75results about How to "Improve stress response" patented technology

The invention relates to the organic fertilizer field, in particular to tobacco powder biological organic fertilizer formula and production method thereof. The invention is characterized in that the formula includes the following components by parts by weight: 5-6 parts of tobacco powder, 0.5-1.5 parts of brown coal, 1.5-2.5 parts of live stock excrement and 1-2 parts of straw powder. The tobacco powder biological organic fertilizer is complete in nutrient elements and can regulate soil, activate micro organism liveness in soil, overcome soil hardening and improve soil air permeability; insect pest in soil can be effectively killed; stress resistance of crop is improved, stress reaction of crop is improved, and deformity is reduced; the organic fertilizer is safe and notoxic to human, live stock and environment; the organic fertilizer uses tobacco powder of cigarette factory and redrying factory and straw powder as main raw materials, solves the problems that tobacco powder of the cigarette factory and redrying factory is difficult to treat and secondary pollution is caused by direct burning of the tobacco powder and straw and is environmentally friendly.

The invention relates to a water purifying agent for pond culture. The water purifying agent is powdery mixture which is prepared by uniformly mixing the following components in part by weight: 100 to 200 parts of bacillus subtilis, 100 to 200 parts of nitrobacteria, 150 to 200 parts of photosynthetic bacteria and 400 to 650 parts of zeolite powder, wherein the water purifying agent preferably comprises 100 parts of bacillus subtilis, 100 parts of nitrobacteria, 150 parts of photosynthetic bacteria and 650 parts of zeolite powder; the bacillus subtilis is light yellow powder and the total count of viable bacteria is more than or equal to 200 hundred million per one gram; the nitrobacteria is light grey powder and the total count of the viable bacteria is more than or equal to 80 hundred million per one gram; the photosynthetic bacteria is grey white powder and the total count of the viable bacteria is more than or equal to 30 to 50 hundred million per one gram; and the zeolite powder is clinoptilolite with particle size of 180 meshes. The water purifying agent has the advantages of improving water quality, conducting the function of oxidation, ammoniation, denitrification, dephosphorization, sulfurization, nitrogen fixation and the like, constructing and maintaining good ecological water environment, preventing and treating diseases, enhancing the anti-disease capacity of animals bred in the pond and improving the survival rate. The water purifying agent has a reasonable formula, is simple to prepare and has obvious application effect.

The reagent, pharmaceutical formulation, kit, and methods of the invention provides a new approach for treating pancreatic cancers. The invention provides the use of Na+e / K+-ATPase inhibitors, such as cardiac glycosides (e.g. ouabain and proscillaridin, etc.), either alone or in combination with other standard therapeutic agents (chemo- or radio-therapies, etc.) for treating pancreatic cancers. The subject Na+ / K+-ATPase inhibitors, such as cardiac glycosides, including bufadieneolides or their corresponding aglycones (e.g., proscillaridin, scillaren, and scillarenin, etc.), especially in oral formulations and / or solid dosage forms containing more than 1 mg of active ingredients.

The reagent, pharmaceutical formulation, kit, and methods of the invention provides a new approach to treat refractory cancers using Na+ / K+-ATPase inhibitors, such as cardiac glycosides, including bufadienolides or their corresponding aglycones (e.g., proscillaridin, scillaren, and scillarenin, etc.), especially in oral formulations and / or solid dosage forms containing more than 1 mg of active ingredients.

The invention provides a microbiological agent for aquaculture, which is prepared from the following constituents: bacillus subtilis 35-40%, photosynthetic bacterium 15-20%, nitrated bacterium 10-15%, lactic acid bacteria 0.1-1%, zeolite powder 24-39%, the preparation has the functions of oxidization, ammonization, anti-nitrification, de-phosphor, sulfidization and nitrogen fixation.

The invention provides a pig breeding method and relates to the technical field of breeding. The pig breeding method includes the steps of (1), pig breeding at the lactation stage, (2), pig breeding at the nursing stage, (3), pig breeding at the fattening stage, (4) management of pig houses, (5) daily stocking, and (6) prevention and control of diseases. Since standardized breeding of pigs is carried out by the pig breeding method, pig growth environments, feeds and the like are checked strictly, the pigs are bred at different stages and especially are fed with creep feed and fodder together at the lactation stage and the nursing stage, and weaning sensitivity of piglets is avoided. Meanwhile, pigs are fed with customized fodder at different stages of growth on the basis of nutrition according to need, the fodder is added with traditional Chinese medicine components which increase pigs' growth rate, have special health care function to pigs and guarantee pork quality, and accordingly economic benefit is increased.

The invention discloses four-season laying pigeon healthcare sand which mainly contains the following components: seashell pieces, medium-grain sand, calcium hydrophosphate, wood carbon powder, salt, yeast powder, red mud, composite trace elements, prague red, gentiana scabra, andrographis paniculata powder, licorice powder, lysine, methionine, composite vitamins, vitamin E and glucose. By adopting the four-season laying pigeon healthcare sand disclosed by the invention, the stress reaction capability of laying pigeons in hot or cold seasons can be improved, and diseases can be prevented. In addition, the production indexes such as the hatchability and the laying rate of laying pigeons are increased.

The invention discloses a balance training device and a using method thereof. The balance training device comprises a training treadmill, a supporting platform and a control center. The training treadmill is provided with a conveying belt. The balance training device further comprises a pressure sensor. The supporting platform is a six-freedom-degree parallel robot platform, is connected with the training treadmill and used for supporting the training treadmill and achieving movement of the training treadmill in six degrees of freedom. The control center is used for controlling the training treadmill and the supporting platform. The balance training device has the advantages that the balance training device is simple in structure, convenient to operate and high in safety coefficient, the whole feedforward can be finished in the device, balance training is stressed, a true movement environment is simulated, the training becomes difficult from simple and proceeds in an orderly way and step by step, the training cost is reduced, training objects are ordinary balance function dysfunction people to apoplexy dyskinesia patients and the like, and the balance training device is of great significance for alleviating social economic burden and making a balance training system enter families and has wide market prospects.

The invention relates to a protein-saving compound feed for young megalobrama amblycephalas and a preparation method of the protein-saving compound feed. The feed is mainly prepared from the following raw materials: 3-5% of fish meal, 17-22% of soybean meal, 10-15% of rapeseed meal, 10-15% of cottonseed meal, 8-10% of peanut meal, 3-5% of whole-milk extruded soybean, 5-8% of whole-milk vegetable seed, 5-8% fermented cottonseed meal, 3-5% of corn lee protein, 8-10% of wheat bran, 8-10% of wheat shorts, 1-2% of alpha-starch, 0.05-0.1% of bile acid and salt emulsifying agent, 0.015-0.03% of glycyrrhetinic acid, 1% of monocalcium phosphate and 1% of compound-premix for intensively-cultured fishes. The preparation method comprises the following steps of: stirring the raw materials in a stirring machine and introducing steam to prepare grains with the grain size of 1-2mm, and then, dewatering and cooling to the room temperature. By using the protein-saving compound feed for the young megalobrama amblycephalas, provided by the invention, the problem of unbalanced nutrition of the compound feed in the current culture of the young megalobrama amblycephalas is solved, the physical condition of the of the young megalobrama amblycephalas is improved, the growth speed of the young megalobrama amblycephalas and the feed utilization ratio are increased, and the feed production cost and the pollution to a water body in the culture process can be reduced.

A method whereby the blood pressure metabolism in an individual showing evidence of dysregulation is improved when that person receives an appropriate oral administration of (−)-hydroxycitric acid. The potassium salt of (−)-hydroxycitric acid is a preferred form of the compound, followed by the sodium salt, then by the amide and other derivatives of the acid. The regulation of blood pressure levels over any given period of time may be improved with a controlled release form of (−)-hydroxycitric acid. Controlled release can be used to provide a sustained and modulated amount of the active to the body as desired and therefore regulate the use of the compound as a hypotensive agent.

The invention discloses a formula of a feed of young meat wild pheasants in an earlier stage. The feed comprises the following constituents in parts by weight: 40-45 parts of corns, 16-24 parts of wheat, 15-22 parts of bean pulp, 7-11 parts of cabbage caterpillar meal, 5.2-6.5 parts of wheat bran, 4.4-5.8 parts of Chinese trumpet creeper powder, 3.5-5.5 parts of cottonseed hull fungus chaff, 2-4 parts of rapeseed meal, 1-2 parts of mountain flour, 1.2-2.4 parts of silkworm excrement, 1.5-2 parts of bone meal, 1-2 parts of yeast protein powder and 1.5-2.5 parts of modified zeolite particles. The feed is free from antibiotics, capable of meeting other nutritional needs, except for water, of the young meat wild pheasants, reasonable in formula, high in utilization rate, less in nutritional waste, beneficial to resource utilization, energy conservation and emission reduction, capable of protecting the environment, good in palatability, high in feed reward, and capable of achieving a feed-weight ratio of about 1.65:1 of pheasants of 14 days old; the feed can increase the survival rate of the young pheasants, the used raw materials are readily available, and the slaughtering weight of the pheasants of 120 days old can be improved by about 14.0%, thus obviously improving economic benefits.

The present invention relates to the production of chemical species in bacterial host cells. Particularly, the present invention provides for the production of chemical species in Escherichia coli (E. coli) host cells that functionally express engineered P450 enzymes.

The invention discloses an ecological restoration agent for an aquaculture water area, and relates to the technical field of pesticide compounding. The restoration agent consists of the following components in parts by weight: 100 to 200 parts of compound bacteria, 100to 200 parts of sodium humate, 660 to 800 parts of amino acid fertilizer water powder and 0.5 to 1.5 parts of compound sodium nitrophenolate. According to the ecological restoration agent disclosed by the invention, after the microorganism preparation is added into a water body, effects of oxidization, ammoniation, denitrification, phosphor-resolving, vulcanization, nitrogen fixation and the like are brought into play; organic substances such as excrements of aquaculture animals, remaining feed, animal and plant remians and the like are quickly decomposed, so that concentration of ammonia nitrogen and nitrite in the water body can be effectively reduced; and decomposed salts of the organic substances provide nutrition for growth and reproduction of unicellular alga, so that photosynthesis of the unicellular alga is guaranteed, dissolved oxygen in the water body is improved, and therefore, a good ecological water environment is built and kept.

The invention discloses a method for preparing lining material by organism colliquefaction, including the following steps: (a) organism pseudomonad suspending liquid up to the standards is put into a plastic can; (b) lining textile material is put into the plastic can to be soaked for 48 hours in the ratio that 1kg organism pseudomonad suspending liquid soaks 1-2 meters of the lining textile material when the water temperature of the organism pseudomonad suspending liquid is 20-28 DEG C and the room temperature is 25 DEG C, so as to lead the organism bacteria suspending liquid to form even and stable colony substance system; (c) the soaked penetrative lining textile material is naturally dried for 24 hours at room temperature of 15-30 DEG C, is roasted in an oven at 40 DEG C for 12 hours, and is made into the lining material containing organism. The lining material of the invention contains substances which can degrade pathogenic bacteria and decompose odor substance hidden in shoe cavity, thus achieving antibacterial and deodorant effect.

The invention discloses a formula of a feed of laying hens in the middle of an egg laying period. The feed comprises the following constituents in parts by weight: 40-50 parts of corns, 30-40 parts of wheat, 10-15 parts of peanut cake, 4-8 parts of caramel dregs, 3-6 parts of barley grass powder, 1.5-2.5 parts of spray-dried animal blood cells, 2-3 parts of eel bone meal, 2-3 parts of modified zeolite particles, 3-5 parts of coconut kernel powder, 2.5-4.5 parts of cucumber seed powder and 2-3 parts of three-worm meal. The feed disclosed by the invention completely meets the nutrition needed by laying hens in the growth stage in the middle of an egg laying period, adequately exerts the laying performance of the laying hen and the functions of the feed, has a high feed reward, is low in feeding cost, promotes the growth and laying of the laying hen, and achieves a laying rate of more than 90%; eggs are good in quality, deep in yolk colour and high in economic benefits.

The present invention relates to a penaeus vannamei compound feed which includes the following raw materials in parts by mass: schizochytrium limacinum meal 15-20 parts, fish meal 20-25 parts, shrimp shell powder 2-4 parts, cuttlefish powder 2-4 parts, peanut meal 10-15 parts, soybean meal 15-20 parts, flour 15-20 parts, complex vitamins 0.3-0.4 part, choline chloride 0.3-0.4 part and zeolite powder 2-3 parts. The replacement of part of fish meal with the schizochytrium limacinum meal reduces the feed costs; The addition of the schizochytrium limacinum meal enables the amino acids of the feed to be more balanced and complementary, therefore improving the feed efficiency; the schizochytrium limacinum meal is rich in active substances which can enhance the immune function of the penaeus vannamei, prevent the occurrence of diseases, reduce drug use in shrimp farming, improve the survival rate and growth rate of the penaeus vannamei. The schizochytrium limacinum meal contains DHA, significantly reduces or completely doesn't require the addition of fish oil, reduces the excessive reliance on fish meal and fish oil, and the marine fish resources are protected, at the same time the feed cost is reduced and the shrimp farming benefit is improved.

The invention discloses a formula of a feed of laying hens at age of 9-18 weeks in a growth period. The feed comprises the following components in parts by weight: 40-55 parts of corns, 20-30 parts of broken rice, 5-10 parts of rapeseed meal, 10-15 parts of wheat middling, 5-10 parts of plasma protein powder, 4-7 parts of yolk powder, 2-5 parts of distillers dried grains with soluble, 1.8-2.6 parts of chrysanthemum meal, 2-3 parts of burnt malt powder, 3-5 parts of pomegranate bark powder, 2.5-4.5 parts of bagasse and 1.6-2.2 parts of modified zeolite particles. The feed is reasonable in formula, rich in nutrition and high in palatability, the feed intake of the laying hens is increased, the waste of the feed is avoided, the breeding cost is reduced, rapid growth of the laying hens is promoted, the immunity of the laying hens is improved, the diseases of the laying hens are reduced, veterinary medicines such as antibiotics are not needed, dug residues are avoided, and the feed is safe and reliable.

The invention discloses a composition for improving skin stress response and promoting probiotics balance and a forming method. The composition is prepared from an artemisia annua leaf extract, a lactobacillus and eriodictyon californicum fermentation product extract, alpha-glucan oligosaccharide, carnosine and 1,2-pentanediol, wherein the concentration of the artemisia annua leaf extract is between 5% and 80%; the concentration of the lactobacillus and eriodictyon californicum fermentation product extract is 5% to 80%; the concentration of the alpha-glucan oligosaccharide is between 5% and 80%; the concentration of the carnosine is between 5% and 80%; the concentration of the 1,2-pentanediol is between 5% and 80%. Not only can the problem of skin fragility caused by deficiency of stratumcorneum and injuries be alleviated, but also the damage to the skin barrier caused by external stimuli can be solved; by combining various components, the skin can immediately improve cell stress response per self after being damaged to resist external irritation and damage, so that use feeling is good, the effect is fast, the preparation method is simple, and the composition is suitable for large-scale production and gives no burden to the skin.

The invention discloses an astronaut long flight anti-fatigue chewable tablet and a preparation method thereof. The chewable tablet is prepared from 30%-50% of pine nut protein powder, 4%-6% of blueberry freeze-dried powder, 2%-4% of wolfberry powder, 3%-5% of kiwi powder, 3%-5% of indigo fruit powder, 3%-5% of Schisandra fruit powder, 1%-2% of glutamine, 8%-15% of beta-cyclodextrin, 2%-5% of buckwheat starch, 10%-15% of xylitol, 2%-4% of citric acid and 5%-10% of fructooligosaccharides. The method is characterized in that pine nut protein is used as raw materials, and the chewable tablet with anti-fatigue effect is prepared on the basis of ensuring the nutritional balance on the ratio of the raw materials. The size of the tablet is designed according to the size of the mouth, to make the tablet easy to eat, good in taste and the like. The tablet can be used for space station astronauts, aviation pilots, field troops, navigation, submarines and other activities, can also be used for emergency relief, special forces, travel, overtime working and other people, to supplement consumed energy substance of the body in time, thereby rapidly relieving fatigue and restoring strengths, relieving mental fatigue, and improving the endurance and work efficiency in the fatigue state.

The invention discloses a crop physiology resistance inducer and a preparation method. The crop physiology resistance inducer is prepared from nano SiO2, nano CaCO3, heteroauxin, abscisic acid, humic acid, monopotassium phosphate and distilled water according to certain ratio. The preparation method comprises the following steps: (1) taking nano SiO2, nano CaCO3, heteroauxin, abscisic acid, humic acid, monopotassium phosphate and distilled water for standby application; (2) weighing the raw materials respectively according to the mass percent of the preparation amount, dissolving nano SiO2 and nano CaCO3 with ethyl alcohol respectively, mixing the solutions, after certain period of time, adding heteroauxin and abscisic acid, adding distilled water for dissolution, uniformly stirring, performing ultrasonic treatment, adding humic acid and monopotassium phosphate, adjusting the pH value with hydrochloric acid, and adding distilled water for constant volume to obtain the crop physiology resistance inducer. According to the invention, the formula is reasonable, the application is convenient, the resistance of crops to drought, low temperature, hard light and other adverse situations can be effectively induced, and high and stable yield of the crops can be ensured; the preparation method is practical, simple and convenient to operate, stable in ingredient dispersion, ecological and environment-friendly, free of environmental pollution, and convenient to popularize and apply.

The invention discloses a production formula of a premix for rabbits. The premix comprises the following components of garlicin, salinomycin sodium, diclazuril, colistine sulfate, bacitracin zinc, oxidized choline, AD3 powder, vitamin E powder, vitamin B1, vitamin C, vitamin B6, vitamin B2, vitamin B12, folic acid, taurine, biotin, niacin, vitamin K3, potassium, aspartame, prebiotic, yeast powder, methionine, lysine, cupric sulphate, zinc sulfate, ferrous sulfate, manganese sulfate, cobalt dioxide, sodium selenite, calcium iodate, calcium carbonate, astragalus membranaceus, rhizoma coptidis, phellodendron, radix scutellariae, costus roots, atractylodes rhizomes, dried orange peel, gypsum powder, cystine and threonine. Through the adoption of the production formula disclosed by the invention, various stress reactions of the rabbits can be effectively increased, the immunity and the disease resistance of organisms are strengthened, the healthy growth of the rabbits is promoted, and the skin and the hair of the rabbits are bright, so that the feed conversion ratio is increased.

The invention belongs to the technical field of preventing and control of harmful algae blooms, and particularly relates to a modified clay system for controlling harmful algae blooms in a culture water body. The modified clay is prepared from the following components in parts by weight: 10 to 50 parts of inorganic aluminum salt, 1 to 20 parts of tannin and 50 to 90 parts of clay minerals; in theuse process, the composite modified clay is pre-mixed with seawater to form a uniform turbid suspension; then, the turbid suspension is sprayed to the surface of the algae bloom at certain concentration, so as to reach the effect of quickly eliminating the excessive algae bloom organisms in the water body. The composited modified clay has the characteristics that the sources of materials are wide,the operation is simple, convenient and rapid, the efficiency is high, and the like.

The invention discloses a Liriodendron hybrids LhMKK2 gene, expression protein of the Liriodendron hybrids LhMKK2 gene and application of the liriodendron hybrids LhMKK2 gene. The nucleotide sequence is showed in SEQID NO.1 and the amino acid sequence is showed in SEQID NO.2. On the basis of the completely established somatic embryogenesis system of the Liriodendron hybrids and the fact that part of the transcriptome data is already obtained, the full length of the Liriodendron hybrids LhMKK2 gene, through the adoption of homology-based cloning, is obtained and is named as LhMKK2. Through gene expression analysis, that the Liriodendron hybrids LhMKK2 gene is widely expressed in plants and is involved in the growth and development of plants, and the adversity stress response process are proved; through functional analysis of the gene, it is discovered that the overexpression LhMKK2 gene is capable of enhancing resistance of plants to salt stress response, influencing the growth and development of plants and providing theoretical basis for stress resistance molecular breeding of Liriodendron hybrids and can be further widely used in adversity resistance stress of plants.

The invention relates to application of a methyl-jasmonate-containing compound in citrus canker. Effective components of the methyl-jasmonate-containing compound are composed of Zhongshengmycin and methyl jasmonate, wherein the weight ratio of Zhongshengmycin to methyl jasmonate is (3-20):1. According to the application of the methyl-jasmonate-containing compound in citrus canker, Zhongshengmycin to methyl jasmonate are compounded according to the specific weight ratio, the methyl-jasmonate-containing compound thus has obvious synergistic effects, the pesticide effect can be significantly improvded, the use amount of the single agent of either Zhongshengmycin or methyl jasmonate is easily reduced, the generation of resistance of bacteria to Zhongshengmycin is delayed, and the life cycle of Zhongshengmycin in antibiotic pesticides is prolonged.

The invention relates to a feed additive for increasing geese liver weight and content of unsaturated fatty acids, belonging to the technology field of livestock production, which is a novel feed additive for increasing geese liver weight and content of unsaturated fatty acids. The feed additive comprises vitamin C 50-200 g, vitamin E 6-7.2 g, Euthyrox 1.5-2 g, and pharmaceutical starch or glucose as adjuvant 800-938 g. The feed additive has prominent effect in increasing liver weight and content of unsaturated fatty acids; and the geese liver weight is increased by 39.45%, the content of abdominal fats is decreased by 0.1%, and the content of unsaturated fatty acids is increased by 4.6%. The feed additive has the advantages of high efficiency, low toxicity, low drug residues, fulfillment of environmental friendliness requirement for meat products, good safety, and low cost. The feed additive can also enhance immunity of geese, and can be stored at room temperature in a dark, sealed and moisture-proof environment for 3 years.

The invention relates to a feed phagostimulant for piglets and a preparation method of the feed phagostimulant. The phagostimulant is prepared from the following raw materials in parts by weight: 20-25 parts of cane sugar, 20-25 parts of glucose, 8-12 parts of citric acid, 6-10 parts of succinic acid, 15-20 parts of folium artemisiae argyi, 10-15 parts of pericarpium citri reticulatae, 10-15 parts of hawthorn, 8-12 parts of coptis chinensis, 6-10 parts of rheum officinale, 4-7 parts of liquorice, 3-6 parts of clove, 3-6 parts of mint, 2-5 parts of medicated leaven, 2-5 parts of cinnamon, 1-3 parts of vitamin A, 1-3 parts of vitamin C, 1-3 parts of vitamin K and 1-3 parts of lysine. The preparation method comprises the following steps: grinding the materials into fine powder, and granulating by a granulator, thereby obtaining the feed phagostimulant. The feed phagostimulant prepared by the method disclosed by the invention is matched with piglet feed, the stress response of the piglets can be effectively improved, and the food consumption of the piglets is increased, so that the survival rate of the weaned piglets is improved. The raw material source is safe, the breeding cost can be effectively reduced, and the economic benefits of raising households are increased.

The invention discloses an injection of compound micironomicin sulfate, its preparation method and application. the injection comprises (by weight part) micironomicin sulfate injection 1-20, chlorpheniramine maleate 0.1-1, and dexamethasone sodium phosphate 0.01-1. the preparation method comprises heating 50% water for injection to 40-50deg.C, dissolving each components, regulating pH to 3.5-6.5 with hydrochloric acid or sodium hydroxide, and adding water for injection to 1000. The invention has the advantages of rational formulation, reduced drugfastness, and shortened withholding period. It can enhance therapeutic effect, improve swinish immunity, increase swinish body weight; and can be used for treating mycoplasmal pneumonia of pig.

The invention discloses a triple inactivated vaccine used for porcine circovirus-3, porcine parvovirus and swine influenza and a preparation method thereof. The present invention first discloses the triple inactivated vaccine for the prevention and treatment of porcine circovirus syndrome, porcine parvovirus disease and swine influenza. The vaccine comprises: an inactivated antigenic solution of porcine circovirus-3 Cap protein, an inactivated antigenic solution of porcine parvovirus, an antigenic solution of porcine influenza virus and a vaccine adjuvant. The invention further discloses a method for preparing the triple inactivated vaccine, and the method comprises: mixing inactivated antigenic solutions together, uniformly mixing the mixed solutions with the vaccine adjuvant, and performing emulsification. The preparation method of the triple inactivated vaccine of the invention is simple, the vaccine has a high titer content and is convenient and quick for immunization. The triple vaccine provided by the invention has better safety, achieves "one shot with three preventions", avoids adverse reactions caused by multiple vaccination, reduces breeding cost, reduces the immunizationtimes, and can also effectively reduce the stress response of animals and improve the welfare treatment for animals.

Methods and compositions are provided to improve nitrogen use efficiency in plants or plant parts, increase carbon fixation in a plant or plant part, increase grain yield or biomass production of the plant, and / or increase the stress tolerance of the plant. The compositions and methods of the invention modulate these various phenotypes by modulating the level of at least one Dof (for DNA binding with one finger) polypeptide having a Dof domain or a biologically active variant or fragment of a Dof domain.