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Bezoar supernatant composite and preparation method thereof

A technology of composition and bezoar, applied in the directions of drug combination, pharmaceutical formula, plant raw material, etc., can solve the problems of non-conformity, low content of active ingredients, large difference in preparation method, etc.

Inactive Publication Date: 2012-09-26
JIANGXI HERBI SKY CO LTD
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  • Summary
  • Abstract
  • Description
  • Claims
  • Application Information

AI Technical Summary

Problems solved by technology

Among them, Niuhuangshangqing pills are made of whole raw medicine powder, which contains a lot of medicinal fiber and low active ingredient content, which does not conform to the development trend of modern Chinese medicine; both Niuhuangshangqing capsules and Niuhuangshangqing tablets have extracted most of the medicinal materials in the prescription. , greatly increased the content of active ingredients, but the preparation methods of the two are quite different

Method used

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Examples

Experimental program
Comparison scheme
Effect test

Embodiment 1

[0074] Artificial bezoar 2.9g Mint 44.1g Chrysanthemum 58.8g Nepeta panicle 23.5g Angelica 23.5g Chuanxiong 23.5g Gardenia 73.5g Coptis 23.5g Phellodendron 14.7g Scutellaria baicalensis 73.5g Rhubarb 117.7g Forsythia 73.5g Red peony 23.5g Angelica 73.5g Rehmannia glutinosa 94.1 g bellflower 23.5g licorice 14.7g gypsum 117.7g borneol 14.7g

[0075] The above nineteen flavors, rhubarb, borneol, and artificial bezoar are crushed into fine powder, sieved, and set aside; peppermint, nepeta, angelica, chuanxiong, angelica, and chrysanthemum are distilled to extract volatile oils, and the distilled aqueous solution is filtered and collected for use; Slag and licorice, gardenia, red peony root, rehmannia root, platycodon grandiflorum, gypsum and other six medicinal materials, add 10 times the amount of water to decoct twice, each time for 1.5 hours, filter, and combine the filtrate; add 10 times the amount of water to extract Coptidis Rhizoma and Cortex Phellodendri twice , each time ...

Embodiment 2

[0095] Example 2 Capsules

[0096] Artificial bezoar 2.9g Mint 44.1g Chrysanthemum 58.8g Nepeta panicle 23.5g Angelica 23.5g Chuanxiong 23.5g Gardenia 73.5g Coptis 23.5g Phellodendron 14.7g Scutellaria baicalensis 73.5g Rhubarb 117.7g Forsythia 73.5g Red peony 23.5g Angelica 73.5g Rehmannia glutinosa 94.1 g bellflower 23.5g licorice 14.7g gypsum 117.7g borneol 14.7g

[0097] The above nineteen flavors, rhubarb, borneol, and artificial bezoar are crushed into fine powder, sieved, and set aside; peppermint, nepeta, angelica, chuanxiong, angelica, and chrysanthemum are distilled to extract volatile oils, and the distilled aqueous solution is filtered and collected for use; Slag and licorice, gardenia, red peony root, rehmannia glutinosa, platycodon grandiflorum, gypsum and other six herbs are decocted twice with 10 times the amount of water, each time for 1.5 hours, filtered, and the filtrates are combined; Coptidis and Cortex Phellodendri are extracted twice with 8 times the amo...

Embodiment 3

[0102] Artificial bezoar 2.9g Mint 44.1g Chrysanthemum 58.8g Nepeta panicle 23.5g Angelica 23.5g Chuanxiong 23.5g Gardenia 73.5g Coptis 23.5g Phellodendron 14.7g Scutellaria baicalensis 73.5g Rhubarb 117.7g Forsythia 73.5g Red peony 23.5g Angelica 73.5g Rehmannia glutinosa 94.1 g bellflower 23.5g licorice 14.7g gypsum 117.7g borneol 14.7g

[0103] The above nineteen flavors, rhubarb, borneol, and artificial bezoar are crushed into fine powder, sieved, and set aside; peppermint, nepeta, angelica, chuanxiong, angelica, and chrysanthemum are distilled to extract volatile oils, and the distilled aqueous solution is filtered and collected for use; Slag and licorice, gardenia, red peony root, rehmannia glutinosa, platycodon grandiflorum, gypsum and other six herbs are decocted twice with 10 times the amount of water, each time for 1.5 hours, filtered, and the filtrates are combined; Coptidis and Cortex Phellodendri are extracted twice with 8 times the amount of water , 2 hours each ...

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Abstract

The invention discloses a bezoar supernatant composite and a preparation method of the bezoar supernatant composite. The bezoar supernatant composite comprises calculus bovis factitius, mint, chrysanthemum, schizonepeta spike, radix angelicae, the rhizome of chuanxiong, jasmine, goldthread, golden cypress, scutellaria baicalensis, rheum officinale, fructus forsythiae, the root of common peony, Chinese angelica, rehmannia, platycodon grandiflorum, liquorice, gypsum and borneol. The preparation method of the bezoar supernatant composite comprises the following steps of: smashing the calculus bovis factitius, the rheum officinale and the borneol to be used as medicine, and extracting the other crude medicines to be used as medicine. The invention is characterized in that the composite quality meets the following quality requirements: (1) in terms of berberine hydrochloride, the berberine content is not less than 0.406%; (2) the forsythin content is not less than 0..043%; and (3) the baicalin content is not less than 1.54%. The pharmaceutical effect of the bezoar supernatant composite medicine provided by the invention is obviously better than that of the composite which can not meet the requirement.

Description

technical field [0001] The invention relates to the field of traditional Chinese medicines, in particular to a bezoar supernatant composition and a preparation method thereof. Background technique [0002] The 2010 edition of "Pharmacopoeia of the People's Republic of China" Instructions for Clinical Medication There are 5 strains of heat-clearing and purging gunpowder contained in the volume of traditional Chinese medicine preparations, and Niuhuang Shangqing Capsules (tablets and pills) belong to one of the strains. Niuhuang Shangqing Capsules (tablets, pills) have the effects of clearing heat and purging fire, dispersing wind and relieving pain, and are used for headache, dizziness, red eyes and tinnitus, sore throat, sore mouth and tongue, gum Swelling and pain, dry stool. Among them, Niuhuangshangqing pills are made of whole raw medicine powder, which contains a lot of medicinal fiber and low active ingredient content, which does not conform to the development trend of...

Claims

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Application Information

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Patent Type & Authority Applications(China)
IPC IPC(8): A61K36/804A61P29/00G01N30/02
Inventor 吴安明吴孔松严建良刘永祥
Owner JIANGXI HERBI SKY CO LTD
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