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227 results about "Clinical decision" patented technology

Clinical decision making is a balance of known best practice (the evidence, the research), awareness of the current situation and environment, and knowledge of the patient. It is about 'joining the dots' to make an informed decision.

System and method for improving clinical decisions by aggregating, validating and analysing genetic and phenotypic data

The information management system disclosed enables caregivers to make better decisions, faster, using aggregated genetic and phenotypic data. The system enables the integration, validation and analysis of genetic, phenotypic and clinical data from multiple subjects who may be at distributed facilities. A standardized data model stores a range of patient data in standardized data classes that encompass patient profile information, patient symptomatic information, patient treatment information, and patient diagnostic information including genetic information. Data from other systems is converted into the format of the standardized data classes using a data parser, or cartridge, specifically tailored to the source system. Relationships exist between standardized data classes that are based on expert rules and statistical models. The relationships are used both to validate new data, and to predict phenotypic outcomes based on available data. The prediction may relate to a clinical outcome in response to a proposed intervention by a caregiver. The statistical models may be inhaled into the system from electronic publications that define statistical models and methods for training those models, according to a standardized template. Methods are described for selecting, creating and training the statistical models to operate on genetic, phenotypic and clinical data, in particular for underdetermined data sets that are typical of genetic information. The disclosure also describes how security of the data is maintained by means of a robust security architecture, and robust user authentication such as biometric authentication, combined with application-level and data-level access privileges.
Owner:NATERA

Electronic medical record phenotype extraction and phenotype name normalization method and system

The invention discloses an electronic medical record phenotype extraction and phenotype name normalization method. The method comprises the following steps: phenotypic extraction: taking natural statements of a medical record text as original data, and adopting Bi-; Named entity recognition is carried out on the LSTM model and the CRF model, and a phenotypic entity class is extracted; And phenotype standardization is carried out, an LSTM encoder is adopted to encode each phenotype, cosine similarity between non-standard phenotype codes and standard phenotype codes in the medical records is calculated, and the non-standard phenotype codes are mapped to the phenotype with the highest cosine similarity. The invention further discloses an electronic medical record phenotype extraction and phenotype name normalization system. According to the method, the named entity identification accuracy, the recall accuracy and the phenotypic mapping accuracy in the electronic medical record are improved; The labor consumption in the medical record structuring process is avoided, and the medical record structuring efficiency is improved; The method can more efficiently and accurately serve medical data mining, clinical decision support, clinical risk assessment and the like.
Owner:TSINGHUA UNIV

Methods and System for Real Time, Cognitive Integration with Clinical Decision Support Systems featuring Interoperable Data Exchange on Cloud-Based and Blockchain Networks

An informatics platform comprising method, system, and computer program is provided for interacting with clinical decision support systems such as the IBM Watson for Oncology, for the purpose of utilizing cognitive processing, machine learning and natural language processing to facilitate the manual to semi-automatic to automatic acquisition of a patient's electronic medical record data points, into a CDS system for populating the attributes questionnaire, for generating a patient diagnostic report of treatment recommendations. The platform supports deployment on several informatics architectures including client-server, cloud-based and blockchain.
In a typical embodiment, the system is deployed as a Software-as-a-Service (SAAS) application; it implements a cloud-based, real-time architecture comprising: (a) an adaptive user interface providing responsive dashboards for real-time data presentation and user interaction, (b) a hub controller for real-time data flow transformation, (c) a data validation engine which incorporates cognitive natural language processing (NLP) to extract structured and unstructured patient record data from the EHR and employs methods that provide an optimally automated input to the CDS, (d) cloud storage of aggregated CDS data and other clinical datasets, and (e) plug-in support for additional cognitive capabilities such as predictive analytics and data mining.
Owner:PATIENT ONCOLOGY PORTAL INC
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