244 results about "Berberis empetrifolia" patented technology

A method of treating non-insulin dependent diabetes mellitus comprising the step of providing a composition comprising a predetermined amount of berberine and a predetermined amount of catalpol, wherein said berberine and said catalpol are major active ingredients of said composition. The composition may further comprise a predetermined amount of oleanolic acid as another active ingredient. The berberine is obtained from natural herbs selected from the group of Berberis, Chelidonium, Stephniz, Coptis, Phellodendron, and Ziziphus, the catalpol is obtained from natural herbs selected from the group of Rehmannia, Verbascum, Panulownia, Glubularia and Adonis, and the oleanolic acid is obtained from natural herbs selected from the group of Olea, Swertia, Astrantia, Lonicera and Beta.

The present invention relates to a nutritional product, dietary supplement or pharmaceutical composition for the treatment of acne and related skin disorders. The invention also relates to a composition having a combination of ingredients such that it reduces symptoms associated with acne and related skin disorders. The invention relates to such a composition containing a variety of vitamins, minerals and one or more herbal medicine sources. In one preferred embodiment, the vitamins, minerals and one or more herbal medicine sources are present in an amount such that its mechanism of action is through inhibition of the growth of Propionobacterium acnes (P. acnes) and the inhibition of lipogenesis of sebum production. In another preferred embodiment, the invention contains a Vitamin A source to normalize keratinoid maturation, proliferation and turnover of skin cells. In another preferred embodiment, the invention further contains at least one of a Vitamin E source or Selenium. In another preferred embodiment, the invention further contains at least one of a Vitamin B6 source, a Pantothenic Acid source, Zinc or any active salt, and Chromium or any active salt. In another preferred embodiment, the invention further contains any one or more of an herbal source of Berberis aquifolium (Oregon grape root), Barberis vulgaris (barberry), Hydrastis Canadensis (goldenseal), or other herbal source of the compound berberine. The present invention also relates to a method of administering a therapeutically effective amount of the combination of ingredients for the treatment of acne and related skin disorders.

The invention discloses preparation and quality detection method of compound prescription cortex phellodendri chinensis fluid. The quality detection method comprises the identification of forsythia fruit, cortex phellodendri, honeysuckle and dandehon herb, the checking of lonicerae flos, and the content determination of forsythin and berberine hydrochloride. According to the determination method, spots with the same colors are formed in a qualified test article thin-layer chromatogram and in corresponding positions of a reference substance thin-layer chromatogram, and negative control is interference-free, and the method is good in selectivity, simple and accurate. The checking method of lonicerae flos adopts a high performance liquid chromatography, is good in specificity, and can distinguish the situation that lonicerae flos is adopted in the compound prescription cortex phellodendri chinensis fluid to pretend honeysuckle flower to charge material. The content determination of forsythin and berberine hydrochloride is good in linear relation and high in recovery test accurancy, has good repeatability and stability, can accurately and strictly detect the quality of the compound prescription cortex phellodendri chinensis fluid, and guarantees a high quality standard level of the compound prescription cortex phellodendri chinensis fluid.

The invention, which belongs to the technical field of characteristic chromatograms, provides an HPLC characteristic chromatogram of the rhizome of Chinese goldthread and a construction method and application thereof, and a quality detection method of the preparation of rhizome of Chinese goldthread. The HPLC characteristic chromatogram includes eight characteristic peaks; and the peak 8 being a berberine peak is used as a contrast peak. The relative retention time of all characteristic peaks is as follows: the relative retention time of the peak I is 0.095; the relative retention time of thepeak 2 is 0.359; the relative retention time of the peak 3 is 0.526; the relative retention time of the peak 4 is 0.551; the relative retention time of the peak 5 is 0. 581; the relative retention time of the peak 6 is 0.653; the relative retention time of the peak 7 is 0.888; and the relative retention time of the peak 8 is 1.000. The relative retention time and relative peak areas of all peaks are within a 5% range. The characteristic chromatogram can be used for controlling the quality of the preparation of rhizome of Chinese goldthread; and the operability is high.

The invention relates to a method for observing microscopic structures inside plant roots, which is capable of effectively solving the problem of utilizing a microscope to clearly observe the structures inside the plant roots. The method comprises the steps of digging out the plant roots, washing, shearing the plant roots into small sections, fixing the plant roots by methanol, and then embedding by a sepharose solution, cooling, condensing, trimming into small blocks, after freehand section, placing the small blocks into distilled water in a container, performing lactic acid clearing, covering, dyeing via berberine or fluorescein, bleaching by the water, performing poststaining via toluidine blue O or sarranine O, bleaching by the water, performing water seal, observing and photographing via an inverted fluorescence microscope, and obtaining a clear image. The method can be used for observing the microscopic structures inside the plant roots, thereby being effectively used for the research on classification, auxanology, ecology and physiology of medical plants. The method disclosed by the invention has the advantages of simple method, easiness in operation, low cost, low working capacity, high success rate, and good effect, thereby being capable of being used for the research on morphological anatomy of the roots. The method is simpler and more effective for the thinner root sections of the plants.

The invention relates to a micro-emulsion for killing Monilinia fructicola and a preparation method thereof. The micro-emulsion for killing the Monilinia fructicola consists of effective components, a solvent, an emulsifier, an antifreeze and water, wherein the effective components are berberine and salicylic acid. The solvent is preferably ethanol with volume percentage of over 95 percent. The emulsifier is preferably Tween 80. The antifreeze is preferably a glycol water solution with a concentration of 5 percent g / mL. The preparation method comprises the steps of: taking and mixing the berberine and the salicylic acid, adding the mixture into the solvent, and heating to dissolve the mixture to obtain an effective component solution; adding the emulsifier into the solution, dissolving the emulsifier under ultrasonic conditions, heating the obtained solution in water bath, and stirring the obtained solution to obtain an effective component emulsion; and adding the emulsion into the antifreeze, heating the mixture in water bath, and stirring the mixture to obtain the micro-emulsion for killing the Monilinia fructicola. The micro-emulsion can strongly inhibit the Monilinia fructicola, has broad-spectrum antibacterial property, and has the advantages of stability, high efficiency and low cost at the same time.

The invention discloses a wettable powder capable of preventing and treating fruit and vegetable brown rot and aphid as well as a preparation method thereof. The wettable powder comprises the components by weight: 20-30% of active components, 55-60% of carrier, 7-13% of wetting agent and 2-7% of dispersant; wherein the active components are a Szechwan chinaberry fruit extract product and berberine. The preparation method comprises the following steps: 1)mixing the Szechwan chinaberry fruit extract product and berberine in proportion, performing ultramicro-pulverization, passing through a sieve with 325 meshes to obtain the active components; 2)mixing the active components with a carrier, a wetting agent and a dispersant in proportion, performing ultramicro-pulverization, collecting powder after ultramicro-pulverization, performing spray drying, passing through the sieve with 325 meshes, and repeatedly operating until all the powder is passed through the sieve with 325 meshes to obtain the wettable powder. The wettable powder is capable of strongly inhibiting fruit and vegetable brown rot and aphid, and has the advantages of no toxicity, no pesticide residue, environmental protection, stabilization, high efficiency and low cost.

The invention discloses a natural feed additive and a preparation method thereof. The additive is prepared by taking berberine hydrochloride and astragalus polyose as raw materials and combining the raw materials according to a proper proportion. The natural feed additive has the advantages of having the capability of improving the immunity and disease resistance of animals, promoting the growth and development of the animals and increasing the productivity.

The invention discloses a method for detecting a medicinal oral preparation for treating irritable bowel syndrome. The medicinal oral preparation is mainly prepared from radix bupleuri, fried radix paeoniae alba, roasted rhizoma atractylodis macrocephalae, saposhnicovia divaricata, roasted fructus aurantii immaturus, roasted pericarpium citri reticulatae, fructus mume, coptis chinensis and honey-fried licorice root, as well as auxiliaries. The detection method comprises the following steps: carrying out thin-layer chromatography identification on roasted rhizoma atractylodis macrocephalae, roasted pericarpium citri reticulatae, roasted fructus aurantii immaturus, fructus mume and honey-fried licorice root in the oral preparation and detecting the content of paeoniflorin and berberine hydrochloride. The detection method is accurate and has high sensitivity, good repeatability and stable detection result, the quality of the medicinal oral preparation for treating irritable bowel syndrome can be effectively detected, and the standard of each detection item can guarantee the curative effect of the medicine.

The invention discloses a bactericidal composition containing berberine and tebuconazole. The bactericidal composition is prepared by compounding the active ingredients including berberine and tebuconazole in a mass ratio of (1 to 9)-(9 to 1). The bactericidal composition can be prepared into conventional dosage forms in the pesticide science, such as wettable powder, water dispersible granules, suspensions, microcapsule suspensions, granules or emulsion in water. The bactericidal composition has the advantages of high efficiency, little environmental pollution, capability of delaying the resistance of germs to drugs, and the like, and can be used for controlling diseases of various crops, especially rice bacterial leaf streak.

The invention discloses a marine fungus, novel skeleton meroterpenoid derivatives prepared from the marine fungus as well as a preparation method and application of the novel skeleton meroterpenoid derivatives. The marine fungus Aspergillus terreus GZU-31-1 is preserved in Guangdong Microbiological Culture Collection Center on December 17, 2019 and has a preservation number of GDMCC No:60789. Sixnovel skeleton meroterpenoid derivatives are separated from fermented liquid of the marine fungus, have novel structures and are capable of remarkably reducing the activity of triglyceride; particularly, when the concentrations of the compounds 1-5 are 2 microliters and 5 microliters, the content of triglyceride in cells is remarkably reduced; especially the lipid decreasing activity of the compound 1 at a concentration of 5 microliters is even superior to that of a positive control, namely berberine at the same concentration. The compounds provided by the invention have a great application value to lipid decreasing and can be prepared into lipid decreasing drugs for use.

The invention relates to a compound preparation used for controlling nutritional diarrhea of a weaned piglet. The compound preparation is prepared from Chinese pulsatilla root, flower of poplar, acalypha australis, geranium wilfordii, berberine hydrochloride and aloe or cactus extracts; and the compound preparation can be prepared into preparation in a form of powder. The compound preparation can be directly applied to the weaned piglet or uniformly mixed with feed for feeding, and also can be soaked with warm water and then taken with the liquid; the compound preparation shows great effect on controlling the nutritional diarrhea of the weaned piglet, and also can promote growing and improve the immunity of the organism.

The invention discloses a compound Chinese medicine extract preventing arteriosclerosis, comprising the following effective ingredients: dried alcohol, Beta-sitosterol, hexacosanoic acid, butenolide III, oleanolic acid, berberine, jateorhizine, coptisine, salvianic acid A, salvianolic acid B, ring-tetracosane, 9,12-octadecadienoic acid, 5,7-dimethoxy coumarin, specnuezhenide, ginsenoside Rb1 and Rg1, notoginsenoside R1, encommiol and the like. A preparation method of the extract is as follows: taking salvia miltiorrhiza, fructus ligustri lucidi, rhizoma coptidis, cirsium japonicum, eucommia bark, atractylodes macrocephala koidz, radix pseudo-ginseng and bergamot as raw materials, conducting C1-3 alcohol extraction and / or water extraction on a total extract, then extracting the total extract by organic solvents with different polarities so as to obtain all the effective ingredients, and finally mixing the effective ingredients so as to obtain the compound Chinese medicine extract preventing arteriosclerosis. As for the compound Chinese medicine extract, a large number of ineffective chemical ingredients are removed, so that the content of effective ingredients is improved greatly, the influence on product processing and preparation quality caused by the ineffective ingredients is reduced, the preparation process is stable, the product quality is controllable, and the mass production is facilitated.

The invention relates to a tolfenpyrad-containing pesticide composition for preventing and controlling nematodes, and an application thereof. The pesticide composition comprises an effective active component A and an effective active component B, the active ingredient A is tolfenpyrad, the active component B is selected from one of thiodicarb, monosultap, abamectin, fosthiazate, fluazaindolizine,fluensulfone, fluxapyroxad, trifluoro nematicide, Tioxazafen, phoxim, spirotetramat, dithiocyano-methane, berberine and carvacrol, and the weight ratio of the active component A to the active component B is 1:40 to 40:1. The pesticide composition disclosed by the invention has a relatively good prevention effect on crop root-knot nematodes, pine wood nematodes, cyst nematodes, stem nematodes and the like, and provides a preparation and an application mode which have a synergistic effect, are convenient to use, safe and efficient for preventing and controlling crop nematodes.

The invention discloses a plant source synergistic compound bactericide and an application thereof. The compound bactericide is prepared by the following steps: by taking berberine and emodin monomethyl ether as main components, adding the aids, and compounding to obtain the product. The dosage forms of the preparation refer to environment-friendly missible oil, microemulsion, aqueous solution or dissoluble liquid. The preparation comprises 0.1-20 percent of berberine, 0.1-20 percent of emodin monomethyl ether and the balance of aids. The compound bactericide does not contain any chemical pesticide component, is easy to degrade in the environment, does not have environmental pollution and residual toxins and is safe to the people, livestock and environment, and drug resistance is difficultly generated by pathogenic bacteria; the powdery mildew, gray mold, anthracnose, downy mildew, phytophthora root rot, brown rot, tea leaf blight and other agricultural diseases on melons, fruits, vegetables and tea trees can be controlled, and the compound bactericide has extremely high application and popularization values on melons, fruits, vegetables, tea, medicinal materials and other main agricultural and sideline products exported for earning foreign exchange and is an ideal novel pollution-free bactericide.

The invention relates to the technical field of medicines. The invention specifically discloses application of a Tibetan medicine composition in preparation of medicines and / or health products for preventing and / or treating metabolic diseases. The composition is characterized in that the metabolic diseases comprise hyperlipidemia, diabetes mellitus or complications caused by any one of the hyperlipidemia and the diabetes mellitus, and the active ingredients of the composition comprise at least two of turmeric curcumin, berberis bark total alkaloids, emblic total tannin and tribulus terrestristotal saponins. All the raw materials have a synergistic effect and achieve the effects of preventing and treating hyperlipidemia, diabetes mellitus and complications thereof, the medicine componentsare simplified while the curative effect is ensured, the dosage can be effectively reduced, side effects are avoided, and the safety is high.

The invention discloses a natural feed additive and a preparation method thereof. The additive is prepared by taking astragalus polyose, Saccharicterpenin, origanum oil and berberine hydrochloride as raw materials and combining the raw materials according to a proper proportion. The natural feed additive has the advantages of having the capability of improving the immunity and disease resistance of animals, promoting the growth and development of the animals and increasing the productivity.

The invention discloses a method for inspecting the quality of a haemorrhoids suppository. The method comprises steps of identifying and measuring the content, wherein the step of identifying comprises a step of identifying a thin-layer chromatography of Chinese galls in the haemorrhoids suppository, wherein a Chinese gall reference medicine material and a nutgall acid reference substance are taken as reference materials, and trichloromethane-ethyl formate-formic acid is taken as a developing solvent; the step of measuring the content comprises a step of detecting berberine in the haemorrhoids suppository, namely, measuring by adopting a high-performance liquid chromatography method taking a berberine reference substance as a reference material and a solution prepared from a acetonitrile-0.1% phosphoric acid solution (every 100ml of the solution contains 0.1g of sodium dodecyl sulfate) as a mobile phase. The method has the advantages of sensitivity, stability, reliability and the like, the defect that the thin-layer identification negative chromatography of scutellaria baicalensis can cause interference is effectively eliminated, a system is high in suitability, linear relation, precision degree, sample stability and repeatability and sample feeding recycling rate, and the quality of a medicine can be accurately reflected, so that the quality of the medicine can be effectively controlled.

The invention provides functional medicinal bait for improving quality of soft-shelled turtles. The functional medicinal bait is prepared from, by weight, 145-155 parts of rhizoma polygonati, 95-105 parts of codonopsis pilosula, 75-85 parts of prepared rehmannia roots, 65-75 parts of lycium barbarum, 48-52 parts of semen cuscutae, 48-52 parts of honeysuckle, 9-10.5 parts of berberine, 148-152 parts of beta-glucan, and 300-350 parts of selenium-enriched corn protein powder or 0.8-1.2 parts of selenium powder. The invention further provides a preparation method and feeding method of the functional medicinal bait for improving the quality of the soft-shelled turtles. The physique of the soft-shelled turtles can be remarkably improved, immunity is improved, the morbidity is reduced, and the survival rate is increased. The width and thickness of calipash can be increased, the content of delicious amino acid in muscles is greatly increased, the quality, taste, appearance and quality safety of the bred soft-shelled turtles are guaranteed, and the quality of the soft-shelled turtles and the composite economic results of breeding can be effectively improved.

The invention provides a content measuring method for four components in a Chinese medicinal composition. The Chinese medicinal composition consists of Chinese medicaments such as ginseng, dwarf lilyturf tuber, dogwood, root of red rooted salvia, sauted spina data seed, Chinese taxillus twig, red peony root, ground beetle, nardostachys root and the like. The Chinese medicinal composition is clinically used for treating arrhythmia. The content of paeoniflorin, content of loganin, content of berberine and content of salvianolic acid B in the Chinese medicinal composition are measured at the same time by adopting an efficient liquid phase method; and the method is simple, convenient and feasible, the measurement results are accurate and reliable, and the method can be used for evaluating the quality of the Chinese medicinal composition.

The invention discloses a bezoar supernatant composite and a preparation method of the bezoar supernatant composite. The bezoar supernatant composite comprises calculus bovis factitius, mint, chrysanthemum, schizonepeta spike, radix angelicae, the rhizome of chuanxiong, jasmine, goldthread, golden cypress, scutellaria baicalensis, rheum officinale, fructus forsythiae, the root of common peony, Chinese angelica, rehmannia, platycodon grandiflorum, liquorice, gypsum and borneol. The preparation method of the bezoar supernatant composite comprises the following steps of: smashing the calculus bovis factitius, the rheum officinale and the borneol to be used as medicine, and extracting the other crude medicines to be used as medicine. The invention is characterized in that the composite quality meets the following quality requirements: (1) in terms of berberine hydrochloride, the berberine content is not less than 0.406%; (2) the forsythin content is not less than 0..043%; and (3) the baicalin content is not less than 1.54%. The pharmaceutical effect of the bezoar supernatant composite medicine provided by the invention is obviously better than that of the composite which can not meet the requirement.

The invention discloses a biological insecticide for Chinese cabbage and a preparation method thereof. The biological insecticide for Chinese cabbage is composed of the following components with contents in percentage by weight: 5-12% of fresh ginger extract, 8-15% of garlic extract, 5-10% of sealwort extract, 4-12% of ailanthus peel extract, 7-12% of semen armeniacae amarae extract, 10-18% of saponin extract, 8-16% of white pepper extract, 4-10% of azadirachtin extract and 7-20% of berberis thunbergii extract.

The invention relates to a cutting propagation method of berberisthunbergii harlequin, and belongs to the technical field of plant propagation. The cutting propagation method comprises the following steps of (1) establishing a berberisthunbergii harlequin field cultivation female parent nursery; (2) transplanting female parent seedlings; (3) performing management and maintenance; (4) cutting spikes, inserting branches, and performing rejuvenation of female parents; (5) selecting proper propagation fields for establishing berberisthunbergii harlequin potting seedling production seedbeds; (6) immediately watering sufficient water, and performing management after cutting; (7) performing daily management; and (8) performing seedling stage management. The cutting propagation method of the berberisthunbergii harlequin can be adapted to climate and soil environment of China, rooting conditions are good, the rate of finished products achieves 90%, besides, the operation is simple, the propagation speed is high, and the cutting propagation method has good market prospects.

The invention discloses a kit for identifying cortex berberis origins. The kit contains a reagent for amplifying four gene segments containing nucleotide sequences shown as SEQIDNO: 3-6. The invention further discloses a method for identifying the cortex berberis origin. The kit and the method can effectively and accurately distinguish various origins of cortex berberis, and the identifying method is simple and stable, has the important significance on usage of standard cortex berberis and can effectively guarantee the quality of medicinal materials and a clinical curative effect, and the application prospect is good.

The invention discloses a brewing method of Chinese cinquefoil herb flavored date palm fruit wine. The Chinese cinquefoil herb flavored date palm fruit wine is prepared by taking Chinese cinquefoil herb and date palms as raw materials, and adding seeds of pepperweed, roots of farges decaisnea, roots of younghusband jerusalemsage, walnut kernels, liquorice roots, fructus sino podophylli, white silkworms, astragalus membranaceus, herb of alpine gentian, berberis kansuensis schneid, balanophora harlandii, donkey-hide gelatin and Chinese yams. According to the brewing method, nutritive value of the Chinese cinquefoil herbs and the date palms are sufficiently utilized; the Chinese cinquefoil herbs and the date palms are matched with traditional Chinese medicines to realize synergistic interaction, so that the Chinese cinquefoil herb flavored date palm fruit wine has the effects of preventing phlegm from forming and stopping coughing, and clearing away heat and toxic materials. The finished-product fruit wine is golden brown or light brown, and the finished product has a mellow, fresh and sweet mouth feel and a fragrant taste; the wine has both wine aroma and fruit aroma, and the discomfort of people with cough and excessive phlegm, caused by the fact that people smoke for many years, can be obviously improved after the wine is taken for a long period. The brewing method has a simple manufacturing process, is easy to realize, has remarkable economic value and can be used for carrying out large-scale production.

The invention discloses a pharmaceutical composition to prevent and treat diabetic nephropathy, characterized by being prepared from, by weight, 1-15 parts of common turmeric rhizome, 1-8 parts of bark of Berberis kansuensis, 1-15 parts of fruit of emblic leafflower and 1-8 parts of puncturevine caltrap fruit. The medicinal results of the four-herb turmeric decoction under different combination doses for rats with diabetic nephropathy are observed and are combined with principal component analysis to dig the optimal combination of the four-herb turmeric decoction that is effective in intervening early diabetic nephropathy; the clinical application of the decoction and development of new drugs are promoted.

The invention belongs to the technical field of pesticides, and particularly relates to a bactericidal composition for preventing and treating a rice bacterial leaf streak. The bactericidal composition for preventing and treating the rice bacterial leaf streak is formed by compounding effective components which are berberine and orysastrobin, wherein the mass ratio of the berberine to the orysastrobin is (1 to 20):(20 to 1). The bactericidal composition provided by the invention can be prepared into conventional dosage forms of wettable powder, a water dispersible granule, a suspending agent, a micro-capsule suspending agent, a granule or an aqueous emulsion and the like in agricultural pharmacology. The bactericidal composition provided by the invention has advantages of being high in efficiency and little in environment pollution and delaying the generation of the drug resistance of a germ, and the like. The bactericidal composition can be used for preventing and treating diseases of multiple crops, and particularly the rice bacterial leaf streak.

The present invention provides a kind of Chinese medicine composition for clearing away heat and toxic matter, drying damp and treating dysentery and its preparation process and application. The Chinese medicine composition has effective components prepared with berberine hydrochloride, celandine, Chinese pulsatilla and ash bark in certain weight proportion. It is prepared into oral liquid, tablet, capsule or granule. The present invention also provides the application of the Chinese medicine composition in preparing medicine for treating diarrhea and dysentery caused by dampness and heat in the large intestine.