The invention relates to a plaster for treating rheumatism which is prepared from 40 traditional Chinese medicinal materials including syngnathus, pubescent angelica, angelica, agkistrodonbungarus minimus, peach kernel, safflower, phellodendron, radix sileris, catnip, asarum, pinellia ternate, yazao, erhua, forsythia, pangolin, nux vomica, rhizoma gastrodiae, panax notoginseng, papaya, hyssop, cortex eucommiae, cassia twig, olibanum, myrrh, angelica, coptis, notopterygium, fritillaria, sophora, whole worm, centipede, dragon's blood, radix auckladiae, realgar, musk, clove, borneol, astragalus, sesame oil and guangdan. The plaster has special curative effect for treating intractable rheumatism, and has advantages of quick result, short treatment period, high cure rate and low cost.