143 results about "Genetic data" patented technology

This invention provides a process and system for a comprehensive surgical assist system, called a Therapy Imaging and Model Management System (TIMMS), which combines and integrates all of the necessary information and communication technology; workflow analysis, data processing and data synthesis; interactive interfaces between surgeon and mechatronic devices; and, cognitive agents; to provide comprehensive assistance and guidance throughout complex medical and surgical therapies, such as image guided surgery. The components of this invention, which are modular, scalable and may be distributed in location, act synergistically to provide functionality and utility that exceeds the sum of its individual parts.

A method of performing surgery on a patient comprising the step of comparing a chosen patient's data to statistical data in a repository of patient data to develop a patient specific model, wherein the data comprises information from two or more sub databases selected from the group consisting of workflow data, electronic medical records, diagnostic data, biological data, measurement data, anatomical data, physiological data, genetic data, molecular data, imaging data, chemical data, clinical laboratory data, simulated data, coordinate data and surgical result and wherein the patient specific model aids in the preoperative, operative or post operative phase of surgery performed in real time on the patient.

Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Genetic material from the target individual is acquired, amplified and the genetic data is measured using known methods. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment of the invention, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment of the invention, the chromosome copy number can be determined from the measured genetic data of a single or small number of cells, with or without genetic information from one or both parents. In another embodiment of the invention, these determinations are made for the purpose of embryo selection in the context of in-vitro fertilization. In another embodiment of the invention, the genetic data can be reconstructed for the purposes of making phenotypic predictions.

Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.

A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, are disclosed. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects. In accordance with one embodiment of the invention, incomplete genetic data is acquired from embryonic cells, fetal cells, or cell-free fetal DNA isolated from the mother's blood, and the incomplete genetic data is reconstructed using the more complete genetic data from a larger sample diploid cells from one or both parents, with or without genetic data from haploid cells from one or both parents, and/or genetic data taken from other related individuals.

Disclosed herein is a system and method for increasing the fidelity of measured genetic data, for making allele calls, and for determining the state of aneuploidy, in one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available. Poorly or incorrectly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related individuals. In accordance with one embodiment, incomplete genetic data from an embryonic cell are reconstructed at a plurality of loci using the more complete genetic data from a larger sample of diploid cells from one or both parents, with or without haploid genetic data from one or both parents. In another embodiment, the chromosome copy number can be determined from the measured genetic data, with or without genetic information from one or both parents.

A method for conducting genetic research on medical data. The method includes the step of accessing a database storing a plurality of medical records associated with a plurality of individuals, each medical record including at least one unique identifier associated with a certain individual and medical data associated with the certain individual. The method also includes the steps of extracting from the database the medical data associated with at least a subset of the plurality of individuals and, for each individual of the subset, obtaining electronically stored genetic data associated with the respective unique identifier. Also, the method includes processing the extracted medical data and obtained genetic data for attempting to identify an association between particular genetic data and a particular medical condition.

A life expectancy management system which comprises: a storage means which is capable of storing data, such as genetic data, birth data, lifestyle data, pediatric health data, and adulthood health data; a means for altering the data based upon the occurrence of at least one event selected from the group consisting of: chronic and routine health events, emergency health events, pregnancy data and medical advancements; and a prediction modeling logic which provides a predetermined life expectancy that can be reduced by deviations from expectations which are calculated from the data and altered or adjusted data. Optionally, a means for providing recommended goals based upon the life expectancy predicted and the predetermined life expectancy.

The invention provides a vehicle identification data processing method. The method includes the steps of obtaining vehicle bus data through a vehicle bus, wherein the vehicle bus data include an engine identification code and further include at least one of vehicle bus configuration data, vehicle system configuration data, trip computer parameters, the vehicle bus type, the vehicle communication protocol category and vehicle delivery capacity; generating vehicle genetic data according to the combination of the vehicle bus data, uploading the vehicle genetic data to a data processing server, wherein the vehicle genetic data are used for vehicle identification. According to the vehicle identification data processing method, the vehicle genetic data uploaded to the data processing server have high uniqueness, vehicle identification can be achieved according to the vehicle genetic data so that different vehicles can be distinguished, and the method can be widely applied to various fields such as the traffic management field, the investigation field and the vehicle positioning field. The invention further provides a vehicle identification data processing device and system.

Method and system for preparing a personal genetic profile includes collecting genetic data from an individual, assigning the data to a coordinate system, storing the data, and providing access for retrieval by the individual from whom the genetic data were collected, after receipt of an Identifier that adequately authenticates the identity of the data requestor. Locations of genetic markers are provided as three-dimensional coordinates, described with matrix relationships that are consistent with the primary and secondary chemical structure of molecular constituents of a DNA chain for the individual.

Creation of a social genetics network that provides personal and business services includes: receiving non-genetic data and genetic data about a user and storing the non-genetic data and genetic data in a database; analyzing the genetic data and the non-genetic data to i) assign traits to the user based at least in part on phenotypic and/or genotypic relationships found in the genetic data and the non-genetic data, and ii) determine trait connections between the user and other users in the network based on a similarity of the traits that are common to the user and the other users; and generating and displaying on an electronic device a social genetics profile that includes at least a portion of the non-genetic data, at least a portion of the traits assigned to the user, and at least a portion of the trait connections of the user to the other users.

Disclosed herein are methods, systems, and media for managing health information that enable individuals to create a profile, associate fitness data, genetic data, and medical data and designate one or more recipient successors for all or part of their profile to create a health trust. Also disclosed herein are methods, systems, and media for providing a marketplace for health information by maintaining a database of profiles, each profile including personal information, fitness data, genetic data, and medical data for the individual, applying an algorithm to generate a monetary market value for each profile, enabling health data consumers to conduct a search of the database, and enabling the health data consumers to select identified profiles and subscribe to the selected profiles.

A system and method are presented for identifying a suitable tissue donor for an intended tissue recipient. A database of individuals is provided that comprises, for each individual, genetic data parameters comprising hereditary parameters that play a role in tissue-typing for matching between donor and recipient and comprises genealogical data for a plurality of individuals including at least some of said individuals for whom the genetic data is provided in the database. A recipient tissue type (RTT) is determined for the intended tissue recipient. The database is searched for one or more individuals that have a degree of similarity to the RTT that satisfy predetermined criteria to thereby identify one or more pivot individuals. A search is conducted for a target group of target individuals that includes the pivot individuals and individuals that are genetically related to the pivot individuals, and output data indicative of search results is generated.

The present invention discloses the use of Allele-Specific-oligonucleotide (ASO) as a detection assay for human HLA classification. Using Reversed-Dot-Blotting format and flow through hybridization process, more efficient, faster and less expensive HLA classification can be achieved. A simplified procedure for HLA genotyping is also described. This invention further provides a Single Nucleotide Polymorphism (SNP)-based DNA fingerprining method for rapid and accurate genotyping, identification as well as DNA analyses of genetic data from human beings and different organisms. In addition this invention also discloses a new device for rapid and sensitive analyses of nucleic acids, proteins and other analysts for diagnosis.

A system and method for determining the genetic data for one or a small set of cells, or from fragmentary DNA, where a limited quantity of genetic data is available, and also for predicting likely phenotypic outcomes using mathematical models and given genetic, phenotypic and/or clinical data of an individual, and also relevant aggregated medical data consisting of genotypic, phenotypic, and/or clinical data from germane patient subpopulations. Genetic data for the target individual is acquired and amplified using known methods, and poorly measured base pairs, missing alleles and missing regions are reconstructed using expected similarities between the target genome and the genome of genetically related subjects.

Method and system for preparing a personal genetic profile includes collecting genetic data from an individual, assigning the data to a coordinate system, storing the data, and providing access for retrieval by the individual from whom the genetic data were collected, after receipt of an Identifier that adequately authenticates the identity of the data requester. Locations of genetic markers are provided as three-dimensional coordinates, described with matrix relationships that are consistent with the primary and secondary chemical structure of molecular constituents of a DNA chain for the individual.