106 results about "Intestinal immunity" patented technology

The invention discloses a feed additive for conditioning intestines of animals and belongs to the technical field of feeds. The additive comprises probiotic, oligosaccharide, plant polysaccharide and an adsorbent, wherein the probiotic is a composition of bacillus licheniformis or bacillus subtilis, butyric acid bacteria and lactic acid bacteria. According to the feed additive for conditioning the intestines of the animals, a plurality of components are compatible, so that the feed additive can play a role from different angles such as improvement on the intestinal micro ecology environments, repair of intestinal immune systems, anti-inflammation, anti-virus and adsorption of toxin; the sub-health status of the animals during breeding can be solved; especially, the feed-mixed diarrhea phenomenon of poultry can be improved; the disease resistance of the poultry is improved; the feed utilization rate is increased; the feed meat ratio is reduced; the production performance is improved.

The invention discloses an edible traditional Chinese medicine composition and a preparation method thereof. The edible traditional Chinese medicine composition is prepared from 6 to 30 parts by weight of white hyacinth bean, 6 to 30 parts by weight of dioscorea rhizome, 6 to 30 parts by weight of white poria, 6 to 30 parts by weight of coix seed, 6 to 30 parts by weight of semen nelumbinis, 6 to 30 parts by weight of gordon euryale seed, 3 to 15 parts by weight of dried ginger, 4 to 20 parts by weight of haw, 4 to 20 parts by weight of germinated barley, 3 to 15 parts by weight of inner membrane of chicken gizzard, and 3 to 15 parts by weight of orange peel. The edible traditional Chinese medicine composition has functions of invigorating spleen and tonifying qi, excreting dampness and stopping diarrhea, warming the middle warmer and promoting appetite, improving intestinal immunity, adjusting intestinal functions and promoting digestion. The edible traditional Chinese medicine composition is mainly used for treating children's diarrhoea caused by spleen deficiency, anorexia, dyspepsia and drug-induced diarrhea. The edible traditional Chinese medicine composition has mild properties and flavor, can be used as a medicine and a food, and has no toxic and side effects, a sweet smell, an excellent taste and a wide application range.

The present invention discloses a probiotic composition for enhancing immunity and an application of the probiotic composition. The probiotic composition comprises prebiotics, a K-MYL probiotic combination and functional substances, and the K-MYL probiotic combination comprises at least one of lactobacillus casei, lactobacillus bulgaricus, saccharomyces boulardii, lactobacillus reuteri and bifidobacterium animalis, or further comprises at least one of lactobacillus rhamnosus, lactobacillus acidophilus and bifidobacterium longum. The probiotic composition can significantly increase the number of intestinal effective microbial communities, improve intestinal immune functions, improve expressions of intestinal immune factors, resist virus infection and shorten recovery time after the virus infection. Moreover, probiotic strain combinations, the prebiotics, probiotic strains and the functional substances have remarkable synergistic enhancement effects.

The invention discloses a method for preparing a litchi polysaccharide fraction with gut immunoregulatory activity under activity tracing. According to the method, dried litchi pulp is subjected to ultrahigh-pressure enzymolysis assisted hot water extraction for extraction of litchi crude polysaccharide, deproteinization treatment, dialysis for micromolecule desorption and ethyl alcohol fractional precipitation in sequence to obtain the litchi polysaccharide fraction with gut immunoregulatory activity. The litchi polysaccharide prepared with the method has high solubleness and high gut immunoregulatory activity.

The invention discloses an amino acid additive capable of improving the growth capacity and intestinal health of a weaned pig. The effective constituents of the amino acid additive include threonine, leucine, arginine, isoleucine and glutamine. By adding 0.5-1.0% of amino acid additive to the basic ration of the piglet, the intestinal structure of the piglet can be improved, synthesis of intestinal mucous protein is promoted, the immunity of the intestinal tract is improved, in this way, the intestinal health of the piglet is improved, the diarrhea rate is the piglet is lowered, and the growth capacity of the piglet is improved.

In one aspect, a method for feeding animals includes selecting a plurality of strains of sporulated living microbes and form a microbial solution; and applying the microbial solution to a carrier. In another aspect during use, the method includes feeding animals with the microbial infused carrier to deliver microbes to a gastrointestinal tract alive; and germinating the microbes in the digestive tract and stimulating local intestinal immunity with the microbes.

The invention relates to the technical field of probiotics and particularly relates to lactobacillus reuteri and an application thereof. The invention provides Lactobacillus reuteri SLZX19-12 which ispreserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number of the Lactobacillus reuteri SLZX19-12 is CGMCC No. 20121. Lactobacillus reuteri SLZX19-12 can be planted in an animal body, and is high in acid resistance and cholate resistance; the good inhibition effect is achieved on escherichia coli and salmonella; feruloyl esterase can be generated, and release and digestion of fibers in the feed in digestive tracts are promoted; the lactobacillus reuteri SLZX19-12 is prepared into a microbial inoculum and then fed to animals, intestinal floracan be improved, intestinal immunity can be improved, intestinal health can be improved, and the effect is safe and reliable.

The invention relates to feed set meals for pigs in different physiological stages, and discloses a systematic nutrition scheme for sows to increase the number of market commercial pigs each year, and the benefits of pig farms are improved accordingly. The systematic nutrition scheme comprises a sow fecundity N+ series product, a piglet higher survival rate 7030 scheme, a pig growing and fattening more-profit making V+ series product and matched feeding patterns. According to the sow fecundity N+ series product, healthy reproduction of boars can be guaranteed by providing enough maintenance, growth, reproduction and immunization nutrition. According to the piglet higher survival rate 7030 scheme, the nutritional requirements of pig stocks in each production stage are met by taking a 'comprehensive nutrients + high and balance nutritional levels + high-quality nutrient sources ' scheme into account, the digestive absorption capacity and the intestinal immunity of the pig stocks are improved by guaranteeing the gastrointestinal tract health, and the self immunity of the pig stocks is reinforced by guaranteeing production nutrition and paying close attention to immune nutrition and stress nutrition. The pig growing and fattening more-profit making V+ series product is prepared according to different nutritional requirements of the pigs in different growth and development stages, and the obtained commercial pigs grow fast, low in feed ration and good in meat quality.

The invention discloses an intestinal immunity reinforcing agent used for pets, and a preparation method for the intestinal immunity reinforcing agent. The intestinal immunity reinforcing agent comprises the following ingredients in parts by weight: 10.0-20.0 parts of organic acids, 5.0 parts of compound plant extracts, 10.0-20.0 parts of yeast cell wall polysaccharides, 2.0-5.0 parts of yeast selenium and 50.0-80.0 parts of yeast hydrolysate. When the intestinal immunity reinforcing agent is added to pet food, the pet food capable of improving intestinal health and strengthening immunity canbe obtained. The pet food can be the conventional pet food or the pet food with an intestinal immunity reinforcing effect, and the adding amount of the intestinal immunity reinforcing agent can be 0.5-1%. The intestinal immunity reinforcing agent can be used for feeding pets, including dogs, cats and the like. The preparation method for the intestinal immunity reinforcing agent is simple and is easy to operate, the functions of nutrients are effectively guaranteed, stability is good, product free-running properties are good, the intestinal immunity reinforcing agent can be easily mixed and added with the pet food, and positive significance is performed for improving the immune functions of the pets.

The present invention discloses an immunity enhancing broiler feed preparation method, wherein raw materials such as 58-62 parts by weight of corn, 20-24 parts by weight of bean meal, 1-3 parts by weight of fish powder, 5-7 parts by weight of cottonseed meal, 4-6 parts by weight of cotton meal, 3-4 parts by weight of medicago powder, 1-2 parts by weight of calcium hydrogen phosphate, 1-2 parts by weight of stone powder, 0.3-0.5 part by weight of edible salt, 2-3 parts by weight of vegetable oil, 1-2 parts by weight of probiotics, and 4-5 parts by weight of a feeding attractant are subjected to crushing, fermentation, mixing, granulation and other steps to prepare the feed. The feed prepared through the method of the present invention, has the complete nutritional components, is added with the probiotic component with effects of intestinal balance benefiting and intestinal environment improving, and further has effects of effective broiler intestinal immunity increasing, nutrition digestion transformation capacity enhancing, broiler growth promoting, and intestinal disease occurrence probability reducing.

The invention relates to the technical field of pet food, in particular to cat food capable of improving intestinal immunity of a kitten. A formula of the cat food comprises main ingredients, additives, an intestinal protection ingredient and a natural antioxidant; the main ingredients comprise fresh chicken subjected to enzymolysis treatment, salmon, chicken oil, tapioca flour, sweet potato flour, potato flour, alfalfa pellets, beer yeast powder, kelp powder, chicken liver powder, salmon oil, carrot powder, pumpkin powder, tomato powder, apples, cranberries, milk calcium and yolk powder. The cat food is closer to a natural dietary structure of a cat and is balanced in nutrition, and meanwhile, saccharomyces cerevisiae boulardii can effectively prevent probiotics from being damaged by gastric juice and smoothly reaches intestinal tracts to play an effective role; lactoferrin powder enhances the intestinal resistance of the cat; inulin, the fructo-oligosaccharide and mannan oligosaccharide can increase the number of beneficial bacteria in the intestinal tracts of the cat and maintain flora balance; and psyllium husk powder can promote intestinal tract movement of the cat, promote excrement formation and reduce or relieve diarrhea symptoms of the cat.

The invention discloses health food with functions of moistening intestines and relaxing bowels. The health food comprises the following raw materials in percentage by weight: 1 to 10% of a folium sennae extract, 10 to 40% ofa semen cassiae extract,10 to 40% of an oat bran extract, 5 to 20% of citrus fiber, 5 to 10% of L-arabinose,5 to 25% of inulin and 5 to 10% of stachyose, and the sum of weight percentage of components is 100%. The invention further provides a preparation method of the health food. According to the invention, the components of the folium sennae extract, thesemen cassiae extract,the oat bran extract, the citrus fiber, L-arabinose,inulin, stachyose and the like are in effective compatibility together, therefore, the balance of anintestinal micro-ecological environment and intestinal florae can be adjusted to promote intestinal peristalsis, enhance intestinal immunity and perform comprehensive intestinal health; intestinal problems of constipation, diarrhea and the likeare fundamentally improved and prevented;furthermore, the health food is rich in nutritional components, good in taste and convenient to take, capable of avoidinginjuriescaused by strong excretion to a body after taken for a long term, and suitable for daily intestinal health nursing.

The invention discloses an enema for treating ulcerative colitis. Bulk drugs for the enema comprise, by weight, 10 to 20 parts of pasque flower, 10 to 20 parts of Chinese yam, 10 to 20 parts of common bletilla, 10 to 20 parts of root of large-flowered skullcap, 10 to 20 parts of dahurian angelica root, 10 to 20 parts of mutmeg, 10 to 20 parts of red sage root, 10 to 20 parts of glabrous greenbrier rhizome, 10 to 20 parts of garden burnet, 10 to 20 parts of milkvetch root, 10 to 20 parts of Chinese angelica, 10 to 20 parts of coptis, 10 to 20 parts of heydyotis, 10 to 20 parts of red halloysite, 10 to 20 parts of sophora flower, 10 to 20 parts of Chinese gall, 10 to 20 parts of garlic, 10 to 20 parts of pomegranate rind and 10 to 20 parts of atractylodes rhizome. The enema provided by the invention enables medicines to directly reach a focus, can be used for local flushing and can check diarrhea, diminish inflammation, resolve tetany, relieve pains, improve local blood circulation and metabolism, enhance immunity of intestinal tracts and promote healing of ulcers. With an anorectal therapy, the medicines can reach a focus after administration and medicines act on the focus in high concentration, which is beneficial for the medicines to take effect, and thus, the purposes of eliminating pathogenic factors and repairing injured tissue are achieved.

Disclosed is a method that efficiently screens immunobiotics that can effectively suppress an inflammatory immunologic effect induced in the intestines. The present disclosures relate to: the method for screening suppression agents that suppress an inflammatory immunologic effect in intestinal epithelial cells; a bacterial strain isolated by means of said screening method; and a composition containing said bacterial strain.

The present invention discloses an anti-enteritis grouper compound feed and a preparation method and a use method thereof. The compound feed includes the following components in percentages by weight: steam fish meal 13-18%, domestic fish meal 18-22%, fermented soybean meal 2-6%, sesame seed meal 17-20%, peanut kernel meal 3-7%, wheat flour 22-26%, blood meal 1-3%, earthworm powder 1-2%, soy lecithin 1-2%, sea fish oil 2-4%, calcium dihydrogen phosphate 1-3%, spirulina 0.5-1%, plantago depressa 0.2-0.5%, isatis tinctoria 0.2-0.5%, and premix 1-3%. The feed is finely prepared according to the growth characteristics and nutritional needs of groupers, has comprehensive nutrition and strong attractant, and can release growth potential of the groupers to the greatest extent. The Chinese herb medicines in the feed can improve the intestinal immune barrier and reinforce immune function.

The invention belongs to the technical field of feed and microorganisms, and in particular relates to antibiotic-free piglet breeding feed and a preparation method of the antibiotic-free piglet breeding feed. The antibiotic-free piglet breeding feed comprises the following components in parts by weight: 0.35 to 0.55 part of a compound enzyme preparation, 0.1 to 0.3 part of a microecological preparation, 0.7 to 0.9 part of nucleotide, 0.03 to 0.06 part of arginine, 1.0 to 1.5 parts of yeast, 0.8 to 1.2 parts of acidifying agents and 8 to 12 parts of piglet premix, wherein the compound enzyme preparation comprises cellulase, phytase and xylanase; and the microecological preparation comprises bacillus subtilis, lactic acid bacteria and lactobacillus casei. The antibiotic-free piglet breeding feed disclosed by the invention can obviously improve the microecological balance of piglet intestines, improve the intestinal immunity, lower the diarrhea rate of piglets and increase the survival rate, and has a good promoting effect on the later growth.

Formulations having a protein component, in which the protein contains one or more digestion-aiding proteins, and one or more immunoprotective proteins. The ratio by weight of the one or digestion-aiding proteins to the one or more immunoprotective proteins may be about 12:1 to about 1:1. The formulations may also contain a fat component, a carbohydrate component, and vitamins and minerals. These formulations can be used to provide nutritional support to a subject, either as dietary supplements or as a primary source of nutrition, such as for an infant formula. The formulations may also be used to promote or induce proliferation of intestinal cells, promote or induce differentiation of intestinal cells, prevent or inhibit growth of enteropathogenic Escherichia coli in the digestive system of a subject, prevent or inhibit bacterial growth in the intestinal lumen, increase interleukin-18 secretion by intestinal cells, or increase intestinal immunity.

The invention relates to the field of milk powder manufacturing, and in particular to novel milk powder and a manufacturing method thereof. The milk powder comprises the following components in partsby weight: OPO, whey protein powder (containing milk fat globule membranes and cephalin groups), raw milk, yak milk or whole yak milk powder, oligosaccharide, choline, DHA and lutein, and also comprises SN-2, wherein the content of the SN-2 is 60% or above of the weight of total palmitic acid in the milk powder. The OPO structural fat used in the novel milk powder is a new generation OPO, and thenovel milk powder has SN-2 close to the SN-2 level of breast milk, is beneficial to digestion and absorption of babies, and can improve energy intake, reduce constipation, enhance bone density, increase intestinal tract probiotics, reduce crying and improve night sleep. The novel milk powder can also improve cognitive ability, learning ability and memory of infants, can promote growth of probiotics, enhance the immune function of intestinal tracts, improve the stool character of the infants, reduce occurrence of constipation, and promote absorption and utilization of various nutrient substances.

The invention discloses a probiotic feed additive for improving the immunity of aquatic animals. The formation of the raw materials is as follows in parts by mass: 20-30 parts of probiotic fermented bacterium powder, 30-50 parts of oyster powder, 5-10 parts of cyclodextrin, 2-5 parts of vitamins, 1-2 parts of brown algae polysaccharide, and 0-10 parts of compound enzyme preparation. According to the present invention, aerobic and anaerobic mixed bacterium synergistic fermentation technology is adopted to co-ferment for preparing probiotic fermented feed additives, the immunity enhancement effect of the feed additive is significantly improved through the synergy between fermentation products and microorganisms, and the immunity effect has an important role in inhibiting the infection and growth of pathogenic microorganisms, restoring the balance of intestinal flora, and enhancing the intestinal immune function and physiological function. Experimental results show that the immunity of aquaculture animals such as Penaeus vannamei, can be significantly improved by the product, animal growth performance is improved, the feed coefficient is reduced, the breeding risk is reduced, and thebreeding economic benefit is increased.

The invention belongs to the technical field of biology, and provides lactobacillus reuteri and application thereof in a bee breeding process. The lactobacillus reuteri is preserved in the China General Microbiological Culture Collection Center on July 2, 2018, has a preservation number of CGMCC No.16043, and is classified and named as lactobacillus reuteri LP4. The lactobacillus reuteri is cultured in an MRS agar culture-medium, has round, milky white, neat-edged, smooth-faced, raised and non-transparent colonial form. The lactobacillus reuteri LP4 is spontaneously separated from intestines of Eastern worker bees which are bred by beekeepers in the Luoping County of Yunnan Province and freely digest rape flower honey in spring, has relatively good bacteriostatic activity, and is sensitiveto multiple antibiotics. The lactobacillus reuteri LP4 is added into syrup feeding bees in an amount of 108CFU / mL, so that the floral microecological structure in the intestines of bees can be improved, the intestinal immunity of bees can be enhanced, and the survival rate of bees can be improved.

The invention relates to high-concentration lactic acid bacteria freeze-dried powder capable of regulating blood glucose and blood lipid and a preparation method of the freeze-dried powder. The freeze-dried powder comprises the following main components: 1-100 parts of inactivated lactic acid bacteria freeze-dried powder, 1-100 parts of probiotic extracellular polysaccharide extract freeze-dried powder, 1-100 parts of probiotic lysate extract freeze-dried powder, 0-10 parts of ginseng extract, 0-100 parts of lentinus edodes extract, 0-10 parts of hericium erinaceus extract and 0-10 parts of tremella extract, wherein the content of the ginseng extract, the lentinus edodes extract, the hericium erinaceus extract and the tremella extract is not simultaneously 0. The high-concentration lacticacid bacteria freeze-dried powder disclosed by the invention has the effects of regulating the intestinal flora, improving the intestinal immunity, relieving chemical liver injury and improving the body immunity, and the liver is in charge of essence and blood, so that the effect of regulating blood glucose and blood lipid is achieved.

The invention discloses a swine immunopotentiator and its preparation method. The swine immunopotentiator belongs to the technical field of feed additives. The swine immunopotentiator provided by the invention comprises the following components: by weight, 12-20 parts of yeast beta-glucan, 10-20 parts of a poplar flower extract product, 15-20 parts of a bamboo shoot shell extract product, 15-25 parts of a bacillus subtilis bacterial powder for producing phytase, 6-10 parts of propolis, 2-5 parts of gamma-aminobutyric acid, 1-4 parts of mannan oligosaccharide, and 3-5 parts of chlorogenic acid. Through scientific compatibility and by enhancing specific and nonspecific immunity in the orgamism and regulating and controlling gut immunity and development, immune level of the organism is raised. Thus, swine health degree is raised, utilization rate of a feed is improved, and rapid growth of pigs is promoted. The swine immunopotentiator is a green safe high-efficiency swine immunopotentiator.

The invention provides a novel coronavirus intestinal infection model construction method based on a micro-fluidic organ chip, and particularly aims at simulating and constructing a series of intestinal tissue pathophysiological changes such as intestinal barrier integrity damage, mucus secretion abnormity and intestinal immune response activation occurring after novel coronavirus infection. The micro-fluidic chip is mainly composed of two layers of micro-channels, the channels are separated by a polydimethylsiloxane wedge-shaped porous membrane, each layer of channel is provided with an inlet and an outlet, and a static or dynamic environment can be formed through fluid. By respectively inoculating intestinal epithelial cells and endothelial cells into the upper channel and the lower channel on the chip and introducing circulating immune cells into the lower channel after virus infection, the miniature intestinal tissue on the chip is formed. Novel coronavirus particles are added into an upper channel of the chip, so that novel coronavirus exposure of intestinal tissues is simulated. The invention provides a multi-factor participated tissue level research system for the research of the SARS-CoV-2 infected intestinal pathogenesis.

The invention relates to an enzymolysis method of chicken intestinal canals, a carp feed containing intestinal canals and a feed preparation method, and belongs to the technical field of preparation of fish feeds. The invention aims at solving the problems of relatively high raw material prices and relatively low utilization rate of existing fish feeds. The enzymolysis method comprises the steps of: preprocessing the raw materials, mixing the intestinal canals, protease and water, and carrying out enzymolysis, wherein the protease is one of alkaline protease, papain, trypsin or neutral protease. The carp feed consists of the following raw materials in parts by mass: soybean meal, fish meal, enzymatically decomposed chicken intestinal canal protein, wheat middling, soybean oil, fish oil, phospholipid, choline chloride, calcium dihydrogen phosphate, sodium hydroxycellulose, a mineral element premix, multivitamins, methionine, threonine and lysine. A chicken intestinal canal protein feed,namely the carp feed contains trophic factors for promoting development of the intestinal tracts and is capable of improving activities of intestinal tract complements C3 and C4 and lysozyme, therebyimproving immunologic functions of the intestinal tracts.

The invention provides a oreochromisspp formula feed rapid to cause brittleness. The oreochromisspp formula feed is prepared from the following raw materials in parts by weight of 5-10 parts of beer yeast, 1-5 parts of fish meal, 1-5 parts of defatted tenebrio molitor powder, 70-80 parts of broad beans, 1-5 parts of fish oil, 1-5 parts of soybean oil, 0.2-1 part of monocalcium phosphate, 0.2-1 part of choline chloride, 0.2-0.6 part of vitamin C, 0.3-0.5 part of nano-selenium, 0.1-0.5 part of bile acid, 0.1-0.5 part of composite Chinese herbal medicines, 0.1-0.3 part of composite multiple vitamins and 0.1-0.5 part of allicin. Breeding test results show that the compound feed can meet all nutritional requirements of oreochromisspp in the growth process. On the basis of conventional oreochromisspp brittleness feed components, the addition quantity of broad beans is greatly increased, and the breeding period of the oreochromisspp having crisp meat is effectively shortened. The defatted powder, the beer yeast powder, the nano-selenium, the bile acid, the allicin and the composite Chinese herbal medicines are added. The raw materials and additives are comprehensively applied, so that theimmunocompetence of livers and intestinal tracts of oreochromisspp can be effectively improved, the disease resistance of oreochromisspp is improved, and the death rate and loss are reduced.

In one aspect, a method for feeding animals includes selecting a plurality of strains of sporulated living microbes and form a microbial solution; and applying the microbial solution to a carrier. In another aspect during use, the method includes feeding animals with the microbial infused carrier to deliver microbes to a gastrointestinal tract alive; and germinating the microbes in the digestive tract and stimulating local intestinal immunity with the microbes.

The invention provides preparation and application of premixed feed for a raccoon dog in a growing period, belongs to the technical field of feed, and particularly relates to premixed feed and a preparation method for increasing feed utilization rate and the growth speed and immunity of the raccoon dog in the growing period. According to the premixed feed, the digestive rate of the raccoon dog in the growing period for nutrient substances in the feed is increased, the intestinal environment of the raccoon dog in the growing period can be improved, intestinal immunity is improved, the feed utilization rate is increased, reduction of the growth performance due to diarrhea of the raccoon dog in the growing period can be prevented, the growth speed and immunity of the raccoon dog in the growing period can be effectively improved, intestinal diseases such as the diarrhea of the raccoon dog in the growing period is reduced, the anti-virus capability and immunity of animals are enhanced, the economic benefit of artificial raccoon dog breeding is improved, and drug residues and heavy metal content in a carcass are reduced.

The invention relates to the technical field of microorganisms, in particular to bifidobacterium bifidum capable of reducing fat, relieving hyperglycemia and regulating intestinal immunity and application of the bifidobacterium bifidum. The preservation number of the bifidobacterium bifidum B11 is CGMCC (China General Microbiological Culture Collection Center) No.24381. The strain has good tolerance to gastric acid environment and bile salt and can effectively improve glucose and lipid metabolism disorder phenomena induced by obesity and the like, and viable thalli, inactivated thalli or metabolites of the bifidobacterium bifidum B11 have the capacity of improving constipation or repairing intestinal mucosal barriers, so that the bifidobacterium bifidum B11 can be used for preparing the oral preparation for treating constipation. Meanwhile, the organism immunity can be remarkably improved by viable thalli or inactivated thalli.

The invention provides a composite prebiotics comprising inulin, galactooligosaccharides, xylitol and yeastbeta-glucan, and the composite prebiotics comprises a function for adjusting the human body intestinal flora. According to the composite prebiotics, several natural prebiotics are selected to produce effects collaboratively, and a component capable of enhancing the intestinal immunity is added so that the intestinal health is improved in a comprehensive manner. The composite prebiotics mainly comprises natural components, the taste is tried to keep the inherent original ecological taste,and customers can conveniently and randomly perform matching according to preferences. It is verified that through in-vitro experinents that the composite prebiotics makes inulin, galactooligosaccharides, xylitol and yeastbeta-glucan compatible with each other so that better functions are realized, and adverse reactions including exhaust and flatulence caused by inulin are improved as much as possible.