16 results about "Saussurea" patented technology

The invention discloses a method for improving the biomass and flavone content of a saussurea involucrata cell culture, which comprises the following steps of: culturing yellow-white saussurea involucrata callus on a culture medium at the temperature of 24 DEG C, illuminating for 16 hours / day, subculturing once every 15 days and subculturing for three times to obtain yellow-white or yellow-green callus which grows vigorously and is compact in structure; the preparation method of the culture medium comprises the following steps: weighing MS, cane sugar, naphthylacetic acid, 6-benzyladenine, coconut extract and agar in a container, adding distilled water, fully stirring, fixing the volume to 1 L, uniformly stirring, and adjusting the pH value to obtain a basic culture solution; carrying out high-pressure sterilization on the basic culture solution, pouring a flat plate, and cooling to obtain a culture medium; wherein the coconut extract is one or two of coconut water or coconut milk. By adding coconut water or coconut milk, the biomass of the saussurea involucrata callus can be remarkably increased in cooperation with the MS culture medium, and compared with an existing report, the increasing multiple is 2-3 times that of the existing report.

The invention relates to the field of medicine, in particular to a sterilization composition and application thereof.The sterilization composition comprises water, chlorhexidine acetate and saussurea involucrata extract, and the mass ratio of chlorhexidine acetate to saussurea involucrata extract is 1: (10-40). The bactericidal composition has the following effects: (1) inhibiting the growth and reproduction of vaginal pathogenic bacteria; (2) relieving and anti-inflammatory effects are achieved; (3) a synergistic effect is achieved, the cost is low, and the bacteriostatic effect is good.

The invention discloses an externally-applied liniment containing saussurea involucrata and perilla oil for herpes zoster and a preparation method of the externally-applied liniment, and relates to the technical field of externally-applied traditional Chinese medicine preparations, the liniment is prepared from the following components in parts by weight: 30-40 parts of fresh stem and leaf extract of saussurea involucrata, 15-20 parts of perilla oil, 0.5-1 part of forsythin, 0.1-0.3 part of vitamin B12, 0.3-0.5 part of vitamin E and 40-50 parts of mountain spring water; according to the preparation method disclosed by the invention, the extract of the fresh stems and leaves of the herba ecliptae and the perilla oil are adopted as cores and compounded with the forsythin, the vitamin B12 and the vitamin E to form a synergistic effect system, and the optimized processes of ultrasonic extraction, reflux concentration, low-temperature squeezing, centrifugal purification and ultraviolet sterilization are combined, so that the active ingredients of all the components are fully released; the active ingredients of the saussurea involucrata and the forsythin synergistically inhibit virus replication and relieve inflammation, the perilla oil and the vitamin B12 jointly repair damaged nerves, the vitamin E protects skin barriers and improves the stability of the preparation, and the raw materials of the preparation are all natural ingredients or natural active factors, so that the safety is high, and the risk of skin irritation is avoided.

The invention belongs to the field of Tibetan medicines, and particularly relates to a Tibetan medicine composition for tonifying yang and a preparation method thereof. The Tibetan medicine composition for tonifying yang is prepared from the following raw materials in parts by weight: 120 to 130 parts of pomegranate, 30 to 40 parts of cortex cinnamomi, 15 to 25 parts of fructus amomi rotundus, 10 to 20 parts of fructus piperis longi, 45 to 55 parts of saffron crocus, 35 to 45 parts of chingma abutilon seed, 45 to 55 parts of radix asparagi, 70 to 80 parts of radix angelicae sinensis, 45 to 55 parts of mirabilis himalaica, 70 to 80 parts of fructus tribuli, 70 to 80 parts of snow lotus herb and 70 to 80 parts of five-root concentrated paste. The composition is scientific in formula, standard in preparation, high in safety and free of obvious side effects, sexual dysfunction and accompanying discomfort caused by kidney-yang deficiency can be improved in a targeted mode, and the clinical application effect is remarkable.

The application discloses a traditional Chinese medicine composition for dredging collaterals, resolving stagnation and relieving pain and a preparation method thereof. The composition is prepared from more than twenty kinds of traditional Chinese medicinal materials, such as ginseng, aconite, astragalus, asarum, salvia miltiorrhiza, dried tangerine or orange peel, pinellia, silkworm chrysalis, earthworm, earthworm, atractylodes, rhubarb, sparganium, antler, angelica, chuanxiong, persica, safflower, south saussurea, and camphor. The preparation method comprises the following steps: grouping the medicinal materials, respectively performing low-temperature drying, crushing, alcohol extraction and water extraction, combining the extracts, mixing the extracts with fine powder, drying, and forming. The application is based on the pathogenesis of deficiency, stagnation, coldness and phlegm and blood stasis, and realizes the effects of dredging collaterals, resolving stagnation and relieving pain through the compound compatibility of tonifying yang and benefiting qi and dispelling cold and dredging collaterals and a standardized process, and the drug efficacy is stable.

The invention provides a traditional Chinese medicine composition, an extract, a preparation and application thereof. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-25 parts of radix rehmanniae recen; 10-25 parts by weight of spina date seed; 6-18 parts by weight of coptis chinensis; 6-18 parts by weight of Scutellaria baicalensis; 10-25 parts by weight of adenophora tetraphylla; 10-25 parts by weight of red sage root; 10-25 parts by weight of Radix Ophiopogonis; and / or 6-18 parts by weight of Chinese herbaceous peony. The traditional Chinese medicine composition is an extract obtained after macroporous resin purification through water extraction or alcohol extraction and water precipitation, on the premise that effective components are guaranteed, the content of the effective components is increased, the dosage is reduced, the compliance of a patient is improved, and the classic effect is deduced through a modern technology. In animal or clinical experiments, the extract or the preparation provided by the invention has the advantages of high safety, less adverse reaction, obvious curative effect and very good clinical application value when being used for treating insomnia patients with fire excess from yin deficiency.

The invention relates to the technical field of feed additives, in particular to a traditional Chinese medicine composition for preventing and treating streptococcus iniae diseases of humpback perches as well as a preparation method and application of the traditional Chinese medicine composition. The traditional Chinese medicine composition comprises the following components in parts by weight: 10-15 parts of eucommia ulmoides, 10-15 parts of folium artemisiae argyi, 10 parts of radix angelicae, 10-13 parts of rhizoma zingiberis, 10-12 parts of liquorice, 7-9 parts of caulis spatholobi, 7-8 parts of herba ecliptae, 7-8 parts of radix ophiopogonis, 6-7 parts of poria cocos, 7-8 parts of hawthorn, 3-5 parts of radix aucklandiae, 3-4 parts of dendrobe, 3-5 parts of radix pulsatillae and 3-5 parts of radix puerariae. By feeding the traditional Chinese medicine composition provided by the invention, the weight gain rate of the humpback perches is increased by 20%, and the death rate of the humpback perches infected with streptococcus iniae is reduced by 10%.

The invention discloses a traditional Chinese medicine composition for treating bronchiectasis diseases. The traditional Chinese medicine composition is prepared from, by weight, 10-40 parts of cortex mori, 10-30 parts of wild buckwheat, 5-15 parts of radix scutellariae, 10-20 parts of fructus trichosanthis, 5-15 parts of semen armeniacae amarae, 5-15 parts of rhizoma pinellinae praeparata, 5-15 parts of cortex moutan, 10-20 parts of herba agrimoniae and 10-20 parts of radix adenophorae. The traditional Chinese medicine composition disclosed by the invention has the main effects of clearing lung and reducing phlegm, regulating qi and relieving cough, and reinforcing qi and nourishing yin to treat bronchiectasis caused by phlegm-heat obstructing lung and qi-yin impairment syndromes, especially bronchiectasis acute exacerbation, and has a good clinical application effect; the symptoms such as cough, expectoration and hemoptysis of patients in the acute exacerbation period of bronchiectasis are effectively improved, the life quality of the patients is remarkably improved, and the traditional Chinese medicine composition has great curative effect advantages and treatment potential.

The present application relates to a kind of methods for extracting active ingredients of Saussurea, including anisodine and umbelliferone, characterized in that, the extraction method includes the following steps: (1) obtain Saussurea paste; (2) 3-10% mass of ammonium bicarbonate is added in Saussurea paste, and the extract is obtained under the condition of ultrasonic power 200-400W, ultrasonic frequency 30-50kHz, room temperature for 30-50 minutes; (3) the extract is concentrated to relative density 1.1-1.3g / ml under reduced pressure to obtain extract infusion; (4) 0.8-1.5 times volume of cyclohexane is added in extract infusion for extraction, and the supernatant is concentrated under reduced pressure to obtain the final Saussurea extract. By using the method of the present application, the content of anisodine and umbelliferone in Saussurea extract can be effectively improved.

The invention discloses an anti-hypoxia composition containing saussurea involucrata culture and a preparation method thereof, belongs to the technical field of food, and relates to functional food. The anti-hypoxia composition containing the saussurea involucrata culture comprises the following components in parts by weight: 150-250 parts of the saussurea involucrata culture, 0-25 parts of a magnesium element reagent, 0-1.5 parts of a zinc element reagent and 0-4 parts of an iron element reagent, the isomaltitol tablet is prepared from the following raw materials in parts by weight: 400-500 parts of isomaltitol, 2-6 parts of hydroxypropyl methyl cellulose, 0.1-2 parts of sucralose, 0.1-2 parts of sodium carboxymethyl cellulose, 2-6 parts of magnesium stearate and 4-10 parts of food-grade coating powder. The composition disclosed by the invention not only can assist in improving altitude stress symptoms and relieving adverse effects of hypoxia on cardiopulmonary tissues, but also has the advantages of safety, portability, stability and compliance, and is suitable for various crowds exposed to a plateau environment.

The invention provides an external traditional Chinese medicine composition with a dysmenorrhea treatment effect, a preparation and a preparation method and application thereof, and relates to the technical field of traditional Chinese medicine compositions. The external traditional Chinese medicine composition is prepared from the following traditional Chinese medicine raw materials in parts by weight: 25 to 35 parts of radix aconiti preparata, 12 to 20 parts of fructus evodiae, 25 to 35 parts of radix linderae, 25 to 35 parts of rhizoma cyperi, 15 to 25 parts of radix aucklandiae, 25 to 35 parts of rhizoma corydalis, 15 to 25 parts of rhizoma chuanxiong, 15 to 25 parts of trogopterus dung, 15 to 25 parts of myrrh, 3 to 8 parts of cortex cinnamomi and 1 to 3 parts of camphor. According to the invention, the medicine effect directly reaches the local part through the specific matching of the medicines, the discomfort symptoms such as abdominal crymodynia and the like caused by dysmenorrhea of a patient can be quickly relieved, and clinical test results prove that the pain symptom of dysmenorrhea can be obviously improved by singly using the dysmenorrhea patch for one menstrual cycle, and the remission rate can be further improved and the pain duration can be further reduced by using the dysmenorrhea patch for two or more menstrual cycles; the pain relieving time is prolonged; and the use amount of the pain-relieving medicine is reduced.

A method of applying a topical skin composition to skin is disclosed. The method can include applying the composition to the skin. The composition can include Saussurea involucrate extract, Rhododendron anthopogon extract, and Oenothera biennis oil.

The invention relates to a herbal preparation that supports the treatment of gastric and duodenal ulcers and gastroesophageal reflux, along with a process for preparing this preparation, which involves a rational combination of natural herbal ingredients, optimal extraction techniques, and strict control of product content and quality. Specifically, the preparation is made from a mixture of herbs including White Peony (Radix Paeoniae lactiflorae), Ginger-processed Pinellia (Rhizoma Pinelliae praeparatum), Tangerine Peel (Pericarpium Citri reticulatae perenne), Chinese Yam (Tuber Dioscoreae persimilis), Saussurea lappae (Radix Saussureae lappae), and Gardenia Fruit (Fructus Gardeniae), with the ratio adjusted within an optimal range to maximize synergistic effects, combined with safe pharmaceutical additives to stabilize the dosage form and increase absorption.Preclinical trial results showed that the preparation significantly reduced the degree of gastric mucosal damage in an experimental ulcer model, while also reducing damage and improving esophageal morphology in a reflux model, with observed effects better than the untreated model and comparable to the control group Nexium 10 mg. These results demonstrate the preparation's ability to protect the mucosa, support damage recovery, and reduce inflammation. Furthermore, the optimized manufacturing process in terms of solvent, extraction conditions, and impurity removal resulted in a pure, stable herbal extract with good bioavailability, thus providing high therapeutic efficacy and safety.

The invention relates to the technical field of biomedical materials, in particular to neuroregulation composite gel constructed based on programmed assembly and a preparation method thereof.The preparation method comprises the following steps that an active unit is prepared, specifically, 3-5 parts of caulis spatholobi, 2-3 parts of pericarpium citri reticulatae, 2-3 parts of radix angelicae sinensis, 2 parts of radix bupleuri, 2 parts of radix aucklandiae, 1-1.5 parts of radix astragali, 1-1.5 parts of rhizoma atractylodis macrocephalae, 1 part of poria cocos and 1 part of rhizoma alismatis are selected and mixed; at least one of 1 part of radix salviae miltiorrhizae and 1 part of rhizoma chuanxiong can be added, and low-temperature composite enzymolysis is combined with a microwave-assisted extraction or ultrasonic-assisted extraction technology for extraction; various plant source active oligomers and synthetic peptide components are compounded, through the synergistic effect of the components, nerve regulation and anti-fibrosis activity are synchronously improved, abnormal neurotransmitter release can be effectively inhibited, nerve cell proliferation can be promoted, fibrosis-related gene expression can be remarkably inhibited, multifunctional integration is achieved, and the application prospect is wide. And the dual requirements of complex clinical scenes are met.

The invention provides a Changchun and longevity oral liquid and a preparation method thereof, and belongs to the field of traditional Chinese medicine preparations. Asparagus cochinchinensis, radix ophiopogonis, prepared rehmannia root, Chinese yam, radix achyranthis bidentatae, rehmannia root, folium cortex eucommiae, radix polygoni multiflori preparata, poria cocos, ginseng, radix aucklandiae, semen boitae, schisandra chinensis, rhizoma cibotii, pepper, rhizoma alismatis, rhizoma acori graminei, polygala tenuifolia, semen cuscutae, fructus rosae laevigatae, fructus lycii, raspberry and cortex lycii radicis are soaked in water and then decocted; filtering to obtain filtrate; concentrating the filtrate under reduced pressure to obtain fragrant paste; adding xylitol, adding potassium sorbate at the same time, adding purified water, and stirring to completely dissolve the xylitol and the potassium sorbate; and cooling the prepared liquid medicine to room temperature, standing, finely filtering by adopting a precision filtering device, filling the finely filtered liquid medicine into an oral liquid bottle under an aseptic condition, and carrying out circulating steam sterilization, cooling, bottle wiping, labeling and packaging on the sealed oral liquid to obtain the Changchun and longevity oral liquid. The medicine can be taken once a bottle is opened, the dosage is accurate, carrying and taking are greatly facilitated, and medication compliance is improved.

The application discloses a plateau herbal compound mosquito-repelling Tibetan incense and a preparation method thereof, which is composed of the following raw materials in parts by weight: artemisia capillaris 15-25 parts, Tibetan saussurea 8-12 parts, natural borneol 3-5 parts, benzoin 4-6 parts, rhododendron anthopogon 5-8 parts, tibetan wormwood 4-6 parts, impatiens walleriana 3-5 parts, meconopsis tangutica 3-5 parts, cnidium 3-5 parts, prunus buergeriana 2-4 parts, syzygium aromaticum 2-4 parts, zanthoxylum 4-6 parts, sandalwood 4-6 parts, sabina tibetica 10-15 parts, elm bark 5-8 parts, white willow 3-5 parts, brown sugar 2-3 parts, and agarwood 1-3 parts. The plateau herbal compound mosquito-repelling Tibetan incense is safe and non-toxic, has high and long-lasting mosquito-repelling efficiency, has the functions of soothing nerves and purifying air, has a green and mass-productive process, has ecological value, and is suitable for plain areas, high-mosquito-environment areas and sensitive people.