44 results about "Origanum" patented technology

The invention discloses a cattle feed additive. The cattle feed additive consists of the following raw materials in parts by weight: 4-16 parts of perilla frutescens, 2-20 parts of cyrtomium rhizomes, 10-30 parts of cod-liver oil, 2-10 parts of sodium selenite, 3-13 parts of Haixiao, 5-25 parts of radix polygalae, 2-12 parts of longan aril, 4-20 parts of Chinese yam rhizomes, 5-25 parts of vietnamese sophora roots, 3-17 parts of folium isatidis, 2-12 parts of endothelium corneum gigeriae galli, 4-16 parts of actinolitum brevifibrum, 2-12 parts of herba asari, 4-12 parts of origanum vulgare, 3-13 parts of Chinese pulsatilla roots, 4-16 parts of fleeceflower roots, 2-18 parts of radix achyranthis bidentatae, 1-9 parts of a bacillus natto agent, 2-10 parts of bacillus and 1-7 parts of active dry yeast. The cattle feed additive disclosed by the invention has the advantages of being rich in nutrition, capable of improving beef quality, increasing the survival rate of cattle and the like.

The invention relates to the field of food packaging, and provides a preparation method and application of an origanum vulgare essential oil-MOF modified alcohol-soluble protein preservative film. The preparation method comprises the following steps: mixing gamma-CD-MOF and origanum vulgare essential oil, reacting under a high-pressure reaction condition, centrifuging, washing and drying to obtain an origanum vulgare essential oil loaded MOF material; adding a plasticizer into the zein solution to prepare a membrane solution; and adding the MOF material loaded with the origanum vulgare essential oil into the film liquid, fully mixing, forming and drying to finally obtain the MOF-based food packaging film. According to the nano composite film disclosed by the invention, the water vapor barrier property, the ultraviolet barrier property and the oxidation resistance are remarkably improved. The nano composite film is applied to fresh-keeping experiments of strawberries and blueberries, so that the loss of nutritional ingredients is remarkably reduced, the shelf life of fruits is effectively prolonged, and an excellent fresh-keeping effect is shown. Compared with a traditional packaging material, the composite film provided by the invention not only is comprehensively optimized in performance, but also can provide more possibilities for a food fresh-keeping technology.

The utility model relates to the technical field of origanum vulgare essential oil antibacterial gel processing, in particular to origanum vulgare essential oil antibacterial gel filling equipment. According to the technical scheme, the filling device comprises a filling box body, a storage box and an outer plate, a workbench is welded to the lower surface of the filling box body, supporting legs are welded to the lower surface of the workbench, a fixing frame is fixed to the bottom end of the interior of the filling box body, a rotating roller is rotationally connected to the inner wall of the fixing frame, and the outer surface of the rotating roller is sleeved with a conveying belt; a connecting door is connected to the outer end face of one side of the filling box body through hinges, a handle is welded to the outer end face of one side of the connecting door, a storage box is fixed to the top end of the interior of the filling box body, an outer plate is welded to the lower surface of the storage box, an inner plate is movably inserted into the lower surface of the outer plate, and a supporting rod is fixed to the outer end face of one side of the inner plate. An outer rod is fixed to the outer end face of one side of the outer plate, and an inner rod is movably inserted into the lower surface of the outer rod. The discharging device can prevent gel from remaining on the outer surface of the discharging pipe.

The invention relates to the technical field of food packaging, and particularly discloses an antibacterial and antioxidant chitosan-based fruit fresh-keeping film and a preparation method thereof. The film comprises chitosan, glycyrrhizic acid, origanum essential oil, a plasticizer, a copper ion cross-linking agent, an acetic acid aqueous solution film-forming solvent, vesicle stable loading essential oil and a coordination cross-linking strengthening structure, and all the components construct a composite system through specific interaction. The preparation method comprises the following steps: firstly prefabricating glycyrrhizic acid-origanum vulgare essential oil vesicles, then adding vesicle powder and a plasticizer into a chitosan film-forming solution, uniformly mixing, casting and drying to form a primary film, and subsequently performing ionic crosslinking and balanced cutting to obtain a finished product. The film can be used for fresh-keeping packaging of fruits, has the advantages of being environmentally friendly, stable in structure and lasting in antibacterial and antioxidant activity, and can effectively delay reduction of the quality of the fruits; in addition, the preparation method disclosed by the invention is controllable in process, simple and convenient to operate, good in component synergism and beneficial to large-scale production and application.

The invention relates to the use of herbal preparation, characterized by presence of 4 dominant compounds (carvacrol a from about 35% to about 50%, γ-terpinene from about 10% to about 30%, thymol from about 10% to about 25%, p-cymene from about 8% to about 20%, as expressed in % of total peak area in GC / MS chromatogram), obtained by mixing at least two essential oils from species selected from the group of genera Satureja L., Origanum L. and Thymus L., to prepare food supplement or medicament for treatment and prevention of gastric Helicobacter pylori infection in humans. The mixture may be placed on liquid or solid carrier and capsulated in non gastro-resistant capsules. The invention also relates to dosage regiment of herbal preparation for treatment and prevention of patients with Helicobacter pylori infection which leads to successful eradication of bacteria without any side-effects.

The invention provides a traditional Chinese medicine feed additive for improving animal immunity and a preparation method thereof, and relates to the technical field of traditional Chinese medicine feed additives. The traditional Chinese medicine feed additive is prepared from twelve traditional Chinese medicines including astragalus membranaceus, immature bitter orange, fructus forsythiae, black beans, semen cuscutae, radix paeoniae alba, rosemary, thyme, litsea cubeba, mangosteen peel, cinnamon and origanum vulgare. The traditional Chinese medicine feed additive disclosed by the invention can be used for improving the immune organ index of an immunosuppressed mouse induced by cyclophosphamide, regulating the level of immune protein and inflammation-related factors and enhancing the phagocytic ability of macrophages of the mouse; the antibody titer of the Newcastle disease virus can be improved, the immune organ index of the chicken can be improved, and the secretion of IL-4, TNF-alpha and IFN-gamma in the chicken body can be promoted; mouse and broiler chicken tests show that the traditional Chinese medicine feed additive disclosed by the invention can improve the immune response capability of animals and enhance the immunity of the animals, and has a good application prospect in animal breeding.

The invention provides a preservative as well as a preparation method and application thereof, and belongs to the technical field of blueberry preservation. The preservative disclosed by the invention is prepared from 0.03 to 0.06 part of basil essential oil, 0.01 to 0.03 part of citronella essential oil, 0.05 to 0.09 part of purple perilla essential oil, 0.05 to 0.10 part of thymol, 0.01 to 0.05 part of sweet osmanthus essential oil, 0.01 to 0.05 part of origanum vulgare essential oil, 0.02 to 0.04 part of cinnamyl aldehyde, 0.05 to 0.08 part of cysteine and 0.5 to 2.0 parts of ethanol. The preservative disclosed by the invention is used for carrying out preservative and fresh-keeping on blueberries, and can be used for remarkably reducing the rotting rate of the blueberries, delaying the aging of the blueberries and keeping the color and flavor of the blueberries.

The invention provides a polypeptide modified phenol essential oil nano-liposome and a preparation method thereof, and the method comprises the following steps: (1) successively carrying out rotary evaporation, film hydration and ultrasonic dispersion on soybean lecithin, cholesterol and origanum vulgare essential oil to obtain an origanum vulgare essential oil nano-liposome suspension; and (2) sequentially mixing the origanum vulgare essential oil nano-liposome suspension and polylysine, and stirring to obtain the polypeptide modified phenolic essential oil nano-liposome. Soybean lecithin, cholesterol and origanum vulgare essential oil in a specific mass ratio and polylysine in a specific mass are self-assembled to form the nano-liposome in which antibacterial and antioxidant active substances are slowly released, growth and reproduction of escherichia coli and staphylococcus aureus can be effectively inhibited, meanwhile, main base materials of the nano-liposome are edible materials, and the nano-liposome has a good antibacterial and anti-oxidation effect. The product can be used for functional delivery of active substances and storage and preservation of fresh food, and meets the requirements of people for safe, nutritional and healthy diet and green and environment-friendly ideas.

The utility model discloses an oregano essential oil extraction device, and relates to the technical field of oregano essential oil, the oregano essential oil extraction device comprises an extraction box, the upper end of the extraction box is provided with a connecting port, the upper end of the connecting port is provided with a second connecting pipe, and the other side of the second connecting pipe is provided with a first connecting pipe; a spherical condenser is arranged at the lower end of the first connecting pipe, an oil-water separator is arranged at the lower end of the spherical condenser, a pretreatment device is arranged on one side of the upper end of the extraction box and comprises a cutting device and a rolling device, a stirring device is arranged in the extraction box, and a first supporting seat is arranged at the lower end of the extraction box; according to the scheme, the problems that the extraction process is slow and the extraction rate is low are solved.

The invention belongs to the technical field of fungus inhibitors, and particularly relates to a fungus inhibitor containing origanum vulgare essential oil and a fungus inhibition method. The origanum vulgare essential oil is prepared by mixing the following components: 100-150 parts of origanum vulgare essential oil and 30-50 parts of thyme herb essential oil, the origanum vulgare essential oil is prepared according to the following method: grinding origanum vulgare herb, adding an extraction solvent, performing ultrasonic extraction, then performing steam distillation, collecting distillate, and mixing the distillate with olive oil to obtain the origanum vulgare essential oil, the thyme herb essential oil is prepared according to the following method: crushing thyme herb, adding olive oil, sealing, illuminating, standing for 14-21 days, filtering, and collecting liquid, namely the thyme herb essential oil. The fungus inhibitor containing the oregano essential oil can inhibit aspergillus flavus, penicillium, aspergillus and claviceps purpurea at the same time.

The application discloses a functional high-collagen-peptide chicken egg feed additive and a preparation method thereof, relates to the technical field of laying hen feed, and raw materials of the feed additive and weight proportions of the raw materials are as follows: 1 part of arosa chinensis extract, 2 parts of origanum majorana raw powder, 1 part of artemisia leaf raw powder and 7-11 parts of collagen peptide; the feed additive formed by mixing the arosa chinensis extract, the origanum majorana raw powder, the artemisia leaf raw powder and the collagen peptide can effectively improve the Haff index of the chicken egg, the proportion of thick egg white, the viscosity and the eggshell quality in a short period of time and prolongs the egg product preservation period; the content of the collagen peptide in the chicken egg is effectively improved in a short period of time, the nutritional value of the chicken egg is improved, the method of supplementing the collagen peptide by eating the chicken egg plays a promoting role on human bone health, and the collagen peptide is supplemented by using egg white as a mask, so that the beauty function of repairing skin damage and preventing pigment deposition is realized.

The present utility model relates to method for producing a natural herbal bath soap utilizes a controlled oil-infusion and botanical integration process. The method comprises extracting a bio-active essence from oregano (Origanum vulgare) leaves into a carrier oil to form an infused oil, melting a soap base, and sequentially blending the oregano-infused oil with oatmeal and additives prior to solidifying the mixture in a mold. By employing controlled thermal infusion and sequential blending, this method prevents botanical degradation, uneven particle distribution, and skin irritation, yielding a stable, moisturizing bath soap free from synthetic additives.

The invention discloses application of a spice composition in a salted egg yellow argillization inhibition process, and belongs to the technical field of deep processing of egg products. The spice composition provided by the invention comprises a first composition and a second composition. Wherein the first composition comprises cinnamon, clove, pepper, anise and fennel; the second composition comprises lysimachia sikokiana, murraya paniculata, fennel, rhizoma kaempferiae and oregano. The mass ratio of the first composition to the second composition is 1: (0.5-1.5). According to the method, spices are creatively adopted as a modifier for preventing egg yolk from being muddy in the storage process of the salted eggs. Not only is the use of food additives such as traditional antioxidants and water-retaining agents avoided, but also the egg yolk muddy phenomenon caused by oxidation of protein lipid and over-high internal water activity in the storage process of the salted egg finished product is delayed.

The invention discloses a method for extracting hypoglycemic active components of origanum vulgare through combination of enzymolysis, ultrasonic treatment and salting-out. According to the method, origanum vulgare raw materials are used as substrates, cell walls are destroyed through enzymolysis pretreatment, and the release efficiency of active ingredients is improved; extracting hypoglycemic active substances such as luteolin and the like by utilizing ultrasonic strengthening; primary purification is realized by adopting a salting-out mode; the content of aglycone is increased through acidic hydrolysis, and then multi-stage separation and purification are carried out to obtain high-purity active ingredients; and finally, the stability of the extract is improved by using a beta-cyclodextrin inclusion technology. The method is short in technological process, high in efficiency, capable of obtaining the high-activity extract with the luteolin content larger than or equal to 30%, and suitable for research and development of functional food, health care products and drugs.

The invention discloses a traditional Chinese medicine composition for preventing and treating fish enteritis. The traditional Chinese medicine composition is prepared from 10-50 parts of rheum officinale, 10-30 parts of origanum vulgare, 10-30 parts of herba andrographitis, 10-30 parts of humifuse euphorbia herb, 5-20 parts of radix aucklandiae and 5-20 parts of rhizoma smilacis glabrae. The corresponding preparation method comprises the following steps: stir-frying the rheum officinale with yellow wine, and stir-frying half of the radix aucklandiae with bran; all the components are weighed according to the formula and smashed to obtain traditional Chinese medicine composition powder, or all the components are weighed according to the formula, extracted and concentrated to be prepared into traditional Chinese medicine composition oral liquid, granules, extract powder or tablets. The invention relates to application in preparation of medicine-containing feed or medicine for preventing and treating fish enteritis. The traditional Chinese medicine composition has a good prevention and treatment effect on bacterial enteritis of fishes, can improve the immune function and disease resistance of the fishes, relieve inflammatory response caused by pathogenic infection, delay the morbidity process of fish enteritis caused by pathogenic bacteria and reduce the death rate of the fishes, and also can improve the feed intake of the fishes, reduce the feed coefficient and effectively improve the production performance.

The invention discloses a super-hydrophobic antibacterial coating and a preparation method thereof, and belongs to the technical field of functional packaging materials and functional coating materials. The preparation method comprises the following steps: firstly, preparing oregano essential oil coated SiO2 microcapsules by combining an oil-in-water method and a sol-gel method; and then, constructing a coating through a layer-by-layer spraying method: forming a rough micro-nano structure by using origanum vulgare essential oil coated with SiO2 microcapsules, and jointly constructing the super-hydrophobic antibacterial coating by using polydimethylsiloxane as a low-surface-energy substance. The antibacterial rates of the coating on escherichia coli and staphylococcus aureus exceed 99%. The water contact angle of the constructed super-hydrophobic antibacterial coating ranges from 150 degrees to 160 degrees. The diameters of inhibition zones of the coating on staphylococcus aureus and escherichia coli are 10 mm and 5 mm respectively. Compared with uncoated raw paper, the coated paper has the same remarkable anti-adhesion effect on staphylococcus aureus and escherichia coli, and the anti-adhesion effect on the staphylococcus aureus and the anti-adhesion effect on the escherichia coli exceed 99% or above.

The application discloses a novel diterpenoid compound with anti-inflammatory activity separated from Origanum vulgare Linn. 20 H 18 O4, and a structural formula is as shown in formula I. A preparation method of the compound comprises the following steps: crushing dried medicinal materials of Origanum vulgare Linn., extracting by using ethanol, concentrating under reduced pressure to obtain total extract; after extraction by using petroleum ether, the target compound is obtained through silica gel column chromatography, Sephadex LH-20 gel column chromatography and preparation type high performance liquid phase chromatography separation and purification. In vitro anti-inflammatory experiments show that the compound can significantly inhibit NO generation in a LPS-induced RAW264.7 macrophage model, and the inhibition rate reaches 62.97%, and the compound shows good anti-inflammatory activity. The compound can be used for preparing medicines for preventing or treating inflammatory diseases such as enteritis, hepatitis and meningitis.

The invention discloses an acne-removing skin-care composition and a preparation method thereof.The preparation method comprises the steps that S1, hydrolyzed ginsenoside is prepared through an enzymolysis method, then first micro-emulsification is conducted, and micro-emulsified hydrolyzed ginsenoside is obtained; s2, extracting origanum vulgare essential oil by adopting a carbon dioxide supercritical extraction method, and then carrying out second micro-emulsification to obtain micro-emulsified origanum vulgare essential oil; s3, mixing the micro-emulsified hydrolyzed ginsenoside, the micro-emulsified origanum vulgare essential oil and the skin care base material, and on the basis of the total weight of the acne-removing skin care composition, the content of the hydrolyzed ginsenoside is 0.01-0.5 wt%, and the content of the origanum vulgare essential oil is 0.05-2 wt%. The method disclosed by the invention can be used for efficiently extracting and preparing the hydrolyzed ginsenoside and the origanum vulgare essential oil with high purity; the prepared plant component acne-removing skin-care composition has the effects of rapidly removing redness, resisting inflammation, inhibiting bacteria and removing acnes, is mild and non-irritant, and can meet the rapid acne-removing requirement of people with sensitive skin.

The invention discloses an antibacterial oxygen-resistant PVDC composite film and a preparation method thereof, and relates to the field of composite films, the antibacterial oxygen-resistant PVDC composite film comprises a PE film layer, an EVA hot melt adhesive film layer and a PVDC film layer from inside to outside; the PVDC thin film layer is obtained by coating a PVDC emulsion; the PVDC emulsion is prepared from vinylidene chloride, vinyl chloride, methyl acrylate, an emulsifier, an initiator, a pH buffer agent, deionized water, antibacterial microcapsules and a heat-conducting enhancer. PVDC has excellent oxygen barrier performance, and the requirement of the PVDC composite film on the oxygen barrier performance is met. The antibacterial microcapsule is obtained by coating origanum vulgare essential oil with cyclodextrin containing a polysiloxane chain and hindered phenol, and the heat conduction enhancer is obtained by introducing an epoxy group to the surface of a carbon nanotube. And the synthesized antibacterial microcapsules and the heat-conducting enhancer are added, so that the antibacterial property, heat resistance, oxidation resistance and mechanical properties of the PVDC composite film are improved.

The invention provides a preparation method of shellac-sodium caseinate composite nanoparticles loaded with origanum vulgare essential oil. The preparation method comprises the following steps: dissolving shellac in absolute ethyl alcohol by using an anti-solvent precipitation method, carrying out ultrasonic treatment to fully dissolve the shellac, centrifuging to remove insoluble substances, dropwise adding oregano essential oil, fully stirring, dropwise adding Tween 80 serving as a nonionic surfactant into sodium caseinate aqueous solutions with different concentrations, modifying the surface of the shellac with sodium caseinate by using a protein modification strategy, and drying to obtain the shellac-sodium caseinate composite material. Further, the shellac-sodium caseinate composite nanoparticles loaded with the origanum vulgare essential oil are obtained. Compared with single shellac nanoparticles loaded with the origanum vulgare essential oil, the shellac-sodium caseinate composite nanoparticles loaded with the origanum vulgare essential oil prepared by the preparation method disclosed by the invention are more uniform in particle size distribution, higher in packaging efficiency on the origanum vulgare essential oil, better in stability under an acidic environment condition and higher in oxidation resistance and antibacterial activity. The present technology provides a novel carrier material for encapsulating and delivering hydrophobic bioactive substances.

The medicine for nursing the biliary tract is prepared from the following raw materials in parts by mass: 5 to 10 parts of fructus mume, 3 to 7 parts of origanum vulgare, 4 to 8 parts of fructus citri sarcodactylis, 6 to 10 parts of radix curcumae and 4 to 9 parts of rhizoma cyperi. According to the traditional Chinese medicine composition, the smoked plums, the origanum vulgare, the fingered citron, the radix curcumae and the rhizoma cyperi are combined according to a specific mass part ratio, all the traditional Chinese medicine raw material components have a synergistic effect, the effects of effectively promoting biliary secretion and inhibiting gallstone formation are embodied, and the remarkable biliary tract nursing effect is achieved. The raw material components adopted by the medicine for nursing the biliary tract provided by the invention are non-toxic to a human body and do not generate obvious side effects, and the medicine is simple in preparation process, low in production cost and high in production efficiency.

The invention relates to a sea sludge component-containing composition with effects of nourishing color and repairing hair quality, and belongs to the technical field of daily chemicals, the composition mainly comprises the following raw materials: sea sludge, composite vegetable oil liposome, a peptide compound and hydrolyzed protein; the composite vegetable oil lipidosome comprises plum-leaf crab seed oil lipidosome, origanum vulgare leaf oil lipidosome and avocado fruit oil lipidosome. The plum-leaf crab seed oil, the origanum vulgare leaf oil and the avocado oil are respectively wrapped by lipidosome and then are compounded and combined for use, so that advanced oxidation failure can be avoided to a certain extent, slow release of active ingredients is realized, and a better hair color nourishing effect can be effectively realized through combination; the myristoyl pentapeptide-4, the sea sludge and the hydrolyzed yeast protein are compounded, so that the hair quality can be synergistically repaired from different dimensions, and the hair strength is further improved.

The invention relates to the technical field of plant sterilization and disinfection, in particular to a granular composition derived from plant sterilization and disinfection and a preparation process thereof. The particle composition is prepared from the following raw materials in parts by weight: 2 to 3 parts of chelating agent GL47, 8 to 10 parts of fatty acid, 5 to 6 parts of oleic acid, 12 to 15 parts of iso-tridecanol polyoxyethylene ether TO8, 10 to 12 parts of alkyl glycoside APG, 6 to 8 parts of disodium cocoyl glutamate, 1.5 to 2 parts of citric acid, 0.5 to 1 part of protease P300, 2 to 3 parts of seven-enzyme compound enzyme and 3.5 to 4.7 parts of modified hydroxypropyl methyl cellulose-plant extract. The origanum vulgare leaf extract, the garlic extract and the dandelion extract are adopted to form a plant sterilization and disinfection component, the sterilization effect is good, and the problem that the bioavailability is low due to the fact that the origanum vulgare leaf extract, the garlic extract and the dandelion extract serve as sterilization materials and are poor in water solubility is effectively solved.

The present invention relates to a composition comprising a propolis, an essential oil of Origanum vulgare, an essential oil of Thymus vulgaris, an alcohol and a penetrating agent, said composition being particularly useful for the preservation of tissues and organs, especially with regard to biological samples for analysis using a histological technique.

Disclosed herein is an advanced synergistic nano herbal composition having significant immunomodulatory and antiviral effects in human subjects, said formulation comprising the specific combination of HAVEs of Citrus limon, Cymbopogon citratus, Origanum vulgare, Thymus serpyllum, Tinospora cordifolia, Withania somnifera, Zea mays, Meyna laxiflora, Blumea lacera, Boswellia serrata, Cinnamomum verum, Mentha pipperata, Mentha arvensis, Nigella sativa, Cocos nucifera, Fagonia arabica, Azadirachta indica, Eucalyptus globulus, Citrus sinensis, Coriandrum sativum, Saccharum officinarum, Syzygium aromaticum, Dolichos biflorus. Resulting composition is sonicated to obtain the final advanced synergistic nano herbal composition having average particle size 133.2nm.

The invention discloses acetylated chitin nanocrystals and a preparation method of stable Pickering emulsion of the acetylated chitin nanocrystals, and belongs to the technical field of food colloid. According to the method, chitin is treated through an acidolysis and acetylation composite modification process, so that chitin nanocrystals with different acetylation substitution degrees are prepared. The obtained modified chitin nanocrystal has optimized surface properties and good particle size distribution, so that the modified chitin nanocrystal forms a stable physical barrier on an oil-water interface, and the stability and biocompatibility of an emulsion are remarkably improved. The Pickering emulsion prepared by using the modified nanocrystal solves the stability problem caused by hydrophobicity, high volatility and environmental sensitivity of origanum vulgare essential oil, and opens up a new path for application of natural biological materials in the field of Pickering emulsion.

The efficient distillation equipment comprises a distillation still main body, a liquid level sensor is fixedly installed on the surface of the distillation still main body, an electric heating plate is installed on the lower portion of the interior of the distillation still main body in an embedded mode, and a heat preservation box is fixedly connected to the surface of the distillation still main body. The upper surface of the heat preservation box is fixedly provided with a condensation structure, the surface of the condensation structure is fixedly connected with a collection tank, the distillation kettle main body comprises an upper cover, a connecting rod, a kettle body, a storage basket, a supporting ring, a screen, a handle, an embedding groove and an embedding column, the upper cover is hinged to the upper surface of the kettle body, the embedding groove is formed in the upper surface of the kettle body, and the storage basket is fixedly connected with the upper surface of the kettle body. The number of the embedded grooves is two, embedded columns are installed in the embedded grooves in an embedded mode, and handles are fixedly connected to the lower surfaces of the embedded columns. According to the efficient distillation equipment for extracting the origanum vulgare essential oil, disclosed by the utility model, origanum vulgare can be quickly placed and taken, and water can be automatically added into the kettle body.

The present invention relates to methods of applying a composition comprising thymoquinone in an amount effective to inactivate EHP spores and to reduce the rate of EHP infection wherein thymoquinone may be derived from Mentha America, Mentha pseudosciaena, or fennelflower foeniculata. The invention also relates to a method for controlling the proliferation of EHP in aquaculture, in particular the propagation of EHP infection in a population of shrimps. Another aspect of the invention relates to a method for controlling intracellular proliferation of EHP by directly inactivating EHP spores by administering to shrimps a composition containing thymoquinone, such as a composition containing nigella foeniculata seed oil. Another aspect of the invention relates to compositions containing only nigella foeniculata seed extract or in oil, in at least one embodiment, in combination with American mint oil, origanum oil, clove oil and cinnamyl aldehyde to control and inhibit the propagation of EHP infection and its related diseases.

The invention belongs to the technical field of cosmetics, and discloses a soothing composition, application thereof and a skin care product, the soothing composition is obtained by combining extracts of radix ophiopogonis roots, dandelion and origanum leaves; the extract is obtained by performing alcohol extraction on a plant combination of radix ophiopogonis roots, dandelions and oregano leaves, wherein the weight ratio of the radix ophiopogonis roots to the dandelions to the oregano leaves in the plant combination is (2-10): (2-10): (1-8). When the three extracts are combined, the inflammation reaction can be intervened from multiple angles, so that the inflammation is relieved, and the relieving purpose is achieved; more types of free radicals can be removed through mutual cooperation of the three components, and the overall free radical removing efficiency is enhanced through the synergistic effect. In addition, the moisturizing components of the three components can complement each other to construct a more perfect moisturizing system; the three components have strong synergistic effects in anti-inflammatory, anti-oxidation and moisturizing aspects, so that a better soothing effect is realized.

The invention discloses a novel diterpenoid compound which is separated from origanum vulgare and has anti-inflammatory activity, the molecular formula of the diterpenoid compound is C20H18O4, and the structural formula of the diterpenoid compound is shown as a formula I. The preparation method of the compound comprises the following steps: crushing a dried medicinal material of origanum vulgare, extracting with ethanol, and concentrating under reduced pressure to obtain a total extract; and after extracting with petroleum ether, separating and purifying through silica gel column chromatography, Sephadex LH-20 gel column chromatography and preparative high performance liquid chromatography to obtain a target compound. In-vitro anti-inflammatory experiments show that the compound can significantly inhibit NO generation in an LPS-induced RAW264.7 macrophage model, the inhibition rate reaches 62.97%, and good anti-inflammatory activity is shown. The compound can be used for preparing medicines for preventing or treating inflammatory diseases such as enteritis, hepatitis and meningitis.