The present application provides a flow path cleaning method for an automatic sampler, which can balance the decrease of analysis
throughput and the increase of cleaning solution consumption. In a flow path cleaning process (S12), when a cleaning solution is supplied by a cleaning solution supply mechanism to a flow path switched by a flow
path switching mechanism among a first flow path including a
nozzle for sucking a sample and a sample ring for holding the sample sucked from the
nozzle, and a second flow path including a cleaning tank for cleaning at least an outer wall of the
nozzle, a control device changes a flow rate of the cleaning solution supplied between measurement of a first measurement item of the sample and measurement of a second measurement item of the sample, based on first cleaning information indicating a cleaning mode corresponding to the first measurement item of the sample, and second cleaning information indicating a cleaning mode corresponding to the second measurement item of the sample measured after the first measurement item.