18results about How to "Formulation Science" patented technology

The invention provides a pharmaceutical composition for treating rhinitis. The pharmaceutical composition is prepared from the following raw materials in parts by weight: 105 to 245 parts of herba houttuyniae, 60 to 140 parts of flos chrysanthemi indici, 60 to 140 parts of flos lonicerae, 15 to 35 parts of herba centipedae, 60 to 140 parts of herba senecionis scandentis, 1.2 to 2.8 parts of fructus xanthii oil, 1.2 to 2.8 parts of flos magnoliae oil, 0.9 to 2.1 parts of peppermint oil, 0.9 to 2.1 parts of borneol, 0.6 to 1.4 parts of radix angelicae dahuricae oil, 0.15 to 0.35 part of rhizoma chuanxiong oil and 0.15 to 0.35 part of notopterygium root oil. The invention also provides a preparation method and application of the composition. The gel is prepared by directly adding other auxiliary materials on the basis of the traditional Chinese medicine extract, the prepared gel has good affinity with the nasal cavity, allergens can be effectively isolated, nasal cavity symptoms can be improved, the process is simple, the formula is scientific, and the curative effect is remarkable.

The invention discloses high-dosage rubber powder modified asphalt and a preparation method thereof, and the rubber powder modified asphalt is prepared by adding 22-30 parts by weight of modified rubber powder into 100 parts by weight of road petroleum asphalt, the modified rubber powder is prepared from the following components in parts by weight: 85 to 95 parts of common rubber powder, 3 to 6 parts of phenolic resin, 0.6 to 1.2 parts of microcrystalline wax, 2 to 5 parts of naphthenic oil, 0.2 to 0.6 part of antioxidant and 0.2 to 0.6 part of EVA (Ethylene Vinyl Acetate). The preparation method comprises the following steps: (1) preparing the modified rubber powder; and (2) preparing the modified asphalt cement. According to the invention, co-melting and blending of the rubber powder and the asphalt are improved, the mixing amount of the rubber powder in the rubber asphalt can be obviously increased, the pavement and durability are greatly improved, the production cost and environmental pollution of the asphalt mixture are effectively reduced, and the asphalt mixture has economic and social double benefits, is simple in preparation process and has relatively high practical application value.

The invention discloses salt baked flavor chicken energy chewable tablets and a preparation method thereof, and belongs to the technical field of food processing. The chewable tablet consists of the following components in percentage by weight: 20-40 parts of salt roasted chicken powder, 25-50 parts of an energy supplement, 0.1-0.5 part of composite vitamins, 10-30 parts of an excipient, 0.5-2 parts of a flavoring agent, 0.1-0.5 part of an antioxidant, 1-3 parts of magnesium stearate and the balance of deionized water. The salt-baked chicken powder is prepared by taking chicken breast as a raw material, rolling, kneading and pickling with a salt-baked flavor pickling solution, steaming, drying and pulverizing. According to the invention, the salt baked flavor and the nutrition of chicken are combined, the salty and fragrant flavor and balanced nutrition are combined, rapid and lasting energy supplementation can be realized, the chewable tablet is portable to eat, is subjected to dry granulation, low-temperature sterilization and aluminum foil packaging, has long shelf life, adopts a natural flavoring agent, is high in safety, and is suitable for various energy supplementation scenes such as sports, offices, outdoors and the like.

This invention discloses a traditional Chinese medicine composition for replenishing qi and nourishing blood, and its preparation method, belonging to the technical field of food-medicine homology traditional Chinese medicine health care preparations. The composition of this invention uses oyster peptide powder, compound amino acid powder, polygonatum powder, maca powder, eucommia male flower powder, ginseng powder, cordyceps powder, and earthworm protein peptide powder as core active ingredients, supplemented with deer antler powder, deer tendon powder, and deer blood peptide powder to enhance the effects of strengthening the body and nourishing blood. It is combined with xylitol, corn starch, maltodextrin, magnesium stearate, and caramel color as molding excipients. The dosage of each component is precisely controlled. Through a proprietary preparation process involving raw material pretreatment, segmented gradient mixing, and refined post-processing, a 1g / tablet formulation is prepared. The formulation of this invention is rigorously formulated, with clear distinctions between principal, assistant, and adjuvant ingredients, and each component synergistically enhances its effect. It can fundamentally improve problems such as qi and blood deficiency, insufficient vital energy, fatigue, and physical weakness. It has comprehensive efficacy, rapid onset of action, and wide applicability, possessing extremely high industrial promotion and health care application value.

The invention provides a rare earth liquid softener and a preparation method thereof, and belongs to the technical field of rare earth bactericidal bacteriostatic agents. According to the rare earth liquid softener provided by the invention, the softener is endowed with excellent antibacterial and bacteriostatic ability due to the addition of the rare earth complex, the survival rate of harmful bacteria is effectively reduced, and additional health protection is provided. Meanwhile, the formula of the softener strictly follows the environmental protection principle, the selected raw materials are environmentally friendly and non-toxic, it is ensured that the comfort of clothes is improved, meanwhile, the softener is harmless to the human body and the environment, and the requirements of modern consumers for green products are met. The softener provided by the invention is scientific in formula design, ensures the safety and reliability of the product, provides a brand-new solution for clothing care due to the characteristics of high efficiency, environmental protection and safety, is suitable for wide fabric types, and meets the requirements of different users.

The invention relates to the technical field of traditional Chinese medicine, and particularly discloses an external traditional Chinese medicine preparation for conditioning and treating heart diseases and a preparation method thereof.The traditional Chinese medicine preparation is prepared from ginseng, cornu cervi pantotrichum, radix polygoni multiflori preparata, the root of red-rooted salvia, the root of kudzu vine, rhodiola rosea, angelica sinensis oil, ligusticum wallichii oil, clove oil, rose oil, safflower oil and peppermint oil. The traditional Chinese medicine compound extracting solution composition is obtained by mixing a plurality of dry raw materials, respectively performing liquid extraction on the plurality of dry raw materials to obtain traditional Chinese medicine essential oil extracting solutions, and then performing compound combination on the plurality of traditional Chinese medicine essential oil extracting solutions, and the traditional Chinese medicine compound extracting solution composition is used for preparing traditional Chinese medicine oil for conditioning and treating heart diseases. The traditional Chinese medicine is scientific in formula and simple to prepare, has the effects of promoting blood circulation to remove blood stasis, replenishing blood and qi, strengthening heart and benefiting kidney, dredging channels and collaterals and clearing heat and relieving depression, and can effectively condition and treat heart diseases.

This invention provides a method for preparing a metformin compound hypoglycemic oral solution, relating to the pharmaceutical field, comprising: step S1, pretreatment of traditional Chinese medicine components; step S2, enzymatic hydrolysis of the first group of traditional Chinese medicine components; step S3, supercritical extraction; step S4, preparation of mixed traditional Chinese medicines; step S5, preparation of inclusion complex; step S6, compound formulation; and step S7, post-processing. This method synergistically combines extracts from seven traditional Chinese medicines—bitter melon, phellodendron bark, astragalus root, kudzu root, rehmannia root, ginseng, and privet fruit—with metformin hydrochloride to form a metformin compound hypoglycemic oral solution, balancing the synergy, safety, and stability of traditional Chinese and Western medicines, thereby improving hypoglycemic effects while reducing the incidence of gastrointestinal adverse reactions to metformin.

The invention relates to the technical field of health-care food, in particular to a Lushenkangyuan brand tea polyphenol, grape seed and American ginseng capsule helpful for resisting oxidation. Comprising the following compositions in percentage by weight: 20%-30% of tea polyphenol, 15%-25% of a grape seed extract, 10%-20% of an American ginseng extract, 10%-15% of dextrin and 0.01%-0.05% of magnesium stearate, and the total content of the tea polyphenol, the grape seed extract and the American ginseng extract is 45%-75%. According to the present invention, the effects of scientific formula, high active component content, clear dual anti-oxidation mechanism, and significant synergistic effect among the components are achieved.

The invention discloses a method for extracting and purifying lysimachia capillipes saponin B. The lysimachia capillipes saponin B is prepared from the following components in parts by mass: 100 parts of schisandra chinensis, 0.05 to 0.8 part of mannitol, 0.01 to 0.3 part of sodium hydroxide, 0.01 to 0.3 part of maleic acid, 0.03 to 0.5 part of propylene glycol and 400 to 4000 parts of water for injection. Meanwhile, the invention further discloses a preparation method of the method for extracting and purifying the lysimachia capillipes saponin B in the schisandra propinqua. According to the present invention, the formula design is scientific, the whole formula preparation is rigorous through the stabilizer propylene glycol, the cosolvent mannitol and the pH regulator sodium hydroxide and the maleic acid, the by-products are as few as possible, and the multi-stage temperature control sterilization mode is adopted to effectively inactivate the bacteria possibly existing in the mixed liquid so as to achieve the injection quality standard.

The application discloses a soil conditioner and a preparation method and application thereof, and relates to the technical field of solid waste resource utilization and soil ecological restoration. The soil conditioner comprises coal gangue, old acid mother liquor, sheep manure and wood mold in percentage by weight, wherein the coal gangue accounts for 69-87.5%, the old acid mother liquor accounts for 0.5-2%, the sheep manure accounts for 10-25%, and the wood mold accounts for 2-4%. The application constructs a four-element synergistic system with the coal gangue as a mineral carrier, the old acid mother liquor as an organic acid activator, the sheep manure as an organic long-acting fertilizer source and the wood mold as a biological control core, and the four materials are scientifically compounded, researched and optimized, so that the physical, chemical and biological effects of the four materials are synergistically exerted to form an efficient sand land conditioner. The application has outstanding improvement effect: the conditioner can significantly promote the growth of soybeans in sand land. Compared with CK, the plant height, stem diameter and total biomass of the soybeans are increased by 33%, 126% and 112% respectively, and the total root length and root tip number of the soybean roots are doubled. The comprehensive effect of the application is significantly better than that of the traditional single sheep manure or conventional chemical fertilizer treatment.

The application relates to the field of traditional Chinese medicines, and discloses a traditional Chinese medicine composition, a traditional Chinese medicine preparation, a preparation method and application thereof. The traditional Chinese medicine composition contains angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, frankincense, myrrh, radix rubi sylvestris, natural copper, elderberry, radix curdlane, crab shell and zhangdan. The preparation method of the traditional Chinese medicine preparation comprises the following steps: mixing angelica sinensis, safflower, red peony root, salvia miltiorrhiza, radix aconiti kusnezoffii, radix aconiti carmichaeli, cassia twig, drynaria, radix rubi sylvestris, radix rubi sylvestris, natural copper, elderberry, radix curdlane and crab shell with vegetable oil to perform frying and boiling, performing solid-liquid separation to obtain medicine oil; mixing the medicine oil after being refined with zhangdan, frankincense and myrrh to obtain an ointment; soaking the ointment in water, taking out, heating and melting, mixing with blood ointment powder, and spreading. The traditional Chinese medicine composition and the traditional Chinese medicine preparation have the effects of setting bone, continuing tendon and relieving swelling and pain.

This invention relates to the field of traditional Chinese medicine preparation technology, specifically to a Qi-invigorating and blood-activating granule for heart pain and its preparation method, comprising the following raw materials in parts by weight: 25-35 parts of raw Astragalus membranaceus, 10-20 parts of Angelica sinensis, 5-15 parts of ginseng, 4-8 parts of Panax notoginseng, 10-20 parts of Ligusticum chuanxiong, 8-12 parts of earthworm, and 2-4 parts of leech. This invention precisely targets the core pathogenesis of Qi deficiency and blood stasis syndrome, which is "Qi deficiency as the root and blood stasis as the manifestation," selecting raw Astragalus membranaceus and ginseng as the core Qi-invigorating components, and Panax notoginseng, leech, Ligusticum chuanxiong, Angelica sinensis, and earthworm as the core blood-activating components. The formulation follows the traditional Chinese medicine principle of "invigorating Qi to promote blood circulation without harming the body's vital energy." The dosage of each raw material has been optimized through systematic experiments to form a specific range of parts by weight, solving the technical problems of poor targeting and insufficient synergy in existing formulations.

The invention relates to the technical field of cylinder sleeve manufacturing, in particular to a medium for micro-surface treatment of a cylinder sleeve and a preparation method of the medium. The medium for micro-surface treatment of the cylinder sleeve, provided by the invention, is prepared from sodium bentonite, green silicon carbide, C12-18 fatty alcohol polyoxyethylene (25) ether, lignosulfonate, polyaniline and water according to a certain proportion, and the medium can be used for changing a common electrochromism surface into a loose-hole chromism surface in a mechanical extrusion manner; the method ensures that the inner surface of the engine cylinder sleeve has good oil storage performance, ensures that the cylinder sleeve with the chromium-plated inner hole has good lubricity during operation of an engine, is good in process operability, and improves the productivity and the qualification rate of the cylinder sleeve.

The present invention relates to a Chinese medicine composition for invigorating qi and promoting blood circulation and its application in preparing a drug for treating cardiovascular aging. The composition comprises 13 kinds of Chinese medicinal materials: epimedium and / or epimedium extract, schisandra and / or schisandra extract, gynostemma pentaphyllum and / or gynostemma pentaphyllum extract, psoralea corylifolia and / or psoralea corylifolia extract, acanthopanax and / or acanthopanax extract, ginseng and / or ginseng extract, licorice and / or licorice extract, osmanthus fragrans and / or osmanthus fragrans extract, immature bitter orange and / or immature bitter orange extract, tangerine peel and / or tangerine peel extract, angelica and / or angelica extract, white peony root and / or white peony root extract, red peony root and / or red peony root extract. The Chinese medicine composition for invigorating qi and promoting blood circulation of the present invention is obtained by extracting and matching different active ingredients of 13 kinds of Chinese medicinal materials to obtain the best formula, which can significantly improve the antioxidant activity of the body, promote macrophage proliferation, slow down the aging speed of the body, and maintain the vitality of the body.

The invention discloses a preparation method of cat food with prebiotics stomach conditioning efficacy, and relates to the related technical field of animal feeds, the cat food comprises the following main components: meat, carbohydrate, fruits and vegetables, prebiotics and an additive; the preparation method specifically comprises the following steps: sorting and cooking; performing crushing treatment; mixing the ingredients; granulating and forming; performing vacuum spraying; baking and packaging. According to the cat food processed by the processing method disclosed by the invention, the cat food is rapidly processed by adopting a pre-rapid cooking mode in the processing process, the puffing time is shortened, nutrient loss is effectively reduced, meanwhile, the original flavor is not influenced, the raw materials are fully treated, including cooking meat, squeezing and separating liquid fat, and the like, so that the processing and blending of the raw materials are facilitated; by adopting an external layered wrapping mode, the palatability of the cat food is prevented from being influenced, the ingestion rate is ensured, and meanwhile, the compound probiotic factors are added, so that the establishment of normal flora balance in intestinal tracts is facilitated, and the intestinal protection and immune regulation capabilities of the cat food are improved.

The invention relates to the technical field of traditional Chinese medicine, and discloses a traditional Chinese medicine composition for relieving lumbago, a traditional Chinese medicine preparation and a preparation method and application thereof. The traditional Chinese medicine composition contains rheum officinale, pinellia ternate, cape jasmine, coptis chinensis, goat bones, cucumber seeds, prepared kusnezoff monkshood roots, curcuma zedoary, ground beetles, artemisia rupestris, frankincense, myrrh and liquorice. The preparation method of the traditional Chinese medicine preparation for relieving lumbago comprises the following steps: mixing a mixture A of rheum officinale, pinellia ternate, cape jasmine, coptis chinensis, goat bones and cucumber seeds with a solvent containing monohydric alcohol, carrying out alcohol extraction for at least one time, and collecting an alcohol extract; and mixing the mixture B of prepared kusnezoff monkshood root, curcuma zedoary, ground beetle, artemisia rupestris, frankincense, myrrh and liquorice with water, decocting for at least one time, and performing solid-liquid separation to obtain the water extract. The invention also provides application of the traditional Chinese medicine composition prepared by the method or the traditional Chinese medicine preparation prepared by the method in medicines for relieving back pain. The traditional Chinese medicine composition has the effects of relieving pain, diminishing swelling, dredging collaterals and strengthening tendons and bones.

The invention discloses a formula of an additive for feeding egg-laying ostriches. The formula consists of composite vitamins and a plurality of mineral substances. The special additive formula for the egg-laying ostriches mainly aims to effectively prevent and treat the unhairing phenomenon of the egg-laying ostriches, reduce the stress response of the egg-laying ostriches, better supplement vitamins and minerals to the ostriches, and promote the growth and development of the ostriches, and is comprehensive in nutrition. The feed additive is a vitamin type additive, so that the feed additive is simple in feeding mode, is suitable for being added into various feeds, and can be independently fed. The method is low in cost and suitable for batch production.

The invention relates to the technical field of gel for women, and provides recombinant collagen antibacterial gel for women and a preparation method of the recombinant collagen antibacterial gel for women, and the recombinant collagen antibacterial gel for women comprises the following components in percentage by weight: 0.1-1.9% of carbomer; 0.8 to 1.1 parts of recombinant collagen; 1 to 1.5 parts of hydroxyethyl cellulose; 0.1 to 0.3 part of sodium hydroxide; 0.2 to 1.5 parts of isomaltooligosacharide; 3-8 parts of propylene glycol; 0.1 to 1 part of sodium ethyl paraben; 0.1 to 1 part of sodium ethyl paraben; 80 to 95 parts of purified water; the traditional Chinese medicine composition is used for treating itching, erosion, pain and private part peculiar smell symptoms caused by cervicitis and vaginitis and reducing leucorrhea increase. The preparation method comprises the following steps: S1, raw material acceptance inspection; s2, material picking; s3, weighing and batching; s4, preparing; s5, filling; s6, inner packaging; s7, external packaging; and S8, warehousing. According to the technical scheme, the problems that the application effect is poor, a film-shaped structure of the antibacterial gel has large gaps, part of gaps still exist, and part of small pathogenic microorganisms can enter a human body through the gaps are solved.