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69 results about "Phellodendron" patented technology

Phellodendron, or cork-tree, is a genus of deciduous trees in the family Rutaceae, native to east and northeast Asia. It has leathery, pinnate leaves and yellow, clumped flowers. The name refers to the thick and corky bark of some (but not all) species in the genus.

Herbal acne-removing composition as well as preparation method and application thereof

The invention relates to a herbal acne-cleaning composition as well as a preparation method and application thereof, and belongs to the technical field of cosmetics. The invention relates to a herbal acne-removing composition. The composition comprises the following components in parts by weight: 1-3 parts of honeysuckle flower extract, 4-6 parts of mangnolia officinalis bark extract, 0.1-1 part of dandelion extract and 2-5 parts of fermentation extract, a fermentation strain used in the fermentation extract is lactobacillus fermentum, the preservation number of the lactobacillus fermentum is CGMCC No.21381, and fermentation substrate powder comprises amur cork powder and white willow bark powder. The herbal acne-removing composition disclosed by the invention has a remarkable acne-removing effect, and is mild and non-irritant.
Owner:GUANGZHOU BAIYOUJIA BIOTECHNOLOGY CO LTD

Traditional Chinese medicine composition and traditional Chinese medicine preparation for promoting blood circulation and removing swelling

The traditional Chinese medicine composition is prepared from the following raw material medicines in parts by mass: 5 to 10 parts of cortex phellodendri, 5 to 10 parts of radix scutellariae, 5 to 10 parts of radix notoginseng, 5 to 10 parts of melastoma dodecandrum lour, 8 to 15 parts of herba lycopi, 8 to 15 parts of rhizoma alismatis, 8 to 15 parts of herba lycopodii, 12 to 18 parts of semen coicis, 1 to 3 parts of borneol, 135 to 150 parts of beewax and 390 to 400 parts of sesame oil. The She nationality characteristic medicinal material melastoma dodecandrum serves as a core component, the Qi and blood theory of traditional Chinese medicine is combined, multiple blood circulation promoting and stasis removing medicinal materials are combined, the comprehensive treatment effects of promoting blood circulation to remove swelling, regulating Qi to dissipate blood stasis and stopping bleeding and relieving pain are jointly achieved, the red, swollen and heat pain symptoms in the acute stage of fracture and sprain can be remarkably relieved, and the curative effect is good. The traditional Chinese medicine composition has the action trend of reducing local exudation and preventing swelling persistence, and has a practical clinical external treatment value for promoting early functional recovery of wounds.
Owner:JINGNING SHE AUTONOMOUS COUNTY PEOPLES HOSPITAL (COUNTY MEDICAL COMMUNITY)

Traditional Chinese medicine composition for preventing or treating prostatitis and preparation method and application thereof

InactiveCN121550362AAntipyreticAnalgesicsSalvia miltiorrhizaInflammatory swelling
The invention provides a traditional Chinese medicine composition for preventing or treating prostatitis and a preparation method and application thereof, and belongs to the technical field of health care medicines. The traditional Chinese medicine composition is prepared from the following components: semen plantaginis, herba taraxaci, radix sophorae flavescentis, cortex phellodendri, radix salviae miltiorrhizae, radix et rhizoma rhei, radix rehmanniae praeparata, fructus ligustri lucidi, semen cuscutae, herba cistanche, fructus lycii extract, longan extract, membrane of hen egg, fructus ziziphi jujubae extract, honey and rice fermentation filtrate. The traditional Chinese medicine composition is in a liquid dosage form prepared by a process including fermentation treatment. The traditional Chinese medicine composition prepared by the invention can relieve prostate tissue edema of a prostatitis model rat in a dose-dependent manner and reduce a prostate wet weight index, so that the traditional Chinese medicine composition has a certain improvement effect on prostate tissue hyperplasia and inflammatory swelling caused by chronic abacterial prostatitis.
Owner:XINXIANG JIYOUTANG BIOTECHNOLOGY CO LTD

External use medicine composition for clearing heat, removing swelling and resolving stasis, and application and preparation method thereof

This invention provides a topical medicine composition for clearing heat, reducing swelling, and resolving blood stasis in the acute phase, along with its application and preparation method, belonging to the field of traditional Chinese medicine formulation technology. This topical medicine composition for clearing heat, reducing swelling, and resolving blood stasis in the acute phase consists of the following raw material components in parts by weight: 5-8 parts raw Phellodendron bark, 2-5 parts borneol, 8-12 parts red peony root, 4-8 parts Panax notoginseng tablets, 4-6 parts stir-fried ground beetle, 2-4 parts prepared myrrh, 2-4 parts prepared frankincense, 5-8 parts prepared Arisaema, 8-12 parts Liquidambar formosana, 8-12 parts Angelica dahurica, 8-12 parts peppermint, and 8-12 parts Trichosanthes kirilowii. This topical medicine composition for clearing heat, reducing swelling, and resolving blood stasis in the acute phase selects traditional Chinese medicinal materials with relatively weak blood-activating effects, which can avoid the risk of increased bleeding and swelling during acute use, achieving safe and effective early intervention for ankle or other injuries in the acute phase, thereby shortening the patient's recovery time.
Owner:THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIV OF TRADITIONAL CHINESE MEDICINE (ZHEJIANG XINHUA HOSPITAL)

Lime-alum-containing external liquid for astringing sores and preparation method thereof

The invention relates to the technical field of traditional Chinese pharmacology, and particularly discloses an external liquid containing lime and alum for astringing sores and a preparation method of the external liquid. The external liquid containing lime and alum for healing sores is prepared from the following raw materials: lime, alum, water, a thickening agent, a cortex phellodendri extract, carbonized sanguisorba root powder, borneol and a pH regulator. The preparation method comprises the following steps: S1, preparing lime milk; s2, preparing an alum solution; s3, mixing reaction; s4, performing curing treatment; s5, blending; s6, refining: filtering the mixture obtained in S5, adding borneol and ethylparaben into the filtrate before filtering, and uniformly stirring to obtain the external liquid for healing sore. The external liquid containing lime and alum for healing sores can be used for treating various skin injuries such as skin ulcers, wounds, burns, eczema and postoperative wounds, and has the advantages of efficient astringency and hemostasis, antisepsis and anti-inflammation, promotion of wound healing, good system stability, comfort in use and high safety.
Owner:刘灿

Fermented traditional Chinese medicine composition for preventing and treating viral diarrhea of piglets as well as preparation method and application of fermented traditional Chinese medicine composition

The invention relates to a fermented traditional Chinese medicine composition for preventing and treating piglet viral diarrhea as well as a preparation method and application thereof, and relates to the technical field of livestock breeding. The feed is prepared by taking traditional Chinese medicine components as basic raw materials and adding probiotics for fermentation, and the traditional Chinese medicine components comprise the following raw materials in parts by weight: 0.5-1.5 parts of cardamine violifolia dry powder, 5-15 parts of Chinese pulsatilla root, 10-20 parts of coptis chinensis, 10-20 parts of golden cypress, 10-20 parts of ash bark, 4-8 parts of turmeric, 6-10 parts of pumpkin seeds and 4-8 parts of a ginkgo leaf extract feed additive. Through cooperation of multiple components, the immunity and antioxidant functions of the body are enhanced, the structural integrity of the intestinal tract is maintained, piglet diarrhea caused by PEDV infection is effectively relieved, and growth and development of the piglet are promoted; local specialty crops are selected as medicines, and theoretical basis and practical reference are provided for deep processing of local genuine medicinal materials and PED prevention and control.
Owner:ENSHI VOCATIONAL & TECH COLLEGE

Traditional Chinese medicine extract with folliculitis treatment effect, preparation method and prepared antibacterial shampoo

The invention provides a traditional Chinese medicine extract with a folliculitis treatment effect, a preparation method of the traditional Chinese medicine extract and prepared bacteriostatic shampoo, and belongs to the technical field of daily necessities. The traditional Chinese medicine extract is prepared from the following raw materials in parts by mass: 5 to 20 parts of rhizoma coptidis, 5 to 20 parts of cortex phellodendri, 5 to 20 parts of radix scutellariae, 5 to 20 parts of vinegar frankincense, 5 to 20 parts of vinegar myrrh, 5 to 20 parts of radix et rhizoma rhei, 5 to 20 parts of rhizoma polygoni cuspidati, 5 to 20 parts of radix stemonae and 5 to 20 parts of herba taraxaci. By optimizing the compatibility and extraction process of a traditional Chinese medicine formula and combining the modern preparation technology, the invention aims to provide a traditional Chinese medicine hair washing therapeutic agent which is efficient in permeation, long-acting in bacteriostasis, safe, mild and strong in cleaning power, so as to overcome the defects of current chemical hair washing products in the field of folliculitis treatment.
Owner:BEI CHUANG KAIYUAN (CHENGDU) PHARMACEUTICAL TECHNOLOGY CO LTD

Taxus baccata gel

PendingCN122272723ADiseaseLymphatic vessel
The invention patent is titled "Dragon and Cypress Gel," belonging to the pharmaceutical category. The main components of Dragon and Cypress Gel are: Phellodendron bark, earthworm, dragon's blood, Oldenlandia diffusa, Sophora flavescens, and Bletilla striata. In recent years, research on cervicitis and cervical lesions has shown good results using external treatments of traditional Chinese medicine. Vaginal cervical medications are characterized by high local drug concentration, low dosage, and safety and effectiveness, receiving high clinical evaluation. The vagina and cervix have abundant capillaries and lymphatic vessels, and lack clearly defined nerve endings, resulting in minimal pain stimulation for patients during administration. This makes it an effective drug release site for specific diseases such as cervicitis and vaginitis. Traditional Chinese medicine gels are a novel type of external preparation of traditional Chinese medicine. They are made by dissolving or uniformly dispersing traditional Chinese medicine in a gel. These gels adhere tightly to the treatment site for a relatively long time, exhibiting good bioadhesion, and are simple to prepare. It is suitable for use on skin, mucous membranes and cavities. It not only avoids the first-pass effect of enzymes and acids in the gastrointestinal tract that exists in oral administration, but also reduces the adverse reactions of drugs. It has the characteristics of good spreadability, non-greasy feeling, easy to wash off, good transdermal absorption, and comfortable use.
Owner:TAIYUAN YIYUAN ANFANG MEDICAL SERVICES CO LTD

Preparation process and quality inspection method of eczema cream

The preparation process of the eczema cream comprises the following steps: S1, raw material pretreatment: coarsely crushing calcined calamine; removing impurities from cortex phellodendri, coarsely crushing, and removing impurities from indigo naturalis for later use; mixing the three components, performing superfine grinding, and sieving with a 100-mesh sieve to obtain a medicinal powder raw material; s2, substrate preparation: melting and stirring beeswax and sesame oil at 85-90 DEG C, and cooling to obtain a transparent substrate; s3, mixing and forming: mixing the medicinal powder raw materials and the transparent matrix according to the mass ratio of (2.07-1): 2.13, uniformly stirring at 85-90 DEG C, cooling, solidifying, sterilizing and packaging to obtain the eczema cream. According to the standardized preparation process and the quality inspection method of the eczema cream, by optimizing superfine grinding parameters, a matrix ratio and a quality control system, stable production and quality controllability of the eczema cream are achieved, and technical support is provided for preparation conversion.
Owner:JINGMEN HOSPITAL OF TRADITIONAL CHINESE MEDICINE

A traditional Chinese medicine composition for treating acute or chronic gouty arthritis, and a preparation method and use thereof

The present application belongs to the field of traditional Chinese medicine, and relates to a traditional Chinese medicine composition for treating acute or chronic gouty arthritis, and a preparation method and application thereof. One of the purposes of the present application is to provide a traditional Chinese medicine composition comprising lotus leaf, cortex fraxini, atractylodes, smilax glabra, phellodendron, plantago seed and licorice. In the prescription, the lotus leaf is the monarch herb for clearing heat and resolving summer-heat, raising clear yang and cooling blood to stop bleeding; cortex fraxini, phellodendron and atractylodes are the ministerial herbs to strengthen the heat-clearing and dampness-drying effect of the monarch herb; plantago seed is diuretic and detoxicant, smilax glabra is detoxicant and dampness-removing and joint-activating, and licorice is heat-clearing and detoxicant and pain-relieving, which can not only relieve symptoms, but also has mild medicinal property. The whole prescription has the effects of removing dampness and discharging turbidity, removing blood stasis and heat, and relieving pain, and is effective in treating acute or chronic gouty arthritis with symptoms of joint redness and swelling, fever, pain or tenderness, and limited activity, or accompanied by systemic fever, thirst and yellowish urine.
Owner:成都诺和晟欣生物医药有限公司

A traditional Chinese medicine composition for treating insomnia based on a modification of Zhang Zhongjing's Wumei Pill

ActiveCN120241942BCoptisMilk protein
This invention provides a composition comprising: 5-15 parts by weight of dried plum, 10-20 parts by weight of cinnamon twig, 10-20 parts by weight of ginseng, 3-8 parts by weight of angelica root, 5-15 parts by weight of asarum, 10-30 parts by weight of dried ginger, 5-15 parts by weight of Sichuan pepper, 5-15 parts by weight of phellodendron bark, 3-8 parts by weight of coptis root, 20-40 parts by weight of bitter wine, 20-30 parts by weight of japonica rice, 10-20 parts by weight of honey, 3-8 parts by weight of lily bulb, 40-60 parts by weight of polygonum multiflorum stem, 40-60 parts by weight of monkey head mushroom, 3-8 parts by weight of polygala root, and 5-15 parts by weight of poria cocos (a traditional Chinese medicine composition). Further, the composition comprises: 20-40 parts by weight of hydrolyzed milk protein, 20-40 parts by weight of fish collagen peptide, and 20-40 parts by weight of soybean peptide (a biological product). This invention also provides pharmaceutical preparations (especially pills) comprising the above composition, biological products, and methods for preparing the same. The composition has a significant effect on improving sleep and has broad application prospects.
Owner:HANGZHOU YUAN HEALTH MANAGEMENT CO LTD

Composition comprising complex extract of coptis japonica, phellodendron chinensis, scutellaria baicalensis, gardenia jasminoides, and rheum palmatum

The present invention relates to a composition comprising a complex extract of Coptis japonica, Phellodendron Chinensis, Scutellaria baicalensis, Gardenia jasminoides, and Rheum palmatum. The composition was confirmed to: reduce the levels of blood cholesterol, blood lipids, and blood LDL-cholesterol in patients with dyslipidemia; reduce systolic blood pressure without affecting diastolic blood pressure and pulse rate in patients with hypertension; reduce the level of pulse wave velocity (PWV), which is an indicator of arteriosclerosis, in patients with atherosclerosis, and inhibit the recurrence rate for up to 5 years in patients with cerebral infarction. Accordingly, the composition is provided as a therapeutic agent for dyslipidemia, hypertension, arteriosclerosis, or cerebral infarction. In particular, the composition is made into an encapsulated form rather than conventional decoctions, to reduce the content of geniposide, which is reported as a side effect component, and thus an optimal composition which maintains efficacy against dyslipidemia and does not cause side effects is provided.
Owner:PANACURA INC

A traditional Chinese medicine composition, a biocontrol preparation and application in the field of prevention and treatment of pearl leaf spot nematode disease

The application belongs to the technical field of biocontrol preparation, and particularly relates to a traditional Chinese medicine composition, a biocontrol preparation and application in the field of pearl plant leaf spot nematode disease prevention and treatment. The leaf spot nematode disease is a main disease and pest of pearl plant planting, and there is no effective prevention and treatment method at present. The application provides a traditional Chinese medicine composition, which comprises wolfberry, leigongteng, peppermint, phellodendron, boerhaavia diffusa and chamomile. Water extracts of the above-mentioned medicinal ingredients can effectively reduce the number of nematodes in soil and improve the disease resistance of pearl plants when used for pearl plant irrigation. The research results of the application are helpful for restraining the occurrence of pearl plant leaf spot nematode disease through biological prevention and control means, and provide theoretical guidance for the development of pearl plant green industry.
Owner:HUANGSHAN UNIV +1

An antibacterial hydrogel made from traditional Chinese medicine for ulcer healing, its preparation method and application

PendingCN122075610AImprove pathological structureNo side effectsAntibacterial agentsAerosol deliveryPolyvinyl alcoholScrophularia
This invention belongs to the field of traditional Chinese medicine technology, specifically relating to a herbal antibacterial hydrogel for ulcer healing, its preparation method, and its application. The hydrogel is composed of a herbal composition and a matrix. The herbal composition includes dandelion, angelica, scrophularia, forsythia, phellodendron, atractylodes, angelica dahurica, and raw licorice. The matrix contains chitosan, polyvinyl alcohol, water, and glacial acetic acid. The effective components of the herbal medicine are extracted by decoction, concentrated, and freeze-dried to obtain a freeze-dried powder. This powder is then mixed with a chitosan aqueous solution and cross-linked using a liquid nitrogen cyclic freezing method to form the hydrogel. This invention closely addresses the core pathogenesis of diabetic foot ulcers—"blood stasis, dampness, and heat (toxin)"—allowing the various herbs to synergistically exert their effects of clearing heat and detoxifying, promoting blood circulation and removing blood stasis, drying dampness and astringing sores, and nourishing blood and promoting tissue regeneration. The chitosan matrix endows the hydrogel with good biocompatibility, antibacterial properties, and sustained-release drug properties, which can improve the microenvironment of the ulcer wound, inhibit inflammatory responses, and promote granulation tissue growth, effectively promoting the healing of skin sores such as diabetic foot ulcers, and has broad application prospects.
Owner:SHANDONG UNIV OF TRADITIONAL CHINESE MEDICINE

A three-dimensional interplanting method and system for phellodendron, gardenia and rosemary

The present application relates to the technical field of medicinal plant cultivation, and particularly relates to a three-layered vertical interplanting method and system for phellodendron, gardenia and rosemary, which comprises site selection, land preparation, construction of a whole garden space coordinate system, standardization of upper phellodendron planting, precision interplanting of middle gardenia based on crown shadow characteristics, interplanting of lower rosemary pollination drainage belt suitable for gardenia flowering period, supporting layered targeted water and fertilizer management, root zone and light environment collaborative regulation, secondary metabolite collaborative green pest control, and staged harvesting whole-process management and control. The system is equipped with four linkage modules to realize whole-process standardized closed-loop management and control. The present application realizes spatial and time sequence collaborative adaptation of three different ecological niche medicinal crops, effectively solves the problem of interplanting competition for light and fertilizer, and improves the land utilization rate and the standardization level of ecological planting of Chinese medicinal materials.
Owner:HUNAN FENGYUN AGRICULTURAL SCIENCE & TECHNOLOGY DEVELOPMENT CO LTD

Pharmaceutical composition for treating infantile eczema as well as preparation, preparation method and application thereof

The invention relates to a pharmaceutical composition and a preparation for treating children eczema, and a preparation method and application thereof, and belongs to the technical field of traditional Chinese medicines. The pharmaceutical composition for treating children eczema is prepared from rhizoma smilacis glabrae, fructus kochiae, cortex phellodendri, radix sophorae flavescentis and dried alum, and has the effects of tonifying spleen, removing dampness, clearing away heat and toxic materials, dispelling wind and arresting itching; the rhizoma smilacis glabrae is a monarch drug for clearing away heat and toxic materials The fructus kochiae has the effects of clearing heat, promoting diuresis, dispelling wind and arresting itching, the cortex phellodendri has the effects of purging fire, removing steam, detoxifying and treating sores, and the radix sophorae flavescentis has the effects of clearing heat, drying dampness and killing parasites to relieve itching; dried alum is used for astringing dampness and relieving itching. Compared with the existing medicine for treating infantile eczema, the medicine composition disclosed by the invention is good in treatment effect, simple in preparation process and convenient to carry and use; and side effects caused by the use of chemicals can be avoided.
Owner:SHANGHAI TRADITIONAL CHINESE MEDICINE BIOTECHNOLOGY CO LTD

Traditional Chinese medicine compound composition as well as preparation method and application thereof

The invention provides a traditional Chinese medicine compound which is prepared from the following raw material medicines: rhizoma smilacis glabrae, rhizoma dioscoreae septemlobae, semen coicis, rhizoma curcumae longae, herba taxilli, radix salviae miltiorrhizae, cortex phellodendri, rhizoma acori graminei, plantain herb, rhizoma atractylodis macrocephalae, wine-treated rhubarb, radix angelicae pubescentis, bran-fried rhizoma atractylodis and vinegar-treated rhizoma corydalis, and also provides application of the traditional Chinese medicine compound composition in medicines for treating gout and gouty nephropathy. In addition, the invention also provides a preparation method of the sustained-release granule of the compound composition, which comprises the following steps: firstly, preparing the raw medicinal materials into a traditional Chinese medicine fluid extract, then adding the filler into the traditional Chinese medicine fluid extract, stirring to form a soft material, passing the soft material through a swinging granulator, and drying to obtain a medicine-containing pill core; and putting the pill cores into a fluidized bed, laterally spraying the slow-release coating solution, drying, and sieving to prepare the slow-release granules. The prepared traditional Chinese medicine formula sustained-release granules can release 90% or above within 8-10 hours, have a good constant-speed sustained-release characteristic, can meet the clinical requirement of 1-2 times of administration every day, and have good clinical application prospects and market value.
Owner:WANGJING HOSPITAL OF CHINA ACAD OF CHINESE MEDICAL SCI

Bletilla striata hemorrhoid cream and preparation method thereof

The invention discloses bletilla striata hemorrhoid cream and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine, the bletilla striata hemorrhoid cream comprises the following raw materials by weight: 10-30 parts of bletilla striata, 10-30 parts of pseudo-ginseng, 10-30 parts of sophora fruit, 10-30 parts of rheum officinale, 10-30 parts of phellodendron and 10-30 parts of borneol. The haemorrhoids ointment prepared by the invention highlights the effects of promoting tissue regeneration and stopping bleeding, treats both symptoms and root causes, is pure herbal and easy to absorb, can perform targeted detoxification and stasis dissipation, detumescence and tissue regeneration promotion, blood circulation activation and cooling on an affected part, has a good treatment effect and is not easy to relapse, meanwhile, the preparation process is simple, the raw materials only need to be mixed, wall-broken and crushed and then prepared into the ointment, and the method is simple, easy to control and suitable for popularization and application. The large-scale production can be realized.
Owner:戴巧兰

A traditional Chinese medicine composition for treating skin diseases and a preparation method thereof

PendingCN122643396APropolisPsoriasis universalis
This invention discloses a traditional Chinese medicine composition for treating skin diseases and its preparation method, belonging to the field of traditional Chinese medicine technology. It is made from the following raw materials in parts by weight: 8-12 parts of Phellodendron bark, 8-12 parts of Cnidium monnieri fruit, 8-12 parts of Dictamnus dasycarpus root bark, 8-12 parts of Stemona japonica root bark, 8-12 parts of alum, 8-12 parts of Carthamus tinctorius flower, 8-12 parts of dragon's blood, 8-12 parts of Panax notoginseng root bark, 8-12 parts of myrrh, 8-12 parts of frankincense, and 1-3 parts of propolis. This invention also provides an external preparation containing this composition and its preparation method. The preparation method includes pulverizing the raw materials, adding 60%-80% ethanol, soaking at 50-80℃ for 2-7 days, pressing, filtering, and allowing to stand, then collecting the supernatant. Pharmacological experiments show that the composition of this invention has significant antibacterial, anti-inflammatory, and antipruritic effects; clinical observations show a total effective rate of 80%-95% for psoriasis, eczema, rashes, pruritus, herpes, urticaria, and insect bite itching. The formulation of this invention is scientific, the process is stable, and the efficacy is definite, making it suitable for clinical application.
Owner:TIANJIN XINGQING TRADING CO LTD

Traditional Chinese medicine composition for ovary maintenance and application thereof

The invention relates to a traditional Chinese medicine composition for ovary maintenance and application thereof, and relates to the technical field of traditional Chinese medicines. The traditional Chinese medicine composition comprises the following components: eucommia ulmoides, fructus cnidii, witch hazel, radix sophorae flavescentis, saffron crocus, leonurus, eclipta alba, golden cypress, stiff silkworm, radix rehmanniae, radix scrophulariae, radix polygonati officinalis, semen cuscutae, salvia miltiorrhiza, radix puerariae powder, aloe, chrysanthemum and angelica sinensis. The traditional Chinese medicine composition is used for preparing the herbal medicine plant bag, various herbal medicines are used, and the traditional Chinese medicine composition can be used for maintaining ovary, treating female postpartum vaginal relaxation, repairing damaged elastic fibers, treating vaginal relaxation from inside to outside and diminishing inflammation, and has the characteristics of quick effect, good curative effect, convenience in use, nature, safety and no side effect.
Owner:GUANGXI GAOZAN HEALTH MANAGEMENT CO LTD

A method for preparing a metformin compound hypoglycemic oral solution

PendingCN122075608Asuppress original outputIncreased sensitivityOrganic active ingredientsMetabolism disorderMetformin hclOral solutions
This invention provides a method for preparing a metformin compound hypoglycemic oral solution, relating to the pharmaceutical field, comprising: step S1, pretreatment of traditional Chinese medicine components; step S2, enzymatic hydrolysis of the first group of traditional Chinese medicine components; step S3, supercritical extraction; step S4, preparation of mixed traditional Chinese medicines; step S5, preparation of inclusion complex; step S6, compound formulation; and step S7, post-processing. This method synergistically combines extracts from seven traditional Chinese medicines—bitter melon, phellodendron bark, astragalus root, kudzu root, rehmannia root, ginseng, and privet fruit—with metformin hydrochloride to form a metformin compound hypoglycemic oral solution, balancing the synergy, safety, and stability of traditional Chinese and Western medicines, thereby improving hypoglycemic effects while reducing the incidence of gastrointestinal adverse reactions to metformin.
Owner:CHONGQING CONQUER PHARML

Externally-applied traditional Chinese medicine ointment for treating radioactive skin injury and preparation method of externally-applied traditional Chinese medicine ointment

The invention discloses an externally-applied traditional Chinese medicine ointment for treating radioactive skin injury and a preparation method thereof, and relates to the technical field of externally-applied traditional Chinese medicines. The externally-applied traditional Chinese medicine ointment is prepared from the following components in parts by weight: traditional Chinese medicine raw materials, targeted active ingredients and functional auxiliary materials, the traditional Chinese medicine raw materials comprise 30 parts of borneol, 30 parts of talc, 10 parts of radix sophorae flavescentis, 10 parts of fructus cnidii, 5 parts of frankincense, 5 parts of myrrh, 6 parts of fructus forsythiae, 10 parts of calamine, 10 parts of rheum officinale, 15 parts of mirabilite and 10 parts of cortex phellodendri. According to the external application traditional Chinese medicine ointment, classic traditional Chinese medicines such as borneol and talc are compatible and optimally proportioned, the effects of pungent and fragrant movement, heat clearing, pain relieving, inflammation resisting and itching relieving of the borneol are utilized, the effects of heat clearing, dampness astringing, sore astringing and skin barrier protecting of the talc are combined, intervention is achieved on core symptoms such as erythema, pruritus and erosion of acute radiodermatitis, and the traditional Chinese medicine ointment is safe and reliable. Different from an existing traditional Chinese medicine external preparation with a single effect, adverse reactions of western medicine hormones and growth factors are also avoided.
Owner:SHANXI PROVINCE CHINESE MEDICINE RESEARCH INSTITUTE

A whitening toothpaste containing natural plant extracts and its preparation method

This invention discloses a synergistic anti-caries oral care composition and its application. The composition comprises: (a) a single-domain antibody targeting the Streptococcus mutans surface protein PAc; (b) a plant extract complex containing kudzu root extract and phellodendron bark extract; and (c) gallic acid liposomes. This invention also provides a toothpaste containing this composition and a method for its preparation. Experiments have shown that the single-domain antibody can specifically bind to and disturb the Streptococcus mutans biofilm, increasing cell membrane permeability and synergistically promoting the entry of plant extracts into the cell to exert a bactericidal effect, achieving a clearance rate of over 98% for mature biofilms. Through formulation and process optimization, this invention solves the stability problem of antibodies in toothpaste; the product retains more than 90% of its activity after two years of storage at 25°C. The composition and product provided by this invention have the advantages of highly efficient removal of mature biofilms, synergistic effect, safety with low damage, and excellent stability, and have broad application prospects in the field of oral care.
Owner:GUANGZHOU BIYAN COSMETICS CO LTD

Preparation process of a compound traditional Chinese medicine granule preparation for veterinary use

This application relates to the technical field of important veterinary preparations and discloses a preparation process for a compound traditional Chinese medicine granule preparation for veterinary use, including the following steps: (1) extracting dandelion, indigo leaf, isatis root, honeysuckle, licorice, patchouli, and gypsum with water to obtain an aqueous extract; adding scutellaria and phellodendron to the residue after water extraction and extracting with alcohol to obtain an alcohol extract; combining the extracts and concentrating to obtain a clear extract; (2) first mixing hydroxypropyl-β-cyclodextrin and sulfobutyl ether-β-cyclodextrin to obtain a mixed cyclodextrin solution, adding glycyrrhizic acid for pre-inclusion to form a glycyrrhizic acid-cyclodextrin pre-inclusion complex; then adding the obtained clear extract to continue inclusion to form an inclusion complex suspension; (3) mixing the inclusion complex suspension with pharmaceutical excipients, granulating and drying to obtain the final product. This application can improve the inclusion rate of baicalin and berberine and improve storage stability.
Owner:FUJIAN SHENGWEI BIOTECHNOLOGY CO LTD

A bacteriostatic sheng muscle traditional Chinese medicine composition for chronic wounds and application thereof

This invention belongs to the field of medical and nursing care products technology, specifically relating to a traditional Chinese medicine composition for chronic wounds that promotes antibacterial and tissue regeneration, and its application. The raw materials for this composition include Paris polyphylla, dragon's blood, frankincense, myrrh, rhubarb, Phellodendron bark, calamine, pearl powder, Oroxylum indicum, sappanwood, and Rosa laevigata leaves. When this traditional Chinese medicine combination is prepared into a topical ointment and applied to the wound, it possesses potent antibacterial, blood-activating, and tissue-regenerating effects, achieving simultaneous intervention at multiple stages. This improves wound healing and treatment outcomes, addressing issues such as bacterial resistance, insufficient regenerative capacity of modern dressings, and insufficient early-stage antibacterial and anti-inflammatory effects in existing chronic wound treatments. This provides a safe, effective, and economical new treatment option for clinical practice.
Owner:SHANGHAI YANGPU CENT HOSPITAL

A traditional Chinese medicine composition for treating scald and a preparation method thereof

ActiveCN121466250BHas rapid-acting analgesic effectNo further damage will occurHydroxy compound active ingredientsAerosol deliveryGanoderma lucidumArnebia
The present application relates to the technical field of traditional Chinese medicine composition, and particularly to a traditional Chinese medicine composition for treating scald and a preparation method thereof, and provides a traditional Chinese medicine composition for treating scald, which comprises: honeysuckle stem, lotus leaf, kadsura coccinea, one mouth clock, rehmannia glutinosa, turmeric, phellodendron, raw sanguis draconis, angelica tail, radix violae, ganoderma lucidum, plum slice, natural white beeswax and camellia oil. The scald treatment medicine prepared from the traditional Chinese medicine composition has the advantages of rapid analgesia, no adhesion after dressing change, promotion of wound healing, short healing period, scar repair function and stable quality.
Owner:BEIHUA UNIV

Traditional chinese medicine composition for treating tinnitus

PendingCN122272716ADrying mouthRhizome
This invention relates to the field of traditional Chinese medicine (TCM) technology, and particularly to a TCM composition for treating tinnitus. Its ingredients include: vinegar-processed turtle shell, stir-fried jujube seed, anemarrhena rhizome, phellodendron bark, rehmannia root, white peony root, poria cocos, fleeceflower root vine, scutellaria barbata, oldenlandia diffusa, stir-fried atractylodes macrocephala, prunella vulgaris, and cicada slough. The TCM composition of this invention exhibits significant multi-dimensional beneficial effects in treating tinnitus. Compared with Western medicine treatments, it avoids the side effects such as low blood pressure, dizziness, drowsiness, and dry mouth associated with vasodilators and antidepressants, and overcomes the drawbacks of physical therapy, which only temporarily relieves symptoms and cannot cure the condition. It has the advantages of holistic conditioning and fewer side effects, providing a safe, effective, and comprehensive treatment plan for tinnitus patients, and has high clinical application value and promotional significance.
Owner:DONGFANG HOSPITAL BEIJING UNIV OF CHINESE MEDICINE

Application containing acne-removing traditional Chinese medicine composition and preparation method thereof

The invention discloses an application containing an acne-removing traditional Chinese medicine composition and a preparation method of the application, and belongs to the technical field of traditional Chinese medicine acne-removing patches. The application sequentially comprises a non-woven fabric layer, an ointment layer and a polyethylene layer from top to bottom. The ointment layer comprises a first ointment layer and a second ointment layer; the first ointment layer is prepared from the following components in parts by mass: 6 to 12 parts of fructus forsythiae extract, 2 to 4 parts of cortex phellodendri extract, 3 to 6 parts of honeysuckle flower extract, 2 to 5 parts of herba taraxaci extract, 0.5 to 1.5 parts of radix gentianae extract, 0.5 to 1 part of radix ginseng extract and 1 to 4 parts of herba centellae extract; the second ointment layer is prepared from the following components in parts by mass: 0.5 to 2.5 parts of borneol, 6 to 8 parts of water-soluble chitosan and 3 to 6 parts of modified nano silicon dioxide. According to the application, grease generated by acnes can be adsorbed, redness and swelling can be eliminated, skin barriers can be repaired, relapse can be prevented, and both symptoms and root causes of the acnes can be treated.
Owner:SHANDONG HANFANG PHARMA

Composite bactericide of nanoscale silver ions and traditional Chinese medicine extract

The invention discloses a nano-scale silver ion and traditional Chinese medicine extract composite bactericide, and relates to the technical field of composite bactericides, the nano-scale silver ion and traditional Chinese medicine extract composite bactericide comprises 30 g of sophora flavescens, 10 g of phellodendron, 30 g of glabrous greenbrier rhizome, 15 g of common cnidium fruit, 10 g of oriental wormwood, 10 g of honeysuckle, and 20 g of silver ions with a silver content of 5000 ppm, and 1000 ml of the nano-scale silver ion and traditional Chinese medicine extract composite bactericide is prepared. Silver ions are positively charged cations formed when metal silver loses one or more electrons and comprise Ag < 1 + >, Ag < 2 + > and Ag < 3 + > which exist in the form of an aqueous solution, and the preparation method of the nano-scale silver ion and traditional Chinese medicine extract composite bactericide comprises the following steps that S1, six traditional Chinese medicines including radix sophorae flavescentis, cortex phellodendri, rhizoma smilacis glabrae, fructus cnidii, herba artemisiae scopariae and honeysuckle flowers are taken and extracted with water for use. The traditional Chinese medicine composition has a good killing effect on vibrio, mould, aeromonas hydrophila and the like through the combination of the traditional Chinese medicine and the silver ions, compared with a single preparation, the dosage of the traditional Chinese medicine composition is better than that of a single preparation, and the traditional Chinese medicine composition is better in killing bacteria and inhibiting drug resistance of viruses and is higher in cost performance.
Owner:JIANGSU JINSHIDUN PHARMACEUTICAL CO LTD

Traditional Chinese medicine composition for treating Alzheimer disease as well as preparation method and application of traditional Chinese medicine composition

PendingCN121513110ANervous disorderPlant ingredientsDiseaseHypericum perforatum
The invention relates to the technical field of preparation and application of traditional Chinese medicine compositions, and particularly discloses a traditional Chinese medicine composition for treating Alzheimer's disease and a preparation method and application thereof. The traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 3-9 parts of ginseng, 3-10 parts of morinda officinalis, 6-12 parts of dogwood, 3-10 parts of rhizoma acori graminei, 3-10 parts of polygala tenuifolia, 3-6 parts of rhodiola rosea, 3-6 parts of China rose, 2-3 parts of hypericum perforatum, 3-6 parts of saussurea involucrate, 9-15 parts of cortex lycii radicis, 3-12 parts of golden cypress and 1-5 parts of agilawood. The traditional Chinese medicine composition provided by the invention accords with the traditional Chinese medicine treatment concept of tonifying deficiency and filling marrow, inducing resuscitation and soothing nerves, dredging collaterals and eliminating evil, and tonifying spleen and assisting transportation, not only can relieve damage of neurons, but also can reverse alzheimer disease related disorder signal channels in neuronal cells, microglial cells and astrocytes.
Owner:BEIJING CAPITALBIO PHARMA CO LTD