810 results about "Quantum yield" patented technology

The invention provides a boron-nitrogen heterocyclic compound as well as an intermediate and a preparation method thereof, the boron-nitrogen heterocyclic compound has a structure as shown in a general formula (1), and is prepared by taking compounds as shown in a formula A, a formula B and a formula C as intermediates. Compared with similar carbon skeleton molecules, the boron-nitrogen heterocyclic compound provided by the invention shows an excellent narrow-band luminescence property. The half-peak width of the emission spectrum of the boron-aza compound is as low as 6.4 nm, and meanwhile, the fluorescence quantum yield is as high as 97%.

The invention relates to the technical field of luminescent materials, and discloses a preparation method and application of a transition metal and chalcogen ion doped metal halide high-efficiency wide-spectrum luminescent material, the chemical formula of the transition metal and chalcogen ion doped metal halide is Cs2Sn1-x-yCl6: x% Te < 4 + >, yMo < 4 + >, the ultra-wideband fluorescent powder converted light emitting diode (LED) covers the range from visible light (VIS) to near infrared light (NIR), and shows remarkable potential in practical application. According to the invention, ultra-wide spectrum emission from 400 nm to 1400 nm is realized in Mo < 4 + >-Te < 4 + > co-doped Cs2SnCl6, and the photoluminescence quantum yield of 95.3% is achieved, the excellent performance is realized through efficient energy transfer from Te < 4 + > to Mo < 4 + > and passivation synergistic effect of vacancy defects, and the performance can be verified through theoretical calculation and spectral research; finally, the ultra-wideband fluorescent powder conversion LED based on the Mo < 4 + > and Te < 4 + > co-doped Cs2SnCl6 is successfully prepared and is applied to the fields of blood gas analysis and night vision imaging.

The invention belongs to the technical field of organic synthesis, and particularly discloses an ammonia aromatic alkene modified near-infrared BODIPY fluorescent probe as well as a preparation method and application thereof.The near-infrared BODIPY fluorescent probe is obtained by adopting 6-(dimethylamino) nicotinic aldehyde to directionally modify the alpha position of BODIPY and constructing an expanded conjugated system through Knoevenagel condensation. Wherein dimethylamino provides a strong electron donating effect, a molecular structure is twisted into a non-planar configuration due to steric hindrance of a pyridine ring, pi-pi accumulation is reduced, and an ACQ effect is inhibited. According to the structural modification strategy, significant red shift of absorption / emission wavelength is realized by expanding a molecular pi-conjugated skeleton, and meanwhile, the stability of the BODIPY core and the quantum yield are effectively enhanced. The probe molecule can specifically recognize the diphenylalanine dipeptide structural unit by utilizing the synergistic coordination effect of the 2-aminopyridine derivative and the BODIPY mother nucleus, so that the selective detection of the Alzheimer's disease biomarker Abeta42 is realized, and a novel optical detection tool is provided for the early molecular diagnosis and targeted therapy of AD (Alzheimer's disease).

The invention relates to a high-efficiency near-ultraviolet heat exciton compound with circular polarization property and application of the high-efficiency near-ultraviolet heat exciton compound in preparation of a circular polarization organic electroluminescent device, and belongs to the technical field of organic photoelectric materials. The organic electroluminescent material is a high-efficiency near-ultraviolet heat exciton compound with circular polarization property, nine pairs of near-ultraviolet enantiomers are successfully designed and synthesized by combining chiral group binaphthol with fluorene with high luminous efficiency, and the nine pairs of near-ultraviolet enantiomers all show obvious circular polarization luminous property and high fluorescence quantum yield. The electroluminescent devices prepared based on the nine pairs of near ultraviolet enantiomers all show near ultraviolet emission, and the external quantum efficiency is 3.9%, 3.1%, 4.5%, 7.5%, 6.3%, 5.0%, 10.3%, 9.2% and 11.6% respectively. A new visual angle is provided for developing a near ultraviolet heat exciton material with circular polarization luminescence and high efficiency at the same time, and 3D and wide color gamut display can be directly achieved in the future.

The invention relates to the technical field of organic and inorganic hybrid functional materials, in particular to a doped chiral metal halide material with light-induced circular polarization luminescence and a preparation method and application of the doped chiral metal halide material, the chemical formula of the doped chiral metal halide material is L2BnC1-nX4, and the value of n is 0 lt; n is less than 1. The fluorescence quantum yield of a film sample is remarkably improved by using a transition metal ion or rare earth ion doping method. According to the invention, the plug splitting energy in the chiral metal halide is adjusted, so that the chiral optical property of the film material is remarkably improved. The preparation process of the chiral metal halide thin film is simple, the thin film does not need to be prepared after a single crystal material is obtained through a harsh single crystal preparation method, and the material composition and the doping proportion can be easily adjusted according to the requirements of material properties. The invention provides a feasible way for regulating and controlling the chiral optical property of the chiral metal halide by doping transition metal ions or rare earth ions.

The invention discloses an aggregation-induced emission fluorescent compound with near infrared (NIR) luminescence. The fluorescent compound is wrapped by a polymer matrix to form a nano aggregate, which proves that the fluorescent compound shows excellent photothermal conversion efficiency while maintaining high fluorescence quantum yield. Therefore, compared with the mode of relying on high permeability and retention (EPR) effect, the nanometer aggregate accumulation guided by the photo-induced thermoacoustic effect (PTA) can further improve the photo-thermal treatment effect. In-vitro and in-vivo verification further confirms that the nano-aggregate shows excellent fluorescence-guided optical diagnosis and treatment capability in the aspect of tumor elimination.

The invention provides a luminescent material containing a cyclobutadiene structure, and a preparation method and application thereof, and relates to the technical field of organic electroluminescent materials. According to the cyclobutadiene-containing luminescent material provided by the invention, the anti-aromatic cyclobutadiene is fused into a binary nitrogen-containing fused heterocyclic skeleton, and excitation state vibration relaxation is inhibited by using the special electronic structure and high ring tension of the anti-aromatic cyclobutadiene, so that narrow-band luminescence is realized. By introducing the steric hindrance effect group, the aggregation fluorescence quenching phenomenon between luminescent parent nuclei is weakened, and the fluorescence quantum yield is improved. Different from a current mainstream multi-resonance mechanism, the design of the narrow-spectrum light-emitting molecule provided by the invention does not need to depend on the construction of a B / N-fused ring, and the molecular structure can be simplified to realize full-light-color ultra-narrow-band light emission. When the organic light-emitting diode is applied to an organic light-emitting device, an ultra-narrow full-width-at-half-peak electroluminescent spectrum and high device efficiency can be realized, and a better solution is provided for an ultra-high-definition organic light-emitting diode display technology.

The invention provides an aza-BODIPY molecule with NIR-II fluorescence emission and I-type photodynamic activity and a preparation method thereof. The aza-BODIPY molecule has good light absorption in a near-infrared (NIR) region, the emission peak of the aza-BODIPY molecule is prolonged to a near-infrared second region (NIR-II), and the aza-BODIPY molecule shows an ultrahigh NIR-II fluorescence quantum yield of 13%. Meanwhile, the photosensitizer prepared by adopting aza-BODIPY molecules can effectively generate I-type active oxygen species, namely superoxide anion free radicals, under the excitation of 808nm laser. On the basis, high-resolution tumor fluorescence imaging can be realized by utilizing NIR-II fluorescence of the aza-fluorine boron fluorescent sensitizer, and the aza-fluorine boron fluorescent sensitizer is used for accurate and efficient NIR-II fluorescence imaging mediated I-type photodynamic therapy of deep tumor tissues.

The invention discloses a high-color-purity near ultraviolet heat exciton compound with circular polarization property and application thereof in preparation of a circular polarization organic electroluminescent device, and belongs to the technical field of organic photoelectric materials. The electroluminescent material disclosed by the invention is a high-color-purity near ultraviolet heat exciton compound with circular polarization property, and two pairs of near ultraviolet enantiomers are successfully designed and synthesized by combining a chiral group binaphthol, a weak donor dibenzothiophene, dibenzofuran and an acceptor cyanophenyl; the compounds show obvious circular polarization luminescence property and high fluorescence quantum yield. The electroluminescent devices prepared based on the enantiomers all show near ultraviolet emission, CIE coordinates are respectively (0.168, 0.040) and (0.166, 0.040), and the external quantum efficiencies are respectively 4.3% and 3.4%. According to the near ultraviolet heat exciton material, a new visual angle is provided for developing the near ultraviolet heat exciton material with circular polarization luminescence and high color purity at the same time, and 3D and wide color gamut display can be directly achieved in the future.

The invention discloses a near-infrared two-region aggregation-induced emission material as well as a preparation method and application thereof, and belongs to the technical field of aggregation-induced emission materials. The invention provides a fluorescent material with aggregation-induced emission (AIE) property, which can have high luminous efficiency in an NIR-II (1000 nm to 1500 nm) region. The invention aims to carry out rational structure design through the multilevel space confinement effect of molecule and aggregate levels. Through modification of a methyl group and a side chain substituent group, free rotation of an aromatic ring is effectively inhibited, and a rigid mortise and tenon interlocking structure is formed in the crystal. The water-soluble nanoparticles prepared from the synthesized aggregation-induced emission material can achieve a fluorescence quantum yield of 28.2%. By utilizing the nanoparticles with high fluorescence efficiency, the application of real-time dynamic monitoring and the like on intestinal vessels of a living body can be realized, and a new method is provided for early diagnosis and surgical intervention of acute intestinal ischemia.

The invention relates to the technical field of medical chemistry, in particular to a bridge oxygen site regulatively modified rhodamine anti-cancer fluorescent compound as well as a preparation method and application thereof. The invention develops the rhodamine anti-cancer fluorescent compound of which the meso site is functionalized by tetraarylethene and the bridge oxygen site can be regulated and modified, the fluorescent compound has adjustable red light-near infrared fluorescence emission and excellent fluorescence quantum yield, and the quantum yield can be as high as 99%; the fluorescent compound specifically targets mitochondria, and mainly inhibits growth of tumor cells by inducing para-apoptosis; under irradiation of 655 nm near-infrared laser, ferroptosis is further triggered, efficient treatment of tumor cells is achieved through chemical-photodynamic synergistic effect, and a new treatment thought is provided for overcoming tumor drug resistance.

Provided is a semiconductor nanoparticle complex in which a ligand is coordinated to a surface of a semiconductor nanoparticle. The semiconductor nanoparticle is a core-shell type semiconductor nanoparticle including a core containing In and P and one or more layers of shells, wherein at least one of the shells is formed of ZnSe. The ligand includes one or more kinds of mercapto fatty acid esters represented by the following general formula (1): HS—R1—COO—R2 (1). The mercapto fatty acid ester has an SP value of 9.20 or more. The mercapto fatty acid ester has a molecular weight of 700 or less, and the average SP value of the entire ligand is 9.10 to 11.00. The present invention provides a semiconductor nanoparticle complex dispersible at a high mass fraction in a polar dispersion medium while keeping high fluorescence quantum yield (QY) of semiconductor nanoparticles.

The invention provides a benzobis (thiadiazole) near-infrared two-region fluorescent dye molecule and a preparation method thereof, and the preparation method comprises the following steps: by taking a benzobis (thiadiazole) derivative as a raw material, introducing 3, 4-ethylenedioxythiophene through a Stille cross-coupling reaction; the preparation method comprises the following steps: carrying out bromination with N-bromosuccinimide, introducing a cyanated dibenzocarbazole derivative through a Suzuki cross-coupling reaction, and finally carrying out reduction and cyclization reactions to synthesize the end cyano-functionalized near-infrared two-region fluorescent small molecular dye. The receptor-donor-receptor-donor-receptor (A '-D-A-D-A') structure near-infrared two-region fluorescence molecule disclosed by the invention has the properties of long absorption wavelength, high fluorescence quantum yield, high fluorescence brightness and the like, and has a wide application prospect in the field of near-infrared two-region fluorescence imaging.

The preparation method comprises the following steps: carrying out reflux reaction on 4-bromo-1, 8-naphthalic anhydride and primary amine in an organic solvent to obtain an intermediate product, and carrying out C-N coupling reaction on the intermediate product, a compound containing a nitrogen secondary amine electron-donating group, alkali and a catalyst in the organic solvent to obtain the double-state emission fluorescent dye. The two-state emission dye is obtained. An amino auxochrome group of a bridge ring structure is modified in a 4-bromine-1, 8-naphthalimide parent, the fluorescence quantum yield of the dye in a polar solvent is improved through the characteristic that nitrogen atom lone pair electrons of the nitrogen-containing bridge ring structure are not easy to overturn, and pi-pi stacking, which is not beneficial to emission, of the dye is inhibited through the large steric hindrance effect of the bridge ring structure; the dye shows bright fluorescence emission in non-polar and polar solvents, also has a very strong fluorescence quantum yield in a solid state, and shows a quantum yield greater than 94% when the dye is dispersed in an EVA (Ethylene-Vinyl Acetate) film.

The invention provides a high-fluorescence modulatable carbon quantum dot as well as a preparation method and application thereof, and belongs to the technical field of luminescent devices. The preparation method comprises the following steps: mixing a carbon source, an auxiliary agent and a passivator in a solvent to obtain carbon quantum dots; and modifying the carbon quantum dots by using a surface modifier to obtain the modified carbon quantum dots with different surface wettability. The prepared modified carbon quantum dot has the characteristics of high fluorescence quantum yield, adjustable wettability, stable and controllable fluorescence color, easiness in dispersion in organic materials, long service life and the like. The carbon quantum dot can be used as an ideal light conversion material to be applied to the photovoltaic field, the anti-counterfeiting field and the like.

The invention discloses an ether chain modified rhodamine fluorescent dye, an ether chain modified rhodamine fluorescent dye probe and a preparation method and application thereof, through modification of an ether chain, the water solubility of the rhodamine dye is improved, the aggregation quenching effect is reduced, meanwhile, the intramolecular torsional charge transfer (TICT) is reduced through the electron withdrawing effect of oxygen atoms, and the fluorescence sensitivity is improved. Finally, the quantum yield of the rhodamine dye is greatly improved. The quantum yield of ether chain modified oxygen rhodamine water is increased from 0.31 to 0.70, and the quantum yield of silicon-based rhodamine water is increased from 0.19 to 0.41. The rhodamine dye disclosed by the invention has the characteristics of high brightness, easiness in functional derivation and the like, and has application prospects in the fields of fluorescent probes, fluorescent labels, super-resolution fluorescence imaging and the like.

The invention relates to the technical field of organic synthesis and the technical field of fluorescent materials, in particular to a boron coordination salicylhydrazone double-state emission fluorophore as well as a preparation method and application of the boron coordination salicylhydrazone double-state emission fluorophore. The structure of the boron coordination salicylazone double-state emission fluorophore is shown as I, II or III; wherein R1 is selected from one of H, halogen atoms, diethylamino and thienyl, R2 is selected from one of H, halogen atoms, diethylamino and thienyl, and R3 is selected from one of aryl, 9, 9 '-spirobifluorenyl, alkoxy and halogen atoms. The boron coordination salicylazone double-state emission fluorophore is diversified in structure and good in solubility, has excellent photophysical properties and extremely high quantum yield, and also shows excellent biocompatibility and remarkable liposome targeting property at the same time. Moreover, the preparation method of the boron-coordinated salicylazone double-state emission fluorophore adopts a one-pot two-step method, is simple and convenient, is high in yield, is green and environment-friendly, and has a wide application prospect.

The invention belongs to the field of photoelectric materials, and particularly relates to a vacuum vapor deposition perovskite material crystallization method, which is characterized in that vacuum vapor deposition of a perovskite precursor is carried out step by step, and a specific additive containing amide, amino, carboxyl and other functional groups is introduced in the deposition process to realize dynamic regulation and control of perovskite grain growth. According to the method, the perovskite crystallization kinetic process can be regulated and controlled, so that the crystallization of perovskite is optimized, the quality of the film is improved, the defects of the perovskite film are reduced, and the fluorescence quantum yield is improved.

The invention provides a preparation method of nitrogen and phosphorus-doped carbon dots and application of the nitrogen and phosphorus-doped carbon dots in quercetin detection, the nitrogen and phosphorus-doped fluorescent carbon dots (N, P-CDs) are successfully constructed for the first time by adopting a hydrothermal synthesis method, and the carbon dots have emission peaks at 465 nm under the excitation wavelength of 325 nm and show green fluorescence under the irradiation of an ultraviolet lamp; quinine sulfate is used as a standard reference substance, and the quantum yield is 1301%; an N, P-CDs solution is used as a probe molecule, after quercetin is added, fluorescence quenching of N, P-CDs is induced, and the concentration of quercetin and the fluorescence intensity of N, P-CDs are linearly changed, so that the method can be used for quantitative detection of quercetin. The N, P-CDs preparation method provided by the invention is simple and rapid, the product property is stable and non-toxic, the detection sensitivity on the quercetin is high, and the N, P-CDs can be used for detecting the content of the quercetin in serum.

The invention belongs to the technical field of antitumor drugs, and particularly discloses a preparation method and application of a compound for near-infrared fluorescence imaging and photothermal-photodynamic synergistic treatment. The compound for near-infrared fluorescence imaging and photothermal-photodynamic synergistic treatment is shown in the following structural formula: # imgabs0, the molecular skeleton of the compound contains a triphenylamine unit and an N, N-dimethylaniline fragment, intramolecular rotation limitation and intramolecular vibration limitation can be generated, and obvious aggregation-induced emission (AIE) performance is shown. The function-integrated phototherapy agent has high active oxygen generation efficiency, photothermal conversion efficiency and near-infrared fluorescence quantum yield, and is beneficial to obtaining ideal photothermal-photodynamic therapy effect for deep tumors. The phototherapy agent is novel in structure, the preparation method is easy in raw material obtaining, the synthesis condition is mild, the preparation method is simple, purification is convenient and fast, implementation is easy, and the phototherapy agent has great application prospects.

The invention discloses a compound, a kit and application thereof, and relates to the technical field of biomedicine. The compound comprises an electron acceptor aromatic unit, an optional electron donor aromatic unit and a shielding unit, and the shielding unit shields intermolecular interaction of the electron acceptor aromatic unit and / or the electron donor aromatic unit. Wherein the electron acceptor aromatic unit, the electron donor aromatic unit and the shielding unit are connected through covalent bonds. The compound can be used as a molecular near-infrared-II fluorophore, and has higher quantum yield and good biocompatibility. The compounds emit fluorescence in the range of 900-1400 nanometers, the intermolecular and intramolecular interaction of the conjugated skeleton is weakened, and the quantum yield is improved. The high quantum yield, biocompatibility and near-infrared II emission of the compound provide opportunities for in-vivo application of near-infrared II imaging by using molecular fluorophores.

The invention discloses a fluorescent probe as well as a preparation method and application thereof. The invention provides a series of fluorescent probes with novel structures, and the fluorescent probes take 2-(isoquinoline-1-yl) pyrrole boron difluoride as fluorophores, so that the fluorescence quantum yield of the probes is improved, the detection resolution of nitric oxide is increased, and the detection sensitivity is improved. The fluorescent probe disclosed by the invention has the characteristics of large Stokes displacement, high fluorescence quantum yield, good selectivity and short response time.

The invention belongs to the technical field of light-emitting hybrid materials, and particularly discloses a preparation method and application of an efficient blue light emitting hybrid material. The preparation method comprises the following steps: dispersing cuprous halide, triphenylphosphine (tpp) and tetraethylammonium halide in N, N-dimethylformamide (DMF) according to a molar ratio of 1: 1: 1 to form a uniform solution, and performing ultrasonic treatment at room temperature to generate luminescent powder; and washing, centrifuging and drying in vacuum to obtain the hybrid material. The highest photoluminescence quantum yield is up to 70%, and the luminescence mechanism is thermally activated delayed fluorescence. The material can be used for a white light LED (CIE coordinate (0.33, 0.33)) and an X-ray scintillator (the light yield is 32537 photons / MeV, and the spatial resolution is 20lpmm <-1 >), and has the characteristics of simple preparation and excellent performance.

Provided are a photoelectric conversion element and an imaging element which are excellent in response speed and exhibit a high external quantum yield, and a photoelectric conversion element material that contributes to production of these elements. An imaging photoelectric conversion element (100) includes a layer containing a photoelectric conversion element material represented by formula (1) below, where EWG represents an electron-withdrawing group, L represents an aromatic hydrocarbon group having 6 to 30 carbon atoms, n represents 1 to 8, k represents 0 to 2, and p represents 1 to 8, where p is 1 if k is 0.

The invention discloses a red fluorescent silicon nanodot as well as a preparation method and application thereof. The method comprises the following steps: S1, weighing sulforhodamine 101, adding ultrapure water for dissolving, then adding N-(2-aminoethyl)-3-aminopropyltrimethoxysilane, uniformly stirring, transferring the obtained mixture into a reaction kettle, and heating for reaction; and S2, after the reaction is finished, cooling to room temperature, purifying the obtained product by using a silica gel chromatographic column, eluting by using an eluent, collecting the eluent, and finally, freeze-drying to obtain the red fluorescent silicon nanodots. Compared with common blue-green fluorescence, red fluorescence emission has deeper tissue penetrability and background fluorescence interference resistance; the silicon nanodot provided by the invention not only has excellent light stability and high quantum yield, but also has characteristics similar to lipophilic cations, and can specifically target mitochondria in living cells; in addition, the silicon nanodots also show excellent imaging ability in zebrafish embryos and juvenile fish bodies.

The invention discloses a bifunctional fluorescent molecular probe, a preparation method thereof and application of the bifunctional fluorescent molecular probe in polarity detection of ONOO <-> and lipid droplets, and belongs to the technical field of polarity detection of ONOO <-> and lipid droplets. The problems that a fluorescent probe is only limited to detection of a single analyte, and targeted monitoring of lipid droplets in cells and simultaneous detection of endogenous ONOO <-> in the cells cannot be achieved are solved. According to the invention, a dual-response fluorescent molecular probe PTQ based on a triphenylamine group is prepared, and the PTQ shows dual response to a polar environment and dynamic change of ONOO <->. Test results show that the fluorescent probe shows high sensitivity (1.92 nM), stable fluorescence signals and high quantum yield (57.76%) in a low-polarity medium, also has excellent ONOO <-> selectivity, low detection limit (4.97 nM), low toxicity and excellent biological imaging ability, and realizes targeted monitoring of lipid droplets and detection of endogenous ONOO <-> in cells.

The invention provides a europium ion doped titanate compound as well as a preparation method and application thereof, and relates to the technical field of rare earth luminescent materials. The chemical formula of the titanate compound provided by the invention is K2Ti6O13: xEu < 3 + >, the titanate compound is in a monoclinic system. A proper amount of Eu < 3 + > ions are doped in K2Ti6O13, so that the prepared rare earth fluorescent powder has higher color rendering index and quantum yield, and the luminescent property of a white light LED can be greatly improved; as K2Ti6O13 has good electrochemical performance and relatively high conductivity, the rare earth fluorescent powder provided by the invention can also be used in the fields of illumination, display, photocatalysis and energy storage. And on the other hand, the preparation method provided by the invention is simple in process, mild in condition, convenient for large-scale production and wide in development and application space.

The invention belongs to the technical field of singlet oxygen generation, and discloses an efficient singlet oxygen generation photosensitizer based on nitrogenous aliphatic ring size regulation and a theoretical calculation design method. A donor is introduced to the meso site of stilbene-BODIPY, the ring tension of the stilbene-BODIPY is effectively changed by adjusting the size of a nitrogen-containing ring, and the larger the ring tension is, the more unstable the molecule is, so that the oxidation potential of the donor is reduced, and the electron donating ability of the stilbene-BODIPY is further improved. The donor with stronger electron donating ability can obviously improve the intersystem crossing efficiency of photosensitizer molecules, thereby improving the quantum yield of singlet oxygen. According to the donor designed by the invention, the electron donating capability of the donor can be enhanced by adjusting the size of the nitrogen-containing aliphatic ring, the spin-orbit coupling is increased, and intersystem crossing is promoted. The calculation result shows that the photosensitizer has lower oxidation potential, smaller single triplet state energy gap, larger spin-orbit coupling coefficient and higher intersystem crossing rate, and shows more excellent potential in the field of singlet oxygen generation.

The present invention discloses the application of a water-soluble and positively charged fluorescent probe TPA-3Py for the detection of sodium heparin. TPA-3Py is obtained by covalently connecting three methylated vinylpyridines to the three arms of a triphenylamine molecule respectively. Heparin can induce the aggregation-induced emission effect of this fluorescent molecule. With the increase of the heparin content, the fluorescence intensity increases significantly, showing a good fluorescence turn-on response, overcoming the deficiency that the fluorescence probe quenches due to aggregation during the detection of heparin in the prior art. When a 10 μM aqueous solution of TPA-3Py is used for the detection of heparin, a stable fluorescence intensity is achieved within 5 minutes, the linear range is 0 - 6.14 mg / L (R<supgt;2< / supgt> = 0.9938), the lowest detection limit is 49.53 ng / mL, and the quantum yield reaches 4.85%. For the detection of sodium heparin, the TPA-3Py probe adopted in the present invention overcomes the quenching phenomenon caused by aggregation and exhibits a significant AIE effect. The fluorescent probe TPA-3Py for the detection of sodium heparin in the present invention has high sensitivity, high fluorescence intensity, rapid response and stable signal. The fluorescent molecular structure of TPA-3Py is simple, and the detection method is simple and easy to implement, which is worthy of popularization and application in the determination of the sodium heparin content.

The utility model relates to a diagnostic imaging system and a radiation detector thereof. The radiation detector comprises an anode assembly, a cathode assembly, a conversion assembly and an irradiation assembly. In the diagnostic imaging system, radiation penetrates through the cathode assembly and reaches the conversion assembly, visible light and / or infrared light are / is emitted through the irradiation assembly to irradiate the conversion assembly, so that the radiation can be converted into electrons and holes in the conversion assembly, the electrons can be collected by the anode assembly, and the electrons are collected through the anode assembly. Therefore, the number change of electrons can be detected at the contact position of the signal generator and the anode assembly, the electrons can be converted into radiation site signals, radiation penetrating through a to-be-imaged object is detected, the transparent electrode is transparent to infrared light and / or visible light, the photoinduced quantum yield is increased, and the imaging quality is improved. The above effects improve the stability of the radiation detector in a radiation use environment.