74 results about "Stokes shift" patented technology

The invention belongs to the technical field of organic radiation luminescence and radiation imaging, and discloses an aggregation-induced delayed fluorescence (AIDF) type organic scintillator material and a preparation method thereof, and a preparation method and application of a flexible organic scintillation film. The molecular structure of the material comprises carbonyl, methylene, sulfuryl and other connecting units, phthalonitrile is used as an acceptor unit, carbazole is used as a donor unit, an aggregation-induced excitation state is formed through space charge transfer among molecules, efficient AIDF luminescence and large Stokes shift characteristics are realized, the self-absorption phenomenon is effectively avoided, and the luminescent efficiency is improved. The X-ray fluorescence probe is suitable for a luminescence process under an X-ray excitation condition, the sensitivity of X-ray detection is remarkably improved, and the lowest detection limit can reach 276nGy.s <-1 > and is far superior to the 5.5 mu Gy.s <-1 > standard required by medical diagnosis. Besides, the flexible scintillator film prepared based on the material system radiates and emits light within the waveband range of 450-750 nm and is perfectly matched with the response area of a silicon-based detector, X-ray imaging with the high signal-to-noise ratio is achieved, and the imaging resolution is as high as 20.01 lp.mm <-1 >.

The invention discloses a near-infrared fluorescent probe based on a xanthene-quinoline conjugated skeleton for detecting Cu < 2 + > as well as a preparation method and bioimaging application of the near-infrared fluorescent probe. The molecular formula of the fluorescent probe is C34H32N4O2. Based on the strategy of inhibiting the PET process, the large Stokes shift near-infrared fluorescent probe for specifically recognizing Cu < 2 + > is constructed, and spectrum experiments show that the probe has excellent recognition performance on Cu < 2 + >, the emission wavelength is 720 nm, and the Stokes shift reaches 170 nm; (2) the specificity is high, and Cu < 2 + > and other biological related metal ions can be effectively distinguished; (3) low detection limit (LOD = 17.6 nM); (4) quick response dynamics (lt; 30s) for a motor vehicle. More importantly, the probe XQ-NH2 is successfully applied to Cu < 2 + > imaging in living cells and living mice, it is proved that XQ-NH2 not only can provide a reliable technical means for Cu < 2 + > detection and imaging research in a complex biological system, but also shows that XQ-NH2 has important application potential in related fields.

The present invention relates to the technical field of luminescent materials and preparation methods thereof, and discloses a broadband white light cluster and a preparation method thereof. The broadband white light cluster has the general chemical formula: x Cu y I z αH2O, where A comprises at least one alkylamine. The broadband white-light cluster luminescent material of the present invention has an excitation peak in the ultraviolet region, making it well compatible with commercial UV chips. Its emission peak width covers 400-800nm. Its large Stokes shift (150nm) effectively prevents reabsorption. By controlling the pressure within which the broadband white-light cluster luminescent material is exposed, the present invention achieves luminescence enhancement and spectral control. The broadband white-light cluster luminescent material of the present invention utilizes inexpensive raw materials, has a simple synthesis process, operates at a low temperature, and exhibits stable chemical properties and is pollution-free, making it suitable for large-scale production.

The application provides a semiconductor laser element with a topological phonon state layer, comprising, from bottom to top, a substrate, a lower limiting layer, a lower waveguide layer, an active layer, an upper waveguide layer and an upper limiting layer. The application is characterized in that a topological phonon state layer with a multilayer structure is arranged between the lower waveguide layer and the lower limiting layer of the semiconductor laser element, and the saturation electron drift velocity distribution characteristics, the electron affinity energy distribution characteristics and the polarized optical phonon energy distribution characteristics of each layer of the topological phonon state layer are designed, so that the topological quantum state and the topological phase change of the phonon spectrum can be adjusted, the quantum state and the lattice vibration mode can be changed, the Stokes shift loss of the difference between the photon energy of the pump light and the oscillation light can be reduced, and the thermal stress and the temperature quenching problem of the laser can be inhibited.

This invention relates to ONOO ‑ In the field of detection technology, specifically involving an ONOO ‑ Near-infrared fluorescent probe, its preparation method, and its application. This invention constructs a novel fluorescent probe specifically for detecting ONOO. ‑ The ONOO ‑ Near-infrared fluorescent probe for ONOO ‑ It exhibits good reactivity and is capable of specifically imaging endogenous ONOO in living cells or in vivo systems. ‑ Furthermore, it exhibits a large Stokes shift and an emission wavelength of 760 nm, significantly higher than other near-infrared fluorescent probes based on hemicyanine dye structures. In addition, this ONOO... ‑ The near-infrared emission characteristics of near-infrared fluorescent probes enable them to penetrate deeper into tissues and reduce background interference in bioimaging, which is significant for improving imaging sensitivity and accuracy. Based on these characteristics, ONOO... ‑ Near-infrared fluorescent probes can be used for the diagnosis and research of diseases such as atherosclerosis, neurodegenerative diseases, inflammation, and cancer.

The invention discloses a benzothiazole compound as well as a preparation method and application thereof. The compound has a structure as shown in a formula I. The invention provides a series of benzothiazole compounds with novel structures. The compound has an aggregation-induced emission property; the emission reaches near-infrared region emission from conventional short wavelength; the fluorescent probe has the characteristics of large Stokes displacement, long emission wavelength and high fluorescence quantum yield.

The application discloses a beta-galactosidase near-infrared fluorescent probe with a large stokes shift and a preparation method and application thereof. The structure of CPD-gal is shown in formula I. When a 580nm excitation wavelength is used for excitation, CPD-gal has weak fluorescence at 713nm, but can selectively undergo a fluorescence opening reaction with beta-gal. With the increase of the concentration of beta-gal, the fluorescence intensity at 713nm is gradually enhanced, and other interfering ions and species will not interfere with the detection of beta-gal by CPD-gal. Since the emission wavelength is in the near-infrared region and a large stokes shift is generated, the system background fluorescence interference is greatly reduced, and the sensitivity of the detection of beta-gal is improved. Therefore, CPD-gal is suitable for the fluorescence detection of beta-gal with high selectivity and high sensitivity. The probe is successfully applied to the fluorescence imaging of endogenous beta-gal in HeLa cells and SK-OV-3 cells.

The invention relates to the technical field of laser elements, and discloses a laser element with an excitation transfer emission mechanism, which comprises a substrate, a lower limiting layer, a lower wave layer, an active layer, an upper waveguide layer, an electron blocking layer and an upper limiting layer which are sequentially arranged from bottom to top, an Auger auxiliary light emission layer disposed between the active layer and the upper waveguide layer and between the active layer and the lower waveguide layer; wherein the Auger auxiliary light emission layer has a spin exchange Auger type excitation transfer emission mechanism, and the spin exchange transfer rate exceeds 1012s <-1 >. The auxiliary light emission layer with a spin exchange auger type excitation transfer emission mechanism is introduced between the active layer and the waveguide layer of the laser element, so that stokes frequency shift loss can be effectively inhibited, the coupling efficiency from a pumping energy level to a laser energy level is improved, stimulated radiation of the laser element is enhanced, an excitation threshold value is reduced, and the laser element has a good application prospect. Energy loss and waste heat are reduced, temperature distribution uniformity is improved, and the problem of uneven distribution of thermal expansion and thermal stress is relieved.

The application discloses a device and method for detecting energy carrier dissipation behavior in thermal insulation materials, which comprises: a laser emission module for emitting a laser beam; a first filter for separating the laser beam; a supercontinuum beam forming device for processing the second laser beam; a phase delay line for phase delaying the first laser beam; the wavelength range of the supercontinuum beam is wider than that of the pump beam; a second filter for combining the supercontinuum beam and the pump beam, and then irradiating the surface of the sample and being transmitted by the sample; a photodetector collects the transmitted beam; a controller controls the delay time change of the phase delay line once, receives the transmitted beam once, processes each transmitted beam, obtains the corresponding time-resolved broadband spectral coherent anti-Stokes shift, and extracts the longitudinal optical phonon dephasing process of the sample according to the anti-Stokes shift. Multimodal coherent phonon detection of the sample is realized.

The invention belongs to the technical field of photosensitive materials, and particularly relates to an aggregation-induced emission type photosensitizer as well as a preparation method and application thereof. The aggregation-induced emission type photosensitizer provided by the invention has a structure as shown in any one of formulas I-III. The aggregation-induced emission (AIE) photosensitizer has large Stokes shift, can emit light in a near infrared region I (NIR-I), and is beneficial to penetrating deep biological tissues and reducing light damage to the biological tissues; meanwhile, the AIE type photosensitizer has relatively strong I type active oxygen generation capability, and is expected to be used as a photosensitizer for photodynamic therapy. Formula I, Formula II and Formula III.

The invention relates to the field of fluorescent dyes, in particular to a near-infrared fluorescent dye for brain imaging as well as a preparation method and application of the near-infrared fluorescent dye. The near-infrared fluorescent dye for brain imaging has the advantages of novel structure, good biocompatibility, large Stokes shift, high light stability, high fluorescence signal-to-noise ratio and the like; the near-infrared fluorescent dye prepared by the invention is simple in preparation process, mild in reaction condition, short in synthesis path and beneficial to industrial production, and has a wide application prospect.

The application belongs to the technical field of organic electroluminescence, and relates to a N-containing polycyclic aromatic compound and application. The application provides a N-containing polycyclic aromatic compound, which generates a multiple resonance effect through interaction of each N atom in a N-containing fused ring. The multiple resonance effect can reduce the Stokes shift of the molecule, narrow the emission spectrum, and increase the rate of intersystem crossing inversion, so that a high-efficiency, high-color-purity luminescent material is obtained.

The invention discloses a quick response type near-infrared fluorescent probe for detecting Hg < 2 + >, a preparation method of the quick response type near-infrared fluorescent probe and application of the quick response type near-infrared fluorescent probe in actual water samples and biological imaging. The molecular formula of the fluorescent probe is C32H28N2O2S2. On the basis of a strategy of introducing phenothiazine heterocycle to expand xanthene pi conjugation, a large Stokes shift near infrared fluorescent probe for specifically recognizing Hg < 2 + > is constructed. An optical experiment shows that the emission wavelength of the probe for detecting Hg < 2 + > is 780nm, the Stokes shift reaches 166nm, and the probe has the advantages of high sensitivity (the detection limit is 13.4 nM), specificity, quick response (within 1s) and the like when being used for identifying Hg < 2 + >. Due to the excellent photophysical property, the fluorescent probe not only can be used for quantitatively detecting Hg < 2 + > in an environmental water sample, but also can be successfully applied to fluorescence imaging detection of Hg < 2 + > in cells and living bodies.

The application discloses an aggregation-induced emission material with high fluorescence quantum yield and large stokes shift, a preparation method and application thereof, and belongs to the technical field of preparation of the aggregation-induced emission material. The preparation method comprises the following steps: obtaining an intermediate by means of Suzuki-Miyaura coupling reaction of an organic boric acid and bromosalicylaldehyde; and adding the intermediate, sodium metabisulfite and aminophenylthiophenol into an organic solvent, and then performing high-temperature reaction to prepare the aggregation-induced emission material. The aggregation-induced emission material is synthesized by means of a two-step method, can be rapidly and mass-produced, and has the advantages of high fluorescence efficiency, large stokes shift, good stability and the like.

The invention provides a hypochlorous acid fluorescent probe with large Stokes shift and a preparation method and application thereof, and belongs to the technical field of hypochlorous acid fluorescent probes, the hypochlorous acid fluorescent probe is a cationic iridium (III) complex and contains antianions; the Stokes shift of the hypochlorous acid fluorescent probe is larger than or equal to 170 nm, background interference caused by overlapping of exciting light and an emission spectrum is reduced, and the detection signal-to-noise ratio is increased; the hypochlorous acid fluorescent probe disclosed by the invention has the characteristic of quick response to HOCl, and shows relatively high detection sensitivity and excellent selectivity; the hypochlorous acid fluorescent probe can trigger detectable fluorescence signal change after acting with HOCl in cells, so as to realize in-situ detection and imaging of HOCl in cells; the fluorescent probe can be applied to a lambda-carrageenan induced mouse arthritis model, in-vivo fluorescence imaging of endogenous HOCl signals in an inflammation joint area is achieved, and a sensitive and reliable imaging tool is provided for research of inflammation-related disease related HOCl.

The application discloses a degradable NaCeF4-based up / down conversion luminescent material and a preparation method and application thereof, and belongs to the technical field of luminescent materials. 4+ The molar ratio of Ce 3+ , Yb 3+ , Tm 4+ and Zr is (60-80):(18-22):(0.08-0.12):(2-20). The NaCeF4-based up / down conversion luminescent material has good degradability, high up-conversion emission efficiency, and an up-conversion emission Stokes shift increased to the ultraviolet region; the up-conversion luminescent material can simultaneously emit up-conversion luminescence and down-conversion luminescence under 980nm laser irradiation, and is expected to be used as a contrast agent for fluorescence imaging; and the preparation process is simple, environment-friendly and low in cost.

This invention discloses a fluorescent probe that simultaneously distinguishes between hydrogen peroxide and glutathione. The chemical structure of the probe is as follows: This fluorescent probe ingeniously combines a 1,8-naphthalenedimide fluorophore and an isophorone fluorophore, achieving for the first time a dual-channel simultaneous detection of hydrogen peroxide and glutathione. When reacting with glutathione, it emits 500 nm green fluorescence at an excitation wavelength of 380 nm; when reacting with hydrogen peroxide, it emits 680 nm near-infrared fluorescence at an excitation wavelength of 560 nm. The two emissions differ by 180 nm, and the spectra do not interfere with each other, allowing for the selective simultaneous detection of hydrogen peroxide and glutathione. This probe exhibits excellent selectivity for detecting hydrogen peroxide and glutathione, high fluorescence quantum yield, and a large Stokes shift, showing great promise for applications in analytical chemistry, life sciences, and biomedicine.

The application discloses a curcuminoid xanthene compound shown in formula I, a preparation method of the curcuminoid xanthene compound and application of the curcuminoid xanthene compound as a photodiagnosis and treatment agent. The compound has the characteristics of long absorption and emission wavelength, good stability, high phototoxicity, large Stokes shift, good biocompatibility and good cell membrane permeability. Compared with curcumin, the photosensitizer has a longer absorption wavelength, lower dark toxicity and can generate ROS under type-I and type-II synergistic action, and is expected to be applied to PDT in an anaerobic tumor microenvironment.

This invention relates to the field of optical sensing and imaging detection technology, specifically to a triphenylene-oxanthracene derivative, its preparation method, and a fluorescent probe for viscosity detection. The triphenylene-oxanthracene derivative has the general formula shown in Formula I. Compared to Rhodamine B, the synthesized triphenylene-oxanthracene derivative exhibits a larger Stokes shift. Furthermore, the fluorescence intensity of the triphenylene-oxanthracene derivative increases with increasing cell viscosity. In addition, the triphenylene-oxanthracene derivative can be further used to detect mitochondrial viscosity, exhibiting good mitochondrial targeting. In summary, the probe improves the Stokes shift, has a wide optical response pH range, and possesses excellent mitochondrial targeting.

A class of near-infrared (NIR) II fluorescent dyes, their preparation methods, and their anti-tumor applications belong to the field of fine chemical technology. These dyes have a primary absorption band above 800 nanometers, with fluorescence emission peaks covering both NIR I and II, and exhibit a large Stokes shift (up to 160 nanometers in DMF). These dyes can be used for NIR II optical imaging, avoiding defects such as dye self-absorption, autofluorescence, and fluorescence scattering. When excited by NIR light (808 nm), these dyes generate sufficient reactive oxygen species and heat, enabling them to be used in NIR II fluorescence-guided optical therapy. Furthermore, these dyes can target the specific phospholipid cardiolipin in the inner mitochondrial membrane of cells, interfering with the cardiolipin domain, affecting the activity of cardiolipin-binding proteins, and promoting cell apoptosis. These dyes can be used as novel anti-tumor chemotherapy drugs for cancer treatment.

A method of synthesizing carbon quantum dots (CQDs) includes using a dried ground Halodule uninervis seagrass to form a suspension in water, followed by centrifuging and filtering through a filter membrane and a dialysis membrane to form a CQDs solution. The CQDs have a Stokes shift of less than 83.0 nm at an excitation wavelength of 380 to 430 nm.

The invention discloses a preparation method and application of a transition metal ion doped CdSe / ZnS core-shell quantum dot, according to the method, transition metal ions are controllably introduced into a host CdSe / ZnS material forbidden band as a magazine energy level so as to create a new electron energy level, and meanwhile, the number of defect energy levels of the CdSe core quantum dot is remarkably reduced; and a light-emitting mechanism is successfully converted from band-edge exciton recombination to non-radiative transition recombination. And the dependence of the luminescence performance on the physical size of the quantum dot is eliminated. Due to the characteristic, the material has the excellent temperature response characteristic: the material has wide-spectrum and tunable luminescence, huge Stokes shift to eliminate self-absorption, excellent light stability and long fluorescence lifetime, and has the potential of low toxicity. Due to the advantages, the material has a huge application prospect in the fields of biological imaging, fluorescence detection, solid-state illumination and the like.

A color conversion particle includes a core; and a shell that contains the core and absorbs excitation light, and emits light at the core or at an interface between the core and the shell upon receiving the irradiated excitation light. The core is composed of a chalcogenide perovskite, and the core and the shell have band alignment that induces a Stokes shift.

This invention provides a copper-iodine hybrid cluster compound having the structure shown in formula (I). Compared with the prior art, the copper-iodine hybrid cluster compound provided by this invention has excellent thermal stability, high fluorescence quantum yield, large Stokes shift, high solubility, strong absorption in the ultraviolet region, and a simple synthesis method. It meets the requirements of ideal transparent solar concentrator materials and ultraviolet shielding agents, and has broad application prospects in the field of building-integrated photovoltaics. In addition, it can also be applied to anti-counterfeiting coatings, solid-state lighting, X-ray imaging, and other fields.

The invention relates to the field of heavy metal ion detection, in particular to a preparation method and application of a mercury ion colorimetric and ratiometric fluorescent probe based on carbazole. The preparation method of the colorimetric and ratiometric fluorescent probe comprises the following step: carrying out reaction on O-(4-(bromomethyl) phenyl) diphenyl selenophosphonate and (E)-9-ethyl-3-(2-(quinoline-4-yl) vinyl)-9H-carbazole in acetonitrile to generate (E)-1-(4-((diphenyl selenophosphoryloxy) benzyl)-4-(2-(9-ethyl-9H-carbazole-3-yl) vinyl) quinoline bromide. The fluorescent probe has the advantages of simple synthesis route, strong operability, easily available raw materials and low cost, can realize rapid detection of mercury ions by using colorimetric and change of the ratio F528nm / F648nm of fluorescence intensities at two different emission wavelengths, and has the advantages of large Stokes shift, high sensitivity, good selectivity and the like.

The invention discloses a small organic molecule photosensitizer for photodynamic sterilization and a preparation method and application thereof, pyridine cations and malononitrile structures are used as electron withdrawing groups, furan-triphenylamine structures are used as electron donating groups, and the photosensitizer with an electron acceptor-donor structure in molecules is constructed. The reaction conditions required by the synthesis method are mild and simple. The ultraviolet absorption peak of the prepared photosensitizer in water is 580 nm, the emission spectrum peak is 710 nm, and the photosensitizer has large Stokes shift and can efficiently sensitize oxygen in the environment into active oxygen under illumination. According to the photosensitizer prepared by the invention, the electropositivity of pyridine cations is utilized, the photosensitizer is rapidly combined with staphylococcus aureus through electrostatic interaction, and relatively high dark toxicity and phototoxicity are generated to kill bacteria; by utilizing the lipophilicity of a triphenylamine structure, the triphenylamine structure is combined with escherichia coli and pseudomonas aeruginosa through a hydrophobic effect, and two bacteria are killed by utilizing the dark toxicity of the triphenylamine structure and active oxygen generated by illumination, so that the photodynamic sterilization application is successfully realized.

The application relates to the technical field of fluorescent probe, in particular to a fluorescent probe compound for detecting Cu 2+ and a preparation method and application method thereof. The application provides a fluorescent probe compound DM-2 for detecting Cu 2+ and a preparation method and application method thereof; the probe DM-2 emits weak green fluorescence in a weak alkaline HEPES buffer solution; after Cu 2+ is added, the fluorescence intensity at 600 nm is rapidly increased, and reaches stability in 10 min; the main advantages of the probe are as follows: first, the probe DM-2 has the properties of a ratio type probe and has a large stokes shift; second, after the probe reacts with Cu 2+ , the solution color changes from colorless to yellow, and the fluorescence color changes from green to orange, so that visual detection and analysis of Cu 2+ can be realized; and third, the fluorescent probe has simple synthesis steps, high yield and good stability.

This invention proposes a gallium nitride-based semiconductor laser, comprising, from bottom to top, a substrate, a lower confinement layer, a lower waveguide layer, an active layer, an upper waveguide layer, and an upper confinement layer. This invention incorporates a multi-layered, multi-vacancy electron-phonon modulation layer within the semiconductor laser element, defining the electron affinity distribution and polarization optical phonon energy distribution characteristics of each multi-vacancy electron-phonon modulation layer. This forms single-vacancy, vacancy cluster, and multi-vacancy modulated electron-phonon structures, localizing electron-phonons between the lower confinement layer and the lower waveguide layer. This reduces the Stokes shift caused by the photon energy difference between the pump light and the oscillating light, reduces heat loss from phonon vibration and phonon transport, improves the heat dissipation of the laser element, mitigates interlayer thermal mismatch, suppresses the thermal lensing effect and stress birefringence effect of the laser, improves laser beam distortion and depolarization, and enhances the laser beam quality factor.

The application provides an organic-inorganic hybrid lead-based halide perovskite material and a preparation method and application thereof. The organic-inorganic hybrid lead-based halide perovskite material has a one-dimensional face-sharing perovskite structure or a quasi-one-dimensional face-sharing perovskite structure, and a chemical general formula of the organic-inorganic hybrid lead-based halide perovskite material is APbX3, A includes an alkyl-substituted triphenylphosphine cation, and X is at least one of halogen elements. The organic-inorganic hybrid lead-based halide perovskite material provided by the application has a one-dimensional or quasi-one-dimensional face-sharing perovskite structure under a specific component composition, can simultaneously realize material properties of no self-absorption and nanosecond-level ultrafast self-trapped exciton emission, has a large Stokes shift, breaks through the traditional STE ''slow decay'' fixed limit, has a high X-ray absorption capacity, has low detection limit and high spatial resolution, and is suitable for low-dose and high-resolution imaging.

This invention provides a calcium-based MOF crystal material with photoelectric effect, its preparation method, and its applications. The material uses L-malic acid (L-2-hydroxysuccinic acid) as the organic ligand and calcium ions as the metal center, forming a three-dimensional network structure with an MBR topology. The calcium-based MOF crystal material of this invention exhibits photoelectric effect, displaying a main peak at λex = 440 nm. With a fixed λ_ex = 440 nm, the emission spectrum shows a strong sharp peak at λ_em = 550 nm, with a Stokes shift of Δλ = 125 nm. The excited state exhibits significant lattice relaxation, making it suitable as a fluorescent matrix material for preparing photoexcited materials and devices. The calcium-based MOF crystal material of this invention is prepared using aloe vera as a raw material. The organic components in aloe vera participate in MOF formation as organic ligands. The preparation method is simple, the preparation conditions are mild, and production costs are reduced.