The invention relates to a health risk assessment and disease early warning information system, and belongs to the technical field of health management. The system comprises an employee health management system and a personal health system; the employee health management system comprises 11 modules such as an employee basic information management module, an employee health data acquisition module,and an employee health questionnaire management module; the personal health system consists of an ordinary user registration sub-module, a personal information management sub-module, a personal health history management sub-module, a daily health monitoring sub-module, a medical sick rest management sub-module, a health questionnaire sub-module, an annual health examination sub-module, a health condition assessment sub-module, a disease risk assessment sub-module, a health promotion management sub-module, and a health consultation forum sub-module. The health risk assessment and disease earlywarning information system forms an integrated network management mode of health management, health risk assessment and health risk intervention control.