11 results about "Syringin" patented technology

The invention discloses a preparation process of an ovateleaf holly bark total saponin bulk drug, and particularly relates to the field of traditional Chinese medicine extraction and purification, the preparation process comprises the following steps: S1, extraction: crushing an ovateleaf holly bark medicinal material, and carrying out reflux extraction by using an ethanol aqueous solution as a solvent to obtain an ovateleaf holly bark crude extract; and S2, purification: carrying out solid-liquid separation on the crude ovateleaf holly bark extract, and purifying the filtrate through a recrystallization process and a macroporous resin adsorption process in sequence to obtain the ovateleaf holly bark total saponin bulk drug. According to the invention, an effective component group of ovateleaf holly bark for treating ulcerative colitis is taken as a target, the effective component group comprises syringin, pedunculoside and ziyuglycoside II, and a complete extraction-purification integrated process is constructed; through an orthogonal test, a comprehensive weighted scoring method is combined, and extraction parameters are scientifically optimized, so that the transfer rate of the three functional components is maximized, the extraction efficiency is high, and the pertinence is extremely high.

The invention provides a method for evaluating the anti-fatigue effect of acanthopanax senticosus, which comprises the following steps of: establishing an evaluation system taking the content of syringin and the IC50 value of DPPH free radical scavenging rate as double-effect indexes, and determining a clear judgment critical value of the anti-fatigue effect of acanthopanax senticosus tea: when and only when a sample simultaneously meets the conditions that the IC50 value of DPPH is less than or equal to 35mu g / mL and the content of syringin is more than or equal to 5mg / g, judging the anti-fatigue effect of acanthopanax senticosus tea; the obvious anti-fatigue effect is judged. Experiments prove that the double-index system and the threshold value have significant correlation with the anti-fatigue effect, the prediction deviation is small, the judgment is clear, the result is visual, and a standardized scheme is provided for rapid and low-cost effect evaluation of the acanthopanax tea product.

This invention discloses a cultivation substrate for promoting the growth of Acanthopanax senticosus seedlings and its application, belonging to the field of plant cultivation technology. The cultivation substrate for promoting the growth of Acanthopanax senticosus seedlings provided by this invention uses perlite and peat as a framework to construct a loose, breathable, water-retaining, and fertilizer-retaining physical structure. By adding Bacillus proteolyticus bacterial solution, its growth-promoting, antagonistic, and organic matter-decomposing effects are utilized to improve the rhizosphere microecology. Combined with controlled-release fertilizer, precise nutrient supply is achieved. These three elements synergistically optimize the water, fertilizer, air, and heat environment and microbial community in the rhizosphere of Acanthopanax senticosus seedlings, promoting nutrient absorption and metabolism, effectively improving photosynthetic efficiency and antioxidant enzyme (SOD, POD) activity; and significantly promoting the accumulation of medicinal components. The yield of eleutheroside E in the roots can reach 13.93 times that of the control group, and the yield of syringin in the leaves can reach 2279.82 μg, providing an efficient solution for cultivating high-quality, robust seedlings.

The invention provides an acanthopanax fruit and leaf composite tea bag and a preparation method thereof, treated deastringency fruits and high-aroma fried leaves are compounded according to the precise ratio of the fruits to the fried leaves being 1: (0.75-1.2), and syringin in the fruits and syringin, flavone and other components in the leaves generate the best synergistic interaction effect through precise compounding of the fruits and the leaves. Meanwhile, aiming at high astringent taste of the fruits, a low-temperature wall breaking process of less than or equal to 40 DEG C is adopted, and directional astringent taste removal is performed on the premise of retaining activity; and for the leaves, segmented temperature-controlled stir-frying (de-enzyming at 180 DEG C + slow baking at 120 DEG C) is adopted, so that the contradiction between aroma enhancement and glycoside retention is balanced. By improving the processing technology and optimizing the fruit and leaf compounding ratio, the product has the characteristics of reservation of high-activity components, high antioxidant activity and the like, has remarkable and predictable effects, has a solid material basis for health-care functions such as fatigue resistance and the like, and has extremely high market competitiveness.

The application belongs to the technical field of traditional Chinese medicine detection, and specifically provides a construction method and a quality detection method for characteristic chromatograms of Sarcandra glabra medicinal preparation, wherein octadecylsilane bonded silica gel is used as a filler, acetonitrile is used as mobile phase A, and a water solution containing potassium dihydrogen phosphate is used as mobile phase B, a gradient elution program is continuously optimized, the column temperature is controlled to be 23-27 DEG C, 11 common characteristic peaks are finally obtained, 9 common characteristic peaks are effectively separated, the characteristic chromatogram obtained has a smooth baseline, the characteristic peaks have good peak shapes, and the detection time is short, thereby providing a scientific basis for comprehensively establishing the quality control standard of Sarcandra glabra formula granules. Moreover, the peak positions of tryptophan, syringin, isovanillin and magnoflorine can be accurately positioned, the known information of the characteristic peaks is increased, and the integrity and characteristics of Sarcandra glabra medicinal preparation (for example, formula granules and other preparations) are fully reflected.

The application belongs to the technical field of natural medicine chemistry, and particularly relates to a method for extracting compounds in Magnolia officinalis by using a low eutectic solvent and a detection method. Magnolia officinalis powder and a low eutectic solvent are mixed, and then soaking and ultrasonic extraction are sequentially performed to obtain an extraction liquid containing target compounds; the target compounds are magnoliabine, syringin, magnolol and honokiol. The low eutectic solvent is used to assist ultrasonic extraction of the Magnolia officinalis powder, and strong hydrogen bond interaction is formed between the low eutectic solvent and the target compounds, which is beneficial to the extraction of the target compounds, so that the extraction rate of the four target compounds in the Magnolia officinalis powder is improved.

The invention discloses a preparation method and application of an acanthopanax senticosus extract for cosmetics, and relates to the technical field of acanthopanax senticosus extract.The acanthopanax senticosus extract is prepared from water, an acanthopanax senticosus composition, a preservative, a stabilizer, a thickening agent, an aromatic, a coloring agent and an auxiliary medicine mixture, through the synergistic effect of the optimized step-by-step composite solvent preparation-soaking process and the ultrasonic-assisted extraction technology, the dissolution rate and extraction efficiency of target active ingredients such as syringin are remarkably improved, and the content of the active ingredients in the obtained extract is greatly increased; by adding a stabilizer, a preservative and the like in the preparation process and adopting a specific step-by-step mixing and air-drying standing process, active ingredients are effectively protected, degradation is reduced, data related to preparation of the acanthopanax senticosus extract and corresponding analysis results are managed, visualized and stored, preparation management of the acanthopanax senticosus extract can be realized through internet cloud management and control, and the method is suitable for popularization and application of the acanthopanax senticosus extract. And the intelligent level of preparation management of the acanthopanax senticosus extract is improved.

The invention provides a compound processing technology of acanthopanax fruit leaves and a compound tea bag, according to the processing technology, acanthopanax fruits are processed by adopting a low-temperature wall breaking technology at the temperature of less than or equal to 40 DEG C, tannic acid in the fruits is physically and directionally degraded, and directional astringency removal and glycoside protection are realized; meanwhile, a segmented process of combining instant fixation at 180 DEG C with slow baking at 120 DEG C is designed for frying the leaves, so that the problem that substances such as syringin and total flavonoids in the leaves are easy to degrade is accurately solved, and efficient retention of core functional components is ensured; meanwhile, the synergistic increase of active ingredients is realized by optimizing the fruit and leaf compounding ratio. The system integration technology is adopted, the two independent process lines are integrated and optimized through sequential control and waste heat recovery, the technical contradiction that fruits and leaves cannot be produced on the same line is solved, and energy consumption and cost are greatly reduced.

This invention provides an LC-MS / MS method for the simultaneous detection of multiple major components of Shengmai Yin (Codonopsis pilosula formula) in plasma. The analytes include syringin, schisandrol A, gomisin D, schisandrol B, gomisin G, schisandrin A, schisandrin A, schisandrin B, codonopsis glycoside I, codonopsis alkynyl glycoside, methyl ophiopogon flavanone A, and methyl ophiopogon flavanone B. The method includes the following steps: preparation of a series of standard curve working solutions; preparation of standard curve samples; preparation of quality control working solutions; preparation of quality control samples; preparation of a mixed internal standard working solution; pretreatment of the standard curve, quality control, and analyte plasma samples using protein precipitation; sample detection; and quantitative determination based on the peak area ratio of the analyte to the internal standard to obtain the standard curve. The methodological investigation results of this invention show that the established method meets the requirements for in vivo biological sample determination, the pretreatment process is simple, and the method has good sensitivity, strong specificity, and high specificity, making it suitable for the detection of compounds with low concentrations.

The invention provides a method for determining the content of multiple components in an Aidi preparation, and belongs to the technical field of medicines. The Aidi preparation is prepared from traditional Chinese medicinal materials including ginseng, cantharides, astragalus membranaceus and acanthopanax. The content determination method comprises the following steps: simultaneously determining cantharidin, ginsenoside Rg1, ginsenoside Re, ginsenoside Rb1, ginsenoside Rc, ginsenoside Rd, isofraxidin, syringin, formononetin, astragaloside, chlorogenic acid, eleutheroside E, calycosin-7-glucoside, astragaloside II, neochlorogenic acid, cryptochlorogenic acid and eleutheroside E1 in the Aidi preparation by adopting liquid chromatography-mass spectrometry; the composition is prepared from effective components such as ginsenoside F3, ginsenoside Rg2, azelaic acid and the like. Compared with the prior art, the method has the advantages that the contents of the 20 effective components in the Aidi preparation are simultaneously measured under the same chromatographic condition through liquid chromatography-mass spectrometry, the method is convenient and rapid, the requirement for product quality detection is greatly improved, the method is more suitable for quality control of drugs in the future, and the drug quality and the clinical drug effect are guaranteed.

The invention belongs to the technical field of under-forest planting, and particularly relates to an ecological cultivation method for intercropping cortex acanthopanacis under a Chinese fir forest, and the method comprises the steps: collecting under-forest long-term ecological factors and growth historical data, constructing an improved GWO optimized LSTM prediction model, predicting the ecological factors and cortex acanthopanacis growth indexes in the future 7 days, comparing the most suitable ecological factor range, and determining the growth index of cortex acanthopanacis. When the difference value exceeds the limit, the under-forest ecological environment is regulated and controlled in real time through cultivation measures such as optimizing the opening degree of the sunshade net through WOA. According to the cultivation method, the growth indexes such as the diameter at breast height and the height of the cedarwood and the root thickness, the root bark thickness and the syringin content of the cortex acanthopanacis can be remarkably improved, the yield of the cortex acanthopanacis is increased, meanwhile, the land resource utilization rate and the economic benefit per unit area are increased, and an effective technical mode can be provided for under-forest economic development.