The invention is applied to the mobile terminal technology field, and provides a method for preventing loss of a mobile phone and the mobile phone. According to the method, through a G-sensor, a mobile phone state signal is detected in real time and an acquired signal is sent to a central processor; through the G-sensor, whether continuous weight loss time of the mobile phone exceeds first predetermined time or not is determined, if the continuous weight loss time exceeds the first predetermined time, falling of the mobile phone is determined, and simultaneously an alarm module is triggered to open a mobile phone loudspeaker with maximum volume and the loudspeaker plays alarm music to prompt a user; whether the fallen mobile phone is picked up within second predetermined time or not is determined, if so, alarm is stopped, and otherwise, a short message is automatically sent to a user preset number to prompt the user that the mobile phone is lost. By utilizing the method and the mobile phone, probability of losing the mobile phone of the user can be substantially reduced, design structure is simple, and user usage experience and user satisfaction are raised.