507 results about "Chemical groups" patented technology

An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirror formed on a sensor surface of the substrate, a plasmon resonance particle layer disposed over the mirror, and an optically transparent dielectric layer about 2-40 nm thick separating the mirror and particle layer. The particle layer is composed of a periodic array of plasmon resonance particles having (i) a coating effective to binding analyte molecules, (ii) substantially uniform particle sizes and shapes in a selected size range between 50-200 nm (ii) a regular periodic particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting analyte with an amplification factor of up to 10¹²-10¹⁴, allowing detection of single analyte molecules.

This invention features permeability enhancer molecules, and methods, to increase membrane permeability of various molecules, such as nucleic acids, polynucleotides, oligonucleotides, enzymatic nucleic acid molecules, antisense nucleic acid molecules, 2-5A antisense chimeras, triplex forming oligonucleotides, decoy RNAs, dsRNAs, siRNAs, aptamers, or antisense nucleic acids containing nucleic acid cleaving chemical groups, peptides, polypeptides, proteins, carbohydrates, steroids, metals and small molecules, thereby facilitating cellular uptake of such molecules.

Methods of producing substrates having selected active chemical regions by employing elements of the substrates in assisting the localization of active chemical groups in desired regions of the substrate. The methods may include optical, chemical and/or mechanical processes for the deposition, removal, activation and/or deactivation of chemical groups in selected regions of the substrate to provide selective active regions of the substrate.

The present invention features a new and useful magnetic device and methods of its use for isolation, enrichment, and purification of cells, proteins, DNA, and other molecules. In general the device includes magnetic regions or obstacles to which magnetic particles can bind. The chemical groups, i.e., capture moieties, on the surface of the magnetic particles may then be used to bind particles, e.g., cells, or molecules of interest from complex samples, and the bound species may then be selectively released for downstream collection or further analysis.

An elastomeric gel-filled prosthetic implant having a shell made of a single gel barrier layer. The barrier layer is formed of a homogeneous silicone elastomer capable of sterically retarding permeation of the silicone gel through the shell and having a bleed rate that is less than about 40% of the bleed rate of current shells which use a sandwiched construction with an internal barrier layer. Further, the barrier layer shell is made of a material that exhibits a wet strength that is comparable to or greater than current shells. The silicone elastomer may be a polydimethyl siloxane, and the substituted chemical group is a diphenyl group with a minimum mole percent of at least 13%. The implant may be designed for breast reconstruction or augmentation such that the shell is accordingly shaped. The shell wall thickness is at least 0.254 mm (0.010 inches), and desirably about 0.456 mm (0.018 inches). The implant shell may be made by dip-forming, spray-forming, or rotational molding. The exterior may be smooth or textured.

Processes for biogenic production of a hydrogen-carbon-containing fluid from a hydrocarbon containing formation are described. The processes may include providing in the formation an anaerobic microorganism consortium containing one or more enzymes to activate a starting hydrocarbon by an addition of a chemical group to the hydrocarbon. The processes may further include converting the activated hydrocarbon into the hydrogen-carbon-containing fluid through one or more intermediate hydrocarbons, and recovering the hydrogen-carbon-containing fluid from the formation.

Pharmaceutical, chemical and biological agents containing a reversible disulfide linker are described. These agents can also be covalently bound or contained in delivery vehicles for delivering the agents to desired targets or areas. Also described are delivery vehicles which contain an agent having a reversible disulfide linker and to vehicles that are covalently linked to the agent containing a reversible disulfide linker. The modifications described herein can modify properties of the agents and vehicles, thereby providing desired solubility, stability, hydrophobicity and targeting while the reversibility of the linker can leave the agent to which it is attached free from residual chemical groups after being reduced.

The present invention is directed to a method for removing cytokines and/or pathogens from blood or blood serum (blood) by contacting the blood with a solid, essentially non micro-porous substrate which has been surface treated with heparin, heparan sulfate and/or other molecules or chemical groups (the adsorbent media or media) having a binding affinity for the cytokine or pathogen(s) to be removed (the adsorbates), and wherein the size of the interstitial channels within said media is balanced with the amount of media surface area and the surface concentration of binding sites on the media in order to provide adequate adsorptive capacity while also allowing relatively high flow rates of blood through the adsorbent media.

Modified fillers are described which have adsorbed and/or attached chemical groups, such as a triazole and/or pyrazole thereon. Other modified fillers are also described. Elastomeric compositions containing the modified filler are further described, as well as methods to improve hysteresis and/or abrasion resistance in elastomeric compositions using the modified fillers of the present invention.

Functionalized polymers are mixed with pesticides to form semi-stable complexes with desirable field properties: reduced leaching in soil, improved leaf retention (rainfastness), selective unloading to roots and convenient packaging and application. Pesticides that may be so complexed include herbicides, insecticides (including compounds controlling non-insect arthropods and nematodes), bacteriocides, rodenticides, and fungicides. Polymers with which they may be complexed include derivatives of carbohydrates, amides, imines, alkanes, vinyls, styrenes or glycols. The polymers may be functionalized with chemical groups that exhibit ionic (amines, carboxyls), hydrophobic, complexing (e.g. metal chelating) and ligand binding interactions. The variously functionalized polymers may be mixed, grafted, or fused to obtain optimal properties. The polymer/pesticide formulations may be applied as granules, as suspensions or solutions in sprays, as foams, or as coats for seeds and fertilizers. The formulations may be applied to foliage, soil, irrigation water, construction materials (plastics, wood), seeding materials, grains, and buildings.

This invention provides methods for producing a polymer particle which contains unusually high negative charges on the surface of the particle. Preferably, the polymer is pharmaceutically acceptable. The negative charges can be conferred by chemical groups such as carboxyl, sulfonate, nitrate, fluorate, chloride, iodide, persulfate, and many others, with carboxyl group being preferred. The invention also provides polymer particle produced by the methods of the invention.

The invention relates to an organic semiconductor material containing naphthalene [1, 2-c: 5, 6-c] di [1, 2, 5] thiadiazole and application thereof, wherein the organic semiconductor material is prepared by reacting the halogenated derivatives with the monomer containing an aromatic group structure under the metal catalyst, wherein the halogenated derivatives are obtained by halogenating the naphthalene [1, 2-c: 5, 6-c] di [1, 2, 5] thiadiazole; the aromatic group is connected with a naphthalene [1, 2-c:5, 6-c] di [1, 2, 5] thiadiazole unit in a conjugate manner. The organic semiconductor material is characterized by containing 3, 7 substituted decorative[1, 2-c: 5, 6-c] di [1, 2, 5] thiadiazole chemical groups; as the naphthalene [1, 2-c:5, 6-c] di [1, 2, 5] thiadiazole has excellent electron-withdrawing ability and planarity, the organic semiconductor material can excellently adjust the photoelectric property, has excellent photoelectric performance, and is applied to the field of organic photoelectric components.

A color image is digitally printed onto an intermediate transfer medium. The image is subsequently transferred from the intermediate transfer medium to a final substrate, which may be a cellulosic textile, such as cotton. Bonding of the color images is provided by the reaction between compounds selected from each of two chemical groups contained in the intermediate transfer medium. The first groups comprises compounds with functional groups capable of reacting with active hydrogen, such as isocyanate or epoxy groups. The second group comprises compounds with functional groups containing active hydrogen, or compounds with functional groups containing active hydrogen after a conversion process. The functional groups of one or both reactive chemical groups may be protected either by blocking with internal or external blocking agents or by a physical barrier such as encapsulating agents. The blocking agents are removed by the application of energy, such as heat, during the transfer of the image from the intermediate transfer medium to the final substrate. The intermediate transfer medium may be comprised of additional components which may be combined with either or both of the above two chemical groups, or applied as separate layers. Examples of such components are a thermally expandable material, an exothermic chemical, a release agent, and/or absorbent material. Transferred images so produced have a soft hand, particularly when applied to a textile, and excellent fade and abrasion resistance.

The invention discloses an aqueous acrylic emulsion, an aqueous adhesive for plastic-plastic composite materials and a preparation method thereof, and belongs to the field of preparation of adhesive. The acrylic emulsion is polymerized from 30-50 wt% of acrylic acid hard monomer, 40-60 wt% of acrylic acid soft monomer and 5-10 wt% of acrylic acid functional monomer under the action of water, an emulsifying agent, an initiator, a buffering agent and a pH regulator. The invention also provides an aqueous adhesive and a preparation method thereof. The molecule segment of the film forming matter (acrylate copolymer) in the aqueous acrylic emulsion has various chemical groups, such as -OH, -COOH, -NH and the like; and the chemical groups can form various chemical bonds and hydrogen bonding acting force, and thereby having favorable adhering force for various composite substrates (plastic films, aluminum plating films, metal foils and the like). By properly matching the soft monomer and the hard monomer and adopting the corresponding functional monomer to participate in the copolymerization, the invention enhances the adhesive affinity to the plastic films with low surface tension, thereby enhancing the wetting property of the adhesive on the surface of the plastic films and the combined strength.

The invention discloses an aqueous acrylic emulsion, an aqueous adhesive for pearlized film composite materials and a preparation method thereof, and belongs to the field of preparation of adhesive. The acrylic emulsion is polymerized from 20-40 wt% of acrylic acid hard monomer and 55-70 wt% of acrylic acid soft monomer and 1-5 wt% of acrylic acid functional monomer under the action of water, an emulsifying agent, an initiator, a buffering agent and a pH regulator. The invention also provides an aqueous adhesive and a preparation method thereof. The molecule segment of the film forming matter (acrylate copolymer) in the aqueous acrylic emulsion has various chemical groups, such as -OH, -COOH, -NH and the like; and the chemical groups can form various chemical bonds and hydrogen bonding acting force, and thereby having favorable adhering force for various composite substrates (plastic films, aluminum plating films, metal foils and the like). The polymer obtained by polymerization has higher molecular weight, lower coating viscosity and favorable levelling property; and thus, the polymer has high shear strength and initial strength and can achieve the best bonding strength without curing for a long time.

The invention provides an organic semiconductor material containing 6-R group-[1, 2, 5] thiazole [3, 4-g] benzotriazole and an application thereof. Diazosulfide is used as parent, benzotriazole derivatives are formed by reduction and ring closure of nitrated diazosulfide, and finally, a halogenated 6-R group-[1, 2, 5] thiazole [3, 4-g] benzotriazole monomer is synthesized by performing alkylation reaction on an H of an N atom; and the monomer is reacted with a monomer containing an aromatic group under effect of metal catalyst to prepare the organic semiconductor material. Positions 1, 2, 5 and 6 of a benzene ring of the organic semiconductor material are respectively connected with alkyl triazole and thiazole, the two kinds of chemical groups have excellent electron attracting performance, and a formed ternary condensed ring has better planarity and conjugated bonds, and also has good dissolubility. The organic semiconductor material provided by the invention can be used as an active layer having application foreground to be applied in organic photoelectric devices.

The invention is related to a FVIII analogue which has a circulation time in the blood stream before activation of at least about two times of that of native FVIII and a week after injection to a patient retains at least about 5% of the FVIII activity compared to the initial activity peak value reached after injection. The claimed FVIII analogues comprise a targeted disruption of one or more of the clearance sites in the FVIII molecule by introduction of at least one N-glycosylation site or by introduction of at least one Cys residue within or spatially close to the clearance site in the A2 domain or a combination thereof. The inserted cysteine residues may be further modified by conjugation with a chemical group increasing the molecular weight of the FVIII analogue.