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28 results about "Astragalus polysaccharide" patented technology

Astragalus Polysaccharides (APS) are active components of the polysaccharides extract of Astragulus, which has important antioxidant, anti-hypertensive, and immunomodulatory roles. Astragalus Polysaccharides (APS) attenuates TNF-α-induced insulin resistance by suppressing miR-721 and activating PPAR-γ and PI3K/Akt in 3T3-L1...

Fatty cream composition for maligant splanchnocoele hydrops and its preparing method

The present invention relates to a composition of aliphatic emulsion preparation for malignant thoracicoabdominal hydrops and its preparation method. It is made up by adopting pure natural anticancer medicine elemene and at least one polysaccharide selected from ginseng polysaccharide, astragalus polysaccharide, acanthopanax polysaccharide and lyceum polysaccharide as raw material. Said invention can obviously raise solubility of medicine, increase stability of medicine, effectively remove and kill cancer cells and raise immunity of body.
Owner:SINOPHARM A THINK PHARMA

A method for preparing an anti-tumor composition for pets

PendingCN122376657AYolkGreen Tea Polyphenols
This application belongs to the field of biomedicine, specifically relating to a method for preparing an antitumor composition for pets, aiming to solve the technical problems of low bioavailability, poor stability, and poor drug administration compliance of poorly soluble active ingredients in antitumor drugs for pets. The method includes: a raw material pretreatment step, in which curcumin, resveratrol, quercetin, green tea polyphenols, and astragalus polysaccharides are pulverized and sieved separately; an organic phase preparation step, in which egg yolk lecithin and solid lipids are dissolved in an ethanol-acetone mixed solvent, and curcumin and resveratrol are added and dissolved by stirring in a water bath; an aqueous phase preparation step, in which poloxamer F68 is dissolved in purified water and dissolved in a water bath; a high-pressure homogenization step, in which a nanoemulsion containing a solid lipid core is prepared; a moderately polar component encapsulation step, in which quercetin and green tea polyphenols are ultrasonically dispersed and then added dropwise to the nanoemulsion; a freeze-drying step, in which a nano-lyophilized powder is obtained; and an outer hydrophilic component coating step, in which astragalus polysaccharides are sprayed or adsorbed onto the surface of the freeze-dried powder. The composition obtained by this method is a core-shell multilayer nanoparticle with a core consisting of curcumin and resveratrol encapsulated by solid lipids, a middle shell adsorbing quercetin and green tea polyphenols, and an outer shell coated with astragalus polysaccharides. This application utilizes the above-mentioned layered encapsulation technology to achieve stable co-encapsulation of multiple antitumor active ingredients, improve the bioavailability of poorly soluble components, optimize drug stability, and enhance antitumor effects through multi-target synergistic effects. Simultaneously, it endows the composition with immunomodulatory functions and sustained-release properties. The composition can be formulated into a nano-lyophilized powder form, making it easy to add to pet food or formulate into a paste for administration, improving pet drug compliance. Figure 2 is a schematic diagram of the three-layer core-shell nanoparticle structure of the composition of this invention.

Traditional Chinese medicine body milk and preparation method thereof

The application discloses a traditional Chinese medicine body milk and a preparation method thereof. The traditional Chinese medicine body milk comprises the following components by weight: 5-15 parts of traditional Chinese medicine active ingredients derived from an ancient prescription of Danggui Yinzi, 1-3 parts of vitamin E, 0.5-2 parts of ceramide NP with a purity of greater than or equal to 95%, and 0.1-0.5 parts of natural borneol with a purity of greater than or equal to 99%, and the rest is an oil phase matrix, an aqueous phase matrix and an emulsifier. The traditional Chinese medicine active ingredients comprise angelica extract, astragalus polysaccharide, sophoramine and glycyrrhizic flavone, and are obtained by a low-temperature warm extract process at 40-45 DEG C. The preparation method comprises the following steps: raw material pretreatment, warm extract extraction, filtration and purification, precise compounding and fusion, emulsification and molding, and cooling and filling. The product has the advantages that skin irritation is less than 0.3, 24-hour moisturizing power is greater than or equal to 78%, the retention rate of herbal active ingredients is greater than or equal to 83.2%, and absorption is achieved within 5 minutes after smearing, and is specially used for improving the problems of dry skin, itching and difficult healing of wounds caused by blood deficiency and dryness caused by old age and chronic diseases.
Owner:NANCHANG MEDICAL COLLEGE

A polysaccharide compound stabilizer for improving the foam performance of low-alcohol wine and application thereof

PendingCN122445441AAstragalus polysaccharideWhite liquor
This invention relates to the field of alcoholic beverage processing technology, and discloses a polysaccharide compound stabilizer for improving the foam performance of low-alcohol baijiu (Chinese white liquor) and its application. The compound stabilizer comprises astragalus polysaccharide, tanshinone polysaccharide, and β-cyclodextrin. The mass ratio of astragalus polysaccharide to tanshinone polysaccharide is 1:3 to 3:1, and the two polysaccharides account for more than 70% of the solid mass of the compound stabilizer. β-cyclodextrin accounts for more than 0% and no more than 30% of the solid mass. The compound stabilizer is added to low-alcohol baijiu (Chinese white liquor) obtained by blending or reducing the alcohol content of light-aroma baijiu, with a final alcohol content of 5% vol to 15% vol, at an addition amount of 15 g / 100 mL to 20 g / 100 mL. After mixing, dispersion, static stabilization, and membrane filtration, low-alcohol baijiu with improved foam performance is obtained. This invention can increase the maximum foam height of low-alcohol baijiu and prolong the foam disappearance time, while maintaining the clarity, suitable viscosity, and sensory harmony of the liquor.
Owner:JING BRAND

Cchg / aps composite hydrogel, preparation method and application

PendingCN122272885AAstragalus polysaccharideWound healing
This application relates to a CCHG / APS composite hydrogel, its preparation method, and its application. A method for preparing the CCHG / APS composite hydrogel includes adding a chitosan solution dropwise to a carbomer solution, mixing, then adding an astragalus polysaccharide solution, adjusting the pH to 6.5-7.2, and performing cross-linking to obtain the CCHG / APS composite hydrogel. Firstly, performance characterization of the CCHG / APS hydrogel shows that it exhibits a unique loose and porous structure with good stability. Simultaneously, its rheological properties, swelling properties, and water retention capacity are all within suitable ranges, and it demonstrates excellent antibacterial properties, providing a favorable microenvironment for wound healing. In animal experiments, the CCHG / APS hydrogel exhibited a significant healing-promoting effect, and no obvious in vivo toxicity was observed throughout the experiment, confirming its good biocompatibility.
Owner:YANGZHOU UNIV

Application of Astragalus polysaccharides in promoting metabolism of lactic acid bacteria and improving quality and stability of fermented products

PendingCN122439739ABiotechnologySucrose
The application discloses an application of astragalus polysaccharide in promoting lactic acid bacteria metabolism and improving quality and stability of fermented products, and belongs to the technical field of fermented dairy product processing. The application adds 2 ‰ to 10 ‰ of astragalus polysaccharide and sucrose in skimmed milk with respect to the mass of the skimmed milk, inoculates lactic acid bacteria starter after pasteurization, and constant-temperature fermentation is carried out until the end point to prepare fermented products. The application utilizes the dual functions of astragalus polysaccharide in promoting lactic acid bacteria metabolism and strengthening milk protein gel network to realize the synergistic improvement of quality and stability of fermented products. Experiments show that when the addition amount of astragalus polysaccharide is 4 ‰, the sensory score of the fermented product reaches 87.3, and the water holding capacity is increased by 11.95 % compared with the control group; scanning electron microscopy shows that the gel network is dense and has few pores; when the addition amount is 6 ‰, the viable cell count reaches 1.23 x 10 8 CFU / ml; and when the addition amount is 8 ‰, the texture characteristics are optimal. The application is simple in operation, suitable for industrial production, and provides a new way for the development of functional fermented dairy products.
Owner:INNER MONGOLIA AGRICULTURAL UNIVERSITY

A food composition having antioxidant and procollagen synthesis promoting effects and a method for preparing the same

PendingCN122320230ABiotechnologyAntioxidant
This invention discloses a food composition with antioxidant and collagen synthesis-promoting effects and its preparation method, relating to the field of food technology. The food composition comprises the following ingredients in parts by weight: 300-500 mg collagen, 100-400 mg astragalus polysaccharide, 100-400 mg grape seed proanthocyanidins, 10-200 mg catechins, 5-100 mg ergothioneine, and 5-50 mg soybean oligopeptides. This food composition can increase the collagen content in the skin, enhance facial skin elasticity, reduce transepidermal water loss, and improve skin aging-related conditions. This invention constructs a dual-core synergistic formula of "antioxidant + collagen synthesis promotion" through the scientific formulation of seven active ingredients. All components of this invention use food-grade raw materials, making the formula mild and safe; all ingredients are natural extracts or edible raw materials, ensuring high safety, no obvious toxic side effects, and long-term daily use, making it suitable for a wide range of people.
Owner:SHANGHAI LANGSI ZHIYAO BIOTECHNOLOGY DEVELOPMENT CO LTD

Method for preparing high astragalus-containing dried apples by a circulation steaming and drying method

PendingCN122250631AFruits/vegetable preservation by coatingFruits/vegetable preservation by freezing/coolingBiotechnologyAstragalus polysaccharide
This invention discloses a method for preparing high-astragalus-content dried apples using a cyclic steaming and drying process, belonging to the field of food processing technology. Through a three-stage cyclic steaming and drying process involving three steaming cycles and three low-temperature drying cycles, combined with the steam explosion effect, pores are formed within the apple tissue. This allows the water-soluble component of astragalus, astragalus polysaccharide, and some fat-soluble component astragaloside A in astragalus to be continuously released under the action of warm steam. This promotes the rapid absorption of the water-soluble components of astragalus polysaccharide and some fat-soluble components of astragaloside A by the dried apples, which diffuse with the moisture, thus simultaneously increasing the content of astragalus polysaccharide and astragaloside A in the dried apples. Furthermore, by pre-soaking apple slices in a color-protecting solution and a preservative coating solution, and then combining this with the three-stage cyclic steaming and drying process, the polyphenol oxidase in the apples is deactivated by the hot steam, effectively preventing browning.
Owner:ANHUI BENCAO YITANG BIOTECHNOLOGY CO LTD

A composition for improving microcirculation in the pet's brain and nourishing nerves, its preparation method and application.

PendingCN122124118ANervous disorderKetone active ingredientsGinkgo Biloba Leaf ExtractVitamin B12
This invention discloses a composition for improving microcirculation in the pet's brain and nourishing nerves, its preparation method, and its application. Belonging to the field of pet medical technology, it specifically relates to a composition for improving microcirculation in the pet's brain and nourishing nerves, comprising: 2-5 parts of Ginkgo biloba extract, 10-20 parts of curcumin, 5-10 parts of α-lipoic acid, 75-125 parts of Astragalus polysaccharide, 0.5-5 parts of vitamin B12, and 0.25-2 parts of vitamin B1. This invention scientifically combines Ginkgo biloba extract, curcumin, α-lipoic acid, Astragalus polysaccharide, vitamin B1, and vitamin B12, utilizing the synergistic effects of each component in anti-inflammatory, antioxidant, microcirculation improvement, and neurotrophic effects, to provide a composition that can effectively improve microcirculation in the pet's brain and nourish nerves, filling a gap in the prior art.
Owner:ZHENGZHOU FUCHONG PET HOSPITAL CO LTD

Preparation method and application of piglet anti-stress and immunity enhancing preparation

The application belongs to the technical field of composite materials, and particularly discloses a preparation method and application of a stress-resistant and immunity-enhancing preparation for piglets, which is prepared by using sodium iron chlorophyll and sodium selenium-rich acid as core blood supplement elements, collocating an astragalus polysaccharide and a cordyceps polysaccharide compound polysaccharide system, combining functional oligosaccharides, antibacterial peptides and probiotics to construct an intestinal microecological regulation module, and supplementing with composite amino acids and vitamins to form a nutritional synergistic system, and is prepared through gradient sugar molecule inclusion, low-temperature microcapsule embedding and other innovative processes, so that the physical energy, qi and blood are supplemented simultaneously. The preparation can effectively reduce the incidence of hypoglycemia in newborn piglets, improve the disease resistance and immunity of the piglets, relieve weaning stress, improve the weaning survival rate and weaning weight, and simultaneously improve the nutritional supply of perinatal sows, reduce postpartum fatigue of the sows, improve milk quality and indirectly help the growth of the piglets.
Owner:HUNAN MODERN RESOURCES AGRI TECH CO LTD

A kind of hard capsule of anti-aging of five grain worm peptide and traditional Chinese medicine compound and its preparation method

PendingCN122321098ARHODIOLA ROSEA ROOTPharmaceutical medicine
This invention relates to the field of health food technology, and more particularly to an anti-aging hard capsule of *Polygonum multiflorum* peptide and traditional Chinese medicine compound, and its preparation method. By mass percentage, it comprises the following components: 40%–60% *Polygonum multiflorum* small molecule protein peptide freeze-dried powder, 10%–20% Astragalus polysaccharide extract, 5%–15% Polygonatum polysaccharide extract, 2%–8% Lycium barbarum polysaccharide extract, 1%–5% Panax notoginseng saponin extract, and 3%–10% auxiliary traditional Chinese medicine components and pharmaceutically acceptable excipients. The auxiliary traditional Chinese medicine components are Rhodiola rosea glycoside extract and Echinacea polyphenol extract or licorice powder. This invention's compound follows the principles of traditional Chinese medicine formulation, and the product is rich in small molecule peptides and various active ingredients. It can promote collagen synthesis, clear senescent cells, enhance immunity, resist oxidation, regulate intestinal flora, and improve microcirculation, exhibiting significant anti-aging and anti-fatigue effects. The preparation process is scientifically controllable and has wide applicability.
Owner:JINHUA HERUI LIFE HEALTH TECHNOLOGY CO LTD

Astragalus polysaccharide, preparation method and application thereof

This invention discloses Astragalus polysaccharide, extracted from Astragalus membranaceus. The average molecular weight of this Astragalus polysaccharide is 8-12 kDa, and its monosaccharides are mainly composed of galacturonic acid, glucose, galactose, and arabinose. This Astragalus polysaccharide is a GalA-type acidic polysaccharide that effectively reduces the deposition of immune complexes and the release of pro-inflammatory factors in renal tissue by regulating signaling pathways such as cGAS-STING. Simultaneously, it improves glomerular filtration function by stabilizing the podocyte cytoskeleton structure, exhibiting a synergistic protective therapeutic advantage. This invention also discloses a method for preparing this Astragalus polysaccharide.
Owner:GUANGDONG HOSPITAL OF TRADITIONAL CHINESE MEDICINE

Application of Astragalus polysaccharides in colon cancer drugs by regulating intestinal flora

PendingCN122320992ACD8Oncology
The application relates to application of Astragalus polysaccharide in colon cancer drugs by regulating intestinal flora, and extracts crude polysaccharide (ARCP) in Astragalus, which can be used for drugs for treating or preventing colon cancer, and the ARCP realizes the effect on colon cancer mainly by regulating intestinal flora; the ARCP can increase the proportion of CD8 + T cells, improve the tumor immune microenvironment, regulate T cell subgroups, the ARCP has the ability of up-regulating Tem subgroup, down-regulating Temra subgroup, making Tem the dominant subgroup, thereby increasing the cytotoxicity of CD8 + T cells, and improving the killing ability on tumor cells.
Owner:TIANJIN MEDICAL UNIV

Immunomodulatory compositions based on ovine liver proteolysate and methods of preparation

PendingCN122350336ABiotechnologyVitamin C
This invention discloses an immunomodulatory composition and its preparation method based on sheep liver protein hydrolysate, belonging to the field of health food. The composition, by weight, comprises 30-60 parts sheep liver protein hydrolysate, 10-25 parts wolfberry polysaccharide, and 10-20 parts astragalus polysaccharide, preferably containing 5-15 parts yeast β-glucan and 2-8 parts vitamin C. The proportion of oligopeptides <1000Da in the hydrolysate is not less than 85%. This invention employs a gentle deodorizing pretreatment with yeast and ginger extract, combined with a continuous, integrated process of two-stage enzymatic hydrolysis using endonucleases and exonucleases. This deodorizes while promoting protein conformational development, improving hydrolysis efficiency and achieving a balance between high oligopeptide yield and excellent sensory quality. Verification using the King's Law shows that the components exhibit significant synergistic effects, superior to single components in enhancing immunity, anti-oxidation, and auxiliary liver protection. It is highly safe and can be applied in health food and special medical food fields.
Owner:YAOYE BOSHENG (BEIJING) BIOTECHNOLOGY CO LTD

A feed additive for repairing intestinal injury of aquatic animals, a feed and a preparation method thereof

PendingCN122320135ABiotechnologyAquatic animal
This invention proposes a feed additive, feed, and preparation method for repairing intestinal damage in aquatic animals, relating to the field of aquatic feed technology. This invention aims to address the problem of intestinal damage in aquatic animals caused by various factors in aquaculture. The feed additive of this invention comprises, by weight, 1-3 parts selenium nanoparticles, 5-10 parts astragalus polysaccharide, and 3-5 parts γ-aminobutyric acid (GABA). The compound aquatic feed additive and its formulated feed provided by this invention, through the optimized combination and synergistic effect of selenium nanoparticles with astragalus polysaccharide and GABA, improve the repair capacity of intestinal damage in aquatic animals through multiple pathways and levels, effectively alleviating the adverse effects of decreased survival rate caused by environmental stress and significantly improving the production performance of aquatic animals. This invention solves the problems of low bioavailability and narrow toxicity threshold of traditional selenium preparations, achieving safe and efficient intestinal protection.
Owner:NORTHEAST AGRICULTURAL UNIVERSITY

A biological agent suitable for the growth of young pigeons, and a method for preparing and using the same

This invention discloses a biological agent suitable for squab growth, its preparation method, and its application, belonging to the field of feed technology. It comprises the following components by weight: 8-40 parts of microbial agent, 1-10 parts of additive, 1-10 parts of antioxidant, 0.5-5 parts of peptidoglycan, and 40-60 parts of montmorillonite. The microbial agent includes *Bifidobacterium animalis*, *Lactobacillus acidophilus*, *Lactobacillus paracasei*, and *Lactobacillus reuteri*. The additive includes at least one of yeast β-glucan and astragalus polysaccharide. The biological agent for squab growth of this application uses montmorillonite as a base material. Under the combined action of the microbial agent, additive, antioxidant, and peptidoglycan, it can regulate the intestinal health of breeding pigeons, improve their immunity, and increase immune factors in pigeon milk. This can improve the growth performance of squabs, reduce the culling rate of both breeding and squabs, thereby increasing economic benefits and showing broad application prospects.
Owner:GAN ZHOU BA WEI SHENG WU KE JI YOU XIAN GONG SI +1

A piglet feed additive and a preparation method thereof

The present application provides a kind of piglet feed additive and preparation method thereof, belong to feed additive technical field.The piglet feed additive includes: periplaneta americana drug residue enzymatic hydrolysate, xylo-oligosaccharide, lactoferrin, hawthorn extract, astragalus polysaccharide, corn starch and vitamin C;The preparation method includes: periplaneta americana drug residue enzymatic hydrolysate, hawthorn extract, astragalus polysaccharide, corn starch, vitamin C are added into mixing machine according to weight fraction, stirring speed is controlled, and powder mixture is obtained by mixing;The powder mixture is sieved, and the agglomerate that is not mixed uniformly is removed, to obtain the finished product of piglet feed additive.Piglet feed additive aims to overcome the defects of prior art, realizes drug residue resource utilization, and solves the problems such as diarrhea, growth retardation, low immunity and other problems caused by immature digestive system and weaning stress of weaned piglets.The preparation method is simple and controllable, the product is natural and residue-free, and provides an environmentally friendly, efficient and practical feed additive for the pig industry.
Owner:INTERFLAVOR (GUANGDONG) BIOTECHNOLOGY CO LTD

Preparation method and application of Astragalus extract for anti-liver aging

PendingCN122080250AOrganic active ingredientsDigestive systemBiotechnologyLIVER FATTY DEPOSIT
This invention provides a method for preparing Astragalus extract for anti-liver aging and its application, belonging to the field of natural product extraction and biomedicine technology. The invention uses a water extraction method to prepare Astragalus polysaccharide extract. The core steps are: pulverizing dried Astragalus, soaking in deionized water at a material-to-liquid ratio of 1:10 to 1:15 for 24 hours, extracting at 90℃ to 100℃ for 2 to 3 hours, filtering, concentrating to 1 / 4 of the original volume, and drying to obtain Astragalus polysaccharide powder. This invention also discloses the application of the Astragalus polysaccharide extract in the preparation of anti-liver aging products. The preparation process of this invention is simple, low-cost, and can be mass-produced. The obtained product has stable activity and controllable quality, and can significantly reduce fat deposition in aging livers, increase the activity of liver SOD and GSH-Px antioxidant enzymes, effectively delaying liver aging, and has good application prospects. The pure water extraction method for preparing the core active ingredient of Astragalus polysaccharide eliminates the need for large amounts of toxic organic solvents, making it environmentally friendly, with fewer operation steps and a simpler process, significantly reducing production costs.
Owner:DALIAN MEDICAL UNIVERSITY

A composition for enhancing disease resistance in frogs and its application

This invention discloses a composition for enhancing the disease resistance of frogs and its applications. The composition mainly consists of the core active peptide Peptide-3, astragalus polysaccharide, ginseng polysaccharide, prepared rehmannia root, and rosmarinic acid. Targeting "tiltosis and cataracts" in frogs caused by Elizabethanella miltiorrhiza, this invention works based on a synergistic mechanism of "targeted sterilization—immune warning—neural repair": Peptide-3 destroys the cell membrane of drug-resistant bacteria through a physical perforation mechanism to reduce pathogen load; plant polysaccharides induce non-specific immune warning in the body; prepared rehmannia root and rosmarinic acid synergistically scavenge free radicals, enhance SOD activity, and inhibit the expression of the pro-inflammatory factor TNF-α, precisely repairing damage to the central nervous system and eye tissues. Experiments show that the composition of this invention can increase the survival rate of diseased frogs to 92.4%, significantly reduce the incidence of tilted head and cataracts, and achieve a technological leap from single sterilization to comprehensive protection of the body.
Owner:HUNAN AGRI UNIV

A granule of a special medical food for anti-pleural tumor and a preparation method thereof

PendingCN122271516AGrape seedHouttuynia
This invention discloses a special medical food granule for treating pleural tumors and its preparation method. It is prepared from the following raw materials in parts by weight: 10-20 parts turmeric powder, 5-15 parts green tea extract, 5-15 parts grape seed extract, 10-20 parts Oldenlandia diffusa extract, 10-20 parts Scutellaria barbata extract, 5-15 parts Houttuynia cordata extract, 10-20 parts Astragalus polysaccharide, 5-15 parts Ganoderma lucidum spore powder, 5-10 parts β-glucan, 5-10 parts garlic powder, 2-5 parts quercetin, 20-30 parts Coix seed powder, 10-20 parts honey, and 2-5 parts freeze-dried royal jelly powder. The preparation process includes raw material pretreatment, extraction and concentration, premixing and encapsulation, total mixing, dry granulation, low-temperature boiling drying, granulation and sieving, quality testing, packaging, and storage. Based on modern molecular mechanism research, this invention constructs a four-dimensional synergistic system of "basic antioxidant, pleural targeting, immune remodeling, and microbiome editing" to achieve multi-level and multi-target intervention on the pleural tumor microenvironment.
Owner:YUNNAN HUANGJIA MEDICAL CIRCLE INST OF TRADITIONAL CHINESE MEDICINE

Astragalus polysaccharide feed fermentation device

The utility model discloses an astragalus polysaccharide feed fermentation device which comprises a fermentation box and a solution box, the solution box is fixedly mounted on the top surface of the fermentation box, a water pump is mounted on one side of the solution box, and the input end of the water pump is communicated and connected with the solution box through a liquid pumping pipe. The movable base, the spray head and the stirring rod are adopted, when the astragalus polysaccharide feed is fermented, the feed can be put into the fermentation box, then the first driving motor and the second driving motor are started, the second driving motor drives the stirring rod to rotate and stir the feed, the first driving motor drives the reciprocating lead screw to rotate, and the stirring rod rotates to stir the feed. According to the device, the movable base is driven to reciprocate, the stirring rod is driven to reciprocate, feed is comprehensively stirred, an astragalus polysaccharide solution in the solution box is pumped out by the water pump while the feed is stirred, the astragalus polysaccharide solution is sprayed into the feed through the spray head and mixed through stirring, the device plays a role in stirring and spraying at the same time, and the stirring uniformity and the fermentation efficiency are improved.
Owner:河南海创牧业有限公司

Veterinary vaccine enhancer and preparation and application thereof

This invention relates to the field of veterinary drug product technology, and more specifically, to a veterinary vaccine enhancer and its preparation and application. The veterinary vaccine enhancer comprises, by weight, the following components: 20-30 parts bacterial polysaccharide, 20-30 parts astragalus polysaccharide, 10-20 parts saponin, 4-12 parts vitamin B and C compound additive, and 1-5 parts polyethylene glycol 1000. The vaccine prepared using this invention is stable, safe, has high antibody titers, rapid antibody production, and long-lasting immunity, exhibiting excellent overall performance. The preparation method of the veterinary vaccine enhancer of this invention is simple, convenient, and low-cost, suitable for large-scale production and widespread application.
Owner:JINYUBAOLING BIO PHARMA CO LTD

A hierarchical taraxacum pollen and astragalus polysaccharide hydrogel integrated patch, and a preparation method and application thereof

PendingCN122097674ABandagesBiotechnologyAstragalus verus
The application discloses a kind of hierarchical dandelion pollen and astragalus polysaccharide hydrogel integrated patch and its preparation method and application, first to dandelion pollen is defatted and acidolysis treatment, obtain the porous pollen particle with drug loading capacity;Subsequently, porous pollen particles are immersed in rhodioside solution, and rhodioside is loaded onto porous pollen particles by physical adsorption, to obtain drug-loaded pollen;Prepared into raw and cooked paste mixed matrix with kudzu starch, then add prepared drug-loaded pollen and astragalus polysaccharide, after being mixed sufficiently, pre-gel solution is obtained;Finally, pre-gel solution is perfused into patch mold, and after heating and cooling solidification, demoulding is carried out, and the patch is obtained.The application realizes the antibacterial effect of astragalus polysaccharide by the rapid degradation of starch-astragalus polysaccharide matrix, and drug-loaded pollen microcarrier gradually releases rhodioside in wound microenvironment, to achieve long-acting active oxygen scavenging and anti-inflammatory effect.
Owner:NANJING DRUM TOWER HOSPITAL

A straw-medicinal plant composite substrate and its application

PendingCN122081193AComplex polysaccharide structurehigh activityFungiBacteriaNutritionGlycyrrhizin
This invention discloses a straw-medicinal plant composite substrate and its application. The straw-medicinal plant composite substrate includes straw, medicinal plants, water, a nitrogen source, and inorganic salts. The dry weight ratio of straw to medicinal plants is 3:1-7:1. The water content is 55%-65% of the total substrate volume, the nitrogen source is 0.1%-0.5% of the total substrate volume, and the inorganic salts are 0.05%-0.2% of the total substrate volume. In the two-way solid-state fermentation process, the straw is enzymatically hydrolyzed by fungi to provide basic nutrients, while the active ingredients in the medicinal plants (such as astragalus polysaccharides and glycyrrhizic acid) act as precursors or inducers, specifically regulating the secondary metabolic pathways of edible fungi, significantly increasing the yield of antimicrobial peptides, adenosine, and other antibacterial and immunomodulatory active substances. This achieves high-value utilization of agricultural waste, and the production process is pollution-free, meeting the requirements of sustainable development.
Owner:NANJING COLLEGE OF CHEM TECH

A composition for improving sensitive erythema and light damage and application thereof

PendingCN122351112ATert butylPharmacology
This invention belongs to the field of cosmetic technology, specifically relating to a composition for improving erythema and photodamage in sensitive skin and its application. The invention provides a composition for improving erythema and photodamage in sensitive skin, which is formulated from 4-tert-butylcyclohexanol, astragalus polysaccharide, ascorbic acid peptides, and supramolecularly refined mullein extract. Through multi-target and multi-pathway integration, it achieves a synergistic effect of "instant soothing, long-lasting moisturizing, barrier repair, and anti-photodamage."
Owner:N O D TOPIA (GUANGZHOU) BIOTECHNOLOGY CO LTD

Four-season traditional Chinese medicine tea and preparation method thereof

ActiveCN116440203BSterculia scaphigeraWolfiporia extensa
The present application relates to the technical field of medicinal and edible products, in particular to a four-season traditional Chinese medicine tea and a preparation method thereof. The raw materials of the four-season traditional Chinese medicine tea include chrysanthemum, Chinese wolfberry, white peony root extract, marsh marigold, longan aril, lily, embelia laevigata extract, poria cocos, ophiopogon japonicus, orange red, fat sea, acanthopanax extract, astragalus polysaccharide, dried ginger, cyperus rotundus extract, polygonatum, cornus officinalis, ginseng, jujube and licorice polysaccharide. The medicinal tea used in different seasons can play different effects, such as improving immunity, calming the heart and soothing the nerves, drying dampness and reducing phlegm, improving constipation, etc. When used in combination, the climate of four seasons and the changes of human body with four seasons can play a better role in regulating the functions of the body.
Owner:王梦雪

Electrolytic multi-vitamin feed for relieving calf weaning stress and application thereof

PendingCN122096308Akeep healthyEffectively maintain permeabilityOrganic active ingredientsAntinoxious agentsBiotechnologyWeaning
The present application relates to a kind of electrolytic multi-dimensional feed for relieving calf weaning stress and its application, by mass percentage, it includes the following components: vitamin 0.5%~5%, amino acid 0.05~1.5%, immunity promoter 0.1~2.5%, electrolyte 4~40%, additive 0.1~2.5% and carbohydrate 50~90%. Compared with prior art, the electrolytic multi-dimensional feed described in the present application, with milk source carbohydrate as main component, and add vitamin, electrolyte, glutamine and astragalus polysaccharide;Among them, lactose as milk source carbohydrate can simulate the carbohydrate in milk, help calf from liquid feeding to solid feed feeding, reduce the indigestion caused by the change of feed form;The synergy of each component can maintain the balance of body fluid, prevent electrolyte disorder caused by diarrhea or dehydration during weaning period;Promote the growth and repair of calf intestinal villi, maintain intestinal barrier function;Increase the immunity and antioxidant capacity of calf during weaning period.
Owner:SHANGHAI BRIGHT HOLSTAN CO LTD