19 results about "Calculus bovis" patented technology

The invention belongs to the technical field of traditional Chinese medicine (Tibetan medicine), and particularly relates to a Tibetan medicine composition for treating new coronavirus infection and application of the Tibetan medicine composition. The invention discloses a Tibetan medicine composition for treating new coronavirus infection and application of the Tibetan medicine composition. The composition is prepared from the following components in parts by weight: 100 to 700 parts of fructus chebulae, 10 to 80 parts of radix aconiti lateralis, 10 to 60 parts of radix aucklandiae, 50 to 600 parts of rhizoma acori calami, 10 to 50 parts of Muslim myrrh, 0.01 to 50 parts of calculus bovis factitius and 0.01 to 50 parts of artificial musk. The composition can inhibit the mRNA expression of the N gene and the ORF1ab gene after the SARS-CoV-2 virus infects the Vero cell, so that the treatment on the novel coronavirus infection is realized.

The invention belongs to the technical field of biochemical pharmacy, and particularly relates to a compound bezoar composition, decoction piece type compound bezoar and a preparation method of the decoction piece type compound bezoar. The compound calculus bovis composition provided by the invention comprises 94-96% by mass of main agents and 8 kinds of calculus bovis intermediates, the mass content of the auxiliary agent is 4-6%, and the auxiliary agent is six commercially available finished product combined cholic acid. The bilirubin content of the bezoar intermediate used in the invention is increased by more than 30% and the yield is increased by more than 25% compared with the existing biochemical reaction process of oxgall. The DPPH free radical scavenging rate of the compound bezoar composition reaches 89.6% + / -2.1% and is increased by 25.7-36.9% compared with 58.3% + / -3.5% of a product prepared from ox bile, and through t inspection, p is smaller than 0.01 (n is equal to 5). Free cholic acid intervention is strictly prohibited, lithocholic acid addition is completely eradicated, and the composition has the advantages of being high in bilirubin content, high in oxidation resistance and high in biological activity and adapts to the physiological characteristics of the human body.

The invention discloses a traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and a preparation method of the traditional Chinese medicine composition, and belongs to the field of traditional Chinese medicine compositions for fading scars. 5 to 15 parts of a gel matrix; 10 to 25 parts of an oil phase component; 3-8 parts of an emulsifier and a thickener; and the balance of water. Wherein the active traditional Chinese medicine component consists of 1-5 parts of calculus bovis factitius, 1-3 parts of artificial musk, 3-10 parts of cowherb seed, 3-10 parts of golden cypress, 2-8 parts of frankincense and 2-8 parts of myrrh. The traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and the preparation method of the traditional Chinese medicine composition have the beneficial effects that the traditional Chinese medicine composition for inhibiting and fading scar hyperplasia and the preparation method of the traditional Chinese medicine composition are provided, all the medicines are combined to jointly achieve the effects of promoting blood circulation to remove blood stasis, dredging collaterals, removing stasis, resisting inflammation and promoting tissue regeneration and directly refer to the pathogenesis core of scar hyperplasia, and an oil-in-water (O / W) latex dosage form is adopted, so that the traditional Chinese medicine composition has the refreshing effect of gel and the moistening effect of cream, and is easy to coat and good in air permeability.

The invention discloses eye protection liquid and a preparation method thereof, and belongs to the technical field of traditional Chinese medicine external preparations. The eye protection liquid is prepared from a chrysanthemum extract, borneol, calculus bovis factitius, venenum bufonis, realgar, a mint extract, a pipewort extract, a feather cockscomb seed extract, a butterflybush flower extract, pearl powder and purified water according to a specific weight part ratio, and is prepared by soaking, distilling, filtering and filling. The traditional Chinese medicine composition can rapidly permeate into eyes and directly enter focus, can relieve and treat various eye diseases such as presbyopia, myopia, amblyopia, cataract and the like, has the effects of soothing liver and relieving depression, promoting blood circulation and dredging collaterals, tonifying kidney and nourishing yin, supplementing optic nerve nutrition and improving microcirculation around the eyes, has the total effective rate of 100% and the cure rate of 80-95%, and is free of side effects and drug resistance and convenient to use.

The utility model relates to the field of injectors, in particular to a bezoar strain injector with a leakage-proof design. Comprising a needle cylinder, a piston is installed on the inner wall of the needle cylinder, a needle head is installed at one end of the needle cylinder, an adjusting structure is arranged on one side of the piston and comprises a connecting block, the connecting block is fixedly connected with the piston, a connecting plate is fixedly connected to one side of the connecting block, and a sliding groove is formed in the upper surface of the connecting plate; a positioning block is slidably connected to the inner wall of the sliding groove, a fixing hole is formed in the upper surface of the positioning block, a fixing rod is slidably connected to the inner wall of the connecting plate, and a limiting plate is fixedly connected to one end of the fixing rod. The calculus bovis strain injector with the leakage-proof design has the advantages that the position of the piston can be effectively locked, the piston is prevented from moving due to external factors in the operation, transportation or storage process, the safety of strains is ensured, and the leakage phenomenon is avoided.

The invention discloses a compound paracetamol and amantadine hydrochloride capsule containing caffeine microcapsules, which relates to the technical field of medicines and comprises paracetamol, amantadine hydrochloride, calculus bovis factitius, pharmaceutic adjuvants and functional microcapsule units. The functional microcapsule unit has a three-layer structure: a core material taking caffeine and microcrystalline cellulose as a core, an ethyl cellulose controlled release layer and a quick release layer containing chlorpheniramine maleate. According to the structure, time sequence controlled release of drugs is achieved by synthesizing a polymer coating material, chlorpheniramine maleate is quickly released when encountering gastrointestinal fluid to quickly resist allergy, and caffeine starts to be slowly released after being effectively delayed to the intestinal environment, so that the time when the plasma concentration reaches the peak tends to be synchronous with the time when chlorpheniramine maleate reaches the peak; the drowsiness side effect can be effectively resisted.

The novel fixing frame comprises a bottom plate and side plates, the side plates are arranged on the left side and the right side of the bottom plate in a welded mode, the side plates are provided with handrails and second door plates, the handrails are arranged above the second door plates, hollow grooves are formed between the second door plates and the handrails, and the second door plates are arranged in the hollow grooves. The side plates are provided with limiting mechanisms matched with the hollowed-out grooves. The limiting mechanism comprises a sliding rail, a sliding block and a steel pipe, the sliding block is arranged on the sliding rail in a sliding mode, a clamp is welded to the sliding block, and the steel pipe penetrates through the clamp and the hollowed-out groove. The novel fixing frame for artificial cultivation of calculus bovis is simple in structure, practical in function and ingenious in design, and effectively solves the problem that an existing fixing frame is not provided with a side face door plate for an operation, and inconvenience is brought to the operation process.

A method for screening and efficiently cultivating bezoar strains belongs to the field of bezoar strain screening, and comprises the following steps: step 1, inoculating a culture medium with low-pathogenicity Escherichia coli for culturing, comparing and observing, picking out single colonies with good growth vigor for subculture, and preserving the strains after culture; 2, taking the primarily screened preserved strain, reviving in four regions of an LB solid culture medium by marking lines, selecting a single colony, putting the single colony into a first gradient liquid bile culture medium, culturing, measuring OD600, and if OD600gt is detected, determining that the single colony is not detected; and 0.6, the strain can be placed in a liquid bile culture medium of the next gradient, and the strain which can grow in the three gradients can be inoculated into fresh oxgall for culture. The method has the advantages that the escherichia coli strain with high beta-glucuronidase activity for efficiently cultivating calculus bovis can be obtained, in-vitro cultivation verifies that the escherichia coli strain has bile resistance, calculus bovis analogues can be obtained, and the physicochemical properties of the calculus bovis analogues are similar to those of natural calculus bovis.

The invention belongs to the technical field of traditional Chinese medicine authenticity identification and quality control, and particularly relates to an artificial intelligence calculus bovis trace element quality attribute rapid detection and discrimination method and device and electronic equipment. The method comprises the following steps: firstly, quickly and nondestructively acquiring calculus bovis comprehensive element fingerprint spectrum data by adopting a high-sensitivity X-ray fluorescence spectrum, and constructing a calculus bovis database; secondly, evaluating the quality consistency of the calculus bovis according to the similarity coefficient; and finally, establishing a back propagation neural network and a multi-layer sensor model, and realizing rapid and accurate discrimination of the natural product and the artificial product of the calculus bovis. Compared with a traditional method, the method has the advantages of rapidness, no damage, low cost and high accuracy, and is suitable for quality monitoring and market supervision of traditional Chinese medicinal materials.

The utility model relates to the technical field of bezoar forming induction, and discloses a bezoar forming induction device which comprises a first body and a second body, the outer side of the surface of the bottom end of the first body is fixedly sleeved with a first connecting mechanism, and the top of the second body is provided with a second connecting mechanism. Movable limiting mechanisms are movably clamped to the outer sides of the surfaces of the second connecting mechanism and the first connecting mechanism, each of the first connecting mechanism and the second connecting mechanism comprises an annular frame, and a fixing groove is formed in the side, close to the first body or the second body, of each annular frame; through mutual cooperation of the first connecting mechanism, the second connecting mechanism and the movable limiting mechanism, the first body and the second body can be stably connected, and otherwise, the first body and the second body can be quickly separated; the adsorption balls can be conveniently implanted into the inner sides of the first body and the second body, and the operation is convenient.

The invention relates to the field of traditional Chinese medicine, in particular to a traditional Chinese medicine composition for treating osteoarthritis and application of the traditional Chinese medicine composition in pharmacy. The traditional Chinese medicine composition is prepared from astragalus membranaceus, pseudo-ginseng, angelica sinensis, radix paeoniae rubra, white paeony root stir-fried with bran, stephania tetrandra, rhizoma alismatis, semen coicis, poria cocos, salvia miltiorrhiza, honeysuckle stem, rhizoma atractylodis, radix achyranthis bidentatae, dendrobe, polygala tenuifolia, processed pinellia ternate, thunberg fritillary bulb, calculus bovis factitius and liquorice according to a specific proportion, and has the effects of promoting blood circulation to remove blood stasis, clearing damp, reducing phlegm and activating meridians to stop pain. Experiments show that the traditional Chinese medicine composition can significantly improve the joint function of a patient with knee osteoarthritis and reduce the level of inflammatory factors.

This invention provides a compound traditional Chinese medicine composition, its preparation method, and its application in the preparation of drugs for treating allergic rhinitis, belonging to the field of traditional Chinese medicine technology. The compound traditional Chinese medicine composition of this invention includes: Antrodia camphorata, Paeonia suffruticosa, Cynanchum paniculatum, Cicadae periostracum, Calculus bovis, Borneol, and Mentha haplocalyx. Antrodia camphorata, the principal ingredient, fundamentally regulates immunity and reduces inflammation and swelling. Paeonia suffruticosa, Cynanchum paniculatum, and Cicadae periostracum assist in anti-allergy and clearing heat and wind. Calculus bovis and Borneol are adjuvant ingredients that resolve phlegm, open the orifices, clear heat, and relieve pain. Mentha haplocalyx guides the medicine upwards and relieves local symptoms. This invention treats allergic rhinitis using a combination of internal and external application. Internal administration exerts a systemic regulatory effect and enhances immunity, while external application to the nose quickly relieves symptoms. The comprehensive formula addresses both the root cause and symptoms, with the various drug components synergistically enhancing anti-inflammatory, anti-allergic, and immunomodulatory effects to achieve the therapeutic effect of treating allergic rhinitis.

The utility model relates to the technical field of calculus bovis cultivation, and discloses a bioreactor for in-vitro cultivation of calculus bovis, which comprises a reactor body, a material uniformizing mechanism arranged in an inner cavity of the reactor body, a plurality of groups of oxygen supply tanks arranged at the upper end of the reactor body, and a first electromagnetic valve arranged at the lower end of each group of oxygen supply tank, an oxygen supply mechanism is arranged at the bottom of the inner cavity of the reactor body and is arranged below the refining mechanism; through cooperation of the oxygen supply mechanism, the reactor body and the material uniformizing mechanism, oxygen can be uniformly introduced into the bottom of the inner cavity of the reactor body through the oxygen supply mechanism, so that the contact range between the oxygen and cells is expanded, and meanwhile, under the action of the material uniformizing mechanism, the oxygen can flow in the reactor body along with bile, so that the bile is uniformly dispersed. Therefore, the oxygen can be uniformly supplied to the cells, and the mixing uniformity of the bile and various raw materials for promoting cell differentiation is improved, so that the cultivation efficiency of the calculus bovis is improved.

The invention discloses a method for increasing the yield of bezoar through specific forage combination feeding. According to the method, through scientific treatment and directional feeding of the ox gall powder residues, appropriate physiological conditions are created for bezoar formation. Active ingredients in the treated residues are more easily absorbed by cattle, the gallbladder contraction rhythm is mildly adjusted, cholestasis is induced, and cholesterol is crystallized and separated out, which is the core mechanism of calculus bovis generation; meanwhile, due to the interval feeding rhythm, continuous stimulation is guaranteed, excessive burden cannot be caused to the hepatobiliary system of the cattle, the calculus bovis can be gradually formed in a stable physiological environment, the yield of the calculus bovis is increased from the source, and the double advantages of resource recycling and breeding health guarantee are achieved. Originally possibly discarded ox gall powder residues are converted into effective raw materials after being treated, the breeding cost is reduced, meanwhile, waste discharge is reduced, and the method is suitable for practical application of farmers.

The invention discloses a preparation method of a core-shell type hydrogel microsphere wrapping xanthogenic bacteria and production application of the core-shell type hydrogel microsphere in cultivation of calculus bovis in a cattle body. The preparation method specifically comprises the following steps: S1, preparing an external phase solution; S2, preparing a shell solution; S3, preparing a core solution; according to the application, the specially-made core-shell hydrogel microspheres are implanted through minimally invasive surgery, the microspheres can realize long-term efficient colonization of yellow bacteria so as to improve the bilirubin conversion efficiency, and also can specifically adsorb key enzymes and bilirubin particles, so that the yellowing period is remarkably shortened, and meanwhile, the high success rate and the high quality of calculus bovis are guaranteed.

The invention relates to the technical field of calculus bovis factitius detection equipment, and discloses an online detection device for producing calculus bovis factitius, which comprises an equipment rack, the hardness detection part, the picture acquisition part, the rolling powder preparation part, the rotary drum mechanism, the material loading mechanism and the stock bin driving tool are integrated on the equipment rack and are sequentially matched to realize online detection and pretreatment of the calculus bovis factitius, and the rotary drum mechanism is used as a core transmission part to drive the material loading mechanism to do uniform-speed circular motion, so that the material loading mechanism can perform uniform-speed circular motion according to a preset working procedure; the hardness detection part and the picture acquisition part are sequentially and precisely used for completing dual detection, then the rolling powder-making part is used for completing material pretreatment, manual intervention is not needed for material transfer in the whole process, tedious operation of traditional manual detection is thoroughly replaced, the labor intensity of operators is effectively reduced, and the working efficiency is improved. The defects that in the prior art, detection equipment and pretreatment equipment are mutually independent, connection is tedious, transfer time is long, and efficiency is low are overcome.

Disclosed are a traditional Chinese medicine composition for clearing heat, detoxifying, relieving sore throat, and reducing swelling, and a preparation method therefor, and use thereof. The traditional Chinese medicine composition is prepared from the following raw materials in parts by weight: 10-20 parts of Houttuyniae Herba, 8-15 parts of Astragali Radix, 8-15 parts of Andrographis Herba, 8-15 parts of Scrophulariae Radix, 8-15 parts of Platycodonis Radix, 8-15 parts of Archidendri Folium, 2-6 parts of Lonicerae Japonicae Flos, 2-6 parts of Bupleuri Radix, 2-6 parts of Belamcandae Rhizoma, 2-6 parts of Peucedani Radix, 1-4 parts of Trollii Flos, and 0.1-0.6 parts of Calculus Bovis Factitius. The effect of the traditional Chinese medicine composition in treating acute pharyngitis and fever abatement is superior to that of each comparative example.

The invention relates to a construction method and application of a bilirubin fingerprint spectrum for in-vitro cultivation of calculus bovis, and relates to the technical field of traditional Chinese medicine detection. The construction method can be used for fully and effectively separating and identifying bilirubin components in the in-vitro cultured calculus bovis and measuring the content of the bilirubin components in the in-vitro cultured calculus bovis. The construction method has important significance in the aspects of quality control, authenticity identification, pharmacodynamic substance fundamental research and the like of bilirubin.

The invention relates to the technical field of traditional Chinese medicines, in particular to a formula and a production process of an external ointment for treating herpes zoster. The traditional Chinese medicine is prepared from the following raw materials in parts by weight: rheum officinale, radices trichosanthis, pearl powder, coptis chinensis, golden cypress, cottonrose hibiscus leaves, herba lycopi leaves, bulbus fritillariae cirrhosae, radix paeoniae rubra, liquorice, frankincense, myrrh, calculus bovis, borneol, realgar, purslane, impatiens balsamina and vaseline. After the medicines are combined, a synergistic effect can be generated. The traditional Chinese medicine is applied to the affected part one to two times a day, can quickly eliminate heat, reduce swelling, relieve pain, cool and activate blood, diffuse and store heat, detoxify and recover dryness, and can be cured in 5-10 days. The traditional Chinese medicine is easy to obtain raw materials, simple in process, convenient to use, less in pain, safe and reliable, and has the effective rate of 100% and the cure rate of 95%. The external ointment for herpes zoster has good market prospect and development value, and is worthy of popularization.