6550 results about "Molecular physics" patented technology

An organic molecule is disclosed comprising:a first chemical moiety with a structure of formula I,andtwo second chemical moieties, each at each occurrence independently from another consisting of a structure of formula II,wherein the first chemical moiety is linked to each of the two second chemical moieties via a single bond.

Described herein are variations of an analyte monitoring system, including an analyte monitoring device. For example, an analyte monitoring device may include a skin-penetrating microneedle array for use in measuring analyte, such as in a continuous manner. The microneedle array may include, for example, at least one microneedle comprising a working electrode comprising an analyte-sensing aptamer that selectively and reversibly binds to analyte. The working electrode comprises at least one thiol-based passivation molecule that provides protection of the working electrode from, by way of example, foulants and interferents. For example, a sensor may be configured to generate a signal that is indicative of a concentration of an analyte in a fluid, the sensor comprising a working electrode comprising an electrode material, a biorecognition layer disposed at least partially on the electrode material and comprising a biorecognition element that selectively and reversibly binds to an analyte, and an at least partially desiccated hydrogel disposed on the biorecognition layer. For example, a working electrode may be configured to generate a signal indicative of a concentration of an analyte in a fluid, the working electrode comprising an electrode material, a biorecognition element disposed on the electrode material that selectively binds to the analyte, wherein the biorecognition element is functionalized with a redox-active molecule and is configured to change conformation upon binding the analyte to move the redox-active molecule, closer to, or further from, the electrode material, and a passivation element comprising a zwitterionic peptide disposed on the electrode material.

Embodiments described herein relate to electrochemical cells with one or more current collectors divided into segments, and methods of producing the same. A current collector divided into segments comprises a substantially planar conductive material including a connection region and an electrode region. The electrode region includes one or more dividers defining a plurality of electron flow paths. The plurality of electron flow paths direct the flow of electrons from the electrode region to the connection region. In some embodiments, the current collector includes a fuse section disposed between the electrode region and the connection region. In some embodiments, the fuse section can include a thin strip of conductive material, such that the thin strip of conductive material melts at a melting temperature and substantially prevent electron movement between the electrode region and the connection region.

The invention relates to the field of Raman spectrums, and discloses a Raman spectrum nonlinear generation method driven by mixed machine learning, which is used for meeting the requirements of a modern Raman spectrum analysis technology on mixture spectrum data with wide coverage, complete types and reliable quality. Comprising the following steps: performing weighted linear combination on pure component spectrums based on a concentration ratio to generate a primary mixture spectrum; the data diversity is enhanced; generating a prediction spectrum; generator parameters are optimized through multi-level feature comparison and adversarial training of the discriminator; matching and deleting false peaks, and reconstructing physical reasonable characteristic peaks; and dynamically adjusting the intensity of the characteristic peak, and outputting high-fidelity spectrum data. According to the method, by fusing physical constraint and deep learning, the peak position precision, intensity consistency and noise robustness of the generated spectrum are remarkably improved, quantitative analysis of a complex mixture in a wide concentration range is supported, and an efficient solution is provided for Raman spectrum database construction and chemical detection.

The invention discloses a reversible background-free hydrogel nanosensor for acetone detection and an intelligent sensing platform, and relates to the technical field of biosensors. The hydrogel nanosensor consists of a hydrogel matrix and an upconversion nanoprobe, and the upconversion nanoprobe comprises upconversion nanoparticles (UCNPs), hydroxylamine sulfate and thymol blue (TB). The invention adopts hydroxylamine sulfate as a specific recognition unit of acetone to construct a reversible luminescent hydrogel probe for acetone detection, and the probe can be reused in multiple detections, thereby reducing the cost of a single detection. In addition, by adopting near-infrared light as an excitation light source, the autofluorescence interference of the hydrogel matrix is ​​effectively avoided, thereby improving the detection accuracy.

Embodiments of improved methods are provided to form ordered structures on a surface of a substrate using direct self-assembly (DSA) of ionic liquid crystals (ILCs). More specifically, various embodiments of methods are provided to control the pitch of a layered structure formed on a substrate surface via self-assembly of ILCs having cation head groups, alkyl tail groups and anions. In the embodiments disclosed herein, the pitch of the layered structure is controlled by: (a) controlling the cation / anion charge ratio of the cation head groups and anions included within the ILCs, and / or (b) adding an ionic liquid to a solution comprising the ILCs.

The invention relates to a back contact solar cell and a preparation method thereof, and a photovoltaic module, the back contact solar cell comprises a substrate, a first surface of the substrate is provided with P-type doped layers and N-type doped layers which are alternately arranged along a first direction, tunneling layers are arranged between the P-type doped layers and the substrate, and tunneling layers are arranged between the N-type doped layers and the substrate. The first fine grid is arranged on the N-type doped layer, and the second fine grid is arranged on the P-type doped layer. A first barrier layer is arranged in the N-type doping layer, the area of the first barrier layer is smaller than that of the N-type doping layer, the projection of the first fine grid falls into the projection of the first barrier layer in the thickness direction of the substrate, and the first barrier layer is used for preventing doping elements in the N-type doping layer and metal crystal grains in the first fine grid from diffusing towards the substrate. And the possibility that the tunneling layer and the substrate are damaged by doping elements and metal crystal grains is reduced. The first barrier layer and the tunneling layer can simultaneously realize selective transportation of carriers, and the efficiency of the back contact solar cell is improved.

Aspects of the present disclosure include methods for spectrally resolving light from fluorophores in a sample. Methods according to certain embodiments include detecting light with a light detection system from a sample having a plurality of fluorophores having overlapping fluorescence spectra and spectrally resolving light from each fluorophore in the sample with a generalized least squares algorithm. In some embodiments, methods include estimating the abundance of one or more of the fluorophores in the sample, such as on a particle. In certain instances, methods include identifying the particle in the sample based on the abundance of each fluorophore and sorting the particle. Methods according to some embodiments includes spectrally resolving the light from each fluorophore by calculating a spectral unmixing matrix for the fluorescence spectra of each fluorophore. Systems and integrated circuit devices (e.g., a field programmable gate array) for practicing the subject methods are also provided.

Disclosed herein is a method and system to generate 3D models of small molecules. The methods and systems are disclosed for an equivariant shape-based virtual screening operation that generates small molecule 3D structures that fit into and bind to a provided protein pocket. The model is configured to learn from existing 3D structures of small molecules in a data-driven manner using forward diffusion and backward diffusion processes to learn and represent the major characteristics of molecule 3D structures. Additional disclosure relates to the model that is further configured to learn from the 3D model of the protein pocket.

The embodiment of the invention relates to a method and a device for predicting optical energy characteristics of organic photovoltaic material molecules. The method comprises the following steps: constructing an optical energy characteristic prediction model for predicting ionization energy, emission energy and absorption energy according to a molecular structure, temperature, pressure intensity and wavelength sequence input by the model; constructing a first data set through data acquisition; training an optical energy characteristic prediction model based on the first data set; after the training is finished, the training is finished; a first molecular structure, a first temperature, a first pressure and a first wavelength sequence input by a user are used as a corresponding molecular structure M, a temperature x, a pressure y and a wavelength sequence Z to be input into an optical energy characteristic prediction model for processing, and ionization energy uIE, an emission energy sequence SEE and an absorption energy sequence SAE which are processed and output by the model are used as corresponding first ionization energy; the first emission energy sequence and the first absorption energy sequence are fed back to the current user. According to the invention, the prediction efficiency can be improved.

To reduce thrust required to convey a charged electrical charge carrier by reducing receding electrostatic force acting in the direction pushing back the electrical charge carrier when the electrical charge carrier is conveyed from a low-potential charging source to a high-potential recovery source, and to keep the potential of the electrical charge carrier low during conveyance.SOLUTION: A potential control layer 73 is provided near a charge retention layer 71 of an electrical charge carrier and the potential is set between that of a charge source and the charge retention layer, thereby reducing the electrostatic force applied to the electrical charge carrier and lowering the potential.SELECTED DRAWING: Figure 6

The invention belongs to the technical field of semiconductor photoelectric devices, and particularly discloses a preparation method for realizing growth of ultralow-defect perovskite single crystals based on steric hindrance control, which comprises the following steps: preparing a perovskite single crystal precursor solution: dissolving a perovskite single crystal precursor in a homogeneous solvent with coordination capability to prepare the precursor solution; and generating a perovskite single crystal seed crystal: heating the prepared perovskite single crystal precursor solution until microcrystals appear, selecting to form good crystals, drying, and storing as the seed crystal for future use. And growing the perovskite single crystal: putting the generated perovskite single crystal seed crystal into the perovskite single crystal precursor solution, heating, and growing to obtain the perovskite single crystal. The preparation method comprises the following steps: dissolving a precursor in a homogeneous solvent with coordination capability through a temperature reversal crystallization method, and adjusting the temperature to carry out single crystal growth; according to the steric hindrance theory, the growth temperature is selected by regulating and controlling the solvent proportion, and the perovskite single crystal with ultralow defect density is obtained.

The present invention relates to the technical field of molecular interaction analysis, and specifically provides a method for analyzing intermolecular interactions. The method comprises the following steps: using a rare earth material with a ligand molecule modified on its surface as an upconversion material, contacting the upconversion material with a target molecule in a solution system, irradiating the solution system with excitation light that matches the rare earth material, and continuously changing the intensity of the excitation light actually received by the upconversion material as the target molecule continuously binds and dissociates with the ligand molecule of the upconversion material in a dynamic process, thereby changing the intensity of the emitted light. By recording the curve of the emission light intensity changing with time, the molecular interaction kinetic constants, such as the binding rate constant (K on ), dissociation rate constant (K off ) and affinity (K D ), etc., which solves the technical problems of low accuracy of existing BLI technology and high cost of SPR technology. Based on the above principles, the present invention has also developed a series of experimental consumables, kits, sensors and analytical devices for molecular interaction analysis.

The present application proposes a liquid crystal display panel and a liquid crystal display, wherein the liquid crystal display panel comprises: an array substrate; a color film substrate, which is arranged in a box with the array substrate; a glue frame, which adheres the color film substrate and the array substrate to form a box body space, and in the cross-sectional direction of the liquid crystal panel, the width of the glue frame gradually increases from one side of the color film substrate to one side of the array substrate; and a liquid crystal layer, which is arranged in the box body space. The liquid crystal display panel and the liquid crystal display proposed in the present application can improve the quality of the liquid crystal display panel.

A quantum-dot-containing composition contains: either quantum dots each having a surface provided with only one equivalent crystal plane, or quantum dots each having a surface provided with two or more different equivalent crystal planes; and one selected from (A), (B), and (C) below: (A) two or more compounds; (B) one or more compounds, and single atoms formed of one or more halogens or chalcogens; and (C) single atoms formed of two or more halogens or chalcogens.

The invention discloses a liquid crystal compound, the structural formula of the liquid crystal compound is as shown in the following formula I, # imgabs0. The liquid crystal compound has large dielectric anisotropy delta epsilon, high elastic constant K, good low-temperature intersolubility, small rotary viscosity gamma 1 and large elastic constant K, the liquid crystal composition containing the liquid crystal composition has large dielectric anisotropy delta epsilon, high elastic constant K, good low-temperature intersolubility, small rotary viscosity gamma 1 and large elastic constant K, and can be used for developing liquid crystal display elements or liquid crystal displays which have high response speed and can effectively improve residual images.

To reduce thrust required for carrying a charge carrier by weakening strong retreating electrostatic force acting on the charged charge carrier, and to increase a conveyable charge amount by weakening potential of the charge carrier being carried, in an electrostatic generator.SOLUTION: A charge control layer remote unit is provided that conducts to a main body of a potential control layer provided in the vicinity of a charge retention layer of a charge carrier and by applying a high voltage of a different polarity of charges charged on a potential control layer body to a charge attraction electrode close to the charge control layer remote unit, charges of the potential control layer main body are moved to a potential control layer remote unit. By increasing potential of the charge carrier and conducting the charge carrier and a recovery electrode, the charges can be safely recovered.SELECTED DRAWING: Figure 10

The invention relates to a light-activated chemiluminescence detection kit for phosphorylated Tau protein p-tau 217 as well as a use method and application of the light-activated chemiluminescence detection kit. The kit comprises a reagent R1, a reagent R2 and a reagent R3, wherein the reagent R1 comprises a luminous microsphere and a first antibody which is coated on the luminous microsphere, is provided with a first tag molecule and can be specifically combined with p-tau 217; the R2 reagent comprises a second antibody with a second tag molecule; the R3 reagent comprises a first pairing molecule capable of being specifically combined with the first tag molecule; the first antibody and the second antibody can be specifically combined with different epitopes of p-tau 217, and one first pairing molecule can be combined with at least two first tag molecules. According to the technical scheme, the capacity of the light-emitting microspheres for receiving active oxygen generated by the light-sensitive microspheres can be improved, the detection sensitivity is improved, and the light-activated chemiluminescence detection requirement of p-tau 217 in plasma is met.

A GaN-based blue-green LED epitaxial structure, relating to the field of semiconductor photoelectric devices. The GaN-based blue-green LED epitaxial structure comprises a substrate, and a buffer layer, a dislocation regulation layer, a U-GaN layer, an N-GaN layer, a multi-quantum-well layer, an electron blocking layer and a P-GaN layer which are sequentially stacked on the substrate, wherein the dislocation regulation layer is of a periodic structure with the number of periods ranging from 2 to 10, and each period comprises a GaN layer and an Si-doped GaN layer that are sequentially stacked. The crystal quality of the epitaxial structure can be improved, thereby improving the light-emitting efficiency and the antistatic performance of the blue-green LED based on the epitaxial structure.

The invention discloses a nano twin copper rough surface direct bonding atomic-scale simulation method, which comprises the following steps: determining an inter-atomic interaction potential function in molecular dynamics through a first principle, constructing a polycrystalline nano twin copper supercell model based on experimental parameters, and generating a rough surface with fractal characteristics; molecular dynamics simulation is adopted to simulate bonding and annealing processes, a bonded polycrystalline nano twin copper model is obtained, and the performance of the interconnection structure is calculated based on the bonded polycrystalline nano twin copper model. The result feedback is used for optimizing the copper-copper direct bonding material and process parameters. According to the method, the atomic-scale polycrystal nano twin copper model is established through simulation, the optimal performance parameter combination of the interconnection structure is obtained, the trial and error cost in tests and production is reduced, the quality of a copper-copper direct bonding interface is improved, and guidance is provided for design and process optimization of high-density packaging.

The invention discloses a high-efficiency near-infrared two-region aggregation-induced emission material, a preparation method thereof and application of the high-efficiency near-infrared two-region aggregation-induced emission material in bimodal surgical navigation. According to the molecular structure, the organic near-infrared two-region material with an intramolecular charge transfer characteristic is constructed by taking thionaphthalene tetracarboxylic acid diimide as an electron acceptor group and tetraphenylethylene as a molecular rotor and an electron donor unit. By expanding the length of a pi conjugate fragment and introducing an isotope effect, the oscillator strength can be improved, and high-frequency vibration can be inhibited, so that the radiative transition rate of molecules is promoted, and the non-radiative transition rate is inhibited. The nanoparticles prepared from the aggregation-induced emission material have the advantages of high brightness, large Stokes shift and good light stability, and have an excellent effect in bimodal imaging guided mouse in-situ breast cancer and sentinel lymph node operation excision.

The present disclosure provides a semiconductor green laser. The semiconductor green laser, from bottom to top, comprising a substrate, a lower limiting layer, a lower waveguide layer, an active layer, an upper waveguide layer, and an upper limiting layer. The active layer is a quantum well composed of well layers and barrier layers. Each of the well layers includes any one of AlInGaN, AlInN, AlGaN, AlN, InN, InGaN, and GaN, or any combination thereof. Each of the barrier layers includes any one of AlInGaN, AlInN, AlGaN, AlN, InN, InGaN, and GaN, or any combination thereof. An electron effective mass of each of the well layers is less than an electron effective mass of each of the barrier layers. A spontaneous polarization coefficient of each of the well layers is less than a spontaneous polarization coefficient of each of the barrier layers.

A liquid crystal on silicon (LCoS) and a wavelength selective switch (100), which are used for providing an LCoS device capable of realizing polarization independence, and can also ameliorate the problem of secondary crosstalk occurring due to a residual of unconverted deflection, thereby ensuring the application of the LCoS. In the LCoS, an extra phase is pre-added in a dispersion direction on the basis of structures such as a meta-surface design or a phase film; and by means of the pre-added extra phase, unconverted polarization light forms a high-frequency deflection or a scattering phase deviates the energy of the unconverted polarization light from a crosstalk level, so as to prevent the crosstalk of the unconverted polarization light and converted polarization light, thereby implementing the suppression of secondary crosstalk in a port direction.

A semiconductor structure is provided. The semiconductor structure includes a substrate, a target layer on the substrate, and a hard mask layer doped with a group IV-A element on the target layer. The number of sp3 orbital bonds in the hard mask layer is greater than the number of sp2 orbital bonds.

A super-resolution light-sheet fluorescence microscopy method, comprising: using reversibly photoswitchable fluorescent proteins (RSFPs) to process a biological sample (1000) to be tested; using a light sheet as activation light to be incident onto said biological sample (1000), so as to generate an activated portion in the reversibly photoswitchable fluorescent proteins (RSFPs); using modulated striped structured light as excitation light to be incident onto the activated portion of the reversibly photoswitchable fluorescent proteins (RSFPs) towards a surface where the activated portion is located, such that the activated portion of the reversibly photoswitchable fluorescent proteins (RSFPs) on a plane where the light sheet is incident emits fluorescence, wherein the activation light and the excitation light have different wavelengths; and collecting a fluorescence image with structured light stripe information as a two-dimensional fluorescence image for super-resolution image processing. Further provided is a super-resolution light-sheet fluorescence microscopy system.

The invention discloses a method and device for predicting protein-ligand binding affinity based on distance and atomic contact number, comprising: acquiring a data set of protein-ligand binding affinity, the data set comprising: atomic information of a protein receptor and atomic information of a ligand; classifying atoms of a protein-ligand compound in the data set according to a preset atom type, and calculating a distance and an atom contact number of an atom pair of a protein-ligand in the data set according to the atom type; training a preset model by taking the protein-ligand distance and the atom contact number as training data to obtain a protein-ligand binding affinity prediction model; and obtaining to-be-predicted protein-ligand data information, inputting the to-be-predicted protein-ligand data information into the protein-ligand binding affinity prediction model, and outputting the to-be-predicted protein-ligand binding affinity. The method is not limited to the power exponent of the distance in the traditional electrostatic interaction energy and Van der Waals interaction energy, and the prediction capability of the affinity is improved.

A liquid crystal optical system includes a variable polarization electro-switchable device forming a variable polarizer, the variable polarizer including first and second transparent electrodes with an electric field between the first and second electrodes, the first and second electrodes are coplanar, forming an alternation of first and second electrically conductive strips—at distinct potentials, and an electroactive layer made of a material including liquid crystals which are nematic and dichroic dyes.

A liquid crystal panel includes a first transparent substrate, a first electrode, a liquid crystal layer, a second electrode, and a second transparent substrate in this order, in which the liquid crystal layer contains polymer dispersed liquid crystal and / or guest-host liquid crystal containing a dichroic dye, and includes a transparent region and a switching region switched between a transmitting state and a scattering or absorption state by including an overlapping region overlapping the second electrode and a non-overlapping region not overlapping the second electrode.

The invention provides an intermediate layer structure for a solar cell and a preparation method and application thereof. The intermediate layer structure comprises a transparent conductive oxide layer, a self-assembled monomolecular hole transport layer and a self-assembled monomolecular connecting layer for connecting the transparent conductive oxide layer and the self-assembled monomolecular hole transport layer, the material of the self-assembled monomolecular hole transport layer is a self-assembled monomolecular material with a phosphonic acid end group; the material of the self-assembled monomolecular connecting layer is selected from one or two of a silane self-assembled monomolecular layer material or a carboxylic acid self-assembled monomolecular layer material, and the silane self-assembled monomolecular layer material and the carboxylic acid self-assembled monomolecular layer material have sulfydryl groups; the problems that in the prior art, the material coverage rate of a self-assembled monomolecular hole transport layer on a TCO is low, and the material distribution of the self-assembled monomolecular hole transport layer is not uniform are solved.

A method for driving a cholesteric liquid crystal display, wherein the method includes steps as follows: Firstly, a reflective cholesteric liquid crystal panel including a pixel array composed of a plurality of pixel units is provided. Next, a scanning operation is performed on the pixel array. The scanning operation includes steps as follows: A continuous fixed pulse is applied to at least one of the plurality of pixel units lasting for a time period, so as to make a cholesterol liquid crystal layer of the at least one of the plurality of pixel units having a uniform lying helix (ULH) phase; and a maintaining pulse that is smaller than the continuous fixed pulse is applied to the at least one of the plurality of pixel units.