55results about How to "Relieve inflammation" patented technology

The invention discloses a liver-targeting drug liposome and application thereof, and relates to the field of drug delivery, cholate and mannose are used for respectively modifying phospholipid molecules DSPE-PEG2000, two raw materials DSPE-PEG2000-CA and DSPE-PEG2000-MAN composed of the liposome are synthesized, and then the liposome is prepared into the liver-targeting drug liposome. The liposome with liver targeting property is obtained from the liposome, cholesterol, DSPC, DC-cholesterol and a water-soluble therapeutic drug according to a certain proportion, the liposome has relatively high cell safety and liver targeting property, and the therapeutic effect of the corresponding drug can be remarkably improved after the drug is embedded.

The invention provides an anti-hair loss and anti-dandruff composition and a preparation method thereof, and belongs to the technical field of wash supplies. The anti-hair loss and anti-dandruff composition is prepared from the following raw materials: a plant raw material, a plant extract, a caffeine composition and an oil control composition, wherein the plant raw materials comprise the following raw materials in parts by mass: 5-20 parts of ginger root, 5-20 parts of black ginger root, 5-20 parts of alpinia japonica root, 1-3 parts of ligusticum wallichii, 5-10 parts of radix sophorae flavescentis, 2-4 parts of fructus cnidii, 1-5 parts of fructus viticis, 3-5 parts of saponin, 5-8 parts of soapberry peel, 1-5 parts of dandelion, 5-8 parts of polygonum multiflorum, 1-3 parts of mulberry, 3-6 parts of cacumen biotae, 3-6 parts of mulberry leaf, 7-10 parts of purslane and 1-4 parts of mangnolia officinalis; the plant extract is prepared from the following raw materials in parts by mass: 5 to 20 parts of aloe extract, 1 to 10 parts of herba menthae extract, 5 to 20 parts of fructus forsythiae fruit extract, 5 to 20 parts of tea leaf extract, 5 to 20 parts of herba centellae extract and 1 to 10 parts of cordyceps militaris extract. The composition prepared by the invention not only has good anti-dropping and anti-dandruff effects, but also has good stability.

The invention discloses a preparation method of compound polysaccharide microspheres capable of releasing NO. The preparation method comprises the following steps: cross-linking swallow polysaccharide with L-ARG, and preparing L-ARG-containing swallow polysaccharide hydrogel through a Mannich reaction; then loading EGCG (epigallocatechin gallate) onto the L-ARG-containing swallow polysaccharide hydrogel through a Schiff base reaction, and obtaining the compound polysaccharide microspheres capable of releasing NO by utilizing an emulsification method. The invention also discloses an application thereof. The hydrogel microsphere capable of targeting the colon is prepared, and the hydrogel microsphere can be accurately exploded at the colon part after being swallowed. A dextran sodium sulfate (DSS)-induced IBD mouse model is established to test the drug effect, and the result shows that the compound polysaccharide microspheres have a remarkable treatment effect on DSS-induced ulcerative colitis, can obviously improve the symptoms of ulcerative colitis, and provides a theoretical basis and a clinical basis for new drugs for clinically preventing and treating ulcerative colitis.

The invention relates to combined lactobacillus salivarius LS100 for inhibiting vaginitis pathogenic bacteria and preventing and treating vaginitis and application of the combined lactobacillus salivarius LS100. The combined lactobacillus salivarius LS100 is preserved in the China General Microbiological Culture Collection Center (CGMCC), and the preservation number is CGMCC NO.32135. The combined lactobacillus salivarius LS100 has good hydrogen peroxide production capacity and adhesion capacity, and can be used for preparing medicines for preventing and treating vaginitis. The traditional Chinese medicine composition has a relatively strong inhibition effect on main vaginitis pathogenic bacteria, is effective on nutritional pathogenic bacteria, and can also reduce form transformation and biological membrane formation of the pathogenic bacteria and prevent generation of drug resistance; besides, the fermentation product can reduce the content of pathogenic bacteria metabolites, regulate the secretion of cell factors and play a role in relieving inflammation, so that the fermentation product can be used for preparing products for preventing and treating genital tract pathogenic bacteria infection and / or preventing and treating vaginitis.

The invention discloses a fermented caffeine eye cream composition. Comprising the following components in parts by weight: 30 to 80 parts of a fermentation composition, 1 to 5 parts of caffeine, 0.1 to 0.3 part of hydroxypropyl tetrahydropyrantriol, 0.5 to 2 parts of nicotinamide, 0.1 to 1 part of squalane, 0.01 to 0.5 part of a ceramide composition, 0.005 to 0.05 part of dipeptide diaminobutyryl benzyl amide diacetate, 0.005 to 0.05 part of a polypeptide composition, 0.01 to 0.5 part of carnosine, 0.01 to 0.5 part of tetrahydromethylpyrimidine carboxylic acid and 3 to 12 parts of a plant extract. The invention also discloses an eye cream containing the eye cream composition. The fermented caffeine eye cream composition provided by the invention can effectively smooth the skin surface, and is beneficial to preventing and comforting aging, improving skin elasticity, improving dark circles, relieving edema and removing under-eye puffiness.

The invention discloses a probiotic / mucoprotein loaded oral microsphere system as well as a preparation method and application thereof, and belongs to the field of compositions. The preparation method of the system comprises the following steps: dissolving probiotics, Mucin and HAMA in double distilled water containing phenyl lithium phosphate LAP and calcium chloride to prepare a gel matrix solution; adding the dissolved gel matrix liquid into an oil phase solvent, and stirring at a high speed in a container; after uniformly stirring, carrying out an ultraviolet light crosslinking reaction, and after the reaction is finished, fully cleaning the obtained microspheres to remove the redundant oil phase solution, so as to obtain microspheres; and dispersing the obtained microspheres in a sodium alginate solution under an acidic condition, uniformly mixing, carrying out a cross-linking reaction, and filtering and cleaning after the reaction is finished, so as to obtain the probiotic / mucoprotein loaded oral microspheres. According to the invention, HAMA and SA are utilized to prepare an oral microsphere system resistant to gastric acid to co-deliver Mucin and EcN, so as to realize continuous and effective regulation and control of unbalanced intestinal flora by probiotics.

The invention relates to combined lactobacillus salivarius LS360 for preventing and / or improving female genital tract infection and application of the combined lactobacillus salivarius LS360. The combined lactobacillus salivarius LS360 is preserved in the China General Microbiological Culture Collection Center (CGMCC), the preservation number is CGMCC NO.32134, and the combined lactobacillus salivarius LS360 has good biological characteristics and endurance capacity and can be used for preventing and / or improving female genital tract infection. The traditional Chinese medicine composition has a relatively strong inhibition effect on main vaginitis pathogenic bacteria, is effective on nutritional pathogenic bacteria, and can also reduce form transformation and biological membrane formation of the nutritional pathogenic bacteria and prevent and treat drug resistance; besides, the bacterial strain and the fermentation product can also reduce the content of pathogenic bacteria metabolites, regulate the secretion of cell factors and play a role in relieving inflammation, so that the bacterial strain and the fermentation product can be used for preparing products for preventing and treating female genital tract pathogenic bacteria infection, preventing and treating vaginitis and / or removing pudendum peculiar smell.

The invention discloses a method for entrapping a silymarin and escin composition by a low-energy method and application of the silymarin and escin composition in anti-allergic and anti-inflammatory products. The method comprises the following steps: mixing silymarin, escin and a solvent, heating and stirring until the silymarin, escin and the solvent are dissolved, adding an emulsifier, slowly dropwise adding grease, finally adding the balance of water, and cooling. The invention provides a method for preparing a stable and transparent nano-emulsion by comprehensively utilizing a phase composition method and a phase transformation method without the aid of strong shearing effects such as high-pressure homogenization, ultrasound or microjet and the like, and provides a method for preparing the stable and transparent nano-emulsion by applying a pharmaceutical preparation to wounds of patients and facilitating efficient and mild relieving of inflammation and discomfort.

The invention relates to the technical field of gouty arthritis, and discloses a traditional Chinese medicine plaster for treating gouty arthritis and a preparation method thereof. The ointment comprises the following materials: 1 part of paniculate swallowwort root, 1 part of asarum, 1 part of borneol, 2 parts of costustoot, 2 parts of earthworm, 3 parts of ligusticum wallichii, 3 parts of radix clematidis, 3 parts of spina gleditsiae, 4 parts of raw rhubarb, 6 parts of mint, a proper amount of vaseline, a proper amount of sesame oil, a medical dressing plaster and a desensitization adhesive tape. According to the traditional Chinese medicine plaster for treating the gouty arthritis and the preparation method of the traditional Chinese medicine plaster, the traditional Chinese medicine plaster directly acts on an affected part, transdermal absorption is achieved, the local treatment effect can be rapidly achieved, pains and inflammations caused by the gouty arthritis are relieved, medicinal materials are smashed into ultra-micro powder of 300 meshes through an ultra-micro powder machine, and the traditional Chinese medicine plaster is prepared into the traditional Chinese medicine plaster for treating the gouty arthritis. Compared with an oral medicine, the external plaster can increase the surface area of the medicine and improve the permeability and absorption efficiency of the medicine, and compared with the oral medicine, the external plaster can reduce the stimulation of the medicine to gastrointestinal tracts and systemic side effects.

The invention relates to a degradable double-enzyme active nano-enzyme for treating diabetic foot ulcer, and aims to provide a novel efficient treatment scheme. The nano-enzyme has peroxidase-like and catalase-like dual-enzyme activity, is prepared by a specific chemical synthesis method, has good biodegradability, and can efficiently catalyze a reaction in a physiological environment to reduce drug resistance. Compared with a traditional treatment method, the nano-enzyme disclosed by the invention can be used for remarkably improving the treatment effect of the diabetic foot ulcer, accelerating the healing process and reducing the toxic and side effects on a human body and the manufacturing cost at the same time, and a safer and more effective treatment choice is provided for a patient with the diabetic foot ulcer.

The application discloses a whitening and freckle-removing composition containing white tomato and chases yellow grass, a preparation method and application thereof, and belongs to the technical field of food, wherein the whitening and freckle-removing composition is composed of white tomato powder and chases yellow grass powder with a weight ratio of 1-3:2-7. The preparation method comprises the following steps: (1) beating, separating, concentrating and drying white tomatoes to obtain white tomato powder; (2) soaking chases yellow grass in acidic water, performing solid-liquid separation, concentrating and drying the obtained clear liquid to obtain chases yellow grass powder; and (3) mixing the white tomato powder and the chases yellow grass powder. The application utilizes the combination of white tomatoes and chases yellow grass, and improves the preparation process of chases yellow grass, so that the two components produce a synergistic effect in inhibiting tyrosinase activity and inhibiting melanin production.

The present invention relates to the medical and food use of bile acid derivatives. Specifically, the present invention relates to the use of 3-oxoLCA in reducing oxidative stress and inflammation in pregnant mothers and their offspring. Specifically, the present invention relates to the use of 3-oxoLCA to reverse the effects of oxidative stress on pregnant mothers, in particular, to maintain fetal equal weight, significantly reduce placental and liver oxidative stress in pregnant mothers and the resulting inflammation or dysfunction of the placenta and liver, and to improve the intestinal flora imbalance of pregnant mothers. Further studies have found that 3-oxoLCA has long-term effects, in particular, can significantly reduce the effects of oxidative stress during pregnancy on oxidative stress and inflammation in the liver of offspring.

The invention belongs to the field of pharmaceutical preparations, and particularly relates to a sulfhydrylated hyaluronic acid drug-loaded hydrogel preparation and a preparation method and application thereof, and the preparation method comprises the following steps: preparing isorhamnetin nanocrystalline ISO-NCs by adopting an anti-solvent precipitation method; the preparation method comprises the following steps: constructing thiolated hyaluronic acid HA-SH responded by GSH; and uniformly embedding the ISO-NCs into the HA-SH hydrogel, so as to prepare the sulfhydrylated hyaluronic acid drug-loaded hydrogel preparation ISO-NCs-coated Gel, and preparing the sulfhydrylated hyaluronic acid drug-loaded hydrogel preparation ISO-NCs-coated Gel. The drug-loaded hydrogel preparation constructed by the invention can be used for targeted therapy of colon cancer.

The present invention discloses the application of N-acetyltransferase 10 or its coding gene as a target in the preparation of a drug for treating psoriasis, and belongs to the field of biomedicine technology. The present invention, through experiments, confirms for the first time that N-acetyltransferase 10 is highly expressed in psoriasis patient lesion tissue, and expression is elevated in a psoriasis keratinocyte model, and N-acetyltransferase 10 deficiency causes psoriasis keratinocyte proliferation to slow down, and the generation of inflammatory factors and chemokines is reduced. In animal experiments, N-acetyltransferase 10 inhibitor Remodelin can alleviate imiquimod-induced psoriasis mouse skin inflammation, including improving scales and lesion thickness, reducing the generation of inflammatory factors and chemokines, etc. Therefore, the present invention proposes to prepare a new target N-acetyltransferase 10 for treating psoriasis drugs, and N-acetyltransferase 10 or its coding gene as an intervention target has a clear effect on the treatment of psoriasis, and has good safety.

The invention discloses an anti-inflammatory polypeptide as well as a preparation method and application thereof. The amino acid sequence of the anti-inflammatory polypeptide is Gln-Phe-Gln-Phe (QFQF), and the anti-inflammatory polypeptide is derived from milk fat globule membrane protein and is tetrapeptide capable of being absorbed by intestinal tracts. According to the anti-inflammatory peptide, the amino acid sequence of the anti-inflammatory peptide is analyzed by LC-MS / MS, the anti-inflammatory peptide is synthesized to further verify the anti-inflammatory activity, the sequence of the anti-inflammatory peptide is determined, and the efficiency is improved; the milk fat globule membrane protein-derived anti-inflammatory polypeptide can be used for preparing functional preparations and reducing inflammation in a human body, and has a potential effect of regulating and controlling generation and development of inflammation. The polypeptide has very important significance for developing dairy products, animal feeds, health-care products, health-care foods and medicines with anti-inflammatory functions, and has a wide application prospect.

The invention discloses peroxide triglyceride rich in azelaic acid as well as a preparation method and application of the peroxide triglyceride. The preparation method of the peroxide triglyceride rich in azelaic acid comprises the following steps: S1, mixing oleic acid and triglyceride, introducing mixed gas of ozone and oxygen under a stirring condition, and reacting at 20-30 DEG C for 8-14 hours to obtain an intermediate product; and S2, introducing oxygen into the intermediate product at 70-95 DEG C, and reacting for 6-10 hours to obtain the peroxide triglyceride rich in azelaic acid. According to the preparation technology disclosed by the invention, mutual dissolution of azelaic acid and oil is realized, and the prepared peroxide triglyceride rich in azelaic acid has the effect of relieving inflammation, and can be used for preventing and repairing light damage, reducing color sink, reducing generation of pigments and promoting fading of the pigments. The composition can also be used for barrier repair of other diseases such as atopic dermatitis, wound surfaces and the like and prevention of color subsidence; the air permeability is better, the usability is good, and basically no side effect exists.

The invention provides application of miRNA-148a-3p in preparation of a medicine for relieving inflammation, and belongs to the technical field of biological medicine. In the invention, the miRNA-148a-3p can reduce the expression of p65 and up-regulate the expression level of SIRT1 by targeting Tp65 in a 3'untranslated region of the miRNA-148a-3p so as to relieve inflammatory response and pathological injury degree. Through verification, the miRNA-148a-3p can reduce the expression of p65, up-regulate the expression of SIRT1 gene and inhibit the expression of proinflammatory factors in intestinal tracts of dextran sodium sulfate induced colitis model mice so as to relieve inflammation. Therefore, the camel milk exosome has an important protective effect on prevention and treatment of enteritis by regulating and controlling the miR-148a-3p / p65 / SIRT1 signal channel.

The present invention relates to a compound celecoxib capsule and a preparation method thereof, and belongs to the technical field of pharmaceutical preparations. The compound celecoxib capsule of the present invention is composed of celecoxib, a cyperus rotundus peel extract, a filler, a lubricant, and a capsule shell. The present invention uses a combination of a cyperus rotundus peel extract and celecoxib to exert significant advantages in treating arthritis, especially in relieving inflammation and joint symptoms. Animal experiments show that the combined use can exert a therapeutic effect superior to that of celecoxib alone.

This invention discloses a strain of *Lactococcus gasseri* LG3092 that produces the bacteriocin GarQ and effectively antagonizes multidrug-resistant *Helicobacter pylori*, and its applications. *Lactococcus gasseri* LG3092 was deposited at the Guangdong Provincial Microbial Culture Collection Center on October 30, 2023, with accession number GDMCC No: 63939. Studies have shown that LG3092 has the following beneficial effects: (1) it can produce the bacteriocin GarQ, effectively inhibiting the growth of *Helicobacter pylori* and other common pathogenic bacteria; (2) it has a high survival rate in the stomach, can colonize the stomach, and can compete with pathogenic bacteria for binding sites, effectively reducing the infection rate of *Helicobacter pylori* in the stomach; (3) it can improve the pathological state of the stomach and alleviate inflammation. Therefore, *Lactococcus gasseri* LG3092 has great application potential in the preparation of products for the prevention or treatment of *H. pylori*, especially multidrug-resistant *H. pylori* infection.

The invention relates to a daqin salt moisturizing composition and a preparation method thereof. The composition comprises the following ingredients: daqin salt and oligopeptides with whitening and anti-inflammatory functions. The daqin salt moisturizing composition of the invention adopts daqin salt as exfoliating particles instead of conventional scrub particles, and can kill bacteria and reduce inflammation, resist edema, and promote anti-inflammatory repair. The plant small molecule peptides in the composition have significant whitening and anti-inflammatory effects, can inhibit melanin production, brighten skin tone, even skin tone, and help repair damaged cells. The composition has good skin affinity, is mild and non-irritating, is suitable for various skin types, including sensitive skin, significantly improves skin quality, brightens skin tone, relieves inflammation, and deeply moisturizes, showing excellent skin care effects.

The invention relates to the technical field of cosmetics, in particular to exfoliating scrub cream and a preparation method thereof. The exfoliating scrub cream is prepared from the following raw materials in parts by mass: 0.03 to 0.04 part of an anti-allergy agent, 9.5 to 10.5 parts of a humectant, 0.8 to 1 part of xanthan gum, 7 to 9 parts of a surfactant, 67 to 70 parts of scrub particles, 0.5 to 0.6 part of a preservative, 0.2 to 0.3 part of essence and 12 to 14 parts of deionized water. The exfoliating scrub cream disclosed by the invention not only has efficient exfoliating and cleaning functions, but also can gently care skin and provide lasting moisturizing and nourishing effects, has multiple effects of resisting allergy and oxidation, and is a skin care product with excellent comprehensive performance.

The present invention relates to the field of aerosol technology, and more particularly to a moisturizing aerosol and a preparation method thereof. Its technical scheme includes 0.8-3.2 parts of hyaluronic acid, 3-7 parts of glycerol, 1-3 parts of a penetration enhancer, 1-5 parts of grape seed oil, 1-3 parts of walnut oil, 0.5-1.5 parts of carnauba wax, 1.2-2.8 parts of cornflower extract, 0.2-0.8 parts of cholesterol, 1.5-4.5 parts of an emulsifier, and 65-98 parts of deionized water. The moisturizing aerosol prepared by the present invention can enhance the permeability and absorptivity of a moisturizer, so that it can better penetrate into the deep layer of the skin, provide a lasting moisturizing effect, and simultaneously control excessive oil secretion of the skin, regulate the oil balance of the skin, control excessive oil secretion, and keep the skin soft and refreshing.

The invention discloses application of scylla serrata dodecapeptide in preparation of a skin relieving composition. The amino acid sequence of the scylla serrata dodecapeptide is as shown in SEQ ID NO.01. The invention further discloses a preparation method of the scylla serrata dodecapeptide. The blue crab dodecapeptide can effectively inhibit polarization of LPS-induced mouse macrophages RAW 264.7 to type 1 macrophages, secretion of proinflammatory factors and increase secretion of anti-inflammatory factors, can effectively relieve irritation of SDS to zebra fish embryos, does not show cytotoxicity to the mouse macrophages RAW 264.7, does not have an obvious stimulation effect on the zebra fish embryos, and can be used for preparing the anti-inflammatory and anti-inflammatory drugs. The traditional Chinese medicine composition has the effect of relieving inflammation and is relatively good in safety.

The utility model relates to the field of medical instruments, in particular to a disposable crissum postoperative nursing pad. The utility model provides a disposable crissum postoperative nursing pad which can inject water to perform hot compress or cold compress on a patient when the disposable crissum postoperative nursing pad is pasted for use, relieve inflammation, swelling and pain, reduce bleeding, improve use comfort and promote wound healing. A disposable crissum postoperative nursing pad comprises a breathable pad, a first sticking sheet and the like, and the upper side of the rear portion of the breathable pad is connected with the first sticking sheet. Cold water or hot water is poured into the water injection pipe and then enters the water bag for water injection, then the anti-overflow screw cover is rotated to be movably installed for sealing, then the device is pasted on trousers for use, hot compress or cold compress is carried out through hot water or cold water, and therefore when the device is pasted for use, water injection can be carried out on a patient for hot compress or cold compress. Inflammation, swelling and pain are relieved, bleeding is reduced, the use comfort is improved, and wound healing is promoted.

The invention belongs to the technical field of biomedicine, and particularly relates to a preparation method and application of baicalein supramolecular nanobelts.The baicalein supramolecular nanobelt for relieving intestinal injury of crisp tilapia mossambica is prepared according to the following steps that baicalein and dimethyl sulfoxide are mixed, then water is added for stirring, then centrifugal cleaning and dialysis are conducted with purified water, and the baicalein supramolecular nanobeltssambica is obtained; and freezing and drying to obtain the baicalein supermolecule nanobelt. The water solubility and bioavailability of the baicalein supramolecular nanobelt are remarkably improved, the crisp meat quality of tilapia can be kept, and intestinal inflammation can be relieved.

The invention aims to provide the hair essence production formula, various components with the effects of enhancing hair quality and improving scalp health are accurately proportioned, meanwhile, the synergistic effect is shown in the aspect of activating the activity of tyrosinase, and the prepared essence can effectively increase the black hair rate and has an excellent effect of turning white hair into black.

The present invention discloses an environmentally responsive layer-by-layer self-assembled nanocomposite, the nanocomposite includes black phosphorus nanosheets BP, polymetformin PM, hyaluronic acid HA and P3 peptide-modified HA, the nanocomposite is a layer-clad structure, the core is a black phosphorus nanosheet, the middle layer is polymetformin, and the outer layer is hyaluronic acid and P3 peptide-modified HA. The nanocomposite relies on P3 peptide and HA to dual-target adipose tissue, P3-HA can respond to adipose tissue MMP-2 enzyme degradation and expose internal HA, HA can target and bind to multiple CD44 receptors on the surface of agglomerated adipocytes and macrophages, thereby synergizing with PM to inhibit adipogenic gene expression of adipocytes and reduce fat content, reduce the expression level of macrophage inflammatory factors and relieve inflammation, and the photothermal effect of BP also helps to reduce fat accumulation. The environmentally responsive layer-by-layer self-assembled nanocomposite provided by the present invention has good application prospects in obesity treatment drugs.

The utility model belongs to the technical field of medical care, and particularly relates to a functional dressing applied after photodynamic therapy, which comprises an application body, and the application body comprises a waterproof layer, a light shielding layer, a sealing and bonding layer and an antibacterial layer. The patch is adhered to the affected part of the skin through the sealing adhesive layer, the waterproof layer keeps the internal environment dry and stable, the light shielding layer can block the stimulation of external light to the damaged skin, the antibacterial layer can effectively inhibit the growth of bacteria, and the hydrogel cooling composite film layer has excellent water absorption and water retention performance. The hydrogel cooling composite film layer can rapidly absorb heat on the skin surface and take away the heat through the evaporation effect of water, so that rapid cooling is achieved, the cooling mode is high in speed and long in duration time, the wound repairing layer can stimulate proliferation and differentiation of cells, the healing process of a wound is accelerated, and the healing effect of the wound is improved. And the components can also provide nutrients and moisture required by wounds and promote skin regeneration.

The invention provides nicotinamide whitening, moisturizing and beautifying cream and a preparation method thereof, and belongs to the technical field of cosmetics. According to the nicotinamide whitening, moisturizing and beautifying cream, the nicotinamide derivative, the fermentation extract and other components are added, so that the prepared nicotinamide whitening, moisturizing and beautifying cream has better functions of whitening, moisturizing, diminishing inflammation, resisting bacteria and enhancing skin barrier, the absorption of active components by skin can be improved, the addition amount of the active components is reduced, the cost is reduced, the effect is improved, and the nicotinamide whitening, moisturizing and beautifying cream has a good application prospect. Wide application prospects are realized.

The invention belongs to the technical field of traditional Chinese medicines, particularly relates to eye drops and a preparation method thereof, and adopts the technical scheme that the eye drops are prepared from calyx seu fructus physalis and purified water. The calyx seu fructus physalis in the components of the eye drops has a natural anti-inflammatory attribute, so that the eye drops are beneficial to relieving eye inflammation and discomfort, improving eye health and improving eyesight; the eye drops are only prepared from calyx seu fructus physalis and water, so that the use of chemical additives is reduced, and the eye drops are more natural, safer and suitable for long-term use; the calyx seu fructus physalis extract in the eye drops can help to keep eyes moist, prevent xerophthalmia and improve the comfort level of a user; due to the natural component formula, the eye drops are mild and non-irritant, and are suitable for sensitive people and users who often use the eye drops.