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A two-component fluid dispenser which can accurately mix two liquids of varying viscosity and then precisely deliver the mixture formed in discrete amounts. The mixture of the two components is delivered from a single delivery tube in a manner such that none of the mixture remains within the delivery tube at the completion of each mixing and delivery cycle. In one form of the apparatus, the single delivery tube of the apparatus is operably coupled with conventional hypodermic syringes of various sizes so that different fluids can be mixed in different ratios.

A method for connecting a graft vessel to a target vessel, each vessel having a wall surrounding a lumen, may include providing a connector holder, associating an end of the graft vessel with the connector holder, positioning the connector holder outside of the lumen of the target vessel, outside the lumen of the graft vessel, and in proximity to the outer surface of the wall of the target vessel, and actuating the connector holder to secure the end of the graft vessel to the side of the target vessel.

The present invention provides an expandable intervertebral implant that is selectively disposed in the intervertebral space and deployed, thereby in-situ distracting, realigning, and / or stabilizing or fusing a portion of the spine of a patient in the treatment of injury, disease, and / or degenerative condition. The expandable intervertebral implant includes a superior member and an inferior member, each of which has a partially or substantially wedge or prismatic shape and a partially or substantially convex or other-shaped surface that is suitable for engaging the substantially concave surfaces of the associated bony superior and inferior intervertebral endplates. Once disposed in the intervertebral space, the expandable intervertebral implant is actuated and deployed, with the superior member and the inferior member moving apart from one another, seating against the associated intervertebral endplates, and distracting, realigning, and / or stabilizing them to a desired degree. The external surface of each of the superior member and the inferior member is provided with a plurality of ridges or other friction structures, providing purchase with the associated intervertebral endplates.

In various exemplary embodiments, the present invention provides a plurality of novel interspinous distraction devices and associated methods of insertion. The interspinous distraction devices of the present invention are designed and configured to effectively treat such conditions as lumbar spinal stenosis and degenerative disc disease. Advantageously, the interspinous distraction devices of the present invention may be inserted through conventional open procedures, typically requiring a relatively large incision and a general anesthetic, or through novel minimally-invasive procedures, typically requiring only a local anesthetic. These novel minimally-invasive procedures and related enabling devices are also disclosed and described herein.

The present invention provides an expandable intervertebral implant, including: a superior member configured to engage a superior intervertebral body; an inferior member configured to engage an inferior intervertebral body; and an expansion mechanism disposed between the superior member and the inferior member configured to selectively adjust a separation of the superior member from the inferior member; wherein the expansion mechanism includes a proximal wedge structure and a distal wedge structure that are relatively translated between the superior member and the inferior member, wherein the proximal wedge structure and the distal wedge structure are each coupled to the superior member and the inferior member by a plurality of aligned and / or staggered (i.e. nested) track structures and rail structures.

The present invention provides an expandable intervertebral implant, including: a superior member configured to engage a superior intervertebral body; an inferior member configured to engage an inferior intervertebral body; and an expansion mechanism disposed between the superior member and the inferior member configured to selectively adjust a separation of the superior member from the inferior member; wherein the expansion mechanism includes a proximal wedge structure and a distal wedge structure that are relatively translated between the superior member and the inferior member, wherein the proximal wedge structure and the distal wedge structure are each coupled to the superior member and the inferior member by a plurality of aligned and / or staggered (i.e. nested) track structures and rail structures; and wherein a load-bearing portion of a bottom surface of the superior member is configured to mate vertically with a load-bearing portion of a top surface of the inferior member when the expansion mechanism is undeployed via conformal protruding and recessed features.

An endoscopic staple and related stapling device that can be used in conjunction with flexible or rigid endoscopy. The staple can also be used for other surgical procedures. The invention relates to performing a stapling operation on internal body tissues as part of a surgical procedure, diagnostic procedure or therapeutic procedure. This invention includes a surgical staple, an associated staple holder, and an associated staple delivery and deployment device. The staple holder and delivery system have a design iteration whereby the holder can be reloaded with additional staples to be used on the same patient. There is another design iteration whereby the staple holder and stapler are reusable after appropriate cleaning and sterilization.

An endoscopic staple and related stapling device that can be used in conjunction with flexible or rigid endoscopy. The staple can also be used for other surgical procedures. The invention relates to performing a stapling operation on internal body tissues as part of a surgical procedure, diagnostic procedure or therapeutic procedure. This invention includes a surgical staple, an associated staple holder, and an associated staple delivery and deployment device. The staple holder and delivery system have a design iteration whereby the holder can be reloaded with additional staples to be used on the same patient. There is another design iteration whereby the staple holder and stapler are reusable after appropriate cleaning and sterilization.

An intervertebral prosthesis, in particular for the cervical spine, includes a first cover plate to be connected to a first vertebral body, a second cover plate to be connected to the second vertebral body, and a prosthesis core which forms an articulation with the second cover plate. The prosthesis core is held by a seat of the first cover plate which is designed as a guide device. The core can be pushed into the guide device from the ventral side in the anterior-posterior (AP) direction relative to the first cover plate. A limit-stop plate is provided on the ventral edge of the first cover plate. This limit-stop plate is displaceable in a slide guide between a locking position and a nonlocking position.

The invention relates to a device forming an endoluminal endoprosthesis. The device comprises at least a first segment, and upstream from said segment, at a predetermined distance therefrom, it comprises a "fixing" upstream segment made of a biocompatible material so as to be deployable from a closed or non-deployed position for insertion purposes to a deployed working position, the deployed working position being designed to be located in a healthy zone of blood vessel and being separated from the first segment by a predetermined distance defined by links of predetermined length. The invention makes it easy to recatheterize a blood vessel such as the abdominal aorta suffering from an aneurysm.

A lighting fixture comprises a mounting assembly and two rails. At least one of the rails is slidable relative to the mounting assembly. The rails are each extruded, and have profiles which are substantially similar to each other. Each rail has a male component which fits within a female component of the other. Also, a fixture comprising a mounting assembly comprising an opening through which a light engine housing can be inserted, and (1) a spring clip and / or (2) a clip engagement structure. Also, a fixture comprising a mounting assembly, a first set of rails, and a supplemental rail. The supplemental rail is slidable relative to the light emitting element mounting assembly. Also, a fixture comprising a mounting assembly, a set of rails, and an engagement element having a first portion being in contact with a first rail and a second portion in contact with the second rail.

The present invention provides an expandable intervertebral implant that is selectively disposed in the intervertebral space and deployed, thereby in-situ distracting, realigning, and / or stabilizing or fusing a portion of the spine of a patient in the treatment of injury, disease, and / or degenerative condition. The expandable intervertebral implant includes a superior member and an inferior member, each of which has a partially or substantially wedge or prismatic shape and a partially or substantially convex or other-shaped surface that is suitable for engaging the substantially concave surfaces of the associated bony superior and inferior intervertebral endplates. Once disposed in the intervertebral space, the expandable intervertebral implant is actuated and deployed, with the superior member and the inferior member moving apart from one another, seating against the associated intervertebral endplates, and distracting, realigning, and / or stabilizing them to a desired degree. The external surface of each of the superior member and the inferior member is provided with a plurality of ridges or other friction structures, providing purchase with the associated intervertebral endplates.

A surgical punch prevents tissue debris associated with punching a hole in a patient's tissue, such as an aorta during an anastomosis procedure, from reentering the patient's bloodstream. The punch includes elements that move the debris away from the cutting site and then capture that debris inside the instrument. The punch also includes means for aligning the punch with the selected site and for atraumatically holding the tissue prior to cutting. Various means for moving the tissue debris and for trapping the tissue debris in the instrument are also disclosed.

The goggles of the invention utilize a substantially rigid frame with separate top and bottom individually rotatable elements, namely an upper browbar and a lower nosepiece, that firmly capture the lens from above and below. The lens is further secured to the frame by projections on each of the browbar and nosepiece which fit through apertures in the lens. At the top, a post which projects forwardly from the frame is received in the well of the browbar by snap-fit engagement. At the bottom, a prong on the rotatable nosepiece passes through a bottom aperture of the lens and is received in a recess of a bottom portion of the frame by snap-fit engagement. The apertures and cooperating projections are preferably located along the center of a one-piece lens. Thus, the rotatable browbar and nosepiece capture the lens top and bottom by edgewise compression and hold the lens front-to-back.

Described herein are suture passers for suturing tissue in a continuous manner by passing a suture attached to a suture shuttle through. A suture passer may include a first jaw, a second jaw, and a tissue perpetrator that is retractable and extendable from the first jaw. The tissue penetrator may have a suture shuttle engagement region, and the second jaw may include a shuttle dock. The suture shuttle may be transferred between the first and second jaws as the tissue penetrator is extended from the first jaw and engages the second jaw. In some variations of the tissue passer, one or both jaws are tissue penetrating. In some variations, the jaws open in parallel, allowing large tissue regions to be positioned between the jaws. Methods of using these devices are also described, as are systems and kits including these devices.

An end effector includes an anvil and a cartridge assembly having a plurality of surgical staples disposed in a cavity defined therein. The cartridge assembly may include a movable driver or sled configured to deploy the surgical staple from the cavity into tissue. The surgical staple may include a linear leg and an arcuate leg extending therefrom. The linear leg may include a protruding portion to provide pressure to tissue captured by the surgical staple. A three-dimensional and / or self-supporting surgical staple may interlock its two legs upon deployment thereof.

Provided is a bone joining device suitable for joining a first bone piece to a second bone piece. Also provided is a method of joining a first bone piece with a second bone piece in a living mammal. The method comprises inserting the above bone joining device between the first bone piece and the second bone piece.

Anchoring or docking devices configured to be positioned at a native valve of a human heart and to provide structural support for docking a prosthetic valve therein. The docking devices can have coiled structures that define an inner space in which the prosthetic valve can be held. The docking devices can have enlarged end regions with circular or non-circular shapes, for example, to facilitate implantation of the docking device or to better hold the docking device in position once deployed. The docking devices can be laser-cut tubes with locking wires to assist in better maintaining a shape of the docking device. The docking devices can include various features to promote friction, such as frictional cover layers. Such docking devices can have ends configured to more securely attach the cover layers to cores of the docking devices.

The present invention provides an expandable intervertebral implant, including: a superior member configured to engage a superior intervertebral body; an inferior member configured to engage an inferior intervertebral body; and an expansion mechanism disposed between the superior member and the inferior member configured to selectively adjust a separation of the superior member from the inferior member; wherein the expansion mechanism includes a proximal wedge structure and a distal wedge structure that are relatively translated between the superior member and the inferior member, wherein the proximal wedge structure and the distal wedge structure are each coupled to the superior member and the inferior member by a plurality of aligned and / or staggered (i.e. nested) track structures and rail structures; and wherein a load-bearing portion of a bottom surface of the superior member is configured to mate vertically with a load-bearing portion of a top surface of the inferior member when the expansion mechanism is undeployed via conformal protruding and recessed features.

A safety port needle assembly used to connect an IV line to an implanted port needle receiving port. The assembly includes an L-shaped port needle with an integrally attached horizontal leg member, a vertical leg member, an elongated, fixed main body and a pivotally attached needle arm. The horizontal leg member is longitudinally aligned and attached to the needle arm. The vertical leg member extends downward perpendicular to the longitudinal axis of the needle arm. A channel is formed in the main body that enables the needle arm to rest longitudinally against the main body. A bore is also formed in the main body so that the vertical leg member may extend downward through the main body. Formed near the distal end of the main body is a pair of laterally extended wings.

A needle guidance device for use with an ultrasound transducer is made up of a frame for housing the transducer, a needle guide unit which has a sleeve in line with an ultrasound beam and two arms which affix the frame to the needle guide unit.

The present disclosure is directed to a protective support device that includes a planar unitary elastomeric body having a central portion and at least two end segments extending from the central portion, each end segment having an opening formed therein, each opening structured to engage with opposing corners of a tablet computer.

A method of manufacturing an osteoinductive osteoimplant is provided which comprises the steps of: demineralizing part or all of at least one surface of a monolithic section of cortical bone to a depth of at least about 100 microns; and, configuring the monolithic section of cortical bone to provide an osteoimplant possessing an outer surface possessing at least one demineralized zone and a non-demineralized zone. An implant produced according to the above method demonstrates improved osteoinduction without producing any clinically significant reduction of strength in critical regions of the osteoimplant.

A liquid crystal display panel, in which a first substrate (1) and a second substrate (6) are opposed to each other with a predetermined gap provided therebetween, a liquid crystal layer (25) is sealed in the gap with a sealant (26), pixel portions are formed by electrodes (2, 7), the electrodes being provided on the first substrate (1) and on the second substrate (6) to oppose to each other via the liquid crystal layer (25), and lead electrodes (41) for applying electric signals to the electrodes (2, 7) forming the pixel portions are provided at least on the first substrate (1), wherein a thin film insulating layer (22) being an insulating covering member is provided to cover at least portions of the lead electrodes (41) outside the sealant (26) and overlap with a portion of the second substrate (6).