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15results about How to "Overcome problems" patented technology

Lamp strip assembly and motor vehicle

The invention provides a lamp strip assembly. The lamp strip assembly comprises a flexible circuit board; the plurality of light sources are electrically connected to the flexible circuit board and are arranged at intervals along the extension direction of the flexible circuit board; the optical structure comprises a first end, a second end, a light emitting part and a side part, the light emitting part and the side part extend from the first end to the second end in the extending direction, the side part is connected with the light emitting part, and the flexible circuit board and the light sources are located in the optical structure; the light emitting part is used for emitting light rays emitted by the plurality of light sources, and an opening is formed in the side part; and an electrical connection portion extending from an interior of the optical structure to an exterior of the optical structure through the opening.
Owner:VALEO VISION SA

Sorafenib or donafenib oral preparation with low dose and high drug exposure, and application thereof

InactiveEP4331569A4good physical and chemical stabilityabsorption is not affected by foodPowder deliveryPharmaceutical non-active ingredients
The present invention provides a sonfenib or donafenib (TKI) oral preparation, comprising a TKI molecular-level mixture and self-assembled polymer materials. The present application also provides an application of the TKI oral preparation. The two self-assembled polymer materials in the TKI oral preparation provided by the present application perform coordinated regulation with TKI guest molecules to reduce premature degradation or efflux of a drug caused by CYP3A4 / A5, CYP2D6, CYP2C8 or P-gp of P450 enzymes in epithelial cells of the gastrointestinal tract mucosa during an absorption process of the oral preparation, and reduce decreased absorption caused by rapid packing after the drug is quickly dissolved out of a molecular-level composition. Therefore, the oral preparation can achieve the same curative effect at a lower dose, features lower Cmax and AUC0-t variations, reduces of the risk of being non-effective or toxic, and would not be affected by food; in addition, the oral preparation significantly reduces dose-related side effects, improves patient compliance, and has good physical and chemical stability.
Owner:BEIJING CREATRON INSTITUTE OF PHARMACEUTICAL RESEARCH CO LTD +1

Lighting module and motor vehicle

The application provides a lighting module (100) comprising: a light source (10) configured to emit light along a main light emitting direction (X) of the lighting module; the lens (20) is arranged in front of the light source, the lens comprises a light inlet surface (21), a light outlet surface (22) and a side surface (23), the light inlet surface and the light outlet surface are oppositely arranged, and the side surface is connected between the light inlet surface and the light outlet surface; wherein the light incident surface is configured to receive the light emitted by the light source, the side surface is configured to reflect at least part of the light, and the light emergent surface is configured to project the light along the main light emergent direction and form a pattern of the light incident surface.
Owner:VALEO VISION SA

Water hose and conveying system

The utility model relates to a water hose and a conveying system, which comprises a water hose body and an electric light-emitting wire, and two ends of the water hose body are respectively a head end and a tail end; the electric light-emitting wire comprises a first conductive wire, a second conductive wire, a first backflow wire and at least two first lamp beads, the first conductive wire and the second conductive wire are arranged in parallel, a plurality of first lamp beads are connected between the first conductive wire and the second conductive wire in parallel, and one end of the second conductive wire and one end of the first backflow wire extend to the head end of the water hose body. The other ends of the second conductor wire and the first backflow conductor respectively extend to the tail end of the water hose body, one end of the first conductor wire extends to the head end of the water hose body, and the other end of the first conductor wire extends to the tail end of the water hose body and is connected with the first backflow conductor; according to the water hose, the problems existing in a traditional light-emitting water hose can be solved, the service life and reliability are guaranteed, and the brightness of the lamp beads is basically the same, so that the electric light-emitting wire can uniformly emit light in the length direction of the water hose body.
Owner:NANJING ZHONGYU FLOW TECHNOLOGY RESEARCH INSTITUTE CO LTD

Lighting module and motor vehicle

The present application provides a lighting module (100) comprising: a light source (10) configured to emit light; the light collector (20) is provided with a reflecting surface (21), and the reflecting surface is configured to collect the light rays emitted by the light source and reflect the light rays into light beams propagating in the main light emitting direction (X) of the illumination module; a first lens (30) disposed in front of the corresponding reflective surface, the first lens being configured to propagate at least part of the light beam; and a second lens (40) configured to project the light beam along the main light exit direction and form an image of the reflective surface.
Owner:VALEO VISION SA

Universal t cell and application thereof

PendingEP4378952A4inability to standardize and large-scale productionlow efficiencyAntibody mimetics/scaffoldsFusion with degradation motif
Provided are a universal T cell (CNK-UT) and an application thereof. The CNK-UT has the broad-spectrum ability to recognize and kill tumor cells and virus-infected cells.
Owner:ST PHI THERAPEUTICS CO LTD

METHOD FOR MANUFACTURING BIOFERMENTED LIQUID FEED, BIOFERMENTED LIQUID FEED AND BIOFERMENTED LIQUID EMULSION FEED

ActiveDK3928633T3increase nutritionPromote digestion
The application relates to a preparation method of liquid bio-fermented feed, liquid bio-fermented feed and bio-fermented emulsion liquid feed, belonging to the technical field of feed preparation. The preparation method of the present application may overcome physiological problems of weaned piglets such as insufficient gastric acid secretion, low content and activity of digestive enzymes, incomplete development of immune system, disorder of intestinal microecosystem and the like. The prepared bio-fermented liquid feed has good palatability and high nutrition, easy digestion, low acidity and is a liquid feed similar to breast milk, which can both effectively alleviate the weaning stress syndrome of piglets, and realizes the perfect transition from breast milk to conventional solid feed.
Owner:TANGRENSHEN GRP CO LTD

Thermoplastic polyester elastomer, resin composition containing said elastomer, and molded articles obtained from these

PendingEP4317317A4Excellent characteristicsGood moldabilityFlexible pipes
The present invention aims to provide a thermoplastic polyester elastomer having particularly excellent extrusion moldability and extrusion molding stability, from which a hollow and long molded article can be stably produced with a uniform thickness for a long time. A polyester elastomer comprising a hard segment made of a polyester constituted of an aromatic dicarboxylic acid and an aliphatic or alicyclic diol and a soft segment made of an aliphatic polycarbonate, wherein the hard segment and the soft segment are bonded to each other, wherein the polyester elastomer is at least partially end-capped with a reactive compound, wherein the reactive compound comprises a polycarbodiimide, wherein the polyester elastomer has an acid value of 15 eq / ton or less, and wherein, under a condition of 230°C, the polyester elastomer satisfies (i) the melt viscosity at a shear rate of 10 / sec after a preheating time of 5 minutes is 1, 800 Pa·s or more, and the melt viscosity at a shear rate of 1,000 / sec after a preheating time of 5 minutes is 800 Pa·s or less; and (ii) a ratio of the melt viscosity measured at a shear rate of 10 / sec after a preheating time of 5 minutes to the melt viscosity measured at a shear rate of 10 / sec after a preheating time of 25 minutes is 0.7 to 1.3.
Owner:TOYOBO MC CORP

Nervendetektionsvorrichtung für ein ablationssystem

An ablation system and a nerve detection device thereof. The nerve detection device includes a power supply module (10), a computation and control module (20), an energy generation module (30) and a blood pressure monitoring module (40). The computation and control module (20) is electrically connected to both the energy generation module (30) and the blood pressure monitoring module (40). The energy generation module (30) is configured to connect to a detecting catheter (50) and to detect a given site in an artery by outputting first energy to the detecting catheter (50). The blood pressure monitoring module (40) is configured to connect to a blood pressure sensor (60). The blood pressure sensor (60) is configured to monitor a patient's blood pressure prior to and during the detecting of the given site by the energy generation module (30) with the first energy and to output the blood pressure monitoring result. The blood pressure monitoring module (40) is further configured to transmit the blood pressure monitoring result to the computation and control module (20). The computation and control module (20) is configured to determine, based on the blood pressure monitoring result, whether there is an ablation target at the given site. The detecting allows accurate location of an ablation target in an ablation procedure, which results in improved effectiveness and safety of the ablation procedure.
Owner:SHANGHAI MICROPORT EP MEDTECH CO LTD

Inhalation device

InactiveEP4295877A4overcome problemsdifficulty and cost is reducedMedical devicesMedical atomisers
Disclosed is an inhalation device, which, by means of a simplified structure, reduces the manufacturing difficulty and cost, and ensures the use effect. In the inhalation device, a filter member closely fits to a capsule placement opening, and when a mouthpiece is clamped to a cover plate, a mesh portion is integrally located in a capsule compartment. Therefore, when a medicinal powder is inhaled, airflow can better pass through the mesh portion under the action of a negative pressure to flow in an ideal flow direction, thereby ensuring the medicinal powder to be effectively inhaled.
Owner:CF PHARMTECH INC

An electrically controlled force pushing structure for the lead frame of a pick-and-place machine

ActiveCN224429262Uovercome problemsImplement push force detectionConstant forceElectric machinery
This utility model discloses an electrically controlled force-pushing structure for a chip mounter's feed lead frame, including a mounting bracket, a sliding seat, a voice coil motor, a first sensor, and a pushing component. The voice coil motor is mounted on the mounting bracket, the sliding seat is fixedly connected to the mover of the voice coil motor, and the pushing component is mounted on the sliding seat. When the resistance applied by the lead frame to the pushing component is greater than the constant force set by the voice coil motor, the mover moves relative to the stator in the opposite direction of pushing, thereby moving the sliding seat to the trigger position with the mover, triggering the first sensor. This utility model connects the voice coil motor, the first sensor, and the pushing component to the sliding seat, transmitting force to the voice coil motor through the sliding seat. When the resistance experienced by the pushing component is greater than the constant force set by the voice coil motor, the sliding seat moves with the mover to the trigger position, triggering the first sensor, thus achieving force detection. The constant force of the voice coil motor in this application is easy to set and can be displayed, overcoming the problems of existing spring-type structures.
Owner:DALIAN JAFENG AUTOMATION CO LTD

Immunoconjugates of an anti-PD-1 antibody with a mutant IL-2 or with IL-15

ActiveMA49033Aincrease preferential activationsuppression of T-cell activity
Owner:F HOFFMANN LA ROCHE & CO AG

Rotation stable projectile wind speed and wind direction estimation method based on kernel extreme learning machine

The invention relates to a rotating stable projectile wind speed and direction estimation method based on a kernel extreme learning machine. Comprising the following steps: establishing a four-degree-of-freedom kinematics model of the rotary stable projectile under a windy condition; constructing a kernel extreme learning machine network model; performing wind speed estimation according to the constructed kernel extreme learning machine network model; the method only needs to determine the connection weight matrix of the hidden layer and the output layer, solves the output matrix of the model on the basis of determining the connection weight matrix, and achieves the estimation of the wind speed and the wind direction. According to the method, a multi-input multi-output model is adopted, the problem that only one variable can be estimated through single estimation is avoided, and the workload is reduced; the network model can be established only by determining the number of the input features, the kernel function and the number of the output features; the number of nodes of the hidden layer does not need to be set, so that the initial weight and bias of the hidden layer do not need to be set, the output weight can be solved on the basis of the least square principle, and the wind speed and wind direction estimation of the projectile is achieved.
Owner:NANJING UNIV OF SCI & TECH

RBDE (Radial Basis Decision Element) algorithm-based robust anti-interference damping control method for wind turbine airfoil

The invention discloses a wind turbine airfoil robust anti-interference damping control method based on an RBDE algorithm, and the method comprises the steps: building a wind turbine airfoil nonlinear vibration model based on a miniature control surface through a wind turbine airfoil aeroelastic model and wind tunnel experiment data; a two-degree-of-freedom internal model control method is utilized to construct a vibration reduction controller K (s) of the wind turbine airfoil; based on the vibration reduction controller K (s) and an LADRC control method, designing a vibration reduction controller Gc (s) of the wind turbine airfoil; designing a driving compensator utau, and combining the driving compensator utau with a vibration reduction controller Gc (s) to obtain a controller g of the wind turbine airfoil; and performing optimization solution on control parameters in the controller g by using an RBDE algorithm. According to the RBDE algorithm provided by the invention, the global search capability of the optimal control parameters is remarkably improved, and the effectiveness and robustness of the set parameters are improved; according to the method, the anti-interference capacity, the vibration reduction control effect and the driving compensation capacity of the wind turbine airfoil under the large-range continuous gust are effectively improved.
Owner:YANGZHOU UNIV