368 results about "Xerophthalmia" patented technology

The invention provides a method and a device for protecting eyesight. The method comprises the following steps that: a mobile terminal detects acquired eye image information, wherein the eye image information comprises opening state information of eyes; and when the condition that the opening states of the eyes keep a first preset period of time is detected, the mobile terminal performs eyesight protection operation. Due to the adoption of the technical scheme provided by the invention, the problems that xerophthalmia or hypopsia and the like can be caused by asthenopia which is easy to cause because a user watches a screen of the mobile terminal for a long time when using a certain application program of the mobile terminal, for example, the user does not blink the eyes for a long time when playing games or reading electronic books in the prior art are solved, so that the effect that the eyesight of the user can be protected when the mobile terminal is used by the user is achieved, the mobile terminal is more humanized and user experience effects are improved.

The invention relates to the field of Chinese medicine, and discloses a Chinese medicinal composition for preventing and treating xerophthalmia. The composition comprises chrysanthemums, medlar, phellodendron, red sage roots, pearls, borneol and menthol. The medicinal composition preferably comprises the following in part by weight: 2.5 to 3 parts of chrysanthemums, 2.5 to 3 parts of medlar, 2.5 to 3 parts of phellodendron, 1.5 to 2 parts of red sage roots, 0.08 to 0.1 parts of pearls, 0.08 to 0.1 parts of borneol and 0.15 to 0.2parts of menthol. The invention also provides a wet application of the Chinese medicinal composition and a preparation method thereof. The Chinese medicinal composition has the effects of clearing heat, releasing toxin and moistening dryness, enables people to feel cool and comfortable after using the composition, and has the advantages of no toxic or side effects, easy absorption, quick response, good curative effect and good application prospects.

The invention belongs to a pharmaceutical composition, in particular a pharmaceutical composition for treating xerophthalmia. The pharmaceutical composition provided by the invention is prepared from effective amounts of radix rehmanniae, figwort, ophiopogon root, dendrobium, rhizoma anemarrhenae, radix trichosanthis, chrysanthemum, mulberry leaf, pipewort, radix sileris and other raw medicines. The invention solves the problems of short action time, limited treatment, poor treatment effect and the like in the prior art. The pharmaceutical composition has the advantages of small drug toxicity, obvious treatment effect and the like.

The invention discloses a comprehensive analysis system for xerophthalmia. The comprehensive analysis system comprises an imaging system, an analyzing system and a video terminal, wherein the imaging system comprises a lighting source, an imaging assembly, a control panel and a camera shooting module, the lighting source penetrates through the imaging assembly and irradiates the eyes of a patient, and the camera shooting module carries out imaging on the eyes of the patient, and transmits the generated image to a PC machine through a USB interface; the analyzing system is arranged at the PC machine end, and comprises a communication module, an image data collecting module, a tear film breakup time check module, a lacrimal rivus height measuring module, a meibomian gland image collecting and enhancing module, a lipid layer analyzing module, a data analyzing module and an information management output module; the video terminal is connected with the analyzing system. With the comprehensive analysis system for xerophthalmia provided by the invention, the functions of tear film breakup time statistics checking, lacrimal rivus height measurement, meibomian gland image collection and enhancement, human eye lipid layer analysis, and the like are realized, a basis is provided for the clinical diagnosis for xerophthalmia, and the comprehensive analysis system is applied to the medical treatment in the relevant fields of clinical diagnosis of the ophtalmology department.

The present invention relates to a vitamin A liposome artificial tears eye drops for preventing and curing xerophthalmia and ophthalmokopia. Its composition includes fat-soluble vitamin A, liposome encapsulating material, vitamin E and artificial tears hydrated liquor, in which the fat-soluble vitamin A is vitamin A palmitate or vitamin A acetate, the liposome encapsulating material is soya bean lecithin and cholesterol, and the composition of artificial tears hydrated liquor includes sodium hydrogen carbonate, sodium chloride, glucose, potassium chloride, calcium chloride and water. Besides, according to requirements one or several kinds of auxiliary components of menthanol, PVP and HPMC, etc. also can be added.

The invention relates to a cyclosporine-containing composition and a preparation method thereof. The compound eye drops are prepared from cyclosporine, anti-inflammatory or antibiotic drugs, a surfactant, a stabilizer, a thickener, an isoosmotic adjusting agent, a pH adjusting agentr and water or oil, the preparation is a mixed suspension agent or an emulsion, and one or two of a high pressure homogenization method and a wet grinding technique is/are combined for use in the preparation method. The cyclosporine compound eye drops have the advantages that the ophthalmic tolerance is excellent, the drug utilization degree is high, the tear secretion of people suffering from xerophthalmia can be effectively improved, the tear film is stabilized, the anti-inflammation function of the anti-inflammatory or antibiotic drugs and the immunoregulation function of cyclosporine can be synergistically exerted, xerophthalmia can be effectively treated, and the compound eye drops have a better treatment effect compared with the separate application of cyclosporine.

The invention provides a composition containing an effective dose of antofloxacin or a pharmaceutically acceptable salt thereof or/and an effective dose of an anti-inflammatory steroid or non-steroidanti-inflammatory medicine or/and an effective dose of a water-retaining or wetting agent or an anti-xerophthalmia medicine, and an application of the composition in the preparation of an externally used antofloxacin medicine for local eyes or ears or noses or skins, used for preventing or treating conjunctivitis, angular blepharitis, keratitis, scleritis, trachoma, xerophthalmia, cataract, otitisexterna, otitis media, folliculitis and impetigo in humans or mammals. The medicine obtained in the invention has good curative effects or good therapeutic compliance.

The present invention provides a liquid preparation composition comprising a solvent and a surfactant dissolving in the solvent, the surface tension of the liquid preparation composition is less than 60mN / m, and the pH of the liquid preparation composition is 5.0-7.4. The present invention also discloses a preparation method of the liquid preparation composition and use of the liquid preparation composition in treatment of otitis media, otitis externa, rhinitis, nasosinusitis, lower respiratory tract inflammation, xerostomia, xerophthalmia and dry noses. The present invention also discloses a preparation comprising the liquid preparation composition. The liquid preparation composition can effectively relieve the otitis media, the otitis externa, the rhinitis, the nasosinusitis, the lower respiratory tract inflammation, the xerostomia, the xerophthalmia, the dry noses and other symptoms, can be used in the form of sprays or liquid droplets, can be applied to an effective site without use of a propellant or an atomization device, is easy to operate, and can effectively avoid stimulation and injury caused by the propellant and use inconvenience of the atomization device.

The invention discloses a traditional Chinese medicine eye care mask and relates to the technical field of eye care masks. A preparation method of the traditional Chinese medicine eye care mask comprises the steps that ganoderma, flos chrysanthemi indici, licorice roots, cassia seeds, radix angelicae dahuricae, cortex phellodendri, Chinese wolfberry fruits, radix ophiopogonis, flos lonicerae, rehmannia roots, folium mori, chuanxiong rhizomas, kudzu vine roots and mint leaves are placed in distilled water with the weight five times that of the medicine mixture for soaking, then the mixture is decocted for 30-40 minutes, filtrate is filtered, and the filtrate is subjected to reduced pressure concentration, so that a concentrated solution is obtained for use; silk patch cloth is cut to be oval and then soaked into the concentrated solution, high temperature sterilization and disinfection are conducted, then each piece of the silk patch cloth is encapsulated into an aluminum plastic film-coated bag together with the concentrated solution, sealing is conducted, and the traditional Chinese medicine eye care mask is obtained. According to the traditional Chinese medicine eye care mask, traditional Chinese medicine constituents which have the functions of invigorating blood circulation, dispelling wind, clearing away heat, calming the liver and improving eyesight are added to the formula, and multiple effects of treating pseudomyopia, preventing and treating xerophthalmia, protecting eyes, improving eyesight and the like are achieved. Meanwhile, such asthenopia symptoms as visual impairment, eye tiredness, photaesthesia, ache, tears-down, foreign body sensation, dry eyes and eye spasm can be improved or alleviated, and compared with traditional medicinal treatment, the eye care mask is more convenient and faster to use.

The invention provides an application of etimicin and pharmacologically acceptable salt or inclusion compounds thereof in preparation of a local eye medicine or medicine composition for preventing ortreating eye diseases, xerophthalmia or dry eye syndromes, caused by conjunctivitis, angular blepharitis, keratitis, scleritis, trachoma and sensitive bacterium infection, of people or mammals. Eye preparations comprise eye drops, eye gel and the like. The medicine has better safety and effectiveness in a certain range.

The invention relates to an eye formulation administering system containing lecithin and sodium hyaluronic acid and its preparing method, wherein the system can directly serve as artificial tears to be applied to the treatment of xerophthalmia and other ophthalmology diseases. The system may also include other active constituents.

The invention discloses a contact lens for treating xerophthalmia. The contact lens is a ball coronary-shaped corneal contact lens (1) which is mainly composed of a soft layer (7) and a hard layer (8), wherein the two parts are made in manners of plane bonding and hot-press molding; a micro-fluid channel (3) and a hollow cavity (4) are formed inside the contact lens; the hollow cavity (4) is filled with a liquid medicine (5); one end of the micro-fluid channel (3) is communicated with the hollow cavity (4); and the other end of the micro-fluid channel (3) is communicated with a liquid outlet (2), and thus the micro-fluid channel (3) is communicated with outside of the corneal contact lens (1). Through reasonable arrangement and improvement of materials of contact lenses and internal structures of lens pieces, the contact lens is used as a medicine delivery system, and compared with a conventional treatment mode of eye drops, the contact lens has the advantages that multiple inconveniences of conventional eye drop treatment modes are overcome, the biological utilization rates of medicines are effectively increased, the retention times of the medicines on corneas are prolonged, and automatic and long-lasting medicine administration treatment on patients suffering from xerophthalmia is achieved.

The invention discloses an external spraying agent and/or eye drop of compound oil nano-emulsion as well as preparation method thereof. The pH value of the spraying agent and/or eye drop is 3-9. The spraying agent and/or eye drop comprise the following components according to the weight portion: 5-15 of compound oil, 0.5-2.0 of phospholipid, 0.5-3.0 of propanetriol, sodium hydroxide and medicinal water, wherein the compound oil comprises the following components: (1) zedoary turmeric oil and/or peppermint oil, and (2) soybean oil and/or castor oil. The mass ratio of the (1) and the (2) in the compound oil is 1:99-30:70. The spraying agent of the compound oil nano-emulsion, which is prepared by the invention, is used for antibiosis, inflammation diminishing and wound healing in the process of curing burn and scald. The eye drop of the compound oil nano-emulsion is used for curing eye strain, xerophthalmia and eye inflammation.

The invention provides application of a pharmaceutical composition containing recombinant human prothymosin beta4 in preparation of a medicine for treating eye diseases and particularly application in the treatment of xerophthalmia. The pharmaceutical composition is characterized in that the concentration of the recombinant human prothymosin beta4 is 1ug/mL-1000ug/mL. The invention further provides the pharmaceutical composition containing pharmaceutically acceptable carriers.

The invention discloses a medicine composition for treating xerophthalmia. The medicine composition is a preparation prepared from the following crude drugs in weight ratio: 12-18 parts of rhizoma polygonati, 8-12 parts of radix glehniae, 8-12 parts of medlar and 8-12 parts of chrysanthemum. According to the medicine composition disclosed by the invention, the rhizoma polygonati, the radix glehniae, the medlar and the chrysanthemum are reasonably combined, and thus, symptoms, such as dryness, foreign body sensation and hyperemia of bulbar conjunctiva of eyes, can be obviously improved. The medicine composition can be effectively used for treating xerophthalmia caused by video terminals, middle-aged and elderly xerophthalmia or diabetic xerophthalmia. Moreover, the clinical effect of the medicine composition is obviously superior to that of the Western medicine Tears Natural II group and the traditional Chinese medical science acupuncture group. The medicine composition is high in safety and good economic benefit, and a new medicine selection is provided for clinically treating the xerophthalmia.

The present invention provides a composition containing an effective dose of etimicin or a pharmaceutically acceptable salt thereof and an anti-inflammatory effective dose of dexamethasone or a pharmaceutically acceptable derivative thereof, and applications of the composition in preparation of topical ophthalmic or aural or nasal or skin external application drugs for prevention or treatment of human or mammalian conjunctivitis, angular blepharitis, keratitis, scleritis, trachoma, xerophthalmia, otitis externa, otitis media, folliculitis, furuncle, impetigo and the like. According to the present invention, the drug has good safety and good efficacy compared to etimicin.

The invention relates to an application of an HMGCoA reductase inhibitor in preparation of a medicine used for treating xerophthalmia and belongs to the field of medicines. The inventor finds that a frequently-used lipid regulation medicine, the HMGCoA reductase inhibitor, can obviously prolong SIT time and BUT time and obviously reduce an FLS score when being used for treating the xerophthalmia, and the HMGCoA reductase inhibitor is better than ciclosporin or artificial tears in the aspect of improving the indexes, wherein simvastatin and lovastatin have the best treatment effect. The HMGCoA reductase inhibitor also can be prepared into oral preparation used for treatment or adjuvant therapy of the xerophthalmia. The HMGCoA reductase inhibitor has a definite curative effect and less toxic and side effects, compliance of a patient is high, and clinical ophthalmic drugs are further enriched.

The invention relates to an active substance of cordyceps cicadae, a preparation method of the active substance, pharmaceutical composition containing the active substance and application of the active substance. The active substance of the cordyceps cicadae is used for preventing and/or treating xerophthalmia and can be prepared with a method comprising steps as follows: cordyceps cicadae mycelia are taken and cultured on a plate medium for 5-14 days at the temperature of 15-35 DEG C; the cultured cordyceps cicadae mycelia are inoculated into a flask and cultured for a few days under the conditions that the temperature is 15-35 DEG C and the pH is 2-8; the cultured cordyceps cicadae mycelia are inoculated into a fermentation tank and cultured for 3-5 days under the conditions that the temperature is 15-35 DEG C, the pH is 2-8, the tank pressure is 0.5-1.0 kg/cm<2> and the ventilation rate is 0.01-1.5 VVM, and cordyceps cicadae mycelium fermentation broth is formed; the fermentation broth is subjected to freeze drying and ground into powder, and cordyceps cicadae mycelium freeze-dried powder is formed; the freeze-dried powder is extracted with a solvent, and a cordyceps cicadae mycelium extract solution is formed; the extract solution is dried, and the active substance of the cordyceps cicadae is obtained. The active substance of the cordyceps cicadae can be used for preparing the pharmaceutical composition for preventing and/or treating xerophthalmia.

The present invention provides a preparation composition comprising a solvent, a drug component and a surfactant, the preparation composition is emulsion, surfactant-containing liquid droplets are distributed in the solvent, the volume average particle diameter of the liquid droplet is 100mum or less, the drug component comprises one drug or more drugs for treatment of otitis media, otitis externa, rhinitis, nasosinusitis, lower respiratory tract inflammation, xerostomia, xerophthalmia and dry noses, the surface tension of the preparation composition is less than 60mN / m, and the absolute value of the zeta potential is more than 15mV. The present invention also discloses a preparation method and use of the preparation composition. The preparation composition can relieve the otitis media, the otitis externa, the rhinitis, the nasosinusitis, the lower respiratory tract inflammation, the xerostomia, the xerophthalmia, the dry noses and other symptoms, can be used in the form of sprays or liquid droplets, can be applied to an effective site without use of a propellant or an atomization device, is easy to operate, and can effectively avoid stimulation and injury caused by the propellant and use inconvenience of the atomization device.