The invention discloses a Procambrus clarkii culture granulated feed and a production method thereof. The Procambrus clarkii culture granulated feed is prepared from the following raw materials: fish meal, meat and bone meal, bean pulp, rapeseed meal, peanut meal, flour, rice bran, squid cream, shrimp bran, ecdysone, adhesive, table salt, monocalcium phosphate, zeolite powder, premix, mixed grease (wherein, the ratio of fish oil to soya-bean oil to lard oil is equal to 2-3:1:1), Rhubarb anthraquinone and the like. The preparation method comprises: stirring and mixing in a stirrer; meanwhile, adding steam; pelletizing, dewatering and cooling; and finally preparing the Procambrus clarkii culture compound granulated feed. The Procambrus clarkii culture compound granulated feed prepared by the production method has the advantages of good taste attractant and palatability, high stability in water, normal exuviation, low autotomy rate, high growth speed, low bait coefficients and the like. The Procambrus clarkii culture compound granulated feed can be utilized to obtain the optimal culture effect according to the specific culture situation when being used for cultivating the Procambrus clarkii.