pathological process of human intervertebral disc degeneration, the limb positioning mechanism fixes the limbs of the animal through antiskid plates, and the device can adapt to animals with different sizes and is high in practicability. The rotating shaft design avoids animal limb fracture, the angle adjusting assembly and the arc-shaped displacement assembly enable the animal limbs to flexibly swing and move up and down, the convenience and the adjusting adaptation performance of the device are improved, and more accurate data and reliable experiment conditions are provided for lumbar vertebra pathological research on the whole.

The invention discloses a lumbar disc herniation identification method and system based on a CT image, and the method comprises the steps: carrying out the multi-dimensional projection slice processing of input CT image data, and obtaining a multi-dimensional feature projection slice image data set; according to the multi-dimensional feature projection slice image data set, constructing an adaptive expansion bounding box model, and automatically generating a segmentation boundary of the lumbar intervertebral disc by using a nonlinear constraint iteration function to obtain a lumbar intervertebral disc three-dimensional voxel model of a target segmentation area; for the lumbar intervertebral disc three-dimensional voxel model, outputting a high-dimensional lumbar vertebra texture feature vector by using a fiber enhanced tensor network; and according to the high-dimensional lumbar vertebra texture feature vector, combining anatomical appearance features of the lumbar intervertebral disc at different positions in the multi-dimensional projection slice to construct a multi-dimensional fusion label classification model so as to output a normal or protruding identification result of the lumbar intervertebral disc. According to the embodiment of the invention, modern image processing and deep learning technologies can be combined, and the recognition rate and accuracy of lumbar disc herniation can be effectively improved.

The present invention relates generally to implants and tools for the fixation or fusion of joints or bone segments. These tools include tissue dilators and protectors. Other tools include broaches used to shape bores in bone. The tools can also include a system for removing an implant from bone. Implants can include assemblies of one or more implant structures that make possible the achievement of diverse interventions involving the fusion and / or stabilization of lumbar and sacral vertebra in a non-invasive manner, with minimal incision, and without the necessitating the removing the intervertebral disc. Implants for fusing both sacroiliac joints of a patient include a long implant that extends across both sacroiliac joints.

The invention relates to the technical field of hydrogel, in particular to oriented degummed silk fiber reinforced polyvinyl alcohol hydrogel as well as a preparation method and application thereof.The hydrogel comprises degummed silk fiber and polyvinyl alcohol, has an anisotropic structure and can effectively enhance the fracture toughness and crack propagation resistance of the hydrogel. Through the assembly of the bionic fibrous ring structure, the multi-scale architecture of the natural intervertebral disc fibrous ring is simulated, the native fibrous ring structure is copied, and the mechanical microenvironment of the fibrous ring is simulated. The hydrogel and the artificial intervertebral disc have high toughness, long-term stability and biocompatibility, are particularly suitable for intervertebral disc repair, can stably bear biological load for a long time in intervertebral disc repair, and have relatively high application value.

Various embodiments of cervical plates for treating the spine are provided. The cervical plates include an access surface and a bone facing surface. The cervical plate further includes at least one hole between the access surface and the bone facing surface. The hole includes a trajectory surface that guides an anchor into a corner or edge of a vertebral body, wherein a portion of the hole extends into the disc space region. In some embodiments, the cervical plate includes a ledge to support high angle screw insertion. In some embodiments, an interbody implant is provided. The cervical plate and the interbody spacer can have a corresponding curvature.

The invention discloses an intelligent intervertebral disc physiotherapy instrument with a thermomagnetic function based on the theory of traditional Chinese medicine, and the instrument comprises a treatment bed, the outer surface of the front end of the treatment bed is provided with a control panel, the outer surface of the upper end of the treatment bed is fixedly connected with a base plate, and the outer surfaces of the two sides of the treatment bed are fixedly connected with a mounting frame. The inner surface of the upper end of the mounting frame is provided with a multidirectional adjustable positioning and supporting device used for improving the positioning convenience of intervertebral disc treatment, the multidirectional adjustable positioning and supporting device comprises a mounting seat, and the outer surface of the upper end of the mounting seat is fixedly connected with a fixing plate. According to the intelligent intervertebral disc physiotherapy instrument with the thermomagnetic function based on the theory of traditional Chinese medicine, the multidirectional adjustable positioning and supporting device is arranged, the structure is simple, the automation degree is high, automatic adjusting and positioning of the discomfort position of the intervertebral disc of a patient can be achieved, the use convenience of the device is improved, the accuracy of the treatment position is improved, and the practicability is high. The treatment effect is improved.

The invention discloses a rat caudal vertebra intervertebral disc degeneration molding device which comprises an anesthesia box, a tail outlet hole is formed in the anesthesia box, a bearing table is arranged on the outer side of the anesthesia box, an arc-shaped locking plate is slidably installed on the bearing table, a containing groove is formed between the arc-shaped locking plate and the bearing table, and a sleeve is slidably installed on the arc-shaped locking plate in the circumferential direction; a puncture cylinder is in threaded connection with the interior of the sleeve, a graduated scale is axially arranged on the outer side wall of the puncture cylinder, a puncture needle is installed in the puncture cylinder and comprises a base and a needle head connected to the base, the base is installed in the puncture cylinder, the needle head sequentially penetrates through the puncture cylinder, the sleeve and the arc-shaped locking plate and then extends into the containing groove, and a bandage is arranged above the bearing table. An X-ray machine is arranged on the periphery of the bearing plate. The invention further discloses a rat caudal vertebra intervertebral disc degeneration modeling method using the rat caudal vertebra intervertebral disc degeneration modeling device. According to the rat caudal vertebra intervertebral disc degeneration modeling device and method, few tools are used, the process is simple, and application and popularization are convenient.

An intervertebral implant may include a shaft having a proximal end, a distal end, a longitudinal axis, a minor diameter, and a helical thread disposed about the shaft along the longitudinal axis between the proximal end and the distal end of the shaft. The helical thread may include a major diameter and a concave undercut surface angled towards one of the proximal end and the distal end of the shaft. The intervertebral implant may be implanted within an intervertebral space between a superior vertebral body and an inferior vertebral body. A ratio of the major diameter to the minor diameter may be less than 1.50. The concave undercut surface may engage the superior vertebral body and the inferior vertebral body and may be shaped to resist at least one force transmitted between the superior vertebral body and the inferior vertebral body to stabilize the intervertebral space.

According to some embodiments, a method of accessing an intervertebral space of a patient's spine in a minimally invasive manner compromises creating a passage from a posterior end of a pedicle of a vertebral member using a probe, advancing the probe through the pedicle and to a main body portion of the vertebral member, advancing the probe through a superior endplate of the vertebral member and into the intervertebral space and enlarging the passage using at least one tap to create an enlarged passage from a posterior of the pedicle to the intervertebral space. In some embodiments, the enlarged passage traverses at least three cortical layers of the vertebral member.

The present disclosure relates to an artificial lumbar disc and provides a lateral approach artificial disc that is inserted laterally rather than anteriorly of the spine, thereby preventing damage to blood vessels or other organs that may occur when an anterior access artificial disc is inserted from the front, shortening the surgical time, preventing dislodgment of the artificial disc, and improving the surgical prognosis. The artificial disc is inserted between two adjacent vertebrae and includes an upper plate contacting an upper vertebra, a lower plate contacting a lower vertebra, and an inserter inserted between the upper plate and the lower plate to allow the upper plate to rotate by a set angle with respect to the lower plate, and an upper wing portion and a lower wing portion are formed on the upper plate and the lower plate.

Methods and systems for electrical properties tomography imaging are presented. Electrical properties such as conductivity and permittivity of intervertebral discs are calculated with improved accuracy and displayed for assessment of clinical personnel.

The invention relates to a continuum robot for neurosurgery minimally invasive surgery, which comprises a reaming assembly comprising a first reaming disc, a second reaming disc located behind the first reaming disc, a plurality of first tendons used for driving the first reaming disc, and a plurality of second tendons used for driving the second reaming disc; the supporting assembly is used for supporting a subsequent space after the first broaching disc and the second broaching disc broach in place and comprises a plurality of groups of first intervertebral discs and a plurality of groups of second intervertebral discs which are the same as the first intervertebral discs in structure and are arranged in the opposite direction, and the first intervertebral discs and the second intervertebral discs are arranged on the first tendon and the second tendon in a staggered and penetrating mode in the front-back direction; the driving assembly is used for synchronously driving the first intervertebral disc or the second intervertebral disc to unlock or lock the first tendon or the second tendon, so that the first intervertebral disc or the second intervertebral disc is alternately fed along the first tendon and the second tendon. The continuous robot has compact space design and FTL characteristics, and wounds and infringement to the human body can be reduced.

The invention relates to a self-healing bionic intervertebral disc capable of improving service stability and a nucleus pulposus preparation method of the self-healing bionic intervertebral disc, and belongs to the field of bionic implant prostheses. The self-healing bionic intervertebral disc capable of improving the service stability is composed of an upper end plate, a bionic fibrous ring layer, a lower end plate and a bionic nucleus pulposus, the bionic nucleus pulposus adopts dynamic cross-linked hydrogel to simulate the viscoelasticity and moisture regulation function of a natural nucleus pulposus, and the buffering and self-healing characteristics of the bionic intervertebral disc are achieved; the bionic fiber ring layer achieves gradient mechanical properties through directionally-arranged composite materials, and three-dimensional physiological movement of the artificial intervertebral disc close to the lumbar vertebra of a human body is achieved. The bionic intervertebral disc provided by the invention is matched with viscoelasticity of a natural intervertebral disc, recovers natural matching with three-dimensional physiological movement of a human spine, can buffer dynamic load and maintain intervertebral height, can perform micro-injury self-repair through dynamic crosslinking of chemical bonds in bionic nucleus pulposus, and has a good application prospect. And the kinematic mechanical stability of long-term service in a human body is realized.

Disclosed methods, devices, and systems are suitable for performing minimally-invasive procedures for accessing the intervertebral space along an oblique pathway with an insertion instrument that holds a disc implant, and reorienting the angular relationship between instrument and implant while the implant is inside the body (for example at or within the disc space).

The invention provides a multi-spine structure segmentation method and system based on a CT image, and belongs to the technical field of medical image segmentation. A to-be-segmented CT image and a plurality of historical CT images are acquired and preprocessed; inputting the historical CT image into the deep neural network for training; inputting a CT image to be segmented into the trained deep neural network, wherein the deep neural network is composed of a bone tissue segmentation network and a soft tissue enhancement network; extracting centrum features of the CT image by using a bone tissue segmentation network to obtain a centrum segmentation image; segmenting a soft tissue structure of the CT image by using a soft tissue enhanced network to obtain an intervertebral disc segmentation image and a nerve segmentation image; and integrating the vertebral body segmentation image, the intervertebral disc segmentation image and the nerve segmentation image to obtain a complete lumbar vertebra structure segmentation image. According to the method, the vertebral body, the intervertebral disc and the nerve in the spine CT image can be efficiently and automatically segmented at the same time.

An interbody implant can comprise a cage and a porous structure. The cage can comprise an anterior segment, a medial segment, a posterior segment and a lateral segment contiguously connected to each other to define an interior space. The porous structure can be located in the interior space and can be bounded by the cage. The porous structure can comprise opposed superior and inferior surfaces exposed through the cage, an internal cavity located in an interior of the porous structure, and a plurality of ports connecting the internal cavity to the superior and inferior surfaces. A superior-inferior stiffness of the interbody implant can be defined by the porous structure. The porous structure can be compressed within a patient by movement of the spine to biologically stimulate bone growth in vertebrae adjacent the interbody implant. The implant can be configured for lateral, anterior and posterior insertion at different spine levels.

The invention discloses a patient-specific finite element model-based vertebroplasty optimization method and a related device. The method comprises the following steps of: constructing a patient-specific three-dimensional spine model according to a vertebral bone structure and a vertebral soft tissue structure; discretizing the patient-specific three-dimensional spine model into tetrahedral finite element grids, endowing each finite element unit with bone material attributes according to pixel values of CT scanning images, and endowing intervertebral disc and ligament soft tissue structures with soft tissue material attributes; determining an optimal bone cement injection path and an optimal bone cement injection amount of the tetrahedral finite element mesh; and simulating the vertebroplasty in the tetrahedral finite element mesh, predicting the stress distribution of the vertebrae, the rigidity of the vertebrae and the stress change of the adjacent vertebrae after the operation, and presenting the simulation result of the simulated vertebroplasty in a three-dimensional visual form. According to the method, personalized optimization and prediction of preoperative simulation of the vertebroplasty are realized by constructing the patient-specific finite element model, and an efficient auxiliary reference operation scheme is provided for an operator.

The invention relates to application of mitochondrial E3 ligase MAPL and an inhibitor of the mitochondrial E3 ligase MAPL in preparation of a medicine for treating intervertebral disc degeneration. MAPL increases mitochondrial translocation of Drp1 by promoting SUMOylation modification of Drp1 to cause abnormal mitochondrial division of nucleus pulposus cells to play a pathophysiological role, and in-vivo inhibition of MAPL can significantly reverse the degeneration phenotype of intervertebral disc. Compared with the prior art, the invention focuses on the SUMOylation modification effect of MAPL on Drp1, and aims to reveal the molecular mechanism of the MAPL for influencing the IVDD process by regulating mitochondrial division, thereby providing an innovative theoretical basis for developing a precise targeted therapy strategy.

The present invention discloses a method for preparing a micro bionic intervertebral disc scaffold by using near-field direct writing 3D printing technology. The present invention uses near-field direct writing 3D printing technology to print fiber ring laminated scaffolds with a reticular laminated intersecting structure of various specifications, arranges the fiber ring laminated scaffolds in the order of increasing pore size, heats the fiber ring laminated scaffolds, and manually curls the fiber ring laminated scaffolds at an angle of 45° obliquely to imitate the structure of the rat fiber ring, obtaining a simulated fiber ring laminated scaffold with a gradient change in pore size from inside to outside; methyl acrylated gelatin GelMA is perfused into the center of the fiber ring laminated scaffold as the nucleus pulposus to obtain a highly bionic intervertebral disc scaffold. The intervertebral disc scaffold prepared by the present invention has the characteristics of small size, ultra-high precision, high bionics, and good repair effect, and has been successfully used for micro spinal repair of small vertebrates, and is expected to be applied to intervertebral disc replacement and repair of vertebrates.

The disclosure provides a method of treating intervertebral disc hernia, the method including applying low intensity laser radiation to the soft tissues of the patient, surrounding the hernia. The disclosure also provides a radiating system for implementing the method and use of the radiating system treating intervertebral disc hernia.

The invention involves a retraction distraction blade system suitable for use with retractor and distractor tools for the implantation of intervertebral implants into the spine area of an animal, particularly humans. The retractor distractor blade includes structures for attaching the blade to a retractor or distractor tool to provide visual access to a surgical site. The blade is provided with a threaded member connected to a flexible lasso for securement around a portion of a pedicle screw or bone screw. Once the lasso is secured to the pedicle screw, the retractor is prevented from moving out of the surgical site. Operation of the distractor or retractor tool can then be utilized to provide distraction to the spinal vertebrae for implant insertion or spinal alignment. Once the procedure is sufficiently complete, the lasso can be removed from the pedicle screws.

The present invention relates to a method for determining the disc incision depth of posterior lumbar interbody fusion, comprising the following steps: (1) Selecting patients with lumbar degenerative diseases who have undergone X-ray examination and plain CT scan of lumbar intervertebral discs as samples; (2) Removing unqualified samples; (3) Taking anteroposterior and lateral X-rays of the lumbar spine with the patient standing, and performing tomographic scanning with the patient lying flat; (4) Measuring the lengths of the lower edges of the L3 (the third lumbar vertebra), L4 (the fourth lumbar vertebra), and L5 (the fifth lumbar vertebra) vertebral bodies in the X-ray films as the X-ray depths of the L3 / 4, L4 / 5, and L5 / S1 intervertebral spaces; (5) Performing statistical analysis using SPSS 18.0 software and making a table of the analysis results; (6) Obtaining the warning value of the disc incision depth based on the data results. This method provides the warning value of the insertion depth of the nucleus pulposus forceps for medical staff performing posterior lumbar interbody fusion, improving the safety and success rate of interbody fusion.

1. Name of the product in this design: Percutaneous endoscopic discectomy. 2. Purpose of this design: This design is used for observation, diagnosis and adjunctive treatment of spinal parts such as intervertebral foramina and intervertebral discs. 3. The key design feature of this product is its shape. 4. The image or photograph that best illustrates the design's key points: a 3D model.

The invention relates to the technical field of LDH image processing, and provides an image auxiliary recognition method and system for LDH. The method comprises the steps that a lumbar vertebra image and a posture image of a patient are acquired, a human body posture in the posture image is recognized through an artificial intelligence model, the stress condition of the lumbar vertebra under the posture is predicted, stress of all vertebrae in the lumbar vertebra image is positioned, and a positioning result is obtained; according to the method, the stress condition of each intervertebral disc is obtained, and the outline of the intervertebral disc is corrected based on the stress condition of the intervertebral disc, so that the outline change caused by the posture when the patient shoots the image in the intervertebral disc image can be eliminated, a doctor is assisted to identify and analyze the image, and the misjudgment risk is reduced.