325results about How to "Produced in advance" patented technology

The present invention provides a novel aromatic amine derivative having a specific structure and an organic electroluminescence device in which an organic thin film layer comprising a single layer or plural layers including at least a light emitting layer is interposed between a cathode and an anode, wherein at least one layer in the above organic thin film layer, particularly a hole transporting layer contains the aromatic amine derivative described above in the form of a single component or a mixed component. Use of the aromatic amine derivative described above materialize an organic electroluminescence device which reduces a driving voltage and makes molecules less liable to be crystallized and which enhances a yield in producing the organic EL device and has a long lifetime.

An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirror formed on a sensor surface of the substrate, a plasmon resonance particle layer disposed over the mirror, and an optically transparent dielectric layer about 2-40 nm thick separating the mirror and particle layer. The particle layer is composed of a periodic array of plasmon resonance particles having (i) a coating effective to binding analyte molecules, (ii) substantially uniform particle sizes and shapes in a selected size range between 50-200 nm (ii) a regular periodic particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting analyte with an amplification factor of up to 1012-1014, allowing detection of single analyte molecules.

A hybrid-vehicle drive method and system includes an internal combustion engine that includes an output shaft, a first electric motor / generator connected to the output shaft of the internal combustion engine via a power distribution mechanism, a wheel drive shaft connected to the output shaft of the internal combustion engine via the power distribution mechanism, a second electric motor / generator connected to the wheel drive shaft, and a transmission located on at least one of the wheel drive shaft and a connecting portion of the second electric motor / generator with the wheel drive shaft.

Methylotrophic yeasts are useful hosts for the production of commercially valuable recombinant proteins. However, the development of large-scale cultures of recombinant methylotrophic yeasts has been hindered by the formation of precipitation in culture media. A new soluble minimal medium overcomes this problem. Moreover, new feeding schemes provide cultures of high biomass, which produce biologically active recombinant protein.

L-Arginine is produced by culturing a coryneform bacterium in which an arginine repressor involved in L-arginine biosynthesis is deleted by disrupting a gene coding for the repressor, and which has L-arginine producing ability in a medium to produce and accumulate L-arginine in the medium, and collecting the L-arginine from the medium.

An optical sensor and method for use with a visible-light laser excitation beam and a Raman spectroscopy detector, for detecting the presence chemical groups in an analyte applied to the sensor are disclosed. The sensor includes a substrate, a plasmon resonance mirror formed on a sensor surface of the substrate, a plasmon resonance particle layer disposed over the mirror, and an optically transparent dielectric layer about 2-40 nm thick separating the mirror and particle layer. The particle layer is composed of a periodic array of plasmon resonance particles having (i) a coating effective to binding analyte molecules, (ii) substantially uniform particle sizes and shapes in a selected size range between 50-200 nm (ii) a regular periodic particle-to-particle spacing less than the wavelength of the laser excitation beam. The device is capable of detecting analyte with an amplification factor of up to 1012-1014, allowing detection of single analyte molecules.

A method for determining a desired location at which to apply a neural therapy. An array of electrodes is positioned proximal to neural tissue. A stimulus is applied from the array which evokes a neural compound action potential response in the neural tissue proximal to the array. A plurality of electrodes of the array simultaneously obtain respective measurements of the neural compound action potential response. From the measurements of the neural compound action potential response a desired location for a neural therapy is determined.

The present invention is generally provides recombinant microorganisms comprising engineered metabolic pathways capable of producing C3-C5 alcohols under aerobic and anaerobic conditions. The invention further provides ketol-acid reductoisomerase enzymes which have been mutated or modified to increase their NADH-dependent activity or to switch the cofactor preference from NADPH to NADH and are expressed in the modified microorganisms. In addition, the invention provides isobutyraldehyde dehydrogenase enzymes expressed in modified microorganisms. Also provided are methods of producing beneficial metabolites under aerobic and anaerobic conditions by contacting a suitable substrate with the modified microorganisms of the present invention.

Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.

An optical fiber, comprising: (i) a rare earth doped silica based elongated core with a first refractive index (n1) with an aspect ratio of 1:5 to 1; (ii) a silica based moat abutting and at least substantially surrounding the core, the moat having a refractive index n2, wherein n2<n1; (iii) a silica based inner cladding surrounding the moat, the inner cladding having a third refractive index (n3), wherein n1>n3; and n3>n2; (iv) a silica based outer cladding surrounding said inner cladding, the outer cladding having a fourth refractive index (n4), such that n4<n3; the optical fiber exhibits single polarization at the operating wavelength band.

The present invention relates to methods of producing modified fatty acids comprising a functional group which is a hydroxyl group, an epoxy group, an acetylenic group or a conjugated double bond. For example, seeds, seedoil and methods of making seedoil are provided wherein at least 23% (mol %) of the fatty acid content of the seed or seedoil comprises the functional group. Also provided are novel polypeptides, and polynucleotides thereof, which can be used to produce the modified fatty acids, particularly in transgenic plants and cells suitable for fermentation.

An optical fiber including: (i) a silica based, rare earth doped core having a first index of refraction n1; and (ii) at least one silica based cladding surrounding the core and having a second index of refraction n2, such that n1>n2, said cladding having a plurality of stress rods and a plurality of air holes extending longitudinally through the length of said optical fiber; wherein said optical fiber supports a single polarization mode or poses-polarization maintaining properties within the operating wavelength range.

A filter rod making machine comprises a plurality of feed wheels (50) for feeding filter elements (fA, fC) at intervals; a conveyor (18) for receiving the filter elements (fA, fC) from the feed wheels (50) and forming an element stream in which the filter elements (fA) and the filter element (fC) are arranged alternately; a wrapping apparatus (62) for forming the element stream into a composite element column (CE) in which the filter elements (fA, fC) are in close contact with each other, and then into a composite element rod (ER) by wrapping the composite element column (CE) in a paper web (W); a cutting apparatus (92) for cutting the composite element rod (ER) into individual filter rods (FR); and a phase change apparatus (112) for adjusting the rotation phase of the feed wheel (50) on the basis of information on the filter rod (FR) cut.

Compositions containing polymeric micro- and nanoparticles with non-spherical shapes and methods for making and using such particles are described herein. The particles have a size range from an average diameter of about Compositions containing polymeric micro- and nanoparticles with non-spherical shapes and methods for making and using such particles are described herein. The particles have one or more dimensions ranging from about 5 nm to about 100 μm, preferably about 100 nm to 10 μm. The particles can have any of a wide variety of non-spherical shapes. The particles are generally formed by manipulation of spherical particles embedded in a polymeric film. A wide variety of resulting shapes can be made. The resulting shape is a function of whether the films are manipulated in a first and / or second dimension, and the processes used to liquefy the microparticles. Variations of the method of manufacture may be used to generate particles having the desired shapes in large, reproducible quantities. The resulting non-spherical shaped particles can be used to alter uptake by phagocytic cells and thereby clearance by the reticuloendothelial system.

Culture media comprising manganese and methods of culturing cells to improve sialylation and glycosylation of glycoproteins are provided.

A rotary cutting saw comprising: a base disk; and a plurality of abrasive segments which are bonded to an outer circumferential surface of the base disk so as to be spaced apart from each other in a circumferential direction of the base disk. The base disk has a plurality of slits which are formed in the outer circumferential surface of the base disk so as to be located between the abrasive segments in the circumferential direction. Each of the slits is defined by a pair of side surfaces opposed to each other in the circumferential direction, and a part-cylindrical surface defining a part of a cylinder whose axis is parallel to the axial direction. The part-cylindrical surface has a circumferential width which is larger than a circumferential distance between the radially inner end portions of the side surfaces. The part-cylindrical surface is smoothly connected to one of the side surfaces without a stepped portion therebetween.

The present invention relates to a process for the production of a composition wherein the process comprises pre-treating cellulosic fibers by mechanical, chemical and / or enzymatic treatment, mixing the pre-treated cellulosic fibers with pigments forming a dispersion and dispersing the dispersion of pre-treated cellulosic fibers and pigments whereby a composition comprising microfibrillated cellulose is formed. The invention further relates to a composition produced according to the process.

Methods which can be applied during the epitaxial growth of semiconductor structures and layers of III-nitride materials so that the qualities of successive layers are successively improved. An intermediate epitaxial layer is grown on an initial surface so that growth pits form at surface dislocations present in the initial surface. A following layer is then grown on the intermediate layer according to the known phenomena of epitaxial lateral overgrowth so it extends laterally and encloses at least the agglomerations of intersecting growth pits. Preferably, prior to growing the following layer, a discontinuous film of a dielectric material is deposited so that the dielectric material deposits discontinuously so as to reduce the number of dislocations in the laterally growing material. The methods of the invention can be performed multiple times to the same structure. Also, semiconductor structures fabricated by these methods.

The present invention relates to a process for the production of a composition wherein the process comprises pre-treating cellulosic fibers by mechanical, chemical and / or enzymatic treatment, mixing the pre-treated cellulosic fibers with pigments forming a dispersion and dispersing the dispersion of pre-treated cellulosic fibers and pigments whereby a composition comprising microfibrillated cellulose is formed. The invention further relates to a composition produced according to the process.

The present invention concerns improved methods and compositions for producing a Neublastin polypeptide as well as local delivery of Neublastin to specific regions of the nervous system including the central nervous system and the eye for example by gene therapy. The invention also concerns Neublastin expression constructs which do not encode a pro-region of a Neublastin polypeptide, which expression construct result in increased secretion of bioactive Neublastin. The invention includes the delivery of Neublastin from transduced or transfected cells encapsulated into a macrocapsule with a semipermeable membrane. The invention further concerns mammalian cells capable of producing Neublastin in increased amounts.

The invention disclosed provides a method for inducing nucleation in a polymer by subjecting the polymer containing dissolved gas to an external stress generated, for example, by applying hydrostatic or mechanical pressure. The applied stress restricts the bubble growth so that the foamed materials have small cells and high cell density. Such microcellular foams can be produced over a wide low temperature range, i.e. from the temperature at which the polymer is conditioned with the blowing agent up to about the glass transition temperature of the polymer-blowing agent system. Stress induced nucleation can also be conducted at higher temperatures i.e. up to about the Tg of the neat polymer, leading to foams with larger cells. A variety of homogeneous and heterogeneous foams can be produced by this technique.

A method and apparatus for producing a chilled or partially frozen beverage is provided. The system includes a beverage hopper (32) a chilling unit (44), a rotatable mixing member (38), a sensing member (230) for detecting an occurrence of a rotation reversal condition, a controller for generating a rotation reversal signal in response to the sensing member, and a drive motor (36) coupled to the mixing member for rotating the mixing member in a first direction and a second, reverse direction in response to a rotation reverse signal.

The object of the present invention is to provide a high quality polyester resin having high productivity, stability and safety, a catalyst for polyester production with high catalytic activity, a method for producing the polyester resin with the catalyst, a polyester resin obtained with the catalyst, and a hollow molded container comprising the polyester resin. The polyester resin of the present invention satisfies specific parameters regarding polymerizability, stability, and metal content. The catalyst for polyester production satisfies specific parameters. The catalyst particularly preferably comprises: (a) a solid titanium-containing compound which has a maximum solubility in ethylene glycol of 1,000 ppm or more in terms of converted titanium amount when dissolved in ethylene glycol with heating at 150° C., and which comprises titanium, oxygen, carbon, and hydrogen, and optionally alkali metal, and has a Ti—O—C bond; and (b) an alkali metal compound, the molar ratio of the alkali metal atoms to the titanium atom in the catalyst being in the range of 20 / 1 to 0.1 / 1.

A lubricant supported electric motor includes a static member and a movable member movably disposed within the static member to define a gap therebetween. The static member may be configured as a stator and the movable member may be configured as a rotor. The movable member may also be configured to move relative to the static member. The static member and movable member are configured to exert an electromagnetic force therebetween and convert electrical energy into mechanical energy and move the movable member. A lubricant is disposed in the gap between the static member and the movable member to support the movable member relative to the static member.

In an apparatus for the fibre-sorting or fibre-selection of fibre material which is supplied by means of a supply device to a fibre-sorting device, mechanical means are present which generate a combing action to remove non-clamped constituents such as short fibres. Downstream of the supply device there are arranged at least two rotatably mounted rollers with clamping devices for the fibre bundles, and the supply device comprises a feed unit, which feed unit comprises a feed roller and at least one feed tray defining a nip between said feed roller and said feed tray, and the retaining force in the nip optimally retains the short fibres completely or substantially completely in the nip during separation of a fibre bundle by said clamping devices.

In an apparatus for the fibre-sorting or fibre-selection of fibre material which is supplied by means of supply means to a fibre-sorting device, at least one mechanical device is present which generate a combing action to remove non-clamped constituents such as short fibres. To enable productivity to be substantially increased in a simple manner and an improved combed sliver to be obtained, downstream of the supply device there are arranged at least first and second rotatably mounted rollers with clamping devices for the fibre bundles, and the apparatus further comprises at least two supply devices and / or at least one further high-speed roller and / or at least two take-off devices.

In an apparatus for the fibre-sorting or fibre-selection of a fibre bundle comprising textile fibres, especially for combing, which is supplied to a fibre-sorting device, especially a combing device, having clamping devices which clamp the fibre bundle at a distance from its free end, which is combed to remove non-clamped constituents, the clamping devices each comprise two clamping jaws. To increase productivity and to enable an improved combed sliver to be obtained, downstream of the supply device there are arranged at least two rotatably mounted rollers rotating rapidly without interruption, the clamping devices being spaced apart in the region of the periphery of the rollers, and each clamping device comprising at least one nipper part which is at least partially resilient. The clamping jaws may have a high coefficient of friction in the region of their clamping surfaces.

In an apparatus for the fibre-sorting or fibre-selection of a fibre bundle comprising textile fibres, especially for combing, fibre is supplied by a supply device to a fibre-sorting device, especially a combing device. Clamping devices clamp the fibre bundle at a distance from its free end, and a mechanical device combs the free end to loosen and remove non-clamped constituents, for example, short fibres, neps, dust and the like. To increase productivity and obtain an improved combed sliver, downstream of the supply device there are at least two rotatably mounted rollers rotating rapidly without interruption, which are provided with the clamping devices, and measured value sensors for detecting values relating to the fibres or machine settings are connected to a control and regulation device, which is arranged to effect actions in dependence on the measured values.