228 results about "Excitation beam" patented technology

The invention provides a non-contact polarized light acoustic detection device and method for identifying the quality of traditional Chinese medicinal materials. According to the device, a traditional Chinese medicinal material sample is excited by using a polarization-modulated pulse excitation light beam, and refractive index change caused by photoacoustic initial pressure generated when the sample absorbs excitation light pulse energy is measured by using a continuous wave detection light beam confocal with the excitation light beam. By detecting the reflection component of the detection light beam, the device can obtain anisotropic optical absorption information of the traditional Chinese medicinal materials. The traditional Chinese medicinal material polarized light acoustic image and the anisotropic characteristic information thereof are obtained by using the non-contact polarized light acoustic detection device and method, the quality of the traditional Chinese medicinal material can be identified, the traditional Chinese medicinal material sample is not damaged in the whole process, and non-contact in-situ detection is realized.

The invention discloses an alveolar bone noninvasive detection method based on a spatial offset Raman spectrum technology. The method comprises the following steps: S1, selecting a first near-infrared excitation wavelength and a second near-infrared excitation wavelength to form a multi-wavelength tunable excitation light beam; s2, synchronously acquiring a first group of original Raman spectrum signals under a plurality of spatial offset distances; s3, acquiring a second group of original Raman spectrum signals by using an acousto-optic composite modulation Raman enhancement mechanism; s4, inputting the soft tissue optical parameter set into a joint inversion equation; s5, obtaining a deep alveolar bone Raman characteristic spectrum data set; s6, training an alveolar bone tissue health recognition model; and S7, based on the alveolar bone tissue health recognition model, performing health state judgment on the deep alveolar bone Raman characteristic spectrum data set acquired in real time, and generating an alveolar bone health assessment result. The early screening and dynamic monitoring capabilities of alveolar bone diseases are greatly improved, and the clinical working efficiency of doctors and the doctor-seeing experience of patients are remarkably optimized.

The invention discloses a multi-gas synchronous detection device and method based on dual-frequency wavelength modulation and demodulation, and relates to the field of gas detection, the device comprises a light source module, a photoacoustic signal detection module and a data processing module; wherein the light source module outputs an excitation light beam and irradiates the excitation light beam into a gas chamber of the photoacoustic signal detection module; the excitation light beam is a light beam modulated by a sawtooth wave signal and two sine waves with different frequencies; the photoacoustic signal detection module receives photoacoustic signals generated after each gas to be detected in the gas chamber interacts with the excitation light beam and converts the photoacoustic signals into piezoelectric signals; and the data processing module performs secondary harmonic demodulation on the piezoelectric signal to obtain demodulated secondary harmonic data, and further inverts the concentration of the gas to be detected. According to the invention, two sine wave signals with different frequencies are superposed on the basis of a sawtooth wave signal, the frequency distribution of a modulation signal is expanded, and the concentration of gas adjacent to various absorption lines can be accurately detected at the same time.

The invention provides a sea surface oil film thickness measuring method based on optimized laser-induced fluorescence spectrum wave bands, and belongs to the technical field of spectral analysis. The method comprises the following steps: emitting an excitation light beam to a to-be-measured sea surface oil film by using a laser, and exciting the oil film to generate a fluorescence signal; receiving the fluorescence signal based on a spectrum acquisition device, and obtaining fluorescence spectrum data of the oil film; selecting a characteristic wave band from the fluorescence spectrum data through a sparse partial least square model, and predicting the thickness of the sea surface oil film based on the characteristic wave band in combination with Lasso regression; meanwhile, the selection of characteristic wave bands is optimized by using a hedera helix algorithm. According to the method, the characteristic wave band of oil film detection is selected through the sparse partial least square model, the oil film measurement characteristic wave band is efficiently and accurately obtained, full-wave band collection is avoided, and the detection efficiency is improved; and in combination with the hedera helix optimized sparse partial least square model, the accuracy of characteristic wave band selection and the generalization of the model are further improved, and the precision and efficiency of oil film thickness measurement are remarkably improved.

An illuminating system includes a light source module and a light homogenizing element. The light source module includes at least one sub-light source module, and each sub-light source module includes a light-emitting element, a wavelength conversion element, a light-splitting element, a reflective element and a light guide element. The reflective element is configured to reflect the exited light beam converted by the wavelength conversion element to the light guide element. The light guide element includes a light incident surface, a reflective surface and a light exit surface. By designing the angle between the light incident surface of the light guide element and the light exit surface to be an acute angle, combined with the deflection configuration of the reflective element, the excited beam may be transmitted along different transmission paths without optical loss.

A rapid optical tissue scanner includes: a light source unit for irradiating a sample with a light source beam; a cylindrical lens for transforming the light source beam into a light sheet; a sample mounting unit on which the sample is mounted; an objective lens disposed between the cylindrical lens and the sample mounting unit to irradiate the sample with the light source beam transformed into a light sheet; and a photographing unit for receiving an excitation beam, which is obtained by excitation from the sample, from the objective lens and photographing image information of the sample.

The invention relates to a single-objective isotropic three-dimensional super-resolution imaging method, which comprises the following steps of: outputting a linear polarization excitation light beam through a picosecond pulse laser, and outputting a linear polarization loss light beam through a nanosecond pulse laser, adjusting the polarization direction and power of the excitation light beam and the loss light beam by using a half-wave plate and a polarization beam splitter, enabling the loss light beam to enter a spatial light modulator, modulating a light field by loading a preset phase diagram, generating three focuses with different topological charges, axial positions and energy distribution, and outputting the three focuses. The high-order vortex phase retarder is used for carrying out polarization state modulation on the focus and separating loss light beams with different polarization components, the imaging resolution ratio smaller than 100 nm in the transverse direction and the axial direction is achieved, the transverse resolution ratio is similar to the axial resolution ratio, the three-dimensional real structure of an object can be accurately reflected when three-dimensional super-resolution imaging is carried out, and the imaging precision is improved. The imaging resolution is in direct proportion to the loss light intensity, and the higher the loss light intensity is, the higher the three-dimensional imaging resolution is.

The invention discloses a miniaturized laser differential confocal Raman-LIBS (laser-induced breakdown spectroscopy) microscopic imaging method and device, and belongs to the technical field of microscopic spectral imaging. The device comprises a double-laser light source system for generating excitation light beams, an optical filter for separating spectral signals, a double-two-dimensional galvanometer light beam scanning system, a microscope objective, an axial scanning system, a differential confocal microscopic detection system, a mixed spectrum detection system and a computer control and display system. A double-two-dimensional micromirror scanning technology and a differential confocal microscopy technology are combined to carry out three-dimensional scanning on a sample, so that high-spatial-resolution detection of the geometrical morphology of the sample is realized; a same-light-path continuous laser and a pulse laser are respectively used as excitation light sources of Raman spectrum and laser-induced breakdown spectrum, and detection is carried out at a focal point on the surface of a sample, so that high-precision spectral information detection on the surface of the sample is realized. The sensor has the advantages of high sensitivity, multiple information, miniaturization, simple structure, wide applicability and the like, and is particularly suitable for the fields of environmental science, biomedicine, geological exploration and the like.

According to the stimulated radiation wafer detection device provided by the invention, the excitation light beam generated by the excitation light source is collimated, dodging and shape-modulated by the first illumination lens group to form a uniform shaping light beam; a convergent light beam generated by converging the shaped light beam through the second illuminating lens group can form an emergent light beam after passing through the light beam separation element and the objective lens, the emergent light beam irradiates the surface of a wafer to excite and generate fluorescent light, the objective lens receives the fluorescent light and transmits the fluorescent light to the light beam separation element, and the fluorescent light is transmitted by the light beam separation element and transmitted to the camera; the camera captures fluorescence and carries out fluorescence imaging so as to realize wafer detection. The light source energy can be efficiently utilized by adopting the shaping light beam for illumination; meanwhile, one-time or multi-time convergence of converged light beams in an illumination light path can be avoided, heat energy is prevented from being generated in a concentrated mode, obvious heat influence caused by high-energy convergence is avoided, deformation of surrounding optical elements or structural elements due to heat influence is avoided, the illumination service life is prolonged, and the illumination effect is improved.

The invention discloses a non-contact optical coherence elastography endoscope device and a use method. A millimeter-level ultrasonic excitation probe and a laser detection probe device are integrated; a millimeter-level air coupling ultrasonic transducer is adopted to realize lossless and non-contact excitation of sample tissues; the three-dimensional structure and vibration information of the sample are detected and acquired by adopting a high-speed near-infrared swept-frequency laser; an ultrasonic probe and a laser probe device are integrated and packaged by adopting a 3D printing method, so that different application objects can be adapted; according to the non-contact optical coherence elastography endoscope method and device, an off-axis parabolic mirror is adopted to achieve confocal of ultrasonic pulses and excitation detection light beams, non-contact direct excitation and imaging can be achieved through an air medium, use of various coupling agents is avoided, and the non-contact optical coherence elastography endoscope device has the advantages of being simple in structure and easy to machine and integrate a system.

Provided herein are methods, devices, and systems that may improve optical resolution when imaging through a thickness of samples. A method for generating a depth profile of a tissue of a subject may comprise using an optical probe to transmit an excitation light beam from a light source towards a surface of the tissue; using one or more focusing units in the optical probe to simultaneously adjust a depth and a position of a focal point of the excitation light beam along a scanning path; detecting at least a subset of the signals generated upon contacting the tissue with the excitation light beam; and using one or more computer processors programmed to process the at least the subset of the signals to generate the depth profile of the tissue.

The present invention discloses a photolithography apparatus and method for forming a three-dimensional structure inside a photosensitive material configured to activate photochemical reactions according to a predetermined pattern in a layer inside the photosensitive material. A stage holds the volume of photosensitive material. A light source system produces an excitation beam of a first wavelength and a depletion beam of a second wavelength. A light modulation system forms one or more modulated images using the excitation beam and the depletion beam. An optical system focuses the one or more modulated images in a focal plane positioned inside the three-dimensional volume of photosensitive material. The focused one or more modulated images generate the predetermined pattern comprising one or more excitation regions and one or more depletion regions in the focal plane, selectively activating a photochemical reaction localized to a thin layer of the photosensitive material in the vicinity the focal plane.

An inspection system includes an excitation light source, a voltage-sensing film, an illumination light source, an image capture device. The excitation light source provides an excitation beam to light-emitting diodes to generate open-circuit voltages. The voltage-sensing film is at a top side of the light-emitting diodes and includes a voltage-sensing medium layer and a first electrode layer. The first electrode layer is in the voltage-sensing medium layer to provide a gain effect of the open-circuit voltages, so that the voltage-sensing medium layer senses the open-circuit voltages, and a display of the voltage-sensing medium layer is changed with a portion or all of the open-circuit voltages. The illumination light source provides an illumination beam to the voltage-sensing film to generate a sensing image according to a display change. The image capture device is on a transmission path of the sensing image and receives the sensing image to generate an inspection result.

The invention discloses a device for testing illumination uniformity of fluorescent glass, and relates to the technical field of fluorescent glass illumination. The device comprises a carrying platform module, a laser light source module, an optical collection module and a spectral analysis module, the carrying platform module is used for carrying and fixing a fluorescent glass sample to be detected and driving the fluorescent glass sample to rotate; the laser light source module is used for generating and outputting an excitation light beam to act on the fluorescent glass sample, and a light emitting path is adjustable; the optical collection module is used for collecting an optical signal emitted by the fluorescent glass sample; and the spectral analysis module is connected with the optical path of the optical output port of the optical collection module and is used for receiving and analyzing the optical signal. The device is simple in structure, controllable in cost, convenient to operate, capable of achieving high-spatial-resolution automatic scanning, high in measurement precision and good in repeatability.

A photoacoustic remote sensing system (PARS) for imaging a subsurface structure in a sample has an excitation beam configured to generate ultrasonic signals in the sample at an excitation location; an interrogation beam incident on the sample at the excitation location, a portion of the interrogation beam returning from the sample that is indicative of the generated ultrasonic signals; an optical system that focuses at least one of the excitation beam and the interrogation beam with a focal point that is below the surface of the sample; and a detector that detects the returning portion of the interrogation beam.

The present invention discloses a device for detecting the ferroelectric direction of a thin film under stress, which mainly consists of the following modules: an excitation light module: used for the polarization initialization, regulation, and stray light filtering of the incident fundamental frequency light. It includes an excitation light source - a femtosecond pulsed laser, which is used to generate an incident excitation light beam with a suitable frequency; it includes a polarizer, which is used for the polarization initialization of the incident light; it includes a lens A, which is used to focus the incident laser on the sample to be measured; it includes a rotatable half-wave plate controlled by electricity, which is used for the polarization regulation of the incident light. The present invention utilizes nonlinear optical detection to detect the ferroelectric direction of a thin film under stress, and provides a corresponding test system and method, which not only overcomes the problems of high sensitivity to the environment and difficult sample preparation process in the existing measurement technology, but also solves the problems that the sample is damaged during the measurement and cannot be further studied, etc.

A minority-carrier lifetime imaging system (100) and method for a semiconductor wafer. The system (100) comprises: a control module (110), which is used for generating a first electric pulse signal (Ep1) and a second electric pulse signal (Ep2); a light source module (120), which is used for generating a detection light beam (L1) and an excitation light beam (L2) on the basis of the first electric pulse signal (Ep1) and the second electric pulse signal (Ep2); a bearing module (130), which is used for fixing a wafer; a beam expansion module (140), which is used for enabling the detection light beam (L1) and the excitation light beam (L2) to be incident, by means of the beam expansion module (140), onto the wafer fixed on the bearing module (130), such that minority carriers on the wafer are converted from a ground state to an excited state under the excitation of the excitation light beam (L2), and the detection light beam (L1) detects the minority carriers in the excited state; and an imaging module (150), which is used for acquiring the minority carriers in the excited state that are detected by the detection light beam (L1), and generating a transient absorption image of the wafer, wherein the control module (110) is further used for generating a wafer minority-carrier lifetime image on the basis of the transient absorption image.

An illumination system including an excitation light source, a wavelength conversion device, a first light splitting module, a second light splitting module, a first light homogenizing element, and a second light homogenizing element is provided. Here, the excitation light source is configured to provide a laser beam. The wavelength conversion device is configured to convert the laser beam into an excited beam or a reflected laser beam at different timing. The first light splitting module is configured to reflect a first sub-laser beam of the laser beam from the wavelength conversion device to the first light homogenizing element. The second light splitting module is configured to reflect a second sub-laser beam from the first light splitting module to the second light homogenizing element. An illumination beam includes the first sub-laser beam, the second sub-laser beam, and the excited beam.

The invention relates to an optical system for monitoring a sample by fluorescence, comprising an excitation light source (2) generating an excitation light beam (F1) and a microfluidic card (1), said sample being placed in a microfluidic circuit integrated in said microfluidic card, said system comprising a device (3) for detecting the fluorescence signals (F2) generated by said sample after excitation, characterized in that: The system comprises optical polarization means positioned on the path of said light beam (F1), The optical polarization means being composed of at least a first optical polarizer (P1) and a second optical polarizer (P2),The optical polarization means being configured to select and illuminate a viewing area by acting on the orientation of the polarization direction of the first optical polarizer (P1) and on the polarization direction of the second optical polarizer (P2). Figure to be published with the abstract: Figure 2,

The invention relates to a coal isotope on-line detection system and method based on multi-wavelength coupling resonance enhancement, and the system comprises a laser generation unit which is configured to generate a preprocessing light beam and an excitation light beam, and a light beam guiding unit, the guiding assembly is configured to guide the pretreatment light beam and the excitation light beam to the surface of a coal mine sample in a fixed spatial relative position relation, and the scanning assembly is configured to drive the pretreatment light beam and the excitation light beam to synchronously scan the surface of the sample, so that the sample can be scanned at any scanning position. The preprocessing light beam always acts on the same sample point before the excitation light beam, and the preprocessing light beam is configured to preprocess the sample point so as to reduce the matrix effect of subsequent spectrum detection; the excitation light beam comprises a resonance laser component, the wavelength of the resonance laser component is matched with the characteristic wavelength of the element to be measured, and the excitation light beam is configured to generate plasma on the pretreated sample point and perform resonance excitation so as to obtain enhanced radiation light.

The invention relates to a method for localizing an emitter (F) in a sample (S), the method comprising illuminating the sample (S) with a stationary circular excitation beam (E), acquiring fluorescent photons; and estimating the position of the emitter (F) in the sample (S) from the acquired fluorescent photons. The invention also relates to a device (1) for localizing an emitter (F) in a sample (S), the device comprising an illumination means (10), an acquisition means (20) and a processing means (30), and to a computer program comprising instructions for causing the device (1) to perform the method for localizing an emitter (F).

The systems disclosed herein may a nanoscale chip. The chip includes a nanochannel with two nanoscale transverse dimensions and a SERS enhancement structure therein, alignment marks for enabling positioning of a laser excitation beam onto the enhancement structure, and a structural element for controlling the positioning of a polymer within the nanofluidic chip relative to the enhancement structure. The system may further comprise a reader for analyzing polymers on the chip. The disclosure also relates to methods of fabricating the chip and sequencing a polymer using the chip and reader.

The present application provides a crystal defect detection system, control method, medium, and program product. The crystal defect detection system is used to detect crystal defects in semiconductor devices. The crystal defect detection system includes: a stage, an excitation module, a detection module, an image acquisition module, and a data processing module. The excitation module is disposed on one side of the stage and is used to emit an excitation light beam to a target area of ​​the semiconductor device to excite the semiconductor device to generate carriers; the detection module is disposed on one side of the stage and is used to emit a detection light beam to the target area; the image acquisition module is disposed on one side of the stage and is used to receive a first light beam emitted from the semiconductor device and generate a first signal and a second signal based on the first light beam; the data processing module is used to generate crystal defect information about the target area based on the first signal and the second signal. The crystal defect detection system provided in the present application can perform non-destructive testing on semiconductor devices.

A multiplexing adaptive optics method for deep-tissue imaging is provided, comprising: providing a first optical beam and a group of second optical beams, each with lower intensity and distinct modulation frequencies; combining the beams with temporal overlap to form a composite excitation beam; focusing the composite beam into a sample such that the second optical beams are laterally separated in the focal plane; detecting a signal excited by the composite beam; demodulating the signal with reference frequencies to compute phase and amplitude data at each modulation frequency and obtain a second signal; performing spatial measurements of the first beam relative to the second beams to derive down-sampled electric-field point spread functions; and merging the functions to reconstruct a full-sampled point spread function for identifying and correcting optical aberrations within the sample.

The invention belongs to the technical field of optical microscopic imaging, and discloses a microscopic imaging system and a stimulated radiation loss microscope. The microscopic imaging system comprises an illumination mechanism used for providing a first light beam and a second light beam which are coaxially incident; the phase modulation optical device comprises multiple layers of diffractive optical elements, and the multiple layers of diffractive optical elements are arranged at intervals in the transmission direction of the first light beam and the second light beam and used for conducting phase modulation and convergence on the first light beam and the second light beam in a matched mode. And the first light beam and the second light beam can form a first light spot and a second light spot at the focal plane of the stimulated radiation loss microscope, and the first light spot and the second light spot are in one-to-one correspondence and coincide in center. According to the technical scheme of the invention, the stimulated radiation depletion microscope can be normally matched with a commercial laser which has a large bandwidth and wavelength drift and is used as an excitation beam and a depletion beam.

The invention discloses a portable Raman spectrometer based on Hadamard transform. The portable Raman spectrometer comprises a light source module, a sample bin, an optical system module, a detection module, a signal processing module and a control unit, the light source module is used for generating an excitation light beam to induce a target sample to generate Raman scattering light; an optical signal acquisition path is reconstructed through a space-spectrum cooperative coding mechanism of a Hadamard coding disc, multi-channel parallel capture in a full-spectrum range is realized in single exposure, and the luminous flux limitation of a traditional light splitting technology is fundamentally broken through; in combination with a dual optimization mechanism of dynamic weighting calculation, a closed-loop iteration model of noise suppression and weak signal enhancement is initiated, and signal-noise separation and fidelity reconstruction are realized on an algorithm level through real-time environmental noise analysis and Raman intensity gradient self-adaption.

The invention discloses a nano-cavity sensor for efficiently exciting fluorescence. The nano-cavity sensor comprises a quartz substrate layer, a micro-lens layer and a metal film layer which are sequentially arranged from bottom to top, the micro-lens layer is located above the quartz substrate layer and comprises a plurality of spherical-table-shaped micro-lenses protruding upwards; and the metal film layer is positioned on the quartz substrate layer and the micro lens layer, and is provided with through nano holes which are in one-to-one correspondence with the centers of the top planes of the table-shaped micro lenses. When exciting light enters, the spherical table type micro lens can focus a light beam emitted into the lens cavity from the bottom to the bottom of the nanopore to form a zero-mode waveguide effect, and fluorescent substances in the nanopore are excited through an evanescent field. The spherical table type micro lens modulates the direction of an excitation light beam, the light beam is converted into local enhanced excitation from parallel incidence, modulation of excitation photoelectric magnetic field distribution at the bottom of a nanopore and in a nanocavity in a solution environment is achieved, and distribution of an electromagnetic field is described by using a caustics line. According to the device, the excitation efficiency of a light path system on fluorescence is remarkably improved.

The present invention proposes a thin-walled structure ultrasonic guided wave nondestructive testing method based on flexible ultrasonic sensors, and the steps are: conducting guided wave focusing sound field simulation, obtaining the guided wave phased array focusing excitation scheme of the flexible ultrasonic sensor array, determining the design scheme of the flexible ultrasonic sensor array and the focusing excitation beam angle threshold; preparing the flexible ultrasonic sensor array according to the design scheme of the flexible ultrasonic sensor array; testing all channel electroacoustic parameters of the flexible ultrasonic sensor array, and returning if the relative error exceeds 10%; conducting a thin-walled structure guided wave sound field directivity test on the flexible ultrasonic sensor array, and adjusting the guided wave phased array focusing scheme if the beam angle is greater than the focusing excitation beam angle threshold; and using the flexible ultrasonic sensor array to perform defect detection on the thin-walled structure. The present invention has high structural integration, thin structure, small volume, and flexibility, and is suitable for defect detection and long-term online monitoring of thin-walled structures in narrow detection spaces, and has strong adaptability to the surface flatness of the structure.

The invention relates to a backscatter laser spectrometry device (1) comprising a laser source (30), an optical focusing system (50), an optical separator (60), and a spectrometer (80). According to the invention, the spectrometry device comprises a beam splitter (40) arranged on an optical path of the source light beam upstream of the optical separator, wherein the optical focusing system is arranged and configured to focus a first and a second secondary excitation light beam (402, 404) onto a first and a second measurement point (202, 204), respectively, wherein the optical focusing system is adapted to collect a first and a second backscattered light beam (412, 414), respectively, wherein the optical separator is adapted to direct the first and the second backscattered light beams toward a first and a second point (822, 824) at the entrance of the spectrometer, respectively, and wherein the spectrometer directs the first and the second backscattered light beams onto a first and a second zone (842, 844) on the multichannel detector, respectively.

The invention relates to a backscatter laser spectrometry device (1) comprising a laser source (30), an optical focusing system (50), an optical splitter (60), a spectrometer (80).According to the invention, the spectrometry device comprises a beam splitter (40) disposed on an optical path of the source light beam upstream of the optical splitter, the focusing optical system being arranged and configured to focus the first, respectively second, secondary excitation light beam (402, 404) onto a first, respectively second, measurement point (202, 204), said focusing optical system being adapted to collect a first, respectively second, backscattered light beam (412, 414), the optical splitter being adapted to direct the first, respectively second, backscattered light beam to a first, respectively second, point (822, 824) of the spectrometer inlet, the spectrometer directing the first, respectively second, backscattered light beam onto a first, respectively second, area (842, 844) of the multichannel detector. Figure for the abstract: Fig. 1.